The present specification discloses natural repellent compounds, and isomeric forms, structural analogues and derivatives of the said compounds, having repellent activity against mosquitoes and other blood-sucking arthropods, compositions comprising such repellent compounds, methods of screening for such repellent compounds, methods of reducing mosquito bites on an individual and methods of reducing mosquito infestation to a location.

This invention concerns a product comprising one or more purinergic receptor (PR) antagonist for use in prevention and/or treatment of parasitic infestation of a human and/or animal host by an arthropod parasite by exposing the arthropod parasite to one or more PR antagonist, or by contacting the arthropod parasite with one or more PR antagonist. The invention also concerns a pharmaceutical composition comprising the product for use in prevention and/or treatment of parasitic infestation of a human and/or animal host by an arthropod parasite, and screening methods to identify suitable PR antagonist.

The present specification discloses natural repellent compounds, and isomeric forms, structural analogs and derivatives of the said compounds, having repellent activity against mosquitoes and other blood-sucking arthropods, compositions comprising such repellent compounds, methods of screening for such repellent compounds, methods of reducing mosquito bites on an individual and methods of reducing mosquito infestation to a location.

An apparatus includes a portable housing with a cavity, a heater disposed within the cavity of the housing, a temperature buffering device coupled to the heater and disposed within the cavity of the housing, a non-biological skin substitute substrate coupled to the temperature buffering device and disposed within the cavity of the housing, and a carbon dioxide delivery device coupled to the housing. The non-biological skin substrate simulates a surface property of human skin.

Described herein are compositions and methods useful for isolating compositions that repel insects, including mosquitoes.