The invention pertains to advances in real-time methods in nuclear magnetic resonance, magnetic resonance imaging, and non-invasive medical ablation by offering: a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations, a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability, a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region, a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter, a new real-time processing method for visualizing, targeting, and guiding surgical and other non-invasive processes, and a new method of non-invasive ablation, heat generation, and chemical reaction activation inside the human body to support a fully automatic or semi-automatic surgical procedure without the use of invasive devices, thus providing material reduction in risk to patient safety.

A method and a device for detecting substances and their concentrations in a mixture using magnetic resonance, containing one or more markers deposited on a surface of a carrier in contact with the mixture, wherein the marker is a substance that through intermolecular interactions causes a predetermined orientation of molecules for at least one of the mixture components.

The invention pertains to advances in constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region.

The invention pertains to advances in constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region.

The invention teaches a method proposing two new indices for evaluating thermal evolution in oils from different basins and organofacies. The first index is based on the distribution ratio of high molecular weight sulfur compounds, belonging to the DBE 6 (benzothiophene) and DBE 9 (dibenzothiophene) series. The second index, called TEI, was created from the profile of aromatic hydrocarbons and molecules containing N, O and S. Both parameters were obtained from the direct characterization of the oils, by using the photoionization at atmospheric pressure (APPI) technique combined with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS).

The invention teaches a method proposing two new indices for evaluating thermal evolution in oils from different basins and organofacies. The first index is based on the distribution ratio of high molecular weight sulfur compounds, belonging to the DBE 6 (benzothiophene) and DBE 9 (dibenzothiophene) series. The second index, called TEI, was created from the profile of aromatic hydrocarbons and molecules containing N, O and S. Both parameters were obtained from the direct characterization of the oils, by using the photoionization at atmospheric pressure (APPI) technique combined with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS).

The invention pertains to advances in real-time methods in nuclear magnetic resonance, magnetic resonance imaging, and non-invasive medical ablation by offering: a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations, a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability, a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region, a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter, a new real-time processing method for visualizing, targeting, and guiding surgical and other non-invasive processes, and a new method of non-invasive ablation, heat generation, and chemical reaction activation inside the human body to support a fully automatic or semi-automatic surgical procedure without the use of invasive devices, thus providing material reduction in risk to patient safety.

The invention pertains to advances in constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region.

The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering: a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations, a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability, a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region, a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter.

The present disclosure relates to methods and apparatus for identifying metabolic pathways and metabolites in complex biological samples. In particular, the present disclosure relates to a method and apparatus to increase the confidence of metabolite identification in metabolomics, such as in untargeted metabolomics data, using various statistical tools, such as over representation and enrichment analysis.