Data acquired from a scan of an object can be decomposed into frequency components. The frequency components can be input into a trained model to obtain processed frequency components. These processed frequency components can be composed and used to generate a final image. The trained model can be trained, independently or dependently, using frequency components covering the same frequencies as the to-be-processed frequency components. In addition, organ specific processing can be enabled by training the trained model using image and/or projection datasets of the specific organ.

Dual-energy absorptiometry is used to estimate intramuscular adipose tissue metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing intramuscular adipose tissue as well as subcutaneous adipose tissue, at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the intramuscular adipose tissue in the slice, and using the resulting estimates. Processing the measurements includes an algorithm which places boundaries of regions, e.g., a large region and a smaller region. The regions are combined in an equation that is highly correlated with intramuscular adipose tissue measured by quantitative computed tomography in order to estimate intramuscular adipose tissue.

The invention refers to an apparatus (110) for generating an augmented image comprising a) a base image providing unit (111), wherein the base image is generated based on a combination of spectral image data, b) a contrast image providing unit (112), wherein the contrast image is generated based on a different combination of the spectral image data, c) a degree of saliency determination unit (113), wherein the degree of saliency is indicative of a difference between an image value of a voxel of the contrast image and an image value of a corresponding voxel of a predetermined template image, and d) an augmented image generation unit (114) for generating an augmented base image of the object by augmenting voxels of the base image based on the degree of saliency. The invention allows to provide the augmented base image with an improved image quality and information content.

An imaging system (100) includes an anti-correlated noise filter (120), which jointly filters noise from a first portion (116) and a second portion (118), and the first portion (116) and the second portion (118) include anti-correlated noise.

An image processing system (IPS) and related method to transform different multi-modal or multi-contrast input images (u,v) into respective transformed images (U, V). The transformation may proceed iteratively to improve a regularized objective function. The regularization is via a regularizer function (R). The regularizer function (R) is computed from noise normalized gradients of the two or more transformed images (u,v).

A method for determining at least one three-dimensional image data record of a target area from two sets of projection images recorded with x-ray spectra using different energy maxima. A first set of projection images is recorded via a first X-ray spectrum and different first projection directions and a second set of projection images via a second X-ray spectrum and different second projection directions which differ at least partially from the first projection directions. A three-dimensional anatomy image data record is reconstructed from the first and the second projection images. A three-dimensional spectral image data record is reconstructed by a weighted combination of a first three-dimensional reconstruction image data record reconstructed from the first projection images, and a second three-dimensional reconstruction image data record reconstructed from the second projection images. The anatomy image data record and the spectral image data record are displayed.

An apparatus, system and method for calibrating an x-ray apparatus including acquiring sinogram data by scanning a symmetrical phantom using a plurality of detector channels; generating mirror-copied sinogram data by mirror-copying at least one of first sinogram data and second sinogram data of the acquired sinogram data, wherein the first sinogram data and the second sinogram data are generated by dividing the sinogram data at a center detector channel of the plurality of detector channels; outputting a first reconstructed image by reconstructing the mirror-copied sinogram data; and determining a calibration parameter based on the first reconstructed image.

A calibration method for an x-ray computerized tomography system and a method of tomographic reconstruction are provided. The calibration method includes steps of measuring at least one point spread function (PSF) at each of a plurality of points, compressing each PSF, and in one or more storing operations, storing the compressed PSFs in a computer-accessible storage medium. The PSF measurements are made in a grid of calibration points in a field of view (FOV) of the system. In the measuring step, an absorber is positioned at each of the calibration points, and an x-ray projection is taken at least once at each of those absorber positions. In the method of tomographic image reconstruction, projection data from an x-ray tomographic projection system are input to an iterative image reconstruction algorithm. The algorithm retrieves and utilizes a priori system information (APSI) The APSI comprises comprising point spread functions (PSFs) of all voxels in a voxelization of the field of view that are compressed in the form of vectors of parameters. For utilization, each retrieved vector of parameters is decompressed so as to generate a discretized PSF.

A method and related apparatus (VS) for synthesizing a projection image (S), in particular for use in mammography. It is proposed to compute a weight function from one image volume (V1) and is then used to implement a weighted forward projection through another image volume block to compute a synthesized projection image (S) across block (V2).

A system and method for performing image processing. The method includes receiving an image of a first modality and a real image of a second modality, the image of the first modality and the image of the second modality capturing respective images of a same subject, applying a first trained model to the image of the first modality to generate an artificial image mimicking the image of the second modality, applying a second trained model to the artificial image mimicking the image of the second modality and data of the image of the first modality, and outputting at least one conclusion regarding the generated artificial image.