Independent control loops for mitigating positive and negative mismatch in differential amplifiers are provided. A method includes comparing a first voltage measured at a positive side output of an emitter follower with a reference voltage, resulting in a first voltage difference. The method also includes comparing a second voltage measured at a negative-side output of the emitter follower with the reference voltage, resulting in a second voltage difference. In addition, the method includes independently controlling the positive side and the negative side of the differential amplifier based on the first voltage difference and the second voltage difference.