Patent classifications
C09B23/166
Methods of using nucleotide analogues
The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
Near infrared absorbing dye, optical filter, and imaging device
A near infrared absorbing dye includes a croconium-based compound shown in formula (AI). In formula (AI), ring Z is either an optionally substituted 6-membered ring including no heteroatom or an optionally substituted 5-membered ring including 0 to 3 heteroatoms in the ring, R.sup.1 and R.sup.2, R.sup.2 and R.sup.3, and R.sup.1 and a carbon atom or heteroatom as a part of ring Z may be linked to each other to respectively form a heteroring A, a heteroring B, and a heteroring C together with a nitrogen atom. ##STR00001##
WAVELENGTH SELECTIVE ABSORPTION FILTER AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE
There are provided a wavelength selective absorption filter including a resin, and four types of dyes A to D each having a main absorption wavelength range in different specific wavelength regions, in which an absorbance Ab (λ) of the wavelength selective absorption filter at a wavelength λ nm satisfies specific Relational Expressions (I) to (VI), and an organic electroluminescent display device.
Organic salts for high voltage organic and transparent solar cells
Photo-active devices including a substrate, a first electrode, an active layer including an organic salt or salt mixture that selectively or predominantly harvests light from the near infrared or infrared regions of the solar spectrum, and a second electrode. The devices are either visibly transparent or visibly opaque and can be utilized in single- or multi-junction devices.
Methods for synthesizing nucleotide analogues with disulfide linkers
The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
Nucleotide analogues
The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
CA IX - NIR DYES AND THEIR USES
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
OPTICAL FILTER AND IMAGING DEVICE
The present invention relates to an optical filter containing: an absorption layer containing a near-infrared absorbing dye satisfying the following (i-1) to (i-5), and a transparent resin; and a reflection layer, and satisfying the following (ii-1); (i-1) .sub.max(A) TR is in a wavelength range of 760 to 900 nm; (i-2) T.sub.435-480ave (A) TR and T.sub.480-590ave (A) TR are both 90% or more. (i-3) .sub.max(A) DCM is in a wavelength range of 760 to 900 nm. (i-4) T.sub.435-480ave (A) DCM is 95% or more and T.sub.480-590ave (A) DCM is 97% or more. (i-5) a difference between T.sub.435-480ave (A) DCM and T.sub.435-480ave (A) TR, and a difference between T.sub.480-590ave (A) DCM and T.sub.480-590ave (A) TR are 10.5% or less. (ii-1) an average transmittance of light in the wavelength range of 800 to 900 nm is 5% or less at an incident angle of 60 degrees.
CA IX—NIR dyes and their uses
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
Highly fluorescent pyrrole-BF.SUB.2 .chromophores
Fluorescent chromophores nicknamed BOPHY are provided. The chromophores may be readily synthesized in two steps from readily available reagents via the coupling of a pyrrole aldehyde or ketone with hydrazine, followed by reaction with BF.sub.3. The resultant symmetric and dimeric tetracycle is comprised of two BF.sub.2 units in six-member chelate rings, appended by pyrrole units on the periphery. The quantum yield of fluorescence for the unmodified compound and the tetramethyl variant are near unity, with values 95 and 92% respectively in CH.sub.2Cl.sub.2.