The invention relates to a method for preparing a suspension of a hydrochloride of an organic amine, comprising the following steps of (i) initially charging at least one organic solvent in a reaction vessel to form a liquid level, (ii) adding hydrogen chloride, (iii) adding the organic amine, wherein the organic amine is added below the liquid level present in the reaction vessel and steps (ii) and (iii) are at least partly carried out simultaneously. Furthermore, the present invention also relates to a method wherein the suspension obtained after step (iii) is reacted in a step (iv) with phosgene to obtain the organic isocyanate corresponding to the organic amine used, to the corresponding organic isocyanate and to the use of the organic isocyanate for producing polyisocyanates.

Quaternary ammonium compound compositions and more particularly quaternary ammonium compound compositions including greater than 25% by weight of a quaternary ammonium compound, methods for making same, fibrous structures employing same, and methods for treating fibrous structures with same are provided.

Quaternary ammonium compound compositions and more particularly quaternary ammonium compound compositions including greater than 25% by weight of a quaternary ammonium compound, methods for making same, fibrous structures employing same, and methods for treating fibrous structures with same are provided.

Quaternary ammonium compound compositions and more particularly quaternary ammonium compound compositions including greater than 25% by weight of a quaternary ammonium compound, methods for making same, fibrous structures employing same, and methods for treating fibrous structures with same are provided.

Quaternary ammonium compound compositions and more particularly quaternary ammonium compound compositions including greater than 25% by weight of a quaternary ammonium compound, methods for making same, fibrous structures employing same, and methods for treating fibrous structures with same are provided.

The present invention relates to a method of carrying out an organic reaction in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose.

The present invention relates to a method of carrying out an organic reaction in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose.

A method of preparation of trientine tetrahydrochloride crystals in which an anti-solvent at a feeding temperature is added into a trientine tetrahydrochloride solution and stirred for crystallization wherein the feeding temperature ranges from 50° C. to 75° C. and the anti-solvent is an alcohol solvent. A novel trientine tetrahydrochloride featuring XRPD peaks detected at 21.9, 24.8, 25.2, 28.0 and 35.6±0.1° 2θ for stable storage of a pharmaceutical composition manufactured with the trientine tetrahydrochloride.

A method of preparation of trientine tetrahydrochloride crystals in which an anti-solvent at a feeding temperature is added into a trientine tetrahydrochloride solution and stirred for crystallization wherein the feeding temperature ranges from 50° C. to 75° C. and the anti-solvent is an alcohol solvent. A novel trientine tetrahydrochloride featuring XRPD peaks detected at 21.9, 24.8, 25.2, 28.0 and 35.6±0.1° 2θ for stable storage of a pharmaceutical composition manufactured with the trientine tetrahydrochloride.

Quaternary ammonium compound compositions and more particularly quaternary ammonium compound compositions including greater than 25% by weight of a quaternary ammonium compound, methods for making same, fibrous structures employing same, and methods for treating fibrous structures with same are provided.