A biological sample collection system can include a sample collection vessel having a sample collection chamber with an opening configured to receive a biological sample into the sample collection chamber. The biological sample collection system can additionally include a selectively movable sleeve valve configured to associate with the opening of the sample collection chamber. The biological sample collection system can additionally include a sealing cap that is configured to associate with the selectively movable sleeve valve and with the sample collection vessel. The sealing cap can include a reagent chamber having reagent(s) stored therein, and when the sealing cap is associated with the sample collection vessel, the selectively movable sleeve valve opens, dispensing the reagent(s) into the sample collection chamber.

The present invention relates to a multisystem for simultaneously performing a biochemical examination and a blood test or an immunity test, the multisystem including a multi-disc in which a biochemical examination unit, a blood testing unit and an immunity test unit are divided and formed in a fan shape based on a rotation center. There is an effect that it is possible to perform all of a biochemical examination for measuring concentration values of biochemical components of serum to diagnose vital functions, a blood testing for separating blood samples to measure and test the number and deformation of red blood cells or white blood cells, and an immunity test for measuring an antigen-antibody reaction of serum to diagnose and test cancer or viruses in one device at the same time by using the multi-disc according to the present invention.

A centrifugal microfluidic system. The centrifugal microfluidic system includes a top layer, a bottom layer, and a middle layer. The middle layer may include an inlet chamber, a radial guide channel, a moveable magnet, a first connecting channel, a sealing beam, a target chamber, a second connecting channel, and a first stationary magnet. When the middle layer rotates around the center of the middle layer with a speed less than a threshold rotational speed, the fluid sample is prevented from flowing to the target chamber from the inlet chamber. When the middle layer rotates around the center of the middle layer with a speed greater than the threshold rotational speed, the fluid sample is allowed to flow to the target chamber from the inlet chamber through the first connecting channel and the second connecting channel.

A cartridge to be installed in a detection device for detecting light generated from a measurement sample containing a test substance is provided. The cartridge includes: a plurality of detection chambers fluidly isolated from each other and each receiving a measurement sample; and a transmission suppression unit provided between one detection chamber and another detection chamber of the plurality of detection chambers, and configured to suppress transmission of light generated from a measurement sample in the one detection chamber to the another detection chamber.

The present disclosure relates to a device capable of adjusting the pH of a sample and provides a device comprising microbeads capable of adjusting the pH of a sample to a predetermined value. The device comprises microbeads enabling adjustment to different pH values in each of a plurality of channels, and enables adjustment of the pH of the sample to a plurality of different pH values simultaneously upon injection of the sample.

Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.

Devices and methods for handling liquids are provided. The devices and methods make use of specifically controlled centrifugal forces to drive liquid flow between two cavities connected by a conduit such that as liquid flows into the second cavity, a gas volume is trapped in the second cavity and a pressure of the gas increases, allowing for pneumatic control of liquid flow. The devices and methods facilitate one or more of the mixing, metering and sequencing of liquids, for example on a microfluidic device.

An analysis device includes a turntable holding a substrate, an optical pickup driven in a direction perpendicular to a rotation axis of the turntable and configured to emit laser light to reaction regions and to receive reflected light from the respective reaction regions, an optical pickup drive circuit, and a controller. The reaction regions are formed at positions different from the center of the substrate. The center of the substrate is located on the rotation axis of the turntable. The optical pickup detects a reception level of the reflected light to generate a light reception level signal. The controller controls a turntable drive circuit to rotate the substrate, controls the optical pickup drive circuit to drive the optical pickup, and specifies the respective reaction regions in accordance with a positional information signal and the light reception level signal.

Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.

Provided is a microfluidic device to more easily and effectively operate a valve by improving the structure of valves for controlling a fluid flow more simply and efficiently, which comprises a platform having at least one chamber, at least one flow channel connected to the chambers and transfer fluid, and a valve which opens or closes the flow channel, wherein the valve comprises a body installed in the platform, a blocking plate installed in the body and positioned to face the flow channel to selectively blocks the flow channel, a pressing rod installed to be movable at the inside of the body to press the blocking plate, and a fixing unit installed at the body and fix the pressing rod at a blocking plate pressing position.