An exemplary compounding system and method can include a transfer set that includes a manifold for assisting in transferring a plurality of ingredients from supply container(s) to a final container. The manifold can include a first channel in fluid communication with at least one primary ingredient, and a second channel in fluid communication with a plurality of secondary ingredients. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold. The transfer set can include a plurality of inlet lines in fluid communication with the manifold and two outlet lines configured for connection to two separate pumps and eventually being in fluid communication with the final container.

A fluid handling device includes: a substrate including a first surface and a second surface which are opposite to each other, wherein a first recess which allows fluid to flow therethrough is formed on the first surface; a film including a third surface and a fourth surface which are opposite to each other, wherein at least a pair of second recesses is formed on the third surface; and at least a pair of electrodes whose shape is defined by the second recesses, the electrodes being disposed in the second recesses and configured to apply an electric field to an inside of the first recess, the film being joined to the substrate such that the first surface and the fourth surface face each other.

In an example implementation, a method of controlling a microfluidic valve includes activating a first inertial pump at a first frequency, and a second inertial pump at a second frequency to create a first fluid flow pattern within a microfluidic valve. The method also includes adjusting at least one of the first frequency and the second frequency to change the first fluid flow pattern to a second fluid flow pattern.

An apparatus for controlling flow of ER fluid. The apparatus has a first channel 10 for conveying carrier fluid 1 of a first dielectric constant and droplets 2 of a second dielectric constant in the carrier fluid. The apparatus further comprises a second channel 20 conveying the ER fluid and a first conductor 100 for conveying an electrical potential from the second channel to the first channel. A circuit 61 is provided for applying potential difference between the first and second channels. When a droplet is present in the first channel, the ER fluid is solidified in the second channel; when no droplet is present, the ER fluid flows as liquid in the second channel. Therefore the apparatus acts as an IF gate. Arrangements for other types of fluidic logic gate are also disclosed.

A microchannel heat exchanger is configured for use as an evaporator in a fluid cooling system and includes an inlet header, an outlet header, and a plurality of microchannel tubes extending between and in fluid communication with the inlet header and the outlet header. A microvalve actuated hybrid spool valve is attached to and in fluid communication with the inlet header.

Disclosed is a system including a flow control assembly. The system may include a flow regulating shunt system, for various purposes. The flow control assembly may be controlled according to selected parameters and methods.

A fluidic system having a first volume, a second volume and a membrane geometrically separating the two volumes, which has an open-pore microstructure for the passage of a first medium and a second medium. There is a contact angle (Θ) between the interface of the media and the pore surface. A first electrical field in the region of the membrane and a first electromagnetic radiation and a first heating of the membrane define a first state (Z.sub.1), in which the membrane is not wetted or is less wetted by the first medium and is more heavily wetted by the second medium such that a first contact angle Θ.sub.1>90° is formed between the pore surface and the interface. The first medium and the second medium and the pore surface have a surface energy of which at least one surface energy can be reversibly changed in such a way that a second contact angle Θ.sub.2<Θ.sub.1 occurs between the pore surface and the interface in a second state (Z.sub.2).

Disclosed is a system including a flow control assembly. The system may include a flow regulating shunt system, for various purposes. The flow control assembly may be controlled according to selected parameters and methods.

Surface-modified glass and polymer membrane interfaces form high-electrical resistance seals that can be used in microfluidic valves and array devices tailored for electrophysiological measurements. The incorporation of high seal resistance valves into the array device allows only the desired electrophysiological signal to be detected by a patch clamp amplifier, enabling parallel experiments with one patch clamp amplifier, which can greatly improve the cost efficiency. To achieve the desired high seal resistance, surface modification was performed on the glass components to increase the interaction between the glass and the membrane surfaces. The valves exhibit seal resistance of >500 GΩ after modification, which is 100× higher than reported for unmodified valves.

The present invention generally relates to systems and methods for the control of fluids and, in some cases, to systems and methods for flowing a fluid into and/or out of other fluids. As examples, fluid may be injected into a droplet contained within a fluidic channel, or a fluid may be injected into a fluidic channel to create a droplet. In some embodiments, electrodes may be used to apply an electric field to one or more fluidic channels, e.g., proximate an intersection of at least two fluidic channels. For instance, a first fluid may be urged into and/or out of a second fluid, facilitated by the electric field. The electric field, in some cases, may disrupt an interface between a first fluid and at least one other fluid. Properties such as the volume, flow rate, etc. of a first fluid being urged into and/or out of a second fluid can be controlled by controlling various properties of the fluid and/or a fluidic droplet, for example curvature of the fluidic droplet, and/or controlling the applied electric field.