The present technology provides methods, systems, and apparatuses to achieve high throughput and high speed acquisition of partial wave spectroscopic (PWS) microscopic images. In particular, provided herein are high-throughput, automated partial wave spectroscopy (HT/A-PWS) instruments and systems capable of rapid acquisition of PWS Microscopic images and clinical, diagnostic, and research applications thereof.

A light emitting structure for a photo-acoustic spectroscopy sensing device for sensing a target gas comprises a light source configured for emitting light of an input wavelength. The light emitting structure further comprises a conversion structure that is configured for absorbing light of the input wavelength, and that is further configured for emitting light of an output wavelength. The output wavelength of the conversion structure is adapted to an absorption wavelength of the target gas. The conversion structure comprises an output conversion layer that comprises a plurality of nanoparticles. The nanoparticles of the output conversion layer are configured for emitting light of the output wavelength.

Tunable filters can use Fano metasurface designs having extremely narrow transmission bands. The Fano metasurface can comprise dielectric or semiconductor materials and can produce transmission bands with quality factors well in excess of 1000—at least a factor of 50 greater than typical metamaterial-based infrared resonances. Numerical simulations of these metasurfaces show that the spectral position of the passband can be changed by slightly changing the position of a small dielectric perturbation block placed within the near-field of the resonator by using simple electromechanical actuation architectures that allow for such motion. An array of independently tunable narrowband infrared filters can thereby be fabricated that only requires deep-subwavelength motions of perturbing objects in the resonator's near-field.

A system and method for analyzing a sample using Raman spectral light includes a light source, a light detector, a narrow band pass filter and an analyzer. Within the system, excitation light is directed to interrogate the sample. The narrow band pass filter is positioned to receive Raman scattered light produced as a result of the interrogation. The light detector is positioned to receive the Raman scattered light that has passed through the at least one narrow band pass filter. The analyzer contains stored instructions that when executed cause the processor to a) control the light source; and b) process signals produced by the light detector to analyze the sample material, the signals representative of the intensity of the Raman scattered light received by the at least one light detector corresponding to one or more wavenumbers in a high wavenumber region of a Raman signal.

An apparatus and a method measure a reflectivity and/or transmittivity of an optical surface. The apparatus includes a pulsed coherent white light source for generating pulsed coherent white light, wherein the apparatus is adapted to irradiate the optical surface with at least a part of the generated pulsed coherent white light.

An analyte detection apparatus, includes a radiation source for irradiating a sample; a receiver, to receive an optical Raman spectrum of radiation transmitted back from the sample in response to the received radiation from the source, wherein the receiver includes a plurality of different types of analysis device each arranged to receive a selected part of the received optical spectrum transmitted back from the sample.

An illumination and detection apparatus for a metrology tool, and associated method. The apparatus includes an illumination arrangement operable to produce measurement illumination having a plurality of discrete wavelength bands and having a spectrum having no more than a single peak within each wavelength band. The detection arrangement includes a detection beamsplitter to split scattered radiation into a plurality of channels, each channel corresponding to a different one of the wavelength bands; and at least one detector for separate detection of each channel.

A method and device of plant spectropolarimetric imaging is disclosed. A device comprising a first illuminator to direct light toward at least a portion of a plant with epi-illumination, a second illuminator to direct light toward at least a portion of a plant with transillumination, wherein the first and second illuminators are broadband, covering visible and infrared spectra; an imaging system to form images; a detection system to record the images, wherein the detection system measures in a plurality of spectral channels; and a computer to display and analyze the recorded images from the detection system. The detection system or the imaging system, comprises a polarization analyzer system. A method comprising directing light from at least one broadband illuminator toward at least a portion of a plant; forming images with an imaging system; recording the images with a detection system; and analyzing the recorded images with a computer.

The invention relates to a device and corresponding method for raster-scan optoacoustic imaging, the device comprising: a radiation source comprising at least one Raman laser source, the radiation source being configured to generate a plurality of pulses of electromagnetic radiation, each of the pulses comprising portions of electromagnetic radiation at two or more distinct wavelengths, and at least one acousto-optic tunable filter configured to select, from at least one of the pulses, one of the portions of electromagnetic radiation at one of the wavelengths; an irradiation unit configured to irradiate a region of interest of an object, in particular a biological tissue, with the selected portion of electromagnetic radiation of the at least one pulse; a detection unit configured to detect acoustic waves emitted from the region of interest in response to irradiating the region of interest with the selected portion of electromagnetic radiation of the at least one pulse; and a scanning unit configured to move the irradiation unit and detection unit, on the one hand, and/or the region of interest, on the other hand, along at least one dimension relative to each other so as to position the irradiation unit and detection unit at a plurality of different locations along the at least one dimension relative to the region of interest, and to control the detection unit to detect the acoustic waves at the plurality of locations.

A light emitting structure for a photo-acoustic spectroscopy sensing device for sensing a target gas comprises a light source configured for emitting light of an input wavelength. The light emitting structure further comprises a conversion structure that is configured for absorbing light of the input wavelength, and that is further configured for emitting light of an output wavelength. The output wavelength of the conversion structure is adapted to an absorption wavelength of the target gas. The conversion structure comprises an output conversion layer that comprises a plurality of nanoparticles. The nanoparticles of the output conversion layer are configured for emitting light of the output wavelength.