Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.

Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.

Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.

Full-automatic microelectronic printer comprising a printing platform, a control component, a feeding component, a camera component, a machine vision device, an ink droplet observation device, and a CAD/CAM system. The printing platform comprises a four-axis linkage system, a printing worktable, a base, a protective housing, an automatic ink cartridge turning device, and an automatic cleaning device; the feeding component comprises a switching control device, an ink cartridge, and an auxiliary processing component; the control component comprises a core control integrated circuit board, a plurality of drive control circuit boards, and a control module interface. The feeding component switches the ink cartridges and the auxiliary processing components to the printing platform in response to the control component which drives the ink cartridges and auxiliary processing components to print, and the protective housing removes fine particles and gas odors. CAD/CAM system assists in designing, generating, and sending instruction to the control component, printing platform, and feeding component to operate and realize full-automatic multi-layer printing.

Full-automatic microelectronic printer comprising a printing platform, a control component, a feeding component, a camera component, a machine vision device, an ink droplet observation device, and a CAD/CAM system. The printing platform comprises a four-axis linkage system, a printing worktable, a base, a protective housing, an automatic ink cartridge turning device, and an automatic cleaning device; the feeding component comprises a switching control device, an ink cartridge, and an auxiliary processing component; the control component comprises a core control integrated circuit board, a plurality of drive control circuit boards, and a control module interface. The feeding component switches the ink cartridges and the auxiliary processing components to the printing platform in response to the control component which drives the ink cartridges and auxiliary processing components to print, and the protective housing removes fine particles and gas odors. CAD/CAM system assists in designing, generating, and sending instruction to the control component, printing platform, and feeding component to operate and realize full-automatic multi-layer printing.

Described herein are compositions, methods, and systems for printing metal three-dimensional objects. In an example, described is a method of printing a three-dimensional object comprising: (i) depositing a metal powder build material, wherein the metal powder build material has an average particle size of from about 10 μm to about 250 μm; (ii) selectively applying a binder fluid on at least a portion of the metal powder build material, wherein the binder fluid comprises an aqueous liquid vehicle and latex polymer particles dispersed in the aqueous liquid vehicle; (iii) heating the selectively applied binder fluid on the metal powder build material to a temperature of from about 40° C. to about 180° C.; and (iv) repeating (i), (ii), and (iii) at least one time to form the three-dimensional object.

Described herein are compositions, methods, and systems for printing metal three-dimensional objects. In an example, described is a method of printing a three-dimensional object comprising: (i) depositing a metal powder build material, wherein the metal powder build material has an average particle size of from about 10 μm to about 250 μm; (ii) selectively applying a binder fluid on at least a portion of the metal powder build material, wherein the binder fluid comprises an aqueous liquid vehicle and latex polymer particles dispersed in the aqueous liquid vehicle; (iii) heating the selectively applied binder fluid on the metal powder build material to a temperature of from about 40° C. to about 180° C.; and (iv) repeating (i), (ii), and (iii) at least one time to form the three-dimensional object.

The invention relates to a method of additive manufacturing an object using a 3D printing apparatus, in which at least one layer or part of at least one layer is formed by an addition-crosslinking electro-conductive silicone composition comprising : (A) at least one organopolysiloxane compound A comprising, per molecule at least two C.sub.2- C.sub.6 alkenyl radicals bonded to silicon atoms, (B) at least one organohydrogenopolysiloxane compound B comprising, per molecule, at least two hydrogen atoms bonded to an identical or different silicon atom, (C) at least one catalyst C comprising at least one metal from the platinum group or the compound thereof, (D) at least one reinforcing silica filler D, (E) at least one thixotropic agent which is selected from compounds having epoxy group, (poly)ether group, and/or (poly)ester group, organopolysiloxane having an aryl group and mixtures thereof; (F) at least one electro-conductive filler F, which is selected from nickel coated carbon, preferably graphite, graphene or mixtures thereof; (G) optionally at least one crosslinking inhibitor G.

Embodiments of the present invention provide for a material extrusion system for three-dimensional (3D) printing/additive manufacturing. The material extrusion system can include a nozzle head configured to extrude a liquefied material of variable widths through an adjustable orifice, wherein the nozzle head can change sizes during a line to compensate for wider or thinner wall thickness.

Embodiments of the present invention provide for a material extrusion system for three-dimensional (3D) printing/additive manufacturing. The material extrusion system can include a nozzle head configured to extrude a liquefied material of variable widths through an adjustable orifice, wherein the nozzle head can change sizes during a line to compensate for wider or thinner wall thickness.