A container closure device comprises a closure unit (10) with a closure part (40) for opening and re-closing the container opening (23) multiple times, and an operating device (50) with an operating part (60) for actuating the closure part, wherein the operating part is rotatably disposed on the closure part and can be rotated from a locked position into an unlocked position. According to a first aspect, the operating part further comprises a first and a second locking portion (61, 62), which are configured in such a way that, in the locked position, the two locking portions extend beyond the container opening up to an opening limiting region (24) delimiting the container opening, and that, in the unlocked position, at least one of the two locking portions does not extend beyond the container opening up to the opening limiting region delimiting the container opening. Alternatively, a displacement mechanism is provided with which, by rotating the operating part relative to the closure part, one of the closure part or the operating part can be moved towards or away from the container wall in a direction substantially extending perpendicularly to the container wall, whereby the operating part and/or the closure part can be pressed against the container wall or detached from it. Alternatively, the closure unit comprises a fixing device (80) by means of which, in a fixed position, the closure part can be detachably fixed in the open position and by means of which, in a released position, the closure part can be pivoted between the closed and the open position.

A closure for a medical solution containing bottle, including a cap having a shroud disposed in closing relation to the neck and access opening of the bottle. The cap is removably connected to the bottle and may include a shrouded tamper evident indicator member connected to an interior surface of the shroud, at least initially inwardly of an open end of thereof in a non-visually observable location. Upon removal of the cap from the bottle and replacement thereof, the indicator member will be disposed exteriorly of the shroud in a visually observable location on the bottle. The closure may also include a spout integrated into the cap in a fixed, removable connection therewith, such that the spout is movable with the cap into closing relation of cap to the bottle neck and access opening.

A closure for a medical solution containing bottle, including a cap having a shroud disposed in closing relation to the neck and access opening of the bottle. The cap is removably connected to the bottle and may include a shrouded tamper evident indicator member connected to an interior surface of the shroud, at least initially inwardly of an open end of thereof in a non-visually observable location. Upon removal of the cap from the bottle and replacement thereof, the indicator member will be disposed exteriorly of the shroud in a visually observable location on the bottle. The closure may also include a spout integrated into the cap in a fixed, removable connection therewith, such that the spout is movable with the cap into closing relation of cap to the bottle neck and access opening.