Disclosed herein are a novel organometallic compound and an organic light-emitting diode including same. More specifically, an organometallic compound represented by [Chemical Formula 1] and an organic light-emitting diode including same are provided.

Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.

The present disclosure provides compounds and methods useful for inhibiting SARM1 and/or treating and/or preventing axonal degeneration.

The present disclosure provides a nitrogen-containing compound, and an electronic component and an electronic device including the same, and belongs to the technical field of organic electroluminescence. The nitrogen-containing compound provided by the present disclosure has polycyclic conjugation properties, the compound has a core structure of fused indolocarbazole. The bond energy between the atoms is high, thus the compound has a good thermal stability, and facilitates solid state accumulation between the molecules. The electroluminescence device with the compound as a luminescent layer material has a long service life. According to the nitrogen-containing compound provided by the present disclosure with an indolocarbazole structure connecting with a nitrogen-containing group (triazine, pyridine and pyrimidine) and a benzoxazole or benzothiazole group respectively has a high dipole moment, thereby improving the polarity of the material. Using the nitrogen-containing compound of the present disclosure as the luminescent layer material of the organic electroluminescence device, the electron transport performance of the device can be improved, and the luminous efficiency and service life of the device can be improved.

Required are: a compound having high affinity for an emopamil binding protein; and a method for activating or inhibiting the emopamil binding protein, using such a compound. According to the present invention, provided is an emopamil binding protein binding agent comprising an alkyl ether derivative represented by the following formula [1] or a salt thereof: ##STR00001## wherein R.sup.1 and R.sup.2, which are the same or different, each represent a hydrogen atom, a halogen atom, an optionally substituted C.sub.1-6 alkyl group, an optionally substituted aryl group, etc.; R.sup.3 represents an optionally protected hydroxyl group, etc.; and m and n, which are the same or different, each represent an integer of 1 to 6.

The present specification relates to a double spiro structure compound, and an organic light emitting device comprising the same.

The present invention relates to a radioactive iodine-labeled pyrido[1,2-a]benzimidazole derivative compound represented by a definite general formula or a salt thereof, or a radiopharmaceutical comprising the same.

The present invention provides a system for the production of a radiopharmaceutical including a radiosynthesis apparatus and a disposable cassette. The system of the invention includes a device that enables a position on the cassette to be freed for inclusion of an additional reagent vial. With the system of the invention a broader range of radiochemical syntheses can be envisaged using the cassette.

The present invention relates to an automated radiosynthesis device adapted for the addition of multiple additional components. The automated radiosynthesis device of the invention enables a wider range of radiochemical synthetic processes to be carried out in an automated fashion.

The present disclosure discloses a deuterated organic compound and a formulation and an organic electronic device containing the same, wherein the deuterated organic compound has the following structural formula:

##STR00001##

wherein Ar is an aromatic or heteroaromatic structural unit, D is an electron donor group, A is an electron acceptor group, n and m are an integer between 1 and 6; and wherein for the organic compound, (S1-T1)≦0.25 eV, and at least one H atom of the organic compound is substituted by deuterium. The present disclosure achieves the improvement of the electroluminescence quantum efficiency and the lifetime of the organic compound by replacing the H atom in the organic compound with deuterium and having (S1-T1)≦0.35 eV, and the material of the present disclosure has a great application potential and application range due to its low cost and relatively simple synthesis process.