This invention relates to the preparation of N-(phosphonomethyl)glycine (“glyphosate”) from N-(phosphonomethyl)iminodiacetic acid (“PMIDA”), and more particularly to methods for control of the conversion of PMIDA, for the identification of reaction end points relating to PMIDA conversion and the preparation of glyphosate products having controlled PMIDA content. One such method involves obtaining a series of Fourier transform infrared (“FTIR”) analyses of the PMIDA content of the aqueous reaction medium or a sample thereof during the course of the reaction. From a plurality of FTIR analyses, a projection is made of the batch reaction time or continuous oxidation residence time within the oxidation reaction zone at which a target conversion or end point may be anticipated to be attained or is attained.

This invention relates to an improved electrodialysis method for preparing an amino acid from a salt of the amino acid utilizing a three-compartment bipolar membrane electrodialysis process wherein an aqueous electrolyte comprising an exogenous acid is added to the acid compartment of a three-compartment bipolar membrane apparatus. The exogenous acid is different than the amino acid and typically has a pKa less than the pKa of the amino acid.

A method includes removing glyphosate from a solution by contacting the solution with a mesoporous inorganic particle having an average pore size of greater than zero and less than about 50 nm, wherein the mesoporous inorganic particle is functionalized with a positively charged moiety selected from ammonium, amine and combinations thereof.

A novel compound has pharmacological activities comparable to those of Nahlsgen and is storable excellently stably. The compound can be produced by a method according to the present invention for producing an optically active 2-amino-phosphonoalkanoic acid salt. In the method, a starting material DL-2-amino-phosphonoalkanoic acid represented by Formula (1) or a hydrate thereof is reacted with an optically active basic compound other than an optically active lysine, to give a diastereomeric salt mixture including a first salt (including a hydrate salt) between a D-2-amino-phosphonoalkanoic acid represented by Formula (1-1) and the optically active basic compound, and a second salt (including a hydrate salt) between an L-2-amino-phosphonoalkanoic acid represented by Formula (1-2) and the optically active basic compound. The diastereomeric salt mixture is fractionally crystallized to isolate one of the first and second diastereomeric salts.

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This invention relates to processes for the removal of phosphorous from aqueous waste streams comprising phosphorous-containing compounds produced in the manufacture of glyphosate, in order to meet and typically exceed environmental regulations. More particularly, various embodiments of the present invention relate to the removal of phosphorous-containing compounds utilizing biological treatment system(s), oxidizing agent(s), and/or precipitant(s). The processes of the invention are also applicable to the removal of phosphorous compounds from phosphorous-containing waste streams other than those waste streams resulting from the manufacture of glyphosate.

This invention relates to the preparation of N-(phosphonomethyl)glycine (glyphosate) from N-(phosphonomethyl)iminodiacetic acid (PMIDA), and more particularly to methods for control of the conversion of PMIDA, for the identification of reaction end points relating to PMIDA conversion and the preparation of glyphosate products having controlled PMIDA content.

This invention relates to processes for the removal of phosphorous from aqueous waste streams comprising phosphorus-containing compounds produced in the manufacture of glyphosate, in order to meet and typically exceed environmental regulations. More particularly, various embodiments of the present invention relate to the removal of phosphorous-containing compounds utilizing biological treatment system(s), oxidizing agent(s), and/or precipitant(s). The processes of the invention are also applicable to the removal of phosphorous compounds from phosphorous-containing waste streams other than those waste streams resulting from the manufacture of glyphosate.

This disclosure relates to an improved electrodialysis method for preparing an amino acid (e.g., iminodiacetic acid) from a salt of the amino acid (e.g., disodium iminodiacetic acid) utilizing a two-compartment bipolar membrane electrodialysis process wherein at least a portion of the salt product stream comprising the amino acid and one or more salt thereof is recirculated to the two-compartment bipolar membrane. The process also comprises removing at least a portion of the recirculation stream and phosphonomethylating the amino acid therein. The process further comprises recovering a base product stream and utilizing the base product stream for preparing the salt of the amino acid.

A method for synthesis of N-phosphonoalkyliminodiacetic acid or derivatives thereof by forming a reaction mixture having an acid catalyst, a compound of the following general formula R.sup.1CH.sub.2NXCH.sub.2R.sup.2 and a compound having one or more POP anhydride moieties to form a compound having a formula R.sup.1CH.sub.2N(CH.sub.2PO.sub.3R.sup.3.sub.2)(CH.sub.2R.sup.2) wherein in R.sup.1CH.sub.2NXCH.sub.2R.sup.2: X is CH.sub.2OH or CH.sub.2COOH; R.sup.1 and R.sup.2 are independently selected from the group consisting of nitrile, C.sub.1-C.sub.4 alkyl carboxylate, and carboxylic acid for when X is CH.sub.2OH, or R.sup.1 and R.sup.2 are both carbonyl groups linked by a hydrogen substituted nitrogen atom or a C.sub.1-C.sub.4-alkyl substituted nitrogen atom; and R.sup.3 is H, an alkyl group, or an aryl group; the anhydride moieties in the POP anhydride compound have one P atom at the oxidation state (+III) and one P atom at the oxidation state (+III) or (+V); and 2) hydrolyzing the mixture to form N-phosphonomethyliminodiacetic acid or one of its derivatives.

The present disclosure provides a method for removing a phosphorus compound from an aqueous medium. In one embodiment, the method includes: providing a rare-earth metal-modified carrier; and contacting the rare-earth metal-modified carrier with an aqueous medium including the phosphorus compound under conditions effective to remove at least a portion of the phosphorus compound from the aqueous medium.