C07K4/02

Identification and Attenuation of the Immunosuppressive Domains in Fusion Proteins of Enveloped RNA Viruses
20240150409 · 2024-05-09 ·

The present invention relates to enveloped RNA viruses. The invention in particular relates to the generation of superior antigens for mounting an immune response by first identifying then mutating the immunosuppressive domains in fusion proteins of enveloped RNA viruses resulting in decreased immunosuppressive properties of viral envelope proteins from the viruses.

ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS

Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm formation, or essential genes, and related compositions and methods of using the oligomers and compositions, for instance, in the treatment of an infected mammalian subject.

ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS

Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm formation, or essential genes, and related compositions and methods of using the oligomers and compositions, for instance, in the treatment of an infected mammalian subject.

Elimination of immune responses to viral vectors

The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from a viral vector antigen and a redox motif such as C-(X)2-[CST] or [CST]-(X)2-C in the prevention and/or suppression of immune responses to viral vectors and in the manufacture of medicaments therefore.

Elimination of immune responses to viral vectors

The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from a viral vector antigen and a redox motif such as C-(X)2-[CST] or [CST]-(X)2-C in the prevention and/or suppression of immune responses to viral vectors and in the manufacture of medicaments therefore.

VIRUS SCAFFOLD FOR SELF-ASSEMBLED, FLEXIBLE AND LIGHT LITHIUM BATTERY

A variety of compositions that include a metal oxide, films and batteries comprising one or more of the compositions, and methods of making the same.

VIRUS SCAFFOLD FOR SELF-ASSEMBLED, FLEXIBLE AND LIGHT LITHIUM BATTERY

A variety of compositions that include a metal oxide, films and batteries comprising one or more of the compositions, and methods of making the same.

Virus scaffold for self-assembled, flexible and light lithium battery

A variety of compositions that include a metal oxide, films and batteries comprising one or more of the compositions, and methods of making the same.

Virus scaffold for self-assembled, flexible and light lithium battery

A variety of compositions that include a metal oxide, films and batteries comprising one or more of the compositions, and methods of making the same.