Intelligent Microbial Sample Treatment System
20220033760 · 2022-02-03
Assignee
Inventors
Cpc classification
B65G47/74
PERFORMING OPERATIONS; TRANSPORTING
C12M45/22
CHEMISTRY; METALLURGY
B65G29/00
PERFORMING OPERATIONS; TRANSPORTING
C12M45/02
CHEMISTRY; METALLURGY
C12M37/00
CHEMISTRY; METALLURGY
B67B3/20
PERFORMING OPERATIONS; TRANSPORTING
International classification
Abstract
An intelligent microbial sample treatment system includes a workbench, and a sample treatment assembly, a culture medium treatment assembly, a streaking assembly and a culture medium storage assembly that are disposed on the workbench; the sample treatment assembly comprises a sample transfer device, a filling device, and a scanning device, a weight detection device, a filling location, a shaking device and waiting locations that are disposed in sequence; and the sample transfer device moves a sample cup among the scanning device, the weight detection device, the filling location, the shaking device and the waiting locations. The intelligent microbial sample treatment system disclosed by the present invention enables improvement of work efficiency and reduction of space occupation and has a reasonable structural layout and high work efficiency.
Claims
1. An intelligent microbial sample treatment system, comprising a workbench, a sample treatment assembly, a culture medium treatment assembly, a streaking assembly and a culture medium storage assembly, wherein the sample treatment assembly, the culture medium treatment assembly, the streaking assembly and the culture medium storage assembly are disposed on the workbench; the sample treatment assembly comprises a sample transfer device, a filling device, and a scanning device, a weight detection device, a filling location, a shaking device and waiting locations disposed in sequence, and the sample transfer device moves a sample cup among the scanning device, the weight detection device, the filling location, the shaking device and the waiting locations; and the culture medium treatment assembly comprises a culture medium loading rotary table with loading grooves, a pushing device, an opening device and a culture medium streaking rotary table with station grooves, wherein the culture medium loading rotary table is located in front of the sample treatment assembly, the culture medium streaking rotary table is located beside the culture medium loading rotary table, and when the culture medium streaking rotary table rotates, the station grooves are sequentially close to the culture medium loading rotary table, the streaking assembly and the culture medium storage assembly.
2. The intelligent microbial sample treatment system of claim 1, wherein a number of the loading grooves is N and a number of the station grooves is n; the loading grooves are provided and distributed on the culture medium loading rotary table in a first annular array, and the station grooves are provided and distributed on the culture medium streaking rotary table in a second annular array; a station groove directly facing a loading groove is located at a loading station, and the pushing device is used for pushing a culture medium box in the loading groove into the station groove at the loading station; and the opening device is located at an upper portion of the station groove and used for opening the culture medium box entering the station groove.
3. The intelligent microbial sample treatment system of claim 2, wherein the loading groove is formed by a first side plate, a second side plate and a backing plate; the culture medium loading rotary table is provided with a positioning structure for positioning the first side plate, the second side plate and the backing plate, and the backing plate is provided with a penetrating hole for the pushing device to penetrate.
4. The intelligent microbial sample treatment system of claim 3, wherein the positioning structure comprises a plurality of positioning protrusions separately located between two adjacent loading grooves, wherein a first side of each of the positioning protrusions is provided with a first mounting groove for mounting the first side plate, a second side of each of the positioning protrusions is provided with a second mounting groove for mounting the second side plate, one end, close to a central axis of the culture medium loading rotary table, of each of the positioning protrusions is provided with a limiting blocking edge, one side, facing the central axis of the culture medium loading rotary table, of the backing plate is attached to the limiting blocking edge, and a gap for the pushing device to pass through is provided between two adjacent limiting blocking edges.
5. The intelligent microbial sample treatment system of claim 4, wherein one end, away from the central axis of the culture medium loading rotary table, of the loading groove is provided with a front plate, wherein a lower end of the front plate is pressed against one of the positioning protrusions, the front plate is provided with an elastic limiting plate extending into the loading groove, and a distance from a lower end of the elastic limiting plate to a bottom of the loading groove is less than a thickness of the culture medium box.
6. The intelligent microbial sample treatment system of claim 1, wherein the streaking assembly comprises a first-region streaking module, a second-region streaking module, a first placement seat located within a working range of the first-region streaking module and a second placement seat located within a working range of the second-region streaking module, the workbench is provided with a first driving structure, wherein a grabbing device is driven by the first driving structure and moves along an X axis and a Z axis, and a sterilizer located in a movement region of the grabbing device, the first placement seat is located in the movement region of the grabbing device, and the workbench is further provided with a second driving structure for driving the second placement seat to move between the working range of the second-region streaking module and the movement region of the grabbing device.
7. The intelligent microbial sample treatment system of claim 6, wherein the first driving structure comprises a support pillar disposed on the workbench, an X-axis guide rail disposed on the support pillar, a first sliding seat slidably disposed on the X-axis guide rail, a first power unit for driving the first sliding seat to slide, a Z-axis guide rail disposed on the first sliding seat, a second sliding seat slidably disposed on the Z-axis guide rail and a second power unit for driving the second sliding seat to slide, and the grabbing device is disposed on the second sliding seat.
8. The intelligent microbial sample treatment system of claim 7, wherein the second driving structure comprises a Y-axis guide rail disposed on the workbench, a third sliding seat disposed on the Y-axis guide rail and a third power unit for driving the third sliding seat to slide, a first end of the Y-axis guide rail is located in the movement region of the grabbing device, a second end of the Y-axis guide rail is located within the working range of the second-region streaking module, and the second placement seat is disposed on the third sliding seat.
9. The intelligent microbial sample treatment system of claim 1, wherein the culture medium storage assembly comprises a label printer, a culture medium storage box and a boxing module, a station groove disposed opposite to the label printer is located at a label printing station, the culture medium storage box is located between a streaking station and the label printing station and partially extends to a position above the culture medium streaking rotary table, the culture medium storage box is provided with a closing mechanism for closing a culture medium box moving to the label printing station from the streaking station, and the boxing module is used for moving the culture medium box between the label printing station and the culture medium storage box.
10. The intelligent microbial sample treatment system of claim 1, wherein the sample cup comprises a cup body and a cup cover, and an outer wall of the cup cover has a positioning plane vertically extending; the workbench is provided with a sample cup transmission device, the sample cup transmission device is provided with a sample input rail and an abnormal sample output rail, the sample input rail is provided with a guide door, an inner side of the guide door has a limiting plane vertically extending along a conveying direction of the sample input rail, and a minimum distance from a central axis of the cup cover of the sample cup located in the sample input rail to the limiting plane is equal to a distance from the positioning plane to the central axis of the cup cover.
11. The intelligent microbial sample treatment system of claim 1, wherein the sample cup comprises a cup body and a cup cover, a top of the cup cover has a plurality of grooves circumferentially distributed, the workbench is also provided with a sample cup opening and closing device, and the sample cup opening and closing device comprises a moving seat, a rotating body vertically disposed in a penetrating manner in the moving seat, and a power assembly for driving the rotating body to rotate around a central axis per se; and the sample cup opening and closing device further comprises one of the following structures: a first structure, wherein a plurality of protrusions which are circumferentially distributed at a bottom of the rotating body and are inserted into corresponding grooves in the plurality of grooves, a number of the plurality of grooves is larger than or equal to a number of the plurality of the protrusions, each of the plurality of protrusions having has one groove corresponding to each of the protrusions, and the rotating body is further provided with a grabbing assembly; and a second structure, wherein a clamping jaw is disposed at the bottom of the rotating body and is capable of implements opening and closing, the clamping jaw has a plurality of jaw portions circumferentially distributed and are inserted into the corresponding grooves, and the number of the corresponding grooves is a multiple of a number of the jaw portions.
12. The intelligent microbial sample treatment system of claim 11, wherein the grabbing assembly comprises a vacuum sucker disposed at the bottom of the rotating body and a pipeline structure communicating with the vacuum sucker and used for vacuum suction, and a bottom of the vacuum sucker is higher than a bottom of the protrusions.
13. The intelligent microbial sample treatment system of claim 12, wherein the pipeline structure comprises a passage vertically disposed in the rotating body, a first connector connected to an upper end of the passage and a second connector connected to a lower end of the passage, and the vacuum sucker communicates with the second connector.
14. The intelligent microbial sample treatment system of claim 13, wherein the bottom of the rotating body has a concave cavity communicating with the passage, and the vacuum sucker is disposed in the concave cavity.
15. The intelligent microbial sample treatment system of claim 13, wherein the vacuum sucker and the rotating body are coaxially disposed, and the passage and the rotating body are coaxially disposed.
16. The intelligent microbial sample treatment system of claim 12, wherein the moving seat has a mounting hole vertically disposed, the rotating body has a rotating shaft extending into the mounting hole, and a bearing located in the mounting hole is disposed between the rotating shaft and the moving seat.
17. The intelligent microbial sample treatment system of claim 16, wherein the power assembly comprises a motor disposed on the moving seat, a driving gear disposed on an output shaft of the motor and a driven gear disposed on the rotating shaft, and the driving gear is meshed with the driven gear.
18. The intelligent microbial sample treatment system of claim 14, wherein the vacuum sucker and the rotating body are coaxially disposed, and the passage and the rotating body are coaxially disposed.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
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[0046] In the drawings, 1, workbench; 2, sample transfer device; 3, filling device; 4, scanning device; 5, weight detection device; 6, filling location; 7, shaking device; 8, waiting location; 9, sample cup; 10, culture medium loading rotary table; 11, pushing device; 12, opening device; 13, culture medium streaking rotary table; 14, first side plate; 15, second side plate; 16, backing plate; 17, positioning protrusion; 18, first mounting groove; 19, second mounting groove; 20, limiting blocking edge; 21, gap; 22, front plate; 23, elastic limiting plate; 24, pressure plate; 25, screw; 26, first guide rail; 27, second guide rail; 28, first-region streaking module; 29, second-region streaking module; 30, first placement seat; 31, second placement seat; 32, grabbing device; 33, sterilizer; 34, support pillar; 35, X-axis guide rail; 36, first sliding seat; 37, first power unit, 38, Z-axis guide rail; 39, second sliding seat; 40, second power unit; 41, Y-axis guide rail; 42, third sliding seat; 43, needle seat; 431, counter weight block; 44, via hole; 45, inoculation needle body; 46, floating avoiding hole; 47, label printer; 48, culture medium storage box; 49, boxing module; 50, sample cup transmission device; 51, sample input rail; 52, abnormal sample output rail; 53, guide door; 54, moving seat; 55, rotating body; 56, protrusion; 57, vacuum sucker; 58, passage; 59, first connector; 60, second connector; 61, concave cavity; 62, mounting hole; 63, rotating shaft; 91, cup body; 92, cup cover; 93, positioning plane; and 94, groove.
DETAILED DESCRIPTION OF THE EMBODIMENTS
[0047] The followings are specific embodiments of the present invention and the technical solutions of the present invention will be further described in combination with the drawings, but the present invention is not limited to these embodiments.
Embodiment 1
[0048] As shown in
[0049] As shown in
[0050] In this embodiment, N (N≥2) loading grooves are provided and distributed on the culture medium loading rotary table 10 in an annular array, and n (n≥2) station grooves are provided and distributed on the culture medium streaking rotary table 13 in an annular array; the station groove directly facing the loading groove is located at a loading station, and the pushing device 11 is used for pushing a culture medium box in the loading groove into the station groove at the loading station; and the opening device 12 is located at the upper portion of the station groove and used for opening the culture medium box entering the station groove. The culture medium loading rotary table 10 carries out stepping rotation according to an angle of 360°/N, the culture medium streaking rotary table carries out stepping rotation according to an angle of 360°/n, and every time when the culture medium loading rotary table 10 and the culture medium streaking rotary table 13 rotate, there is one station groove directly facing the loading groove.
[0051] As shown in
[0052] As shown in
[0053] As shown in
[0054] As shown in
[0055] As shown in
[0056] When an inoculation needle in the first placement seat 30 is disinfected, the grabbing device 32 grabs the inoculation needle located in the first placement seat 30, the inoculation needle is enabled to move into the sterilizer 33 to be disinfected under the action of the first driving structure, and after disinfection is completed, the inoculation needle is returned to the first placement seat 30 under the action of the first driving structure and the grabbing device 32. When an inoculation needle in the second placement seat 31 is disinfected, the second driving structure drives the second placement seat 32 to move into the movement region of the grabbing device 32, the grabbing device 32 grabs the inoculation needle located in the second placement seat 31, the inoculation needle is enabled to move into the sterilizer 33 to be disinfected under the action of the first driving structure, after disinfection is completed, the inoculation needle is returned to the second placement seat 31 under the action of the first driving structure and the grabbing device 32, and subsequently the second placement seat 31 is returned to the working range of the second-region streaking module 29 under the action of the second driving structure.
[0057] As shown in
[0058] wherein, the first power unit 37 is a motor, and the motor is in transmission connection with the first sliding seat 36 by a first ball screw pair; and the second power unit 40 is a motor, and the motor is in transmission connection with the second sliding seat 39 by a second ball screw pair.
[0059] As shown in
[0060] wherein, the grabbing device 32 is an electromagnet, the inoculation needle grabbed by the grabbing device 32 comprises a needle seat 43, as shown in
[0061] As shown in
[0062] As shown in
[0063] After the cup body 91 is placed into the sample input rail 51, the cup body 91 cannot circumferentially rotate. When the sample cup 9 qualified in matching of the cup cover 92 and the cup body 91 passes through the guide door 53, the positioning plane 93 is parallel to the limiting plane without interference and obstruction therebetween, and the sample cup 9 can pass through the guide door 53; and when the sample cup 9 unqualified in matching of the cup cover 92 and the cup body 91 passes through the guide door 53, the positioning plane 93 is not parallel to the limiting plane, interference and obstruction can be generated therebetween, and the guide door 53 prevents the sample cup 9 from passing through.
[0064] As shown in
[0065] the sample cup opening and closing device further comprises the following structures:
[0066] a plurality of protrusions 56 which are circumferentially distributed at the bottom of the rotating body 55 and can be inserted into the corresponding grooves 94, the number of the grooves 94 being larger than or equal to that of the protrusions 56, each protrusion 56 having one groove 94 corresponding to the protrusion 56, and the rotating body 55 being further provided with a grabbing assembly.
[0067] A frame body is disposed on the workbench 1, and the moving seat 54 can be disposed on the frame body.
[0068] As shown in
[0069] As shown in
[0070] As shown in
[0071] As shown in
[0072] As shown in
[0073] The working steps of the intelligent microbial sample treatment system are as follows:
[0074] 1. the system is started, the sample box is manually/automatically placed into the sample input rail 51, the unqualified sample cups are screened by the guide door 53, and the qualified sample cups move in place under the transmission of the sample input rail 51; and the culture medium loading rotary table 10 rotates, the culture medium streaking rotary table 13 rotates anticlockwise, the culture medium boxes are manually/automatically and sequentially placed into the loading grooves one by one, and each loading groove has a plurality of culture medium boxes disposed in a stacking manner;
[0075] 2. the sample transfer device 2 grabs the sample cups to the position of the scanning device 4 from the sample input rail 51, the scanning device 4 carries out scanning on the codes on the sample cups, and if the codes are incorrect, the sample cups are grabbed onto the abnormal sample output rail 52 by the sample transfer device 2 and output by the abnormal sample output rail 52;
[0076] 3. the sample cups with the correct codes in the step 2 move to the position of the weight detection device 5 under the action of the sample transfer device 2, the weights of the sample cups are measured, if the weights are unqualified, the sample cups are grabbed onto the abnormal sample output rail 52 by the sample transfer device 2 and output by the abnormal sample output rail 52, and the sample cups with the qualified weights are transported to the filling location 6 by the sample transfer device 2;
[0077] 4. the sample cups located at the filling location 6 are filled with the sample treatment agent by the filling device 3;
[0078] 5. the sample cups obtained in the step 4 are fed into the shaking device 7, and the treatment agent and samples in the sample cups are shaken and uniformly mixed;
[0079] 6. the sample cups obtained in the step 5 are fed to the waiting locations 8;
[0080] 7. When it is detected that there are the sample cups at the waiting locations 8, the pushing device 11 pushes the culture medium box into the loading station, during pushing, the opening device 12 opens the culture medium box, and the culture medium streaking rotary table 13 rotates anticlockwise to take the culture medium box to the streaking station;
[0081] 8. after the inoculation needle is disinfected by the streaking assembly and is dipped into the sample in the sample cup, streaking is carried out on the culture medium box; and
[0082] 9. the streaked culture medium box rotates along with the culture medium streaking rotary table 13, is closed under the action of the culture medium storage box 48 and moves to the label printing station, and code marking is carried out on the culture medium box by the label printer 47; and the code-marked culture medium box is transferred into the culture medium storage box 48 by the boxing module 49.
[0083] In this embodiment, the sample transfer device 2, the first-region streaking module 28, the second-region streaking module 29 and the boxing module 49 are manipulators.
Embodiment 2
[0084] The structure principle of this embodiment is basically the same as that of Embodiment 1, and the differences lie in that in the streaking assembly, the first power unit 37 is a cylinder, and a piston rod of the cylinder is fixedly connected with the first sliding seat 36; the second power unit 40 is a cylinder, and a piston rod of the cylinder is fixedly connected with the first sliding seat 36; the third power unit is a cylinder, and a piston rod of the cylinder is fixedly connected with the third sliding seat 42.
Embodiment 3
[0085] The structure principle of this embodiment is basically the same as that of Embodiment 1, and the differences lie in that the workbench 1 is also provided with the sample cup opening and closing device, and the sample cup opening and closing device comprises the moving seat 54, the rotating body 55 vertically disposed in a penetrating manner in the moving seat 54, and the power assembly for driving the rotating body 55 to rotate around the central axis per se. The sample cup opening and closing device further comprises the following structure: a clamping jaw which is disposed at the bottom of the rotating body 55 and can implement opening and closing, the clamping jaw having a plurality of jaw portions which are circumferentially distributed and can be inserted into the corresponding grooves 94, and the number of the grooves 94 being a multiple of that of the jaw portions.
[0086] The specific embodiments described herein are merely used for illustrating the spirit of the present invention. Those skilled in the art of the present invention can make various modifications or supplementations to the described specific embodiments or adopt similar modes for replacement of the described specific embodiments, but cannot depart from the spirit of the present invention or go beyond the scope defined by the appended claims.