The invention relates to a door assembly (1) allowing a sealed transfer between two enclosed volumes, comprising a flange (2) arranged to delimit an opening in one of the enclosed volumes, and a door (4) that extends along an axis (C) and is hingedly fastened to/mounted on the flange (2) so as to move from a closed position in which the door (4) closes the passage opening (3), into an open position, characterized in that the door (4) is fastened to the flange (2) by a double-joint linkage mechanism (5) comprising a first joint (6) arranged to allow a rotational movement about an axis (A) perpendicularly to the axis (C) of the door by a maximum of 30 degrees in relation to the plane of the passage opening (3), and a second joint (7) arranged to allow a rotational movement about an axis (B) parallel to the axis (C) of the door.

The present invention provides a glove/logging system capable of accurately determining periods for glove airtightness inspection and replacement and improving the safety of a work glove in use and the work efficiency by recording and storing the status of use such as the operator name, the frequency of use, the period of use, and the details of work for an individual pair of work gloves attached to an equipment such as an isolator, and retroactively checking improper work and equipment abnormalities by tracing glove operations upon occurrence of operational abnormalities.

The glove/logging system is configured to record and store information on the status of use for a work glove, and include an operator tag, a glove tag, a reader for reading information from the tags, and an information device for recording and storing information. The reader is configured to receive information from the operator tag that passes through the reception region or stops therein or the glove tag via the antenna to communicate the information with the information device.

The invention relates to a door assembly (1) for a sealed enclosure, said enclosure comprising a wall having a wall portion (20) defining at least one passage opening therein, said door assembly (1) comprising a flange (3) intended for being attached to the wall portion (20), characterized in that the flange (3) comprises two flange elements (3a, 3b) assembled together, one of the flange elements (3a) defining a ring inside the enclosure, the other flange element (3b) defining a ring outside the enclosure, and means for clamping at least one of the two flange elements (3a, 3b) against the wall portion (20).

The present invention provides a work hood that allows for free rotation in a work box to provide a wide work area and easy decontamination of a sealing portion present at the boundary between the work hood and the work box. A rotation support for rotatably supporting the entire half suit is provided. The rotation support includes a base portion, a rotating portion, a bearing portion, a sealing member, and a communication hole. The base portion is airtightly and annularly provided around an opening, and the rotating portion is provided around the base portion through the bearing portion, with a hem portion of the half suit being fixed to the rotating portion. The sealing member is annularly provided in an annular space formed by the base portion and the rotating portion so as to separate the work box and the external environment. The communication hole is provided so as to lead to the external environmental side from the annular small space side formed by the sealing member together with the base portion, the rotating portion, and the bearing portion, and is connected to a supply means for supplying a decontamination gas and the like to the inside of the small space and to a suction means for sucking clean air and the like from the inside of the small space.

The invention relates to a sealed container (1) comprising a container body (2) having a through-hole (8) that is delimited by a flange and is closed by a removable door (7) mounted on the flange, an annular seal (13) located between the flange and the door (7), the flange, the door (7) and the seal forming a sealed connection device that can be connected to a complementary connection device on a sterile enclosure by means of bayonet connection means in order to allow sterile communication between the sealed container and the sterile enclosure, characterized in that the seal (13) comprises, on its inner peripheral circumference, an annular attachment bead (130) for attaching the door (7) to the flange inserted into a notch (70) on the door (7).

The present invention relates to a biological (eg cell) processing assembly comprising an aseptic chamber with apertures adapted for gloves to fit and an incubation chamber connectable to aseptic chamber with transfer hatches, doors secured by multi-walls and inflatable seals, stepped collars for tight closure of doors and closed interaction between the chambers. From the aseptic chamber it can be reached through into incubation chamber. There is a docking spigot on outlet wall to interact with stepped collar to define transfer port between the chambers and a disinfectant delivery device to disinfect transfer port.

The embodiments of the present disclosure provide a method for producing Ac-225 from Ra-226, comprising submitting Ra-226 to a photo-nuclear process, collecting an electrochemical precipitation of an Ac-225 on a cathode in a recipient, removing the cathode from the recipient after the electrochemical precipitation of the Ac-225, transferring the cathode to a hot cell environment, and extracting the Ac-225 from the cathode in the hot cell environment. The Ra-226 may comprise a liquid solution in the recipient, and submitting Ra-226 to the photo-nuclear process may comprise irradiating the Ra-226 to produce Ra-225. The Ra-225 may decay into Ac-225 upon irradiation of the Ra-226.

The invention relates to a door arrangement (1) for a door with a first enclosed volume, the arrangement permitting a sealed connection between the first enclosed volume and a second enclosed volume, and comprising a flange (2) defining passage opening and a passage axis (O) perpendicular to the opening plane, a door (4) pivotably mounted on the flange (2) and a chute for discharging (10) components which is movable between a discharge position in which the chute is positioned opposite the passage opening and a position in which the chute is spaced apart from the passage opening, the chute being attached to the flange (2) by means of a first double-jointed link mechanism (11) comprising a first link (12) arranged to permit a rotational movement about an axis (C) parallel to the passage axis (O) of the passage opening and a second link (13) arranged to permit a rotational movement about an axis (D) perpendicular to the passage axis (O) of the passage opening.

A biofabrication system includes a workstation and an articulating arm disposed within a work area of a biosafety cabinet. The workstation includes a stage for biofabrication. The biosafety cabinet includes an integration port that provides access to the work area through a wall of the biosafety cabinet. The articulating arm may be positioned to reach the workstation and the integration port.

A filling device for dosed filling of a product from a product storage container into product dose receiving containers provided in a disposable isolator so to be protected against contamination. The device includes means for holding the product storage container together with the contents outside of the disposable isolator. The device includes a controllable product removal device for a dosed removal of the product from the product storage container. The device includes a product dispensing device for the dosed dispensing of the product to the product dose receiving containers. The device includes a line assembly interconnecting the product storage container and the product dispensing device to conduct the product to the product dispensing device. The device includes at least one ultrasonic flowmeter outside of the disposable isolator fixed to the outside of the line assembly to detect the flow rate. The device includes a controller for measuring the product dose.