FOAMABLE DENTAL CARE COMPOSITION, SYSTEM CONSISTING OF THE DENTAL CARE COMPOSITION AND A DISPENSER, AND USE OF THE DENTAL CARE COMPOSITION IN A METHOD FOR SIMULTANEOUSLY CLEANING SEVERAL, PREFERABLY ALL, TEETH

Abstract

The present disclosure relates to foamable dental care compositions and their use thereof for cleaning and caring of the teeth and mouth. With the preparation in foam or aerosol form, the composition can be applied evenly, quickly and efficiently on mouth inserts, cleaning prostheses and other devices used for the simultaneous cleaning of several or all teeth at the same time. The handling is considerably simplified.

Claims

1. A dental care and dental cleaning composition for use in a method of simultaneously cleaning a plurality of teeth of a upper and/or lower jaw by means of a dental brushing device suitable therefor, wherein the dental care and dental cleaning composition is presented in foamed form on at least one mouth insert of the dental brushing device, and wherein the dental care and teeth cleaning composition comprising: 10 to 40 wt % glycerol, 10 to 23.5 wt % of at least one precipitated silicate, 0.05 to 0.5 wt %, of at least one viscosity amplifier, at least one surfactant in a proportion of 0.2 to 4.0 wt %, and at least 10 wt % of water.

2. The dental care and dental cleaning composition for use according to claim 1 in a method for prevention and/or treatment of dental and gum diseases, in particular caries, periodontitis and/or plaque.

3. A dental care and dental cleaning composition comprising: 15 to 30 wt %, of glycerol, at least one further humectant, besides glycerol, wherein the at least one further humectant is comprised sorbitol or hydrogenated starch hydrolysate having a sorbitol proportion in the range of 65 to 75 wt %, 10 to 23.5 wt % of a mixture of two or more precipitated silicates, 0.2 to 4.0 wt %, of at least one surfactant, 0.05 to 0.5 wt %, of at least one viscosity amplifier, at least one active substance and/or at least one suitable excipient or additive, and at least 10 wt % of water, wherein the mixture of two or more precipitated silicates comprises first precipitated silicate with an average particle size in a of 7 to 8.5 μm and an Einlehner abrasion in the range of more than 5.0 to 25 mg loss/100 000 revolutions, second precipitated silicate with an average particle size in the range of more than 8.5 to 10 μm and an Einlehner abrasion in the range of more than 2.5 to 5.0 mg loss/100 000 revolutions, and third precipitated silicate with an average particle size in the range of more than to 14 μm and an Einlehner abrasion in the range of less than 2.5 loss/100 000 revolutions, the composition does not include polyethyleneglycol or the proportion of polyethyleneglycol in the composition is at most 0.8 wt. %, and the at least one viscosity amplifier is Xanthan Gum, and the proportion of cellulose or cellulose-derivates and/or algal polysaccharides, in particular Carragenaan, in the composition is at most 0 to 0.1 wt. %.

4. The dental care and dental cleaning composition according to claim 3, wherein the composition comprises as further humectant hydrogenated starch hydrolysate having a sorbitol proportion in the range of 65 to 75 wt %, or sorbitol, or the further humectant is hydrogenated starch hydrolysate having a sorbitol proportion in the range of 65 to 75 wt %, or sorbitol.

5. The dental care and dental cleaning composition according to claim 4, wherein the composition comprises 16.25% to 30 wt % of sorbitol.

6. The dental care and dental cleaning composition according to claim 3, wherein the composition comprises a viscosity in the range of 200 to 30,000 mPa s measured with a Brookfield DV2T rotational viscometer with Heliopath T spindles of spindle type C, at a rotational speed of 10 rpm, 20° C. and 1013.25 mbar.

7. (canceled)

8. (canceled)

9. The dental care and dental cleaning composition according to claim 3, wherein the composition does not include polyethylene glycol or the proportion of polyethylene glycol in the composition is at most 0.4 wt %.

10. The dental care and dental cleaning composition according to claim 3, wherein the proportion of cellulose or cellulose derivatives and/or algal polysaccharides, in particular Carragenaan, in the composition is in the range of 0 to 0.05 wt %.

11. The dental care and dental cleaning composition according to claim 3, wherein the composition further comprises at least one active substance selected from the group consisting of one or more compounds for remineralisation or ceramization such as hydroxyapatite, one or more fluoride active substances, a gum care agent, a disinfectant component and any mixture thereof, wherein the proportion of the one or more active substances in the composition is preferably 0.5 to 8 wt %.

12. The dental care and dental cleaning composition according to claim 3, wherein the composition further comprises: 16.25 to 30 wt % sorbitol, 15 to 30 wt %, glycerol, 1 to 2 wt % of amine fluoride-containing raw material with 20-50% active substance proportion, 6 to 13 wt. % precipitated silicate of category 1, 3 to 7 wt. % precipitated silicate of category 2, 1 to 3.5 wt. % precipitated silicate of category 3, 0.1-2 wt. % sodium lauryl sulphate, 0.1-2 wt. % cocamidopropyl betaine, 0.05-0.2 wt. % xanthan gum, and at least 10 wt % of water.

13. The dental care and dental cleaning composition according to claim 3, wherein the composition comprises usual excipients and additives selected from the group consisting of flavourings, sweeteners, conserving agents, pigments, colourants, buffer substances and any mixture thereof, wherein the proportion of the one or more excipients and additives in the composition is preferably 0.1-5 wt %.

14. The dental care and dental cleaning composition according to claim 3, wherein the composition is in the form of a foam or an aerosol.

15. A system comprising a dental care and dental cleaning composition according to claim 3 and a dispenser having means for storing, conveying and dispensing the dental care and dental cleaning composition, wherein the means for dispensing the composition comprises an outlet valve having an outlet opening, and wherein the composition and the means for dispensing cooperate such that upon actuation of the outlet valve the dental cleaning composition exits the outlet opening in a stranded form.

16. The system of claim 15, wherein the means for conveying conveys the composition by means of a propellant gas or propellant gas mixture, and the means for dispensing is formed to be sufficiently pressure stable with respect to an expansion pressure of the propellant gas or propellant gas mixture.

17. The system according to claim 15, wherein the means for storing and dispensing the composition is an aerosol can or a bag-on-valve can.

18. The system according to claim 15, wherein the dental care and dental cleaning composition is provided in combination with a propellant gas or propellant gas mixture, in particular wherein the dental care and dental cleaning composition comprises a propellant gas or propellant gas mixture which is a compressible liquid having a boiling point of −10° C. or higher at normal pressure, or wherein the propellant gas or propellant gas mixture is not a compressible liquid, preferably dinitrogen oxide.

19. The system according to claim 18, wherein the propellant gas proportion of the composition is 0 to 15 wt %, or in the case of a non-compressible liquid, preferably dinitrogen oxide, the resulting pressure is in the range of 6 to 10 bar.

20. A method for simultaneously cleaning a plurality of teeth of a subject, wherein the tooth cleaning method comprising the following steps of: providing a dental care and dental cleaning composition comprising 10 to 40 wt % glycerol, 10 to 23.5 wt % of a mixture of two or more precipitated silicates, 0.05 to 0.5 wt % of at least one viscosity amplifier, at least one surfactant having a proportion of 0.2 to 4.0 wt %, and at least 10 wt % water, coating/applying the composition to at least one mouth insert of a vibratory tooth brushing device for the simultaneously cleaning of a plurality teeth of a user, inserting the at least one mouth insert with the composition into a mouth of the user, and cleaning the plurality of the user's teeth with the at least one mouth insert and the composition by activating the vibratory tooth brushing device.

21. The method according to claim 20, wherein the provided dental care and dental cleaning composition is a composition according to claim 3.

22. (canceled)

23. The dental care and dental cleaning composition according to claim 3 for use in a method of preventing and/or treating dental and gum diseases, in particular caries, periodontitis and plaque.

Description

SHORT DESCRIPTION OF THE FIGURES

[0232] FIG. 1 shows an embodiment of a mouth insert of a tooth brushing device, which is suitable for the simultaneous cleaning of all teeth of a user and for the application of the composition according to the invention. The mouth insert comprises a coupling section for connecting the mouth insert with a drive device of the tooth brushing device (not shown).

[0233] FIG. 2 shows a supervision on a part of a mouth insert with cleaning structures contained therein.

[0234] FIG. 3 is a vertical longitudinal cross-sectional view of a tooth brushing device for the simultaneous cleaning of all teeth of a user within the meaning of the present invention.

[0235] FIG. 4A to 4D are each vertical longitudinal cross-sectional views of coupling-portions of different embodiments for a mouth insert of a tooth brushing device, which is suitable for simultaneous cleaning of all teeth of a user.

[0236] FIG. 5 is a perspective view of a support structure for another embodiment of a mouth insert of a tooth brushing device, which is suitable for simultaneous cleaning of all teeth of a user.

[0237] FIG. 6 is a flowchart of a method for the simultaneous cleaning of several, preferably all teeth of a user.

[0238] FIG. 7A to 7F show photographic images, in negative representation, for the foam stability of a composition according to the invention (each left) compared to a composition with low glycerin and water content (each right) over time. FIG. 7A shows the foams at time point 0 seconds, FIG. 7B shows the foams at the time point 30 seconds, FIG. 7C shows the foams at the time point 1 minute, FIG. 7D shows the foams at the time point 2 minutes, FIG. 7E shows the foams at the time point 3.5 minutes and FIG. 7F shows the foams at the time point 5 minutes.

[0239] FIG. 8 represents the decrease in the foam volume depending on the time. Comparing a composition according to the invention (marked as “invention”) and a composition with low glycerin and water content (marked as “reference”).

MEASUREMENT METHODS

[0240] In the present invention, the determination of the viscosity is carried out with a Brookfield viscosimeter, preferably a rotary viscosimeter DV2T of the company Brookfield with heliopath T-spindles of spindle type C. The measurement is carried out at a speed of 10 rpm (revolutions per minute), 20° C. and normal pressure of 0.1 MPa (1013.25 mbar).

[0241] By measuring the torque required for the rotation of the spindle via the deflection of a spring, the viscosity of the composition according to the invention is determined.

[0242] The viscosity of the liquid composition is determined without propellant gas, i.e. at a time point before the composition according to a preferred embodiment is converted into a foam or an aerosol.

[0243] The viscosities or viscosity areas indicated above are therefore referred to in each case with a Brookfield viscometer, preferably a rotary viscosimeter DV2T of the company Brookfield, with heliopath T spindles of spindle type C at a speed of 10 rpm (revolutions per minute), 20° C. and normal pressure of 0.1 MPa (1013,25 mbar) measured dynamic viscosities in the composition without propellant gas.

[0244] The determination of the specific surface in (m.sup.2/g) according to the BET-method by the adsorption of gases, for example of nitrogen N.sub.2, is carried out according to Brunauer, Emmett and Teller according to DIN 66131.

[0245] The average particle size of the silicates is determined using a Leeds and Northrup Microtrac II. A laser beam is projected through a transparent cell containing a stream of moving particles suspended in a liquid. Light rays that hit the particles are scattered around angles that are inversely proportional to their size. The photodetector arrangement measures the amount of light at several predetermined angles. Electrical signals, which are proportional to the measured luminous flux values, are then processed by a microcomputer system to form a multi-channel histogram of particle size distribution.

[0246] The RDA value is determined according to the method described in the article “A Laboratory Method for Assessment of Dentifrice Abrasivity”, John J. Hefferren, in the Journal of Dental Research, Vol. 55, No. 4 (1976), pages 563-573.

[0247] The brass Einlehner (BE) abrasion value or the Einlehner abrasion was measured by the use of a Einlehner AT-1000 abrasion tester. In this test, a Fourdrinier brass wire sieve is weighed and exposed to the effect of a 10%/aqueous silicate suspension for a certain number of revolutions and the abrasion quantity is then determined as a milligram material loss from the Fourdrinier wire sieve per 100,000 revolutions. The result is the 10% brass Einlehner-(BE) abrasion value.

[0248] The rotary body of the abrasion tester runs uniformly at 1800 rpm regardless of the power frequency (50/60 Hz). The silicate suspension is produced by mixing the silicate to be tested with deionized Wasser. For the preparation-a 10% suspension, for example, 100 g silicate are mixed with 900 g of water.

EXAMPLES

Example 1: Dental Care Composition

[0249] In a vacuum homogenizer, the following steps are performed at 6000 revolutions per minute to produce a basic dental care formulation: [0250] 1. Presentation of 1500 g hydrogenated starch hydrolysate with a sorbitol content of 70% [0251] 2. Addition of 100 g of olaflur (aminfluoride-containing raw material with an active substance content of 35%) [0252] 3. Addition of 2000 g or 1700 g glycerin [0253] 4. Homogenizing the mixture obtained in this way for 10 min [0254] 5. Addition of 500 g Zeodent 115 [0255] 6. Addition of 300 g Zeodent 167 [0256] 7. Addition of 500 g Zeodent 103 [0257] 8. Homogenizing the mixture obtained in this way for 10 min [0258] 9. Addition of 6 g Xanthan Gum [0259] 10. Addition of 4 g acrylate cross polymer C10-C30 [0260] 11. Homogenizing the mixture obtained in this way for 10 min [0261] 12. Addition of 50 g sodium lauryl sulfate [0262] 13. Addition of 10 g of cocamidopropyl betaine [0263] 14. Homogenizing the mixture obtained in this way for 10 min [0264] 15. Adding water ad 6000 g [0265] 16. Setting pH=7.0 with sodium hydroxide

[0266] During the filling process of the resulting composition in a bag of a bag-on-valve can, the composition is added 4.9 wt.-% cosmetic foaming machine (propellant gas), based on the propellant gas-containing composition.

[0267] The above-mentioned exemplary composition can be manually distributed in the mouthpieces by spraying as foam or aerosol therein. It has been shown that the composition is distributed very evenly in the recesses of the mouthpiece.

[0268] It has also been shown that in particular the cleaning substance, but also the other active substances are evenly distributed in the foam or aerosol. This ensures that local overdoses or underdosage are avoided. Thus, with the composition of the invention, very good cleaning results could be achieved.

[0269] The exemplary composition has also been advantageous in that it—and the foam formed from it adheres well and sufficiently long to the mouth piece to allow an insertion of the mouthpieces into the oral cavity, without it—or the foam running out of the mouth and back. This was particularly true for the composition or foam of the recess opened downwards for the absorption of the teeth of the lower jawline, in upside down position.

[0270] In the mouth, however, the foam disintegrates again.

[0271] The adhesion is measurable with a tensiometer.

Example 2: Dental Care Composition

[0272] In a vacuum homogenizer, the following steps are performed at 6000 revolutions per minute to produce a basic dental care formulation: [0273] 1. Presentation of 1500 g sorbitol [0274] 2. Addition of 100 g of olaflur (aminfluoride-containing raw material with an active substance content of 35%) [0275] 3. Addition of 1700 g glycerin [0276] 4. Homogenizing the mixture obtained in this way for 10 min [0277] 5. Addition of 500 g Zeodent 115 [0278] 6. Addition of 300 g Zeodent 167 [0279] 7. Addition of 500 gZeodent 103 [0280] 8. Homogenizing the mixture obtained in this way for 10 min [0281] 9. Addition of 6 g Xanthan Gum [0282] 10. Addition of 4 g acrylate cross polymer C10-C30 [0283] 11. Homogenizing the mixture obtained in this way for 10 min [0284] 12. Addition of 50 g sodium lauryl sulfate [0285] 13. Addition of 10 g of cocamidopropyl betaine [0286] 14. Homogenizing the mixture obtained in this way for 10 min [0287] 15. Adding water ad 6000 g [0288] 16. Setting pH=7.0 with sodium hydroxide

[0289] During the filling process of the resulting composition in a bag of a bag-on-valve can, the composition is added 4.9 wt. % cosmetic foaming machine (propellant gas), based on the propellant gas-containing composition.

[0290] The above-mentioned exemplary composition can be manually distributed in the mouthpieces by spraying as foam or aerosol into the mouthpieces. It has been shown that the composition is distributed very evenly in the recesses of the mouthpiece.

[0291] It has also been shown that in particular the cleaning substance, but also the other active substances are evenly distributed in the foam or aerosol. This ensures that local overdoses or underdosage are avoided. Thus, with the composition of the invention, very good cleaning results could be achieved.

[0292] The exemplary composition has also been advantageous in that it- and the foam formed from it adheres well and sufficiently long to the mouth piece to allow an insertion of the mouthpieces into the oral cavity, without it- or the foam running out of the mouth and back. This was particularly true for the composition or foam of the recess opened downwards for the absorption of the teeth of the lower jawline, in upside down position. In the mouth, however, the foam disintegrates again.

[0293] The adhesion is measurable with a tensiometer.

Example 3: Performance Test of Dental Care Composition

[0294] In order to check whether the compositions of the invention are suitable for application in a mouthpiece for simultaneous cleaning of all teeth of a user, an exemplary composition with a glycerin content of 25 wt.-% and a water content of 18 wt.-% was compared with a non-inventive composition containing 8 wt.-% glycerin and 9 wt.-% water.

[0295] Both compositions were applied from the bag-on-valve can in strand form to a glass plate and the foam adhesion and the decay of the foams were examined over time (0 seconds to 5 minutes).

[0296] The results are shown in FIG. 7 A-F. The foam according to the invention (left) is characterized by a sufficiently long foam stability for applying the composition to a mouthpiece. However, the foam then disintegrates again as desired. In comparison, the non-inventive composition (right) foams very strongly and the foam does not collapse even after a long time.

Example 4: Quantification of Foam Volume

[0297] The compositions according to Example 3 were filled into commercially available plastic measuring cylinders and the percentage decrease of the menisci (due to the foam decay) was determined depending on the time.

[0298] The results are shown in FIG. 8. It is confirmed that the composition according to the invention shows the desired short-term foam stability, but the foam then, as desired, disintegrates again.