Lithium disilicate apatite glass-ceramics are described which are characterized by a high chemical stability and can therefore be used in particular as restoration material in dentistry.

The present disclosure relates to mesoporous glasses as well as uses of such glasses, for example, as hemostats.

Compositions comprising a sol-gel derived glass, the sol-gel derived glass comprising two main components, the main components comprising a borate component and an alkaline earth metal component. Methods of making the compositions comprising combining precursor solutions containing boron ions, with alkaline earth metal ions to form a solution; gelling the solution to form a gel; drying the gel; and calcining the dried gel.

A bioactive glass composition for use in treating bone cancer includes 0.5-10 mol % gallium oxide or 1.0-20 mol % gallium nitrate/halide; 25 to 75 mol % silicon dioxide; 10 to 30 mol % calcium oxide and/or strontium oxide; up to 30 mol % sodium oxide; and up to 15 mol % phosphorous pentoxide. It may further comprise magnesium and/or potassium oxide. The bioactive glass composition may be positioned within a patient's bone post-surgery to promote apatite formation and to release gallium ions having a toxic effect on any remaining cancerous cells.

A glass, glass ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded be an amorphous shield. The shield serves to protect the internal porous microstructure of the shield while increasing the overall strength of the porous microstructure and improve the flowability of the beads either by themselves or in devices such as biologically degradable putty that would be used in bone or soft tissue augmentation or regeneration. The open porosity present inside the bead will allow for enhanced degradability in-vivo as compared to solid particles or spheres and also promote the growth of tissues including but not limited to all types of bone, soft tissue, blood vessels and nerves.

To provide a glass composition for glass fiber that includes biosolubility and can achieve long fiber formation. The glass composition for glass fiber of the present invention includes SiO.sub.2 in the range of 35.0 to 55.0% by mass, B.sub.2O.sub.3 in the range of 10.0 to 30.0% by mass, Al.sub.2O.sub.3 in the range of 14.5 to 30.0% by mass, and CaO and MgO in the range of 8.7 to 25.0% by mass in total, with respect to the total amount, and the content S of SiO.sub.2, the content B of B.sub.2O.sub.3, the content A of Al.sub.2O.sub.3, the content C of CaO, and the content M of MgO satisfy the following formula (1):

[00001]$\begin{array}{cc}11.3\le \text{S}\times \left(\text{C}+\text{M}\right)/\left(\text{A}+\text{B}\right)\le 20.7& \text{­­­(1)}\end{array}$

A silicate-based glass composition includes 15-65 wt. % SiO.sub.2, 15-50 wt. % CaO, 1-30 wt. % P.sub.2O.sub.5, and 1-20 wt. % ZrO.sub.2, such that the composition has a hydrolytic resistance of glass grains (HGB) of at most 3, when measured by International Organization for Standardization section 719 (ISO 719), and forms a bioactive crystalline phase in simulated body fluid.

Bioactive glass compositions, composites of the bioactive glass compositions with polymers, and 3D printable filaments made from the same, along with methods of making and using the same, are described. In some embodiments, the compositions, composites, and filaments have antibacterial activity.

The present invention relates to a glass ceramic composition comprising SiO.sub.2, Ca(OH).sub.2, CaF.sub.2, B.sub.2O.sub.3, MgO, and hydroxyapatite; a bioactive crystallized glass ceramic comprising each of CaSiO.sub.3, Ca.sub.10(PO.sub.4).sub.6(OH).sub.2, and CaMgSi.sub.2O.sub.6 in an amount of 20% to 60% by weight; an implant for early osseointegration comprising the glass ceramic; and a method for manufacturing the implant.

A silicate-based glass composition includes: 40-60 wt. % SiO.sub.2, 0-10 wt. % B.sub.2O.sub.3, 0.01-10 wt. % P.sub.2O.sub.5, 0-10 wt. % Al.sub.2O.sub.3, 0-5 wt. % Li.sub.2O, 10-30 wt. % Na.sub.2O, 0.01-15 wt. % K.sub.2O, 0.01-5 wt. % MgO, 15-30 wt. % CaO, 15-35 wt. % MO, and 15-30 wt. % R.sub.2O, such that MO is the sum of MgO, CaO, SrO, BeO, and BaO, and R.sub.2O is the sum of Na.sub.2O, K.sub.2O, Li.sub.2O, Rb.sub.2O, and Cs.sub.2O.