ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL PROPERTIES

Abstract

The present invention relates to novel active compound combinations comprising at least one compound of group (I) (I-1) or (I-2) and at least one further active fungicidal compound, which combinations are highly suitable for controlling animal and microbial pests such as unwanted insects.

##STR00001##

Claims

1: An active compound combination, comprising a synergistically effective combination of at least one compound of group (I), wherein the compound of group (I) is ##STR00003## and at least one fungicide of group (II), wherein the fungicide of group (II) is carbendazim, fluxapyroxad, penthiopyrad, picoxystrobin, pyraclostrobin, thiram, isoflucypram, fluoxapiproline, pydiflumetofen, thiabendazole, thiophanate-methyl or oxathiapiproline.

2: The active compound combination according to claim 1, wherein the fungicide of group (II) is isoflucypram, fluoxapiproline or pydiflumetofen.

3: The active compound combination according to claim 1, wherein the fungicide of group (II) is fluoxapiproline or pydiflumetofen.

4: The active compound combination according to claim 1, comprising a mixture of the compounds of the formula (I-1) and (I-2).

5: The active compound combination according to claim 4, where the compound of the formula (I-1) to the compound of the formula (I-2) is present in a mixing ratio from 80:20 to 99:1.

6: The active compound combination according to claim 1, wherein the ratio of the compound of group (I) to the compound of group (II) is from 500:1 to 1:50.

7: The active compound combination according to claim 1, wherein the ratio of the compound of group (I) to the compound of group (II) is from 300:1 to 1:30.

8: An agrochemical composition, comprising an active compound combination according to claim 1, with one or more extenders and/or one or more surfactants.

9: A method for controlling animal pests in a plant, comprising applying an active compound combination according to claim 1 to the plant or any plant part thereof.

10: A method, comprising applying an active compound combination according to claim 1 to a plant or any plant part thereof as a plant-strengthening agent.

11: The method of claim 9, wherein the plant part is a seed.

12: The method of claim 9, wherein the plant is a transgenic plant.

13: A method for controlling animal pests in the domestic sector, in the hygiene sector and in the protection of stored products, comprising applying an active compound combination according to claim 1.

14: A method for controlling animal or microbial pests, comprising applying an active compound combination according to claim 1 to animal or microbial pests and/or their habitat.

15: A process for preparing a crop protection agent, comprising mixing an active compound combination according to claim 1, with one or more extenders and/or one or more surfactants.

16: The active compound combination according to claim 4, wherein the ratio of the mixture of compounds of the formula (I-1) and (I-2) to the compound of group (II) is from 500:1 to 1:50.

17: The active compound combination according to claim 4, wherein the ratio of the mixture of compounds of the formula (I-1) and (I-2) to the compound of group (II) is from 300:1 to 1:30.

Description

EXAMPLES

Formula for the Efficacy of the Combination of Two Compounds

[0158] The expected efficacy of a given combination of two compounds is calculated as follows (see Colby, S. R., “Calculating Synergistic and antagonistic Responses of Herbicide Combinations”, Weeds 15, pp. 20-22, 1967):

If

[0159] X is the efficacy expressed in % mortality of the untreated control for test compound A at a concentration of m ppm respectively m g/ha,
Y is the efficacy expressed in % mortality of the untreated control for test compound B at a concentration of n ppm respectively n g/ha,
E is the efficacy expressed in % mortality of the untreated control using the mixture of A and B at m and n ppm respectively m and n g/ha,
then is

[00001]$E=X+Y-\frac{X\times Y}{100}$

[0160] If the observed insecticidal efficacy of the combination is higher than the one calculated as “E”, then the combination of the two compounds is more than additive, i.e. there is a synergistic effect.

Example A

[0161] Spodoptera frugiperda—Spray Test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: alkylaryl polyglycol ether

[0162] To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amount of solvent and is diluted with water, containing an emulsifier concentration of 1000 ppm, to the desired concentration. Further test concentrations are prepared by dilution with emulsifier containing water.

[0163] Cotton leaves (Gossypium hirsutum) are treated by being sprayed with the preparation of the active compound of the desired concentration and are infested with caterpillars of the fall army worm (Spodoptera frugiperda).

[0164] After the specified period of time mortality in % is determined. 100% means all the caterpillars have been killed and 0% means none of the caterpillars have been killed. The mortality values determined thus are recalculated using the Colby-formula (see above).

[0165] According to the present application in this test e.g. the following combinations show a synergistic effect in comparison to the single compounds:

TABLE-US-00003 TABLE 1.1 Spodoptera frugiperda- test Concentration Mortality Avtive ingredient in ppm in % after 2 days Tetraniliprole 0.06 20 Pydiflumetofen 1.5 0 Tetraniliprole + Pydiflumetofen obs.* calc.** (1:25) 0.06 + 1.5 70 20 According to the invention

TABLE-US-00004 TABLE 1.2 Spodoptera frugiperda- test Concentration Mortality Avtive ingredient in ppm in % after 3 days Tetraniliprole 0.12 80 0.06 30 Pydiflumetofen 3 0 1.5 0 Tetraniliprole + Pydiflumetofen obs.* calc.** (1:25) 0.12 + 3   100 80 (1:25) 0.06 + 1.5 100 30 According to the invention

TABLE-US-00005 TABLE 1.3 Spodoptera frugiperda- test Concentration Mortality Avtive ingredient in ppm in % after 6 days Tetraniliprole 0.06 60 Fluoxapiprolin 1.5 0 Tetraniliprole + Fluoxapiprolin obs.* calc.** (1:25) 0.06 + 1.5 100 60 According to the invention Pydiflumetofen 1.5 0 Tetraniliprole + Pydiflumetofen obs.* calc.** (1:25) 0.06 + 1.5 100 60 According to the invention *obs. = observed insecticidal efficacy, **cal. = efficacy calculated with Colby-formula

Example B

[0166] Phaedon cochleariae—Spray Test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: alkylaryl polyglycol ether

[0167] To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amount of solvent and is diluted with water, containing an emulsifier concentration of 1000 ppm, to the desired concentration. Further test concentrations are prepared by dilution with emulsifier containing water.

[0168] Cabbage leaves (Brassica oleracea) are treated by being sprayed with the preparation of the active compound of the desired concentration and are infested with mustard beetle larvae (Phaedon cochleariae).

[0169] After the specified period of time mortality in % is determined. 100% means all the beetle larvae have been killed and 0% means none of the beetle larvae have been killed. The mortality values determined thus are recalculated using the Colby-formula (see sheet 1).

[0170] According to the present application in this test e.g. the following combinations show a synergistic effect in comparison to the single compounds:

TABLE-US-00006 TABLE 2.1 Phaedon cochleariae- test Concentration Mortality Avtive ingredient in ppm in % after 1 day Tetraniliprole 0.24 30 0.12 10 Fluoxapiprolin 6 0 3 0 Tetraniliprole + Fluoxapiprolin obs.* calc.** (1:25) 0.24 + 6 60 30 (1:25) 0.12 + 3 40 10 According to the invention

TABLE-US-00007 TABLE 2.2 Phaedon cochleariae- test Concentration Mortality Avtive ingredient in ppm in % after 2 days Tetraniliprole 0.12 40 Fluoxapiprolin 3 0 Tetraniliprole + Fluoxapiprolin obs.* calc.** (1:25) 0.12 + 3 70 40 According to the invention *obs. = observed insecticidal efficacy, **cal. = efficacy calculated with Colby-formula