Magnetic resonance method and apparatus wherein signal contributions outside of the measurement region are reduced
09726743 · 2017-08-08
Assignee
Inventors
Cpc classification
G01R33/4836
PHYSICS
G01R33/561
PHYSICS
G01R33/5613
PHYSICS
International classification
G01V3/00
PHYSICS
G01R33/561
PHYSICS
Abstract
In magnetic resonance imaging using a measurement sequence of the “free precession of transverse magnetization in the steady state”-type i.e., an SSFP measurement sequence, during the SSFP measurement sequence, the implementation of a preparation sequence takes place to reduce a signal contribution of the transverse magnetization in an outer region surrounding a measurement region in the MR imaging. The implementation of the preparation sequence includes the radiation of a multidimensional, spatially selective RF pulse that acts in a spatially selective manner on the transverse magnetization in the outer region. Saturation of the transverse magnetization and/or dephasing of the transverse magnetization in the outer region can be achieved by the multidimensional, spatially selective RF pulse.
Claims
1. A method for acquiring magnetic resonance (MR) data from a subject, comprising: operating an MR data acquisition unit, with an examination subject situated therein, to implement a “free precession of transverse magnetization in the steady state”-type (SSFP) data acquisition sequence; in said SSFP data acquisition sequence, operating a radio-frequency (RF) radiator to radiate RF pulses that produce a transverse magnetization of nuclear spins in a measurement region of the examination subject and in an outer region of the examination subject that surrounds and adjoins said measurement region, said nuclear spins then emitting an MR signal; also in said SSFP data acquisition sequence, operating said MR data acquisition unit to execute a preparation sequence that reduces a signal contribution, to said MR signal, of nuclear spins having said transverse magnetization in said outer region, by radiating, via said RF radiator, a multidimensional, spatially selective RF pulse that by itself spatially selectively acts in at least two dimensions on said transverse magnetization of said nuclear spins in said outer region; and operating an RF detector of said MR data acquisition unit, in said SSFP data acquisition sequence, to detect said MR signals and to enter the detected MR signals into an electronic memory, organized as k-space, to produce an electronically accessible data file in said electronic memory.
2. A method as claimed in claim 1 comprising operating said MR data acquisition unit for saturate the transverse magnetization of said nuclear spins in said outer region by radiating said multidimensional, spatially selective RF pulse.
3. A method as claimed in claim 1 comprising operating said MR data acquisition unit to phase-incoherently excite said transverse magnetization of said nuclear spins in said outer region by radiating said multidimensional, spatially selective RF pulse.
4. A method as claimed in claim 1 comprising operating said MR data acquisition unit to dephase said transverse magnetization of said nuclear spins in said outer region by radiating said multidimensional, spatially selective RF pulse.
5. A method as claimed in claim 1 comprising operating said MR data acquisition unit to apply a gradient field, with a gradient system of said MR data acquisition unit, which dephases said transverse magnetization of said nuclear spins in said outer region.
6. A method as claimed in claim 1 comprising operating said MR data acquisition unit in said operation sequence to make said multidimensional, spatially selective RF pulse spatially selective by amplitude modulation of said multidimensional, spatially selective RF pulse by activating a spatially selective gradient field, during radiation of said multidimensional, spatially selective RF pulse, with a gradient system of said MR data acquisition unit.
7. A method as claimed in claim 1 wherein said RF radiator comprises a plurality of RF coils, and comprising operating said MR data acquisition unit to make said multidimensional, spatially selective RF pulse spatially selective by radiating chronologically overlapping RF energy from multiple RF coils, among said plurality of RF coils.
8. A method as claimed in claim 1, comprising: operating said MR data acquisition unit to radiate, at a beginning of said preparation sequence, an RF pulse that aligns said nuclear spins along a longitudinal direction of said MR data acquisition unit; and operate said MR data acquisition unit to radiate, at an end of said preparation sequence, a further RF pulse that aligns said transverse magnetization of said nuclear spins in a transverse plane that is orthogonal to said longitudinal direction.
9. A method as claimed in claim 8, comprising: operating said MR data acquisition unit, in said SSFP data acquisition sequence, to radiate excitation RF pulses that are alternating positive and negative a pulses; operating said MR data acquisition unit to radiate said RF pulse at said beginning of said preparation sequence as a positive α/2 pulse; and operating said MR data acquisition unit to radiate said RF pulse at said end of said preparation sequence as a positive α/2 pulse.
10. A method as claimed in claim 8, comprising: repeating radiation of said RF excitation pulses in said SSFP data acquisition sequence with a defined repetition time; operating said MR data acquisition unit to radiate said RF pulse at said beginning of said preparation sequence at a time interval, following a selected RF excitation pulse of said SSFP data acquisition sequence, that is half of said repetition time; and operating said MR data acquisition unit to radiate said RF pulse at said end of said preparation sequence at a time interval following a different selected RF excitation pulse of said SSFP data acquisition sequence, which is half of said repetition time.
11. A method as claimed in claim 1 comprising: operating said MR data acquisition unit, in said SSFP data acquisition sequence, to detect said MR signals from each of said measurement region and said outer region; operating said MR data acquisition unit in said preparation sequence to also detect MR signals from the transverse magnetization of said nuclear spins said outer region; in a processor, automatically calculating a signal contribution of said transverse magnetization of the nuclear spins in said outer region to said MR signals detected in said SSFP data acquisition unit sequence, based on said MR signals detected from said transverse magnetization of said nuclear spins in said outer region in said preparation sequence; and in said processor, correcting said MR signals detected in said SSFP data acquisition sequence by removal therefrom of the calculated signal contribution of the transverse magnetization of the nuclear spins in said outer region.
12. A method as claimed in claim 11 comprising operating said MR data acquisition unit to detect said MR signal from said transverse magnetization of said nuclear spins in said outer region in said preparation sequence, and calculating said signal contribution thereof, using an MR fingerprinting technique.
13. A method as claimed in claim 11, comprising: operating said MR data acquisition unit to execute said preparation sequence multiple times; operating said MR data acquisition unit, in successive repetitions of said preparation sequence, with at least one MR parameter of said MR data acquisition unit being different in the respective successive repetitions; and selecting said at least one MR parameter from the group consisting of a time between said successively repeated preparation sequences, a flip angle of said multidimensional, spatially selective RF pulse, an echo time for detection of said MR signal in the preparation sequence, phase coding produced by a gradient field activated by a gradient system of said MR data acquisition unit in said SSFP data acquisition sequence, a phase of said multidimensional, spatially selective RF pulse, an amplitude of said multidimensional, spatially selective RF pulse, a number of gradient fields applied by a gradient system of said MR data acquisition unit during said SSFP data acquisition sequence, and a type of spatially selective gradient fields applied by a gradient coil system of said MR data acquisition unit in said SSFP data acquisition sequence.
14. A method as claimed in claim 11, comprising: calculating said signal contribution of the transverse magnetization of nuclear spins in said outer region by comparing a time curve of said MR signals detected in said preparation sequence for said transverse magnetization of said nuclear spins in the outer region with pre-calculated model data.
15. A method as claimed in claim 1 comprising operating said MR data acquisition unit to radiate said multidimensional, spatially selective RF pulse in said preparation sequence with a pulse configuration that does not affect said transverse magnetization of nuclear spins in said measurement region.
16. An apparatus for acquiring magnetic resonance (MR) system, comprising: an MR data acquisition unit comprising a radio-frequency (RF) radiator, and an RF detector and an electronic memory; a control computer configured to operate the MR data acquisition unit, with an examination subject situated therein, to implement a “free precession of transverse magnetization in the steady state”-type (SSFP) data acquisition sequence; said control computer, in said SSFP data acquisition sequence, being configured to operate the RF radiator to radiate RF pulses that produce a transverse magnetization of nuclear spins in a measurement region of the examination subject and in an outer region of the examination subject that surrounds and adjoins said measurement region, said nuclear spins then emitting an MR signal; said control computer, also in said SSFP data acquisition sequence, being configured to operate said MR data acquisition unit to execute a preparation sequence that reduces a signal contribution, to said MR signal, of nuclear spins having said transverse magnetization in said outer region, by radiating, via said RF radiator, a multidimensional, spatially selective RF pulse that by itself spatially selectively acts in at least two dimensions on said transverse magnetization of said nuclear spins in said outer region; and said control computer being configured to operate the RF detector of said MR data acquisition unit, in said SSFP data acquisition sequence, to detect said MR signals and to enter the detected MR signals into the electronic memory, organized as k-space, to produce an electronically accessible data file in said electronic memory.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
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DESCRIPTION OF THE PREFERRED EMBODIMENTS
(11) In
(12) An RF coil arrangement 121 that can radiate an amplitude-modulated RF excitation pulse into the examined person 101 is provided for the excitation of the polarization of nuclear spins resulting in the basic magnetic field, namely the alignment of the magnetization in the longitudinal direction. A transverse magnetization of the nuclear spins can thereby be generated. To generate such RF excitation pulses, an RF transmission unit 131 is connected via an RF switch 130 with the RF coil arrangement 121. The RF transmission unit 131 can include an RF generator and an RF amplitude modulation unit. The RF excitation pulses can deflect the transverse magnetization slice-selectively in 1D or spatially selectively in 2d/3d out of the steady state.
(13) Furthermore, an RF reception unit 132 is coupled via the RF switch 130 with the RF coil arrangement 121. MR signals of the relaxing transverse magnetization can be acquired via the RF reception unit 132 as raw data, for example via inductive injection into the RF coil arrangement 121.
(14) In general, it is possible to use separate RF coil arrangements 121 for the radiation of the RF excitation pulses by means of the RF transmission unit 131 and for the acquisition of the raw data by means of the RF reception unit 132. For example, for the radiation of RF pulses and/or acquisition of raw data it can be possible to use an RF coil arrangement 121 which comprises an array of RF coils. For example, the RF coil arrangement 121 for the acquisition of the raw data can comprise 32 individual RF coils and be used in such a manner for parallel imaging (ppa imaging, partially parallel acquisition). Appropriate techniques are known to those skilled in the art, so additional details need not be explained herein.
(15) The MR system 100 furthermore has an operating unit 150 (console), for example, can include a monitor, a keyboard, a mouse, etc. User inputs can be detected and shown as an output to the user by means of the operating unit 150. For example, it can be possible for individual operating modes or operating parameters of the MR system to be set by the user and/or automatically and/or via remote control by means of the operating unit 150.
(16) Furthermore, the MR system 100 has a computer 160. For example, the computer 160 can be configured to generate an MR image from the raw data acquired by means of the RF reception unit. For this purpose, for example, techniques for post-processing apparatus imaging can be applied and/or corresponding Fourier transformations can be applied between the positional frequency space in which the raw data exist and the positional space in which the MR image is obtained. For example, the computer 160 can furthermore control the implementation of an MR measurement sequence. For this, the units 131, 132, 140 can be controlled and RF pulses can be radiated such that gradient fields are applied and MR signals are acquired.
(17) By means of the MR measurement sequence MR imaging for a measurement region 400, which includes an inside of the examined person 101, can be implemented. As is clear from
(18) The measurement region 400 can be selectively imaged as an ROI with a relatively short measurement duration. In particular, in an application such as cardiac imaging it can be worthwhile to achieve such a reduced measurement duration in order to reduce movement artifacts via suitable techniques.
(19) Although the individual units of the MR system 100 that are discussed in the preceding are depicted separately in
(20) An SSFP measurement sequence 300 is shown in
(21) The RF pulses 201 of the SSFP measurement sequence 300 can be conventional RF pulses to excite the transverse magnetization. In particular, the RF pulses 201 can only have a 1D spatial selectiveness with regard to a slice selection direction (which can typically be oriented parallel to the longitudinal direction of the tube 111 of the MR system 100). For example, this can occur by the application of a slice-selection gradient field by means of the gradient unit 140. In such a case, the RF pulses 201 can in particular have no spatial selectiveness orthogonal to the slice selection direction, such that transverse magnetization is excited both within the measurement region 400 and within the outer region 401. The signal contribution of the transverse magnetization in the outer region can arise in the MR imaging.
(22) A corresponding SSFP measurement sequence 300 is shown in
(23) The preparation sequence 310 enables a signal contribution of the transverse magnetization in the outer region 401 to be reduced in the MR imaging. Details of the preparation sequence 310 are explained in the following.
(24) As can be seen from
(25) For example, it is possible that the RF pulses 202-1, 202-2 are conventional RF pulses which only have a 1D spatial selectiveness, for example. In other words, this means that the RF pulses 202-1, 202-2 in the transverse plane act in the same manner on the transverse magnetization in the measurement region 400 and the outer region 401.
(26) Furthermore, from
(27) With a chronological sequence of RF pulses 201, 202-1, 202-2 as discussed above with regard to
(28) Although the duration of the preparation sequence 310 can be limited to define values, it cannot be bounded. Nevertheless, it can be desirable to minimize a complete duration required for implementation of the preparation sequence 310 or, respectively, to temporally limit it to a few milliseconds. Otherwise, the steady state can be disrupted and/or the measurement duration can be increased. In the following, techniques are explained which enable the fast implementation of the preparation sequence 310 using multidimensional, spatially selective RF pulses to reduce the signal contribution of the transverse magnetization in the outer region 401 to the MR imaging.
(29) The preparation sequence 310 is shown in greater detail in
(30) Such multidimensional, spatially selective RF pulses 200 are depicted with regard to
(31) For example, in
(32) In general, it is not necessary that the parameters of the multidimensional, spatially selective RF pulse are selected such that a phase-coherent excitation of the transverse magnetization is achieved. In other words: it can be unnecessary that the transverse magnetization excited via the multidimensional, spatially selective RF pulse 200 has a well-defined phase position. This can in particular be the case when the multidimensional, spatially selective RF pulse 200 is used for a saturation by complete deflection of the longitudinal magnetization in the outer region 401 out of the steady state.
(33) With regard to
(34) A flowchart of a method according to the invention for MR imaging by means of an SSFP measurement sequence 300 is shown in
(35) In Step S3 a check is made as to whether a criterion for implementation of the preparation sequence 310 is satisfied. In other words: in Step S3 a check is made as to whether the implementation of the preparation sequence 310 is necessary and/or possible at a defined point in time during the SSFP measurement sequence 300. For example, it can be possible that the preparation sequence 310 is implemented repeatedly with a defined repetition rate and/or a defined minimum time interval. For example, the repetition rate of the preparation sequence 310 is dependent on a relaxation time of the transverse magnetization, in particular in an outer region 401. Moreover, the insertion of the preparation sequence 310 into the SSFP measurement sequence 300 can occur such that a defined time interval 231 is maintained between the RF pulses 201 of the SSFP measurement sequence 300 and the RF pulses 202-1, 202-2 to store the transverse magnetization within the scope of the preparation sequence 310. This criterion can also be checked within the scope of Step S3.
(36) If it is established in Step S3 that the criterion or criteria for the implementation of the preparation sequence 310 is/are not satisfied, in Step S5 a check is made as to whether the SSFP measurement sequence has already ended, i.e. whether all MR signals or, respectively, raw data for the MR imaging have already been acquired within the scope of the SSFP measurement sequence at 100. If this is not the case, Step S3 is implemented again, or the SSFP measurement sequence is continued. However, if the SSFP measurement sequence has ended, the method ends in Step S6.
(37) If it is established in Step S3 that the criterion for implementation of the preparation sequence 310 has been satisfied, the preparation sequence 310 is implemented in Step S4 to reduce the signal contribution of the magnetization in the outer region 401. The implementation of the preparation sequence 310 in Step S4 includes the radiation of a multidimensional, spatially selective RF pulse 200 which acts in a spatially selective manner on the transverse magnetization in the outer region 401. In the following, Step S4 is explained in detail with regard to
(38) Referring first to
(39) The radiation of a multidimensional, spatially selective RF pulse 200 subsequently takes place in Step T2 to saturate and/or dephase the transverse magnetization in the outer region 401.
(40) The application of a gradient field 225 to further dephase the transverse magnetization in the outer region 401 optionally takes place in Step T3.
(41) The radiation of an additional RF pulse 202-2 to reestablish the transverse magnetization via alignment of said transverse magnetization in a transverse plane orthogonal to the longitudinal direction takes place in Step T4, at the end of the preparation sequence 310. In other words: in Step T4, the transverse magnetization previously stored in Step T1 is reestablished. The implementation of the SSFP measurement sequence 300 can then be continued.
(42) An additional preparation sequence 310 is illustrated in
(43) The radiation of a multidimensional, spatially selective RF pulse 200 to generate transverse magnetization in the outer region 401 takes place in Step U2. In contrast to Step T2, as discussed in the preceding with reference to
(44) It can therefore be possible to acquire an MR signal of the transverse magnetization in the outer region in Step U3. Based on the MR signal acquired in Step aU3, a signal contribution of the transverse magnetization in the outer region on the MR signals acquired with the SSFP measurement sequence can be calculated and the MR signals can be corrected accordingly. The signal contribution of the transverse magnetization in the outer region to the MR imaging can thereby be suppressed or, respectively, reduced.
(45) It is possible that Steps U3 and U4 are implemented by means of the MR fingerprinting technique. For example, for this multiple preparation sequences 310 can be inserted into the SSFP measurement sequence 300. Different MR parameters can be varied between the repeated executions of the preparation sequence 310. The obtained MR signals can be compared with pre-calculated model data, and the signal contribution of the transverse magnetization in the outer region to the MR imaging can be calculated in such a manner.
(46) Appropriate MR fingerprinting techniques are known to those skilled in the art, such that additional details need not be explained herein.
(47) Although modifications and changes may be suggested by those skilled in the art, it is the intention of the inventor to embody within the patent warranted hereon all changes and modifications as reasonably and properly come within the scope of his contribution to the art.