Patent classifications
G01N2015/003
Systems and methods for detecting particles in a fluid channel
Disclosed herein are systems and methods capable of identifying, tracking, and sorting particles or droplets flowing in a channel, for example, a microfluidic channel having a fluid medium. The channel and the fluid medium can have a similar refractive index such that they appear translucent or transparent when illuminated by electromagnetic radiation. The particles or droplets can have a refractive index substantially different from that of the channel and the medium, such that the particles or droplets interfere with the electromagnetic radiation. A sensor can be disposed adjacent to the channel to record the electromagnetic radiation. The sensor can be attached to a system for identifying, tracking, and sorting the droplets.
Methods for sorting particles
Methods and systems for sorting particles are provided. Methods and systems for sorting cell beads are provided. In some cases, cell beads may be sorted from particles unoccupied with cell derivatives. In some cases, singularly occupied cell beads may be sorted from unoccupied particles and multiply occupied cell beads.
METHOD FOR ANALYZING AND SELECTING A SPECIFIC DROPLET AMONG A PLURALITY OF DROPLETS AND ASSOCIATED APPARATUS
The present invention relates to a method for analyzing and selecting a specific droplet among a plurality of droplets (4), comprising the following steps: —providing a plurality of droplets (4), —for a droplet (4) among the plurality of droplets, measuring at least two optical signals, each optical signal being representative of a light intensity spatial distribution in the droplet for an associated wavelength channel, —calculating a plurality of parameters from the optical signals, —determining a sorting class for a droplet according to calculated parameters, —sorting said droplet according to its sorting class, wherein the plurality of parameters comprises the coordinates of a maximum for each optical signal and a co-localization parameter and the at least two calculated parameters used for the determining step comprises the co-localization parameter.
Handling obstructions and transmission element contamination for self-mixing particulate matter sensors
A portable electronic device is operable in a particulate matter concentration mode where the portable electronic device uses a self-mixing interferometry sensor to emit a beam of coherent light from an optical resonant cavity, receive a reflection or backscatter of the beam into the optical resonant cavity, produce a self-mixing signal resulting from a reflection or backscatter of the beam of coherent light, and determine a particle velocity and/or particulate matter concentration using the self-mixing signal. The portable electronic device is also operable in an absolute distance mode where the portable electronic device determines whether or not an absolute distance determined using the self-mixing signal is outside or within a particulate sensing volume associated with the beam of coherent light. If not, the portable electronic device may determine a contamination and/or obstruction is present that may result in inaccurate particle velocity and/or particulate matter concentration determination.
METHOD AND SYSTEM FOR RECOVERING PRODUCTS FROM AN EMULSION
The present invention relates to a method for selecting and recovering products, including providing an emulsion (6) comprising a plurality of drops (4) contained in a carrier fluid (10), each drop comprising an internal fluid (8), measuring at least one physical parameter for several drops (4) of the emulsion (6), classifying at least some of the drops (4) of the emulsion in a class based on measurements obtained during measuring, tagging at least some of the classified drops (4) based on the class of the drop (4), and selectively recovering the drop (4) or part of the drop (4) using the tag of the drop or part of the drop (4).
ULTRASONIC CONTAMINANT DETECTION SYSTEM
The invention generally provides a system and method for detecting, measuring, and/or classifying particulate and/or water contaminants in a fluid supply line, storage tank, or sump. Embodiments of the invention provide a contaminant detection apparatus with a detection chamber and a detection module. The detection chamber includes a housing with an internal fluid conduit and one or more acoustic transducers disposed in the housing. Alarms and/or automatic signaling may be included to shut off valves or pumps when contaminants are detected.
METHOD OF ANALYZING THE CONTENT OF DROPS AND ASSOCIATED APPARATUS
The invention concerns a method of analyzing the content of drops, involving then following step: providing a plurality of drops (6) contained in a carrier fluid, at least one of the drops (6) comprising at least one aggregate (10) of particles defining an object extending along a main axis, at least some of the drops (6) containing at least one target element capable of attaching to the aggregate (10).
The method involves a step in which a physical parameter characteristic of the attachment of the target element to the aggregate (10) is measured.
SYSTEM AND METHOD FOR MEASURING OIL CONTENT IN WATER USING LASER-INDUCED FLUORESCENT IMAGING
The invention is a system and method to measure oil content in water utilizing the fluorescence of oil emitted under excitation by laser. Oil and water mixture is transferred through the system to a measurement section in a microscope, which produces high resolution 3-dimensional images of the oil and water mixture with the fluorescence. The images are analyzed to calculate the amount of oil in water and oil droplets distribution. The image is also analyzed to distinguish oil coated solids from oil droplets, and to calculate the sizes and volumes of the solids.
Microfluidic dielectrophoretic droplet extraction
A microfluidic apparatus for separating a droplet of an emulsion in a microfluidic environment is described. The microfluidic apparatus includes a flow cell comprising a first microfluidic channel configured for flowing a first fluid through the flow cell and a second microfluidic channel configured for flowing a stream of a second fluid through the flow cell. The microfluidic apparatus further comprises a first electrode positioned at the first microfluidic channel and a second electrode positioned at the second microfluidic channel on an opposite side of the interface with respect to the first electrode. The first electrode, the second electrode, and the first and second microfluidic channels are configured to generate a non-uniform electric field gradient in the microfluidic apparatus.
System And Method For Characterizing Particulates in a Fluid Sample
A system for characterizing at least one particle from a fluid sample is disclosed. The system includes a filter disposed upstream of an outlet, and a luminaire configured to illuminate the at least one particle at an oblique angle. An imaging device is configured to capture and process images of the illuminated at least one particle as it rests on the filter for characterizing the at least one particle. A system for characterizing at least one particle using bright field illumination is also disclosed. A method for characterizing particulates in a fluid sample using at least one of oblique angle and bright field illumination is also disclosed.