USE OF 4-(3-ETHOXY-4-HYDROXYPHENYL)ALKYLKETONE AS A SKIN-SOOTHING AGENT

Abstract

The present invention relates to the non-therapeutic cosmetic use of derivatives of 4-(3-ethoxy-4-hydroxyphenyl)alkyl ketone of formula (I)

##STR00001##

in which: R1 represents a C1-C4 alkyl radical; R2 represents a hydrogen atom, or a saturated or unsaturated, linear or branched C1-C6 hydrocarbon-based radical; R3 represents a saturated or unsaturated, linear or branched C1-C4 hydrocarbon-based radical optionally substituted by a hydroxyl group; C—X represents C═O or CH—OH; as agent for soothing the skin of the face and/or body.

Claims

1. (canceled)

2. (canceled)

3. (canceled)

4. (canceled)

5. (canceled)

6. (canceled)

7. (canceled)

8. (canceled)

9. (canceled)

10. (canceled)

11. A non-therapeutic cosmetic process for soothing the skin of the face and/or body, characterized in that it comprises the application, to the skin of the face and/or body, of a compound of formula (I) below: ##STR00008## in which: R1 represents a C1-C4 alkyl radical; R2 represents a hydrogen atom, or a saturated or unsaturated, linear or branched C1-C6 hydrocarbon-based radical; R3 represents a saturated or unsaturated, linear or branched C1-C4 hydrocarbon-based radical optionally substituted by a hydroxyl group; C—X represents C═O or CH—OH.

12. The process as claimed in claim 11, for preventing and/or treating unattractive non-pathological reactions and/or skin discomfort.

13. The process as claimed in claim 11, for preventing and/or treating at least one non-pathological skin reaction chosen from the group consisting of redness, stinging or tautness sensations.

14. The process as claimed in claim 11, wherein the compound of formula (I) is contained in a cosmetic composition.

15. The process as claimed in claim 11, wherein the compound of formula (I) is present in a cosmetic composition in an amount ranging from 0.01% to 10% by weight relative to the total weight of the composition.

16. The process as claimed in claim 11, in which, for the compound of formula (I): R1 represents an ethyl alkyl radical; R2 represents a hydrogen atom; R3 represents a saturated or unsaturated, linear or branched C1-C4 hydrocarbon-based radical optionally substituted by a hydroxyl group; C—X represents C═O or CH—OH.

17. The process as claimed in claim 11, in which, for the compound of formula (I): R1 represents an ethyl alkyl radical; R2 represents a hydrogen atom; R3 represents a saturated linear C1-C3 hydrocarbon-based radical; C—X represents C═O.

18. The process as claimed in claim 11, in which the compound of formula (I) is chosen from: ##STR00009##

19. The process as claimed in claim 11, in which the compound (I) is: ##STR00010##

20. The process as claimed in claim 11, wherein the compound of formula (I) is present in a cosmetic composition in an amount ranging from 0.1% to 5% by weight relative to the total weight of the composition.

21. The process as claimed in claim 12, in which, for the compound of formula (I): R1 represents an ethyl alkyl radical; R2 represents a hydrogen atom; R3 represents a saturated or unsaturated, linear or branched C1-C4 hydrocarbon-based radical optionally substituted by a hydroxyl group; C—X represents C═O or CH—OH.

22. The process as claimed in claim 12, in which, for the compound of formula (I): R1 represents an ethyl alkyl radical; R2 represents a hydrogen atom; R3 represents a saturated linear C1-C3 hydrocarbon-based radical; C—X represents C═O.

23. The process as claimed in claim 12, in which the compound of formula (I) is chosen from: ##STR00011##

24. The process as claimed in claim 12, in which the compound (I) is: ##STR00012##

25. The process as claimed in claim 12, wherein the compound of formula (I) is present in a cosmetic composition in an amount ranging from 0.1% to 5% by weight relative to the total weight of the composition.

26. The process as claimed in claim 13, in which, for the compound of formula (I): R1 represents an ethyl alkyl radical; R2 represents a hydrogen atom; R3 represents a saturated or unsaturated, linear or branched C1-C4 hydrocarbon-based radical optionally substituted by a hydroxyl group; C—X represents C═O or CH—OH.

27. The process as claimed in claim 13, in which, for the compound of formula (I): R1 represents an ethyl alkyl radical; R2 represents a hydrogen atom; R3 represents a saturated linear C1-C3 hydrocarbon-based radical; C—X represents C═O.

28. The process as claimed in claim 13, in which the compound of formula (I) is chosen from: ##STR00013##

29. The process as claimed in claim 13, in which the compound (I) is: ##STR00014##

30. The process as claimed in claim 13, wherein the compound of formula (I) is present in a cosmetic composition in an amount ranging from 0.1% to 5% by weight relative to the total weight of the composition.

Description

EXAMPLE 1

[0049]

TABLE-US-00001 A cosmetic gel having the following composition was prepared: compound 0.1% [00005] crosslinked acrylic acid (Carbopol 941) 0.3% water q.s. 100%

[0050] The gel applied to the skin of a face shaved beforehand or legs with the hair removed beforehand makes it possible to soothe the skin following shaving or hair removal.

EXAMPLE 2

[0051] The soothing properties of the compound were evaluated:

##STR00006##

with the following protocol:

[0052] The following composition (composition A) was prepared:

TABLE-US-00002 Compound 1.6 g [00007] AMPS homopolymer 0.19 g Cyclohexasiloxane 5 g Dimethicone 10 cst 3.75 g Hydrogenated polyisobutylene 4 g (Parleam from NOF Corporation) Sodium hydroxide 0.12 g Propane-1,3-diol 5 g Carboxyvinyl polymer 0.3 g (Carbopol 980 polymer from Lubrizol) Acrylic acid/C.sub.10-C.sub.30 alkyl methacrylate crosslinked copolymer 0.11 g (Pemulen TR-2 Polymer from Lubrizol) Neutralized polyacrylamidomethylpropanesulfonic acid 0.2 partially neutralized with ammonia and highly crosslinked (Hostacerin AMPS ® from Clariant) Citric acid 0.08 g Water q.s. 100 g

[0053] A placebo composition (composition P) was also prepared, without the ketone composition, replacing the amount thereof with water.

[0054] A test panel with 10 men was conducted to evaluate composition A and with 9 men to evaluate composition P. The men on the panels have white skin.

[0055] Each subject applied the composition after shaving in the morning and also in the evening before going to bed, for 5 days.

[0056] A first evaluation or measurement was carried out on the first day 20 minutes after shaving, then a second evaluation or measurement was made on the 5th day 20 minutes after shaving, as described below.

[0057] Measurement of skin redness: Skin redness was measured with a chromameter (Konica Minolta CR-400, D65 Daylight mode) on the area of the face treated with the composition and the untreated area. The color was measured using the CIE L a b system and the value was graded (3 measurements carried out).

[0058] With composition A, a reduction in the redness of 4.1% was obtained, while with the placebo composition the reduction in redness is 1.4%.

[0059] Evaluation of the tautness sensation of skin dryness:

[0060] The panel was also asked to evaluate the tautness sensation of skin dryness on the first day and on the fifth day of treatment, according to the following rating:

0=none
1=mild
2=moderate
3=severe

[0061] The mean grade awarded by the panel on the first and fifth day of treatment was then calculated, then the percentage difference was determined between the The following results were obtained:

Composition A:

[0062] Mean first day=0.90
Mean fifth day=0.30
i.e. a difference of 0.3/0.9×100=33.3%

Composition P:

[0063] Mean first day=0.78
Mean fifth day=0.44
i.e. a difference of 0.44/0.78×100=57.1%

[0064] The panel treated with composition A perceives a milder tautness sensation of skin dryness than that perceived by the panel treated with composition P.

[0065] The results obtained show that the ketone composition tested makes it possible to reduce skin redness and also the tautness sensation of skin dryness caused by shaving. The ketone composition therefore has a skin soothing action after shaving.