Embodiments herein relate to reflective optical medical sensor devices. In an embodiment, a reflective optical medical sensor device including a central optical detector and a plurality of light emitter units disposed around the central optical detector is provided. A plurality of peripheral optical detectors can be disposed to the outside of the plurality of light emitter units. Each of the plurality of peripheral optical detectors can form a channel pair with one of the plurality of light emitter units. The reflective optical medical sensor device can also include a controller in electrical communication with the central optical detector, the light emitter units, and the peripheral optical detectors. The controller can be configured to measure performance of channel pairs; select a particular channel pair; and measure a physiological parameter using the selected channel pair. Other embodiments are also included herein.

Systems and methods are provided for measuring the mechanical properties of ocular tissue, such as the lens or corneal tissue, for diagnosis as well as treatment monitoring purposes. A laser locking feedback system is provided to achieve frequency accuracy and sensitivity that facilitates operations and diagnosis with great sensitivity and accuracy. Differential comparisons between eye tissue regions of a patient, either on the same eye or a fellow eye, can further facilitate early diagnosis and monitoring.

The present disclosure provides a scanning probe, a method and an apparatus for manufacturing the scanning probe. The scanning probe includes a base and a micro-tip disposed on an end of the base, wherein at least a section of the micro-tip comprises a lateral surface with a concavely curved generatrix. In the method, an end of a probe precursor is immersed in a corrosive solution by having a length direction of the probe precursor inclined with a liquid surface of the corrosive solution. The probe precursor is corroded by the corrosive solution while a corrosion current of the corroding is monitored. The probe precursor is moved away from the corrosive solution after a magnitude of the corrosion current has a plunge. The apparatus includes a container containing the corrosive solution, and a driving device configured to move the probe precursor in the container through a fastener.

A compact, catadioptric and athermal imaging spectrometer is disclosed. A telecentric light (1) incident from a slit (2) is folded or refracted by an object-side prism (3) to enter a plano-convex lens (4); after being refracted by the plano-convex lens (4) and a meniscus lens (5), and refracted and reflected by a thick catadioptric lens (6), said telecentric light is incident onto a convex grating (7) in the form of a convergent beam; and after said beam is diffracted, spectral division is implemented. The divergent beam is sequentially refracted and reflected by the thick catadioptric lens (6), and refracted by the meniscus lens (5) and the plano-convex lens (4) to enter an image-side prism (8). Said beam is folded or refracted and filtered, and imaged on a focal plane (10) to realize spectral imaging.

A Raman spectrometer 1 comprising a laser 1001 for illuminating a sample S under investigation, an auto-focusing system for focusing the laser 1001 on the sample S under investigation, and a detector 1010 for detecting Raman spectra emitted in response to illumination by the laser 1001. The auto-focusing system further comprises at least one adjustable focusing element for adjusting the location of the focus of the laser, a determination unit 1012 for determining a selected location for the focus of the laser 1001, and a control unit for adjusting the adjustable focusing element to focus the laser at said selected location determined by the determination unit 1012. The auto-focusing system is arranged under the control of software to enable determination of the selected location for the focus of the laser 1001.

A system and method using remote sensing instrument with hyper spectrum quantitatively measure metal dust elements in lubricating oil, which includes (no limited): Al, Cd, Cr, Cu, Fe, Pb, Mg, Mn, Mo, Ni, Ag, Sn, Ti, V, Zn, B (Boron, for Coolant), Ca (Calcium for water contaminant), and particle size, cone penetration, dropping point, steel mesh oil separation, moisture, PQ concentration, in few seconds. The instrument integrates near-field communication (NFC), Internet of Thing (IoT), Cloud computing, spectral matching and other data processing, and application software forming a system to easily operated and build a model enable self-learning to improve precision through collection accumulation. With the system, the instrument as FIG. 1 can provide comprehensive on-site analysis enable preventive maintenance of mission critical engine and rotating equipment. The characteristics of the system are easy to operate, get result quickly, and self-learning to improve precision.

Exemplary methods for detecting presence of water in a sample include: heating a light source to a predetermined temperature at which the light source emits thermal radiation; placing a sample between the light source and a detector; transmitting the thermal radiation from the light source through the sample and onto the detector; and determining a presence or an absence of water within the sample based on the thermal radiation transmitted onto the detector. Exemplary systems for detecting presence of water in a sample are also disclosed.

Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors. MIR-PHI experiments are shown that achieve high sensitivity, sub-diffraction limit spatial resolution, and high acquisition speed. Sensitive, affordable, and widely applicable, photothermal imaging techniques described herein can serve as a useful imaging tool for biological systems and other submicron-scale applications.

A processing apparatus combines a plurality of images based on a plurality of object images formed on an imaging plane of an image sensor by a plurality of lens units and to generate a combined image, and includes at least one processor or circuit that serves as an acquisition task configured to acquire information on a center position of each of the plurality of object images on the imaging plane, information on a correspondence relationship between the center position and positions of the plurality of images in the combined image, and conversion information for converting a first coordinate system in the imaging plane into a second coordinate system in the combined image, the conversion information being generated based on a correction function for correcting the plurality of object images, and a processing task configured to generate the combined image using the conversion information.

A method and apparatus for simulating spectral representation of a region of interest is disclosed. In one embodiment, the method comprises determining a physical characteristic of a geospatial portion of the region of interest, associating the determined physical characteristic with a material of a spectral library, the spectral library having at least one spectral definition material, associating the spectral definition of the material with the geospatial portion of the region of interest, wherein the material is at least partially representative of the geospatial section of the region of interest, and generating the simulated spectral representation of the region of interest at least in part from at least the associated spectral definition of the at least one material.