This system takes in raw cellular material collected using a provided swab, blood collection device, urine collection device, or other sample collection device and transforms that biological material into a digital result, identifying the presence, absence and/or quantity of nucleic acids, proteins, and/or other molecules of interest.

An end fitting for use in connecting a gas source in fluid communication to an appliance, includes a nut mounted by a fusible and meltable heat activatable material on a socket having a chamber for receiving a plug. The plug connects to the gas source and the socket connects to the appliance. An O-ring of meltable heat activatable material separates the plug and socket. The socket includes a spring that biases a valve member against the plug and between closed and open conditions, respectively, to block or permit fluid flow from a source and through the chamber. In case of excess heat buildup in the socket body, the heat activatable materials melt but unless the gas source is turned off always allow a predetermined amount of gas to flow.

Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

The invention relates to a fusible link (100) for installation in a through-opening (4) in a gas tank (1000), having a tension rod (1), a guide sleeve (2) with at least one fluid-guiding duct (2a) for guiding gas out of the gas tank (1000) into the environment of the gas tank (1000), and a fusible sheath (3), wherein the guide sleeve (2) is formed in a ring around the tension rod (1) at least in some sections, and the fusible sheath (3) surrounds the guide sleeve (2) in a sheath-like manner at least in some sections, wherein the tension rod (10) has a tapered section (1a) which tapers in a direction away from the gas tank (1000) when installed in the gas tank (1000), the guide sleeve (2) has at least one predetermined breaking section (2b) which, when the fusible link (100) is installed into the through-opening (4), breaks to introduce fusible material (3a) into the at least one fluid-guiding duct (2a), as a result of which fused material (3a) from the fusible sheath (3) can pass into at least some sections of the at least one fluid-guiding duct (2a) to block a gas flow through the at least one fluid-guiding duct (2a), and the tension rod (1) and the guide sleeve (2) have a higher strength and/or temperature resistance than the fused material (3a). The invention also relates to a method for assembling a fusible link (100) and for installing same in a gas tank (1000).

Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

A pressurization device for pressurizing an enclosure may include a container containing a pressurized fluid, a pin that is inserted into the container, an actuator, and a heating device operably coupled to the actuator. The actuator may initially hold the pin in a closed position and allow the pin to move to an open position, disengaging from the container when the actuator increases in temperature. The pressurized fluid may force the pin toward the open position to release the pressurized fluid from the container. The actuator may include a frangible hollow bulb configured to fracture at a pre-defined temperature. The pressurized fluid may be vented into the enclosure through at least one fluid passage in fluid communication between the enclosure and the container.

A pressurization device for pressurizing an enclosure may include a container containing a pressurized fluid, a pin that is inserted into the container, an actuator, and a heating device operably coupled to the actuator. The actuator may initially hold the pin in a closed position and allow the pin to move to an open position, disengaging from the container when the actuator increases in temperature. The pressurized fluid may force the pin toward the open position to release the pressurized fluid from the container. The actuator may include a frangible hollow bulb configured to fracture at a pre-defined temperature. The pressurized fluid may be vented into the enclosure through at least one fluid passage in fluid communication between the enclosure and the container.

Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

A high temperature warning system for a vehicle steer axle an air pressure supply, a normally-closed valve in fluid communication with pressure supply, a heat sensitive control capable of opening the normally-closed valve upon a predetermined temperature, the heat sensitive control mounted adjacent to the wheel end assembly in a heat exchange relationship therewith, and a warning system connected to the air pressure supply for actuation upon opening of the normally-closed valve.