The invention provides a novel method of coating the inside of a capillary with a polymeric material. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.

A wafer including a glass substrate is provided. The glass substrate includes a first surface defining a plane and including a surface roughness R.sub.a of approximately 0.3 nm in an outer via region and a second surface. The glass substrate defines a plurality of vias extending from the first surface. The plurality of vias each include an entrance defined by the first surface.

A method for producing a layer for coating the inner surface of a container and a glass or plastic container obtained by said method, wherein said container is suitable for containing products biocompatible with humans and/or animals. The method includes: forming a solution containing a solvent, water, a molecular precursor comprising alkoxy groups and an acid as a catalyst, mixing said solution to initiate hydrolysis and condensation, applying the resulting solution onto at least one portion of the inner surface of the container, while the solution is in the process of gelling, the resulting applied solution is then dried at a temperature for a predetermined time, before curing. The acid is citric acid, wherein said citric acid is at a concentration of less than 6 mol/l, and in that the solution comprises less than 1.5 units of precursor for each volume unit of acid.

A coated glass element includes: a glass surface; and a coating that coats at least part of the glass surface. The coating includes at least one layer. The at least one layer of the coating fulfills the following parameter: [Si.sub.2C.sub.5H.sub.15O.sub.2.sup.−].sub.20/[Si.sub.2C.sub.5H.sub.15O.sub.2.sup.−].sub.80≥1.0. [Si.sub.2C.sub.5H.sub.15O.sub.2.sup.−].sub.20 are counts of [Si.sub.2C.sub.5H.sub.15O.sub.2] ions, measured by a time-of-flight secondary ion mass spectrometry (TOF-SIMS), at 20% of a time a sputter gun beam needs to reach the glass surface and [Si.sub.2C.sub.5H.sub.15O.sub.2.sup.−].sub.80 are counts of [Si.sub.2C.sub.5H.sub.15O.sub.2.sup.−].sub.80 ions, measured by a TOF-SIMS, at 80% of a time a sputter gun beam needs to reach the glass surface.

A coated glass element includes: a glass surface and a coating that coats at least part of the glass surface. The coating has at least one layer. The at least one layer of the coating fulfills the following parameter: [Al.sup.+].sub.80/[Al.sup.+].sub.20≥1.8. [Al.sup.+].sub.20 are counts of [Al.sup.+] ions, measured by a time-of-flight secondary ion mass spectrometry (TOF-SIMS), at 20% of a time a sputter gun beam needs to reach the glass surface and [Al.sup.+].sub.80 are counts of [Al.sup.+] ions, measured by a TOF-SIMS, at 80% of a time a sputter gun beam needs to reach the glass surface.

A coated container includes: a container having a surface; and a coating applied to at least part of the surface to form a coated surface. Leaching of at least one of one or more types of ions or one or more types of compounds is determined by performing an alkaline treatment on at least part of the coated surface to obtain an alkaline treated surface and performing an acidic treatment on at least part of the alkaline treated surface to obtain an acidic treated surface. The leaching of the at least one of one or more types of ions or one or more types of compounds from the coated surface is 5.00 mg/l or less.

To provide glass including a colored layer and a manufacturing method thereof.

Provided is glass containing one or more glass components selected from the group consisting of Ti ions, Nb ions, W ions, and Bi ions. The glass includes a colored layer having an arbitrary shape.

Provided is an apparatus for coating containers having an inlet where containers are handed over to the apparatus, and an outlet where containers leave the apparatus, having at least one vacuum device for producing a vacuum, having at least one treatment station for coating containers with a plasma, wherein the treatment stations are in fluid connection with the vacuum device and wherein the treatment stations have at least one treatment device into which is able to be introduced into a container, wherein the apparatus has a first and a second transport device for transporting containers, wherein the first transport device feeds the containers at least indirectly to a treatment station, wherein the first transport device is able to be switched off at least temporarily, resulting in the feeding of containers to the treatment station being interrupted, and the second transport device being an at least sectionally linear transport device.

The present disclosure is directed to a vessel having a lumen defined at least in part by a wall, the wall having an interior surface facing the lumen, and the interior surface comprising a coating. The coating is configured to prevent the leaching of metal ions from the vessel wall into a fluid contained within the lumen and stored in contact with the coating. The vessels are used to store an aqueous drug product, typically an aqueous drug product containing an active agent and one or more excepients, such as a polysorbate stabilizer. The coated vessels are effective to reduce degradation of the active agent and/or one or more excipients, e.g. a polysorbate stabilizer.

An apparatus and to a method for treating layers using a plasma zone sealed from the outer atmospheric pressure are provided. The apparatus and method include a plasma reactor including a substrate carrier in form of a container receiving means, and a closing element that is joined with the substrate carrier by means of a lifting device.