DISINFECTING COMPOSITION FOR TOPICAL USE

Abstract

Disclosed is a disinfecting composition for topical use, including a surfactant mixture based on cocoyl glutamate and alkyl polyglycosides, at least one thickening and/or gelling agent, and at least one disinfectant.

Claims

1. A disinfecting composition (C.sub.D) suitable for topical use comprising, per 100% of mass a)—from 35% to 99.3% by mass of water; b)—from 0.5% to 40% by mass of at least one disinfectant; c)—from 0.1% to 10% by mass of at least one gelling agent and/or thickener (AG); d)—from 0.1% to 15% by mass of a mixture (M.sub.1) comprising, per 100% of the mixture's own mass: (i)—from 50% to 99% by mass of a composition (C.sub.1) comprising, per 100% of mass of the composition (C.sub.1): (α)—from 65% to 90% by mass of at least one compound of formula (I):
R.sub.1—C(═O)—NH—CH(COOH)—(CH.sub.2).sub.2—COOH  (I) in acid, partially salified or totally salified form, wherein the group R.sub.1—C(═O)— represents a linear or branched, saturated or unsaturated acyl radical including from 8 to 18 carbon atoms, and (β)—from 10% to 35% by mass of at least one compound of formula (II):
R.sub.1—C(═O)—OH  (II) in acid, partially salified or totally salified form, wherein the group R.sub.1 is as defined for formula (I), (ii)—from 1% to 50% by mass of a composition (C.sub.2) comprising, per 100% of its mass: (γ)—from 14% to 80% by mass of a composition (C.sub.3) or of a mixture of compositions (C.sub.3), said composition (C.sub.3) being represented by formula (III):
R.sub.3—O-(G.sub.3).sub.p-H  (III) wherein R.sub.3 represents a linear or branched, saturated or unsaturated aliphatic radical including from 12 to 16 carbon atoms, G.sub.3 represents the residue of a reducing sugar and p represents a decimal number greater than or equal to 1.05 and less than or equal to 5; (δ)—from 20% to 80% of a composition (C.sub.4) or of a mixture of compositions (C.sub.4), said composition (C.sub.4) being represented by formula (V):
R.sub.4—O-(G.sub.4).sub.q-H  (V) wherein R.sub.4 represents a linear aliphatic radical, chosen from n-butyl (n-C.sub.4H.sub.9—), n-pentyl (n-C.sub.5H.sub.11—), n-hexyl (n-C.sub.6H.sub.13—) and n-heptyl (n-C.sub.7H.sub.15—) radicals, G.sub.4 represents a reducing sugar residue and q represents a decimal number greater than or equal to 1.05 and less than or equal to 5.

2. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the gelling agent and/or thickener (AG) is chosen from polysaccharides consisting of monosaccharide derivatives, polysaccharides consisting solely of monosaccharides, cellulose and cellulose derivatives, starches and linear or branched or crosslinked polyelectrolytes.

3. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the composition (C.sub.3) consists of a mixture of compounds represented by formulae (III.sub.1), (III.sub.2), (III.sub.3), (III.sub.4) and (III.sub.5):
R.sub.3—O-(G.sub.3).sub.1-H  (III.sub.1),
R.sub.3—O-(G.sub.3).sub.2-H  (III.sub.2),
R.sub.3—O-(G.sub.3).sub.3-H  (III.sub.3),
R.sub.3—O-(G.sub.3).sub.4-H  (III.sub.4),
R.sub.3—O-(G.sub.3).sub.5-H  (III.sub.5), in the respective molar proportions a.sub.1, a.sub.2, a.sub.3, a.sub.4 and a.sub.5 such that: the sum a.sub.1+a.sub.2+a.sub.3+a.sub.4+a.sub.5 is equal to 1, and the sum a.sub.1+2a.sub.2+3a.sub.3+4a.sub.4+5a.sub.5 is equal to p.

4. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the composition (C.sub.4) consists of a mixture of compounds represented by formulae (V.sub.1), (V.sub.2), (V.sub.3), (V.sub.4) and (V.sub.5):
R.sub.4—O-(G.sub.4).sub.1-H  (V.sub.1),
R.sub.4—O-(G.sub.4).sub.2-H  (V.sub.2),
R.sub.4—O-(G.sub.4).sub.3-H  (V.sub.3),
R.sub.4—O-(G.sub.4).sub.4-H  (V.sub.4),
R.sub.4—O-(G.sub.4).sub.s-H  (V.sub.5), in the respective molar proportions a′.sub.1, a′.sub.2, a′.sub.3, a′.sub.4 and a′.sub.5, such that: the sum a′.sub.1+a′.sub.2+a′.sub.3+a′.sub.4+a′.sub.5 is equal to 1, and the sum a′.sub.1+2a′.sub.2+3a′.sub.3+4a′.sub.4+5a′.sub.5 is equal to q.

5. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the composition (C.sub.2) comprises: from 0% to 3% by mass of at least one alcohol of formula (IV):
R.sub.3—OH  (IV) wherein R.sub.3 is as defined in formula (III), and/or from 0% to 3% by mass of at least one alcohol of formula (VI):
R.sub.4—OH  (VI) wherein R.sub.4 is as defined for formula (V).

6. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein, in formulae (I) and (II), the group R.sub.1—C(═O)— represents an acyl radical chosen from octanoyl, decanoyl, dodecanoyl, tetradecanoyl, hexadecanoyl, octadecanoyl, 9-octadecenoyl, 9,12-octadecadienoyl and 9,12,15-octadecatrienoyl radicals.

7. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the composition (C.sub.2) comprises, per 100% of mass: (γ)—a mass proportion of said composition (C.sub.3) of greater than or equal to 14% and less than 70%, and (δ)—a mass proportion of said alcohol of formula (IV) of greater than or equal to 0% and less than or equal to 3%, (ε)—a mass proportion of said composition (C.sub.4) of greater than or equal to 30% and less than or equal to 80%, and (η)—a mass proportion of said alcohol of formula (VI) of greater than or equal to 0% and less than or equal to 3%.

8. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein in formulae (III) and (IV), R.sub.3 represents a linear alkyl radical chosen from n-dodecyl (n-C.sub.12H.sub.25—), n-tetradecyl (n-C.sub.14H.sub.29—) and n-hexadecyl (n-C.sub.16H.sub.32—) radicals.

9. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein, in formulae (V) and (VI), R.sub.4 represents a linear alkyl radical chosen from n-hexyl (n-C.sub.6H.sub.13) and n-heptyl (n-C.sub.7H.sub.15) radicals.

10. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the composition (C.sub.2) comprises a mixture of compositions (C.sub.3) and compositions (C.sub.4), said mixture comprising, per 100% of mass: (γ.sub.1)—from 13.6% to 44.4% by mass of a composition (C.sub.3) represented by formula (III) wherein R.sub.3 represents the (n-C.sub.12H.sub.25) radical, (γ.sub.2)—from 5% to 16.25% by mass of a composition (C.sub.3) represented by formula (III) wherein R.sub.3 represents the n-tetradecyl (n-C.sub.14H.sub.29) radical, and (γ.sub.3)—from 1.4% to 4.55% by mass of a composition (C.sub.3) represented by formula (III) wherein R.sub.3 represents the n-hexadecyl (n-C.sub.16H.sub.32) radical, (ε.sub.1)—from 35% to 80% by mass of a composition (C.sub.4) represented by formula (V) wherein R.sub.4 represents the n-heptyl radical (n-C.sub.7H.sub.15) radical.

11. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein the mass ratio: Δ=Mass of compound(s) of formula (I)/[Mass of composition (C.sub.3)+Mass of composition (C.sub.4)], is greater than or equal to 20/80 and less than or equal to 65/35.

12. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein that the mass ratio: Δ.sub.1=Mass of composition (C.sub.3)/Mass of composition (C.sub.4) is greater than or equal to 20/80 and less than or equal to 70/30.

13. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein at least one gelling agent and/or thickener (AG) is chosen from xanthan gum (G.sub.X), acacia gum exudate (G.sub.A), the mixture of xanthan gum (G.sub.X) and of acacia gum exudate (G.sub.A) in a mass ratio between the xanthan gum (G.sub.X) and the acacia gum exudate (G.sub.A) which is greater than or equal to ⅓ and less than or equal to 3/1.

14. The disinfecting composition (C.sub.D) as claimed in claim 1, wherein at least disinfectant is chosen from the elements of the group consisting of sorbic acid, sodium sorbate, potassium sorbate, dehydroacetic acid, sodium dehydroacetate, benzoic acid, sodium benzoate, potassium benzoate; 1-(2-ethylhexyl) glycerol; hydrogen peroxide; activated peroxides, mixtures of hydrogen peroxide and urea, mixtures of hydrogen peroxide and peracetic acid and mixtures of hydrogen peroxide and iron (Fenton's reagent); hydroperoxycarbonates; peracetic acid; sodium hypochlorite.

15. The disinfecting composition (C.sub.D) as claimed in claim 1, further comprising, per 100% of mass: a)—from 35% to 99.3% water; b)—from 0.5% to 40% by mass of at least one disinfectant chosen from the group consisting of hydrogen peroxide, sodium hypochlorite, potassium sorbate, sodium benzoate, 1-(2-ethylhexyl) glycerol, c)—from 0.1% to 10% by mass of at least one gelling agent and/or thickener (AG) chosen from the elements of the group consisting of xanthan gum (G.sub.X), acacia gum exudate (G.sub.A), the mixture of xanthan gum (G.sub.X) and of acacia gum exudate (G.sub.A) in a mass ratio between the xanthan gum (G.sub.X) and the acacia gum exudate (G.sub.A) which is greater than or equal to ⅓ and less than or equal to 3/1; d)—from 0.1% to 15% by mass of said mixture (M.sub.1) wherein: the compound of formula (I) is chosen from monosodium N-cocoyl glutamate, monopotassium N-cocoyl glutamate, disodium N-cocoyl glutamate and dipotassium N-cocoyl glutamate, the compound of formula (II) is chosen from sodium cocoate and potassium cocoate, in formula (III), R.sub.3 represents a linear or branched, saturated or unsaturated aliphatic radical including from 12 to 16 carbon atoms, G.sub.3 represents a glucose or xylose residue and p represents a decimal number greater than or equal to 1.05 and less than or equal to 2.5; in formula (IV), R.sub.3 represents a linear or branched, saturated or unsaturated aliphatic radical including from 12 to 16 carbon atoms, in formula (V), R.sub.4 represents the n-heptyl (n-C.sub.7H.sub.15) radical, G.sub.4 represents a glucose or xylose residue and q represents a decimal number greater than or equal to 1.05 and less than or equal to 2, in formula (VI), R.sub.4 represents the n-heptyl (n-C.sub.7H.sub.15) radical.

16. A method for disinfectant washing of the hands, comprising providing the disinfecting composition of claim 1, and applying an effective amount of the composition to the hands and washing.

17. A method for treating a skin infection, a skin burn, a scar, a wound, in human beings or animals, comprising applying an effective amount of the composition of claim 1 to skin of the human being or animal in need thereof.

18. The disinfecting composition (C.sub.D) as claimed in claim 2, wherein the composition (C.sub.3) consists of a mixture of compounds represented by formulae (III.sub.1), (III.sub.2), (III.sub.3), (III.sub.4) and (III.sub.5):
R.sub.3—O-(G.sub.3).sub.1-H  (III.sub.1),
R.sub.3—O-(G.sub.3).sub.2-H  (III.sub.2),
R.sub.3—O-(G.sub.3).sub.3-H  (III.sub.3),
R.sub.3—O-(G.sub.3).sub.4-H  (III.sub.4),
R.sub.3—O-(G.sub.3).sub.5-H  (III.sub.5), in the respective molar proportions a.sub.1, a.sub.2, a.sub.3, a.sub.4 and a.sub.5 such that: the sum a.sub.1+a.sub.2+a.sub.3+a.sub.4+a.sub.5 is equal to 1, and the sum a.sub.1+2a.sub.2+3a.sub.3+4a.sub.4+5a.sub.5 is equal to p.

19. The disinfecting composition (C.sub.D) as claimed in claim 2, wherein the composition (C.sub.4) consists of a mixture of compounds represented by formulae (V.sub.1), (V.sub.2), (V.sub.3), (V.sub.4) and (V.sub.5):
R.sub.4—O-(G.sub.4).sub.1-H  (V.sub.1),
R.sub.4—O-(G.sub.4).sub.2-H  (V.sub.2),
R.sub.4—O-(G.sub.4).sub.3-H  (V.sub.3),
R.sub.4—O-(G.sub.4).sub.4-H  (V.sub.4),
R.sub.4—O-(G.sub.4).sub.s-H  (V.sub.5), in the respective molar proportions a′.sub.1, a′.sub.2, a′.sub.3, a′.sub.4 and a′.sub.5, such that: the sum a′.sub.1+a′.sub.2+a′.sub.3+a′.sub.4+a′.sub.5 is equal to 1, and the sum a′.sub.1+2a′.sub.2+3a′.sub.3+4a′.sub.4+5a′.sub.5 is equal to q.

20. The disinfecting composition (C.sub.D) as claimed in claim 3, wherein the composition (C.sub.4) consists of a mixture of compounds represented by formulae (V.sub.1), (V.sub.2), (V.sub.3), (V.sub.4) and (V.sub.5):
R.sub.4—O-(G.sub.4).sub.1-H  (V.sub.1),
R.sub.4—O-(G.sub.4).sub.2-H  (V.sub.2),
R.sub.4—O-(G.sub.4).sub.3-H  (V.sub.3),
R.sub.4—O-(G.sub.4).sub.4-H  (V.sub.4),
R.sub.4—O-(G.sub.4).sub.s-H  (V.sub.5), in the respective molar proportions a′.sub.1, a′.sub.2, a′.sub.3, a′.sub.4 and a′.sub.5, such that: the sum a′.sub.1+a′.sub.2+a′.sub.3+a′.sub.4+a′.sub.5 is equal to 1, and the sum a′.sub.1+.sub.2a′.sub.2+3a′.sub.3+4a′.sub.4+5a′.sub.5 is equal to q.

Description

DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0211] The examples that follow illustrate the invention without, however, limiting it.

1) Preparation of Foaming Compositions

1.1) Preparation of a Solution of Disodium N-Cocoyl Glutamate [Composition (C.SUB.1.)].

[0212] 375 kg of water and 250 kg of monosodium sodium glutamate monohydrate are placed in a reactor, with stirring and at a temperature of 20° C., followed by 184 kg of an aqueous sodium hydroxide solution at 30% by mass so as to reach a pH of 12.245 kg of cocoyl chloride, which is a mixture of acid chlorides comprising, per 100% by mass, 8% by mass of octanoyl chloride, 8% by mass of decanoyl chloride, 50% by mass of lauroyl chloride, 17% by mass of myristoyl chloride, 8% by mass of palmitoyl chloride, 3% by mass of stearoyl chloride, 4% by mass of oleoyl chloride and 2% by mass of linoleoyl chloride, are then added gradually with stirring, followed by a further 140 kg of the 30% sodium hydroxide solution to keep the pH between 11 and 12. The temperature is maintained between 20° C. and 50° C. for 2 hours.

[0213] The mixture obtained is acidified by adding 54 kg of an aqueous sulfuric acid solution at 70% by mass, and is then diluted with 193 kg of water to obtain an aqueous solution of disodium N-cocoyl glutamate [composition (C.sub.1)].

1.2) Analytical Features of the Solutions Prepared Previously

[0214] The analytical features of composition (C.sub.1) are collated in table 1 below.

TABLE-US-00001 TABLE 1 (C.sub.1) Appearance at 20° C. (visual method) Clear Mass content of water (a) (according to the standard 68.00%  NFT 73-201) Residual fatty acids (b) (gas chromatography (GC))  5.8% pH 6.3 Sodium chloride content (potentiometric titration (c)) 3.60% Sodium sulfate content (d) (calculated on feedstock) 5.20% Citrate content (e) (calculated on feedstock)   0% Mass content of active material (AM.sub.1) (cocoyl glutamate) 17.40%  (AM.sub.1) = 100% − (a) − (b) − (c) − (d) − (e)

2) Preparation of the Alkyl Polyglycoside-Based Surfactant Compositions

2.1) Preparation of a Composition (C.SUB.3.)

[0215] 3.7 molar equivalents of a mixture of fatty alcohols (N.sub.1) consisting, per 100% of its mass, of 68% by mass of 1-dodecanol, of 25% by mass of 1-tetradecanol and of 7% by mass of 1-hexadecanol, and then 1 molar equivalent of anhydrous glucose are poured with stirring into a reactor maintained at 80° C., followed by 0.15% by mass of 98% sulfuric acid per 100% by mass of the mixture.

[0216] The reaction medium is placed under a partial vacuum of about 0.18×10.sup.5 Pa (180 mbar) and maintained at 100° C.-105° C. for 4 hours with distillation of the water formed.

[0217] After cooling to 85° C.-90° C. and neutralizing by addition of 40% sodium hydroxide, the reaction medium thus obtained is discharged at 70° C. and filtered to remove the grains of unreacted glucose.

[0218] The filtrate is then poured into another reactor and the excess of the mixture of fatty alcohols (N.sub.1) is removed by distillation using a thin-film evaporator, and the residue is then diluted in water. After stirring for 30 minutes at 50° C., composition (C.sub.3) is obtained, which comprises 50% by mass of water and 50% by mass of a mixture of alkyl polyglucosides (AM.sub.APG1), for which the proportions of alkyl polyglucosides and the mean degree of polymerization of their polyglucoside residue are determined by gas chromatography (GC); it thus comprises, per 100% by mass, 69% by mass of n-dodecyl polyglucosides, 25% by mass of n-tetradecyl polyglucosides and 6% by mass of n-hexacyl polyglucosides with a degree of polymerization equal to 1.25.

2.2) Preparation of a Composition (C.sub.4) Comprising n-Heptyl Polyglucoside

[0219] 2.7 molar equivalents of 1-heptanol and then 1 molar equivalent of anhydrous glucose are poured with stirring into a reactor maintained at 40° C., followed by 0.15% by mass of 98% sulfuric acid per 100% by mass of the mixture.

[0220] The reaction medium is placed under a partial vacuum of about 0.18×10.sup.5 Pa (180 mbar) and maintained at 100° C.-105° C. for 4 hours with distillation of the water formed. After cooling to 85° C.-90° C. and neutralizing by addition of 40% sodium hydroxide, the reaction medium thus obtained is discharged at 70° C. and filtered to remove the grains of unreacted glucose.

[0221] The filtrate is then poured into another reactor and the excess heptanol is distilled off under partial vacuum, and the residue is then diluted in water.

[0222] After stirring for 30 minutes at 50° C., composition (C.sub.4) is obtained comprising 26.4% by mass of water and 73.6% by mass of n-heptyl polyglucosides (AM.sub.APG2), with a degree of polymerization, determined by GC, equal to 1.25.

2.3) Preparation of a Composition (C.sub.5) Comprising n-Octyl Polyglucoside and n-Decyl Polyglucoside

[0223] 2.7 molar equivalents of a mixture of fatty alcohols (N.sub.3) consisting, per 100% of its mass, of 50% by mass of 1-octanol and of 50% by mass of 1-decanol, and then 1 molar equivalent of anhydrous glucose are poured with stirring into a reactor maintained at 80° C., followed by 0.15% by mass of 98% sulfuric acid per 100% by mass of the mixture.

[0224] The reaction medium is placed under a partial vacuum of about 0.18×10.sup.5 Pa (180 mbar) and maintained at 100° C.-105° C. for 4 hours with distillation of the water formed.

[0225] After cooling to 85° C.-90° C. and neutralizing by addition of 40% sodium hydroxide, the reaction medium thus obtained is discharged at 70° C. and filtered to remove the grains of unreacted glucose.

[0226] The filtrate is then poured into another reactor and the excess of the mixture of fatty alcohols (N.sub.3) is removed by distillation using a thin-film evaporator, and the residue is then diluted in water.

[0227] After stirring for 30 minutes at 50° C., composition (C) is obtained, which comprises 40% by mass of water and 60% by mass of a mixture of alkyl polyglucosides (AM.sub.APG3), for which the proportions of alkyl polyglucosides and the mean degree of polymerization of their polyglucoside residue are determined by GC; it thus comprises, per 100% by mass, 52% by mass of n-octyl polyglucoside and 48% by mass of n-decyl polyglucoside, with an average degree of polymerization equal to 1.30.

2.4) Preparation of Compositions Based on Disodium Cocoylglutamate and Alkyl Polylglucosides

[0228] 2.4.1) Preparation of a Composition (T.sub.1) Comprising Disodium N-Cocoylglutamate [Composition (C.sub.1)], a Mixture of n-Dodecyl Polyglucosides, n-Tetradecyl Polyglucosides and n-Hexadecyl Polyglucosides [Composition (C.sub.3)], and n-Heptyl Polyglucoside [Composition (C.sub.4)]

[0229] A composition (T.sub.1) is prepared by pouring, with stirring, the composition (C.sub.1) and the compositions (C.sub.3) and (C.sub.4) into a reactor maintained at 40° C. The mixture is stirred for thirty minutes in order to obtain the composition (T.sub.1). The amounts used are listed in table 2 below.

2.4.2) Preparation of a Composition (T.sub.2) Comprising Disodium N-Cocoylglutamate [Composition (C.sub.1)], a Mixture of n-Dodecyl Polyglucosides, n-Tetradecyl Polyglucosides and n-Hexadecyl Polyglucosides [Composition (C.sub.3)]

[0230] A composition (T.sub.2) is prepared by pouring, with stirring, the composition (C.sub.1) and the composition (C.sub.3) into a reactor maintained at 40° C. The mixture is stirred for thirty minutes in order to obtain the composition (T.sub.2). The amounts used are listed in table 2 below.

TABLE-US-00002 TABLE 2 Amounts used (C.sub.1) (C.sub.3) (C.sub.4) (T.sub.1) 74.9 g 11.1 g 14.0 g (T.sub.2) 93.0 g 7.0 g 0 g
The analytical features of the compositions (T.sub.1) and (T.sub.2) are collated in table 3 below.

TABLE-US-00003 TABLE 3 H.sub.2O AMC.sup.(5) FA.sup.(1) Δ.sup.(2) T′.sup.(3) (%) Δ.sub.1.sup.(4) as % Appearance (T.sub.1) 5.84% 0.45 0.55 60.15% 0.54 28.85% Homogeneous (T.sub.2) 5.4% 4.6 0.18 66.74% — 19.68% Homogeneous .sup.(1)Residual fatty acids (mass percentage) .sup.(2)Δ = (AM.sub.1)/[(AM.sub.APG1) + (AM.sub.APG2)] .sup.(3)T′ = [(AM.sub.APG1) + (AM.sub.APG2)]/[(AM.sub.1) + (AM.sub.APG1) + (AM.sub.APG2)] .sup.(4)Δ.sub.1 = (AM.sub.APG1)/(AM.sub.APG2) .sup.(5)AMC = [(AM.sub.1) + (AM.sub.APG1) + (AM.sub.APG2)]/total mass, with total mass = 100 g.

3) Preparation of Compositions According to the Invention and of Comparative Compositions

[0231] 3.1) Preparation of Compositions According to the Invention E.sub.1 to E.sub.8 and of a Comparative Composition E.sub.0

[0232] The compositions E.sub.0 to E.sub.8 are prepared at a temperature of 25° C., in a reactor of suitable volume fitted with anchor-type mechanical stirring at a speed of 50 revolutions.Math.min.sup.−1. The ingredients are gradually introduced one after the other until a homogeneous and liquid composition is obtained.

[0233] The compositions are described in detail in table 4 below:

TABLE-US-00004 TABLE 4 E.sub.0 E.sub.1 E.sub.2 E.sub.3 E.sub.4 Composition 2.36%, i.e. 2.36%, i.e. 2.36%, i.e. 2.36%, i.e. 2.36%, i.e. (T.sub.1) at 0.68% of 0.68% of 0.68% of 0.68% of 0.68% of 28.85% of AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) Xanthan 15% 15% 15% 15% 15% solution at 1.66% by mass Deionized q.s. 100% q.s. 100% q.s. 100% q.s. 100% q.s. 100% water Bleach at — 7.1% by 21.4% by — — 12° mass of mass of chlorine NaOCl NaOCl Aqueous — — — 3.3% by 16.7% by hydrogen mass of mass of peroxide H.sub.2O.sub.2 H.sub.2O.sub.2 solution at 35% by mass pH product 6.5 6.4 6.7 6.4 6.2 Visual Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid liquid product

TABLE-US-00005 TABLE 4 (a) E.sub.5 E.sub.6 E.sub.7 E.sub.8 Composition 2.36%, i.e. 2.36%, i.e. 2.36%, i.e. 2.36%, i.e. (T.sub.1) at 28.5% of 0.68% of 0.68% of 0.68% of 0.68% of AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) Xanthan solution 15% 15% 15% 15% at 1.66% by mass Deionized water q.s. 100% q.s. 100% q.s. 100% q.s. 100% Euxyl ™K712.sup.(6)  5% 10% — — Euxyl ™K903.sup.(7) — — 2.5%  — Euxyl ™PE9010.sup.(8) — — — 2.5%  pH product 6.5 6.4 6.5 6.5 Visual Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid product .sup.(6)Euxyl ™K712: aqueous solution containing 45% of active material, said active material comprising, per 100% of its mass, 33% by mass of potassium sorbate and 67% by mass of sodium benzoate. .sup.(7)Euxyl ™ K903: mixture of benzyl alcohol, benzoic acid, dehydroacetic acid and tocopherol. .sup.(8)Euxyl ™ PE9010: mixture of 2-phenoxyethanol and 1-(2-ethylhexyl) glycerol
3.2) Preparation of Comparative Compositions F.sub.0 to F.sub.4, Comprising the Composition (T.sub.2)

[0234] The compositions F.sub.0 to F.sub.4 are prepared according to the procedure described in section 3.1 above.

[0235] The compositions F.sub.0 to F.sub.4 are described in detail in table 5 below:

TABLE-US-00006 TABLE 5 F.sub.0 F.sub.1 F.sub.2 F.sub.3 F.sub.4 Composition 3.45%, i.e. 3.45%, i.e. 3.45%, i.e. 3.45%, i.e. 3.45%, i.e. (T.sub.2) at 0.68% of 0.68% of 0.68% of 0.68% of 0.68% of 19.68% of AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) AMC.sup.(5) Xanthan 15% 15% 15% 15% 15% solution at 1.66% by mass Deionized q.s. 100% q.s. 100% q.s. 100% q.s. 100% q.s. 100% water Bleach at — 7.1% by 21.4% by — — 12° mass of mass of chlorine NaOCl NaOCl Aqueous — — — 3.3% by 16.7% by hydrogen mass of mass of peroxide H.sub.2O.sub.2 H.sub.2O.sub.2 solution at 35% by mass pH product 6.4 6.4 6.5 6.2 6.0 Visual Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid liquid product
3.3) Preparation of Comparative Compositions F.sub.5 to F.sub.9, Comprising the Composition (C.sub.1)

[0236] The compositions F.sub.5 to F.sub.9 are prepared according to the procedure described in section 3.1 above.

[0237] The compositions F.sub.5 to F.sub.9 are described in detail in table 6 below:

TABLE-US-00007 TABLE 6 F.sub.5 F.sub.6 F.sub.7 F.sub.8 F.sub.9 Composition 3.90%, i.e. 3.90%, i.e. 3.90%, i.e. 3.90%, i.e. 3.90%, i.e. (C.sub.1) at 0.68% of 0.68% of 0.68% of 0.68% of 0.68% of 17.4% of AM1 AM1 AM1 AM1 AM1 AM1 Xanthan 15% 15% 15% 15% 15% solution at 1.66% by mass Deionized q.s. 100% q.s. 100% q.s. 100% q.s. 100% q.s. 100% water Bleach at — 7.1% by 21.4% by — — 12° mass of mass of chlorine NaOCl NaOCl Aqueous — — — 3.3% by 16.7% by hydrogen mass of mass of peroxide H.sub.2O.sub.2 H.sub.2O.sub.2 solution at 35% by mass pH product 6.3 6.8 6.7 6.5 6.2 Visual Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid liquid product
3.4) Preparation of Comparative Compositions F.sub.10 to F.sub.14, Comprising the Composition (C.sub.3)

[0238] The compositions F.sub.10 to F.sub.14 are prepared according to the procedure described in section 3.1 above.

[0239] The compositions F.sub.10 to F.sub.14 are described in detail in table 7 below:

TABLE-US-00008 TABLE 7 F.sub.10 F.sub.11 F.sub.12 F.sub.13 F.sub.14 Composition 1.36%, i.e. 1.36%, i.e. 1.36%, i.e. 1.36%, i.e. 1.36%, i.e. (C.sub.3) at 0.68% of 0.68% of 0.68% of 0.68% of 0.68% of 50.0% of AM.sub.APG1 AM.sub.APG1 AM.sub.APG1 AM.sub.APG1 AM.sub.APG1 AM.sub.APG1 Xanthan 15% 15% 15% 15% 15% solution at 1.66% by mass Deionized q.s. 100% q.s. 100% q.s. 100% q.s. 100% q.s. 100% water Bleach at — 7.1% by 21.4% by — — 12° mass of mass of chlorine NaOCl NaOCl Aqueous — — — 3.3% by 16.7% by hydrogen mass of mass of peroxide H.sub.2O.sub.2 H.sub.2O.sub.2 solution at 35% by mass pH product 6.4 6.6 6.8 6.9 6.1 Visual Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid liquid product
3.5) Preparation of Comparative Compositions F.sub.15 to F.sub.19, Comprising the Composition (C.sub.4)

[0240] The compositions F.sub.15 to F.sub.19 are prepared according to the procedure described in section 3.1 above.

[0241] The compositions F.sub.15 to F.sub.19 are described in detail in table 8 below:

TABLE-US-00009 TABLE 8 F.sub.15 F.sub.16 F.sub.17 F.sub.18 F.sub.19 Composition 0.92%, i.e. 0.92%, i.e. 0.92%, i.e. 0.92%, i.e. 0.92%, i.e. (C.sub.4) at 0.68% of 0.68% of 0.68% of 0.68% of 0.68% of 73.6% of AM.sub.APG2 AM.sub.APG2 AM.sub.APG2 AM.sub.APG2 AM.sub.APG2 AM.sub.APG2 Xanthan 15% 15% 15% 15% 15% solution at 1.66% by mass Deionized q.s. 100% q.s. 100% q.s. 100% q.s. 100% q.s. 100% water Bleach at — 7.1% by 21.4% by — — 12° mass of mass of chlorine NaOCl NaOCl Aqueous — — — 3.3% by 16.7% by hydrogen mass of mass of peroxide H.sub.2O.sub.2 H.sub.2O.sub.2 solution at 35% by mass pH product 6.3 6.5 6.5 6.4 6.5 Visual Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid liquid product
3.6) Preparation of Comparative Compositions F.sub.20 to F.sub.24, Comprising the Composition (C.sub.4)

[0242] The compositions F.sub.20 to F.sub.24 are prepared according to the procedure described in section 3.1 above.

[0243] The compositions F.sub.20 to F.sub.24 are described in detail in table 9 below:

TABLE-US-00010 TABLE 9 F.sub.20 F.sub.21 F.sub.22 F.sub.23 F.sub.24 Composition 1.13%, i.e. 1.13%, i.e. 1.13%, i.e. 1.13%, i.e. 1.13%, i.e. (C.sub.5) at 0.68% of 0.68% of 0.68% of 0.68% of 0.68% of 60.0% of AM.sub.APG3 AM.sub.APG3 AM.sub.APG3 AM.sub.APG3 AM.sub.APG3 AM.sub.APG3 Xanthan 15% 15% 15% 15% 15% solution at 1.66% by mass Deionized q.s. 100% q.s. 100% q.s. 100% q.s. 100% q.s. 100% water Bleach at — 7.1% by 21.4% by — — 12° mass of mass of chlorine NaOCl NaOCl Aqueous — — — 3.3% by 16.7% by hydrogen mass of mass of peroxide H.sub.2O.sub.2 H.sub.2O.sub.2 solution at 35% by mass pH product 6.8 6.4 6.0 6.2 6.0 Visual Homogeneous Homogeneous Homogeneous Homogeneous Homogeneous appearance liquid liquid liquid liquid liquid product

4) Evaluation of the Foaming Properties

4.1) Principle of the Evaluation Method

[0244] The evaluation of the foaming properties of the test compositions is performed by forming a foam, from a solution of WHO hard water comprising a predetermined mass content of the test compositions, by mechanical stirring at a temperature of 20° C.

[0245] 4.2) Experimental Protocol

[0246] 250 cm.sup.3 aqueous solutions are prepared so as to obtain solutions at 0.5% by mass of surfactant active material in WHO hard water, from the compositions E.sub.0 to E.sub.4, and F.sub.0 to F.sub.24, as described above.

[0247] The WHO hard water contains, per liter of deionized water, 0.403 g of anhydrous calcium chloride and 0.139 g of magnesium chloride hexahydrate; which gives it a hardness titer equal to 34°Th.

[0248] These solutions are poured into a 500 cm.sup.3 beaker and are then stirred using a Rayneri™ laboratory blender (model 33/300) equipped with a butterfly paddle with three hollow arms, at a constant speed of 3000 rpm for 2 minutes.

4.3) Expression of the Results

[0249] The following parameters are measured for each test: [0250] The expansion time (T.sub.exp.): this is the stirring time after which suppression of the vortex in the beaker is observed. Beyond this time, the foam totally surrounds the shaft of the paddle and its level is horizontal; [0251] The half-life time (T.sub.1/2): this is the time after which the foam obtained from a certain volume of foaming solution became drained of an amount of solution corresponding to half of the initial volume. For this test, the half-life time is reached when the upper level of the draining water reaches the 125 cm.sup.3 mark on the beaker; [0252] The height of foam generated by stirring (H.sub.t0): this is the height of foam generated at the end of the 2 minutes of stirring; [0253] The residual foam height after 30 minutes (H.sub.t30): this is the foam height observed 30 minutes after the end of the 2 minutes of stirring. [0254] The difference Δ.sub.H=(H.sub.t0−H.sub.t30), makes it possible to evaluate comparatively the quality of the foams generated by the various surfactants.

4.4) Results Obtained

[0255] The results obtained for the aqueous solutions of active material in WHO hard water for the compositions of the compositions E.sub.0 to E.sub.6, and F.sub.0 to F.sub.24 are shown in tables 10 to 15 below.

TABLE-US-00011 TABLE 10 (T.sub.exp) (T.sub.1/2) (H.sub.t0) (H.sub.t30) (ΔH) E.sub.0 18 s >240 min 125 mm 120 mm 5 mm E.sub.1 7 s >240 min 140 mm 130 mm 10 mm E.sub.2 6 s >240 min 140 mm 130 mm 10 mm E.sub.3 17 s >240 min 140 mm 130 mm 10 mm E.sub.4 22 s >240 min 140 mm 130 mm 10 mm E.sub.5 6 s >240 min 132 mm 130 mm 2 mm E.sub.6 8 s >240 min 134 mm 134 mm 0 mm E.sub.7 10 s 155 min 140 mm 125 mm 15 mm E.sub.8 16 s 120 min 152 mm 130 mm 22 mm

TABLE-US-00012 TABLE 11 (T.sub.exp) (T.sub.1/2) (H.sub.t0) (H.sub.t30) (ΔH) F.sub.0 12 s >240 min <100 mm <100 mm — F.sub.1 8 s >240 min <100 mm <100 mm — F.sub.2 9 s 150 min <100 mm <100 mm — F.sub.3 9 s >240 min <100 mm <100 mm — F.sub.4 8 s >240 min <100 mm <100 mm —

TABLE-US-00013 TABLE 12 (T.sub.exp) (T.sub.1/2) (H.sub.t0) (H.sub.t30) (ΔH) F.sub.5 >120 s >240 min 80 mm <80 mm — F.sub.6 35 s >240 min 110 mm <100 mm — F.sub.7 >120 s >240 min <100 mm <100 mm — F.sub.8 >120 s >240 min <100 mm <100 mm — F.sub.9 >120 s >240 min <100 mm <100 mm —

TABLE-US-00014 TABLE 13 (T.sub.exp) (T.sub.1/2) (H.sub.t0) (H.sub.t30) (ΔH) F.sub.10 >120 s >240 min <100 mm <100 mm — F.sub.11 35 s >240 min <100 mm <100 mm — F.sub.12 >120 s >240 min <100 mm <100 mm — F.sub.13 >120 s >240 min <100 mm <100 mm — F.sub.14 >120 s >240 min <100 mm <100 mm —

TABLE-US-00015 TABLE 14 (T.sub.exp) (T.sub.1/2) (H.sub.t0) (H.sub.t30) (ΔH) F.sub.15 50 s >240 min 90 mm 65 mm 25 mm F.sub.16 >120 s >240 min <100 mm <100 mm — F.sub.17 >120 s >240 min <100 mm <100 mm — F.sub.18 80 s 180 min 80 mm 55 mm 25 mm F.sub.19 60 s 180 min 75 mm 50 mm 25 mm

TABLE-US-00016 TABLE 15 (T.sub.exp) (T.sub.1/2) (H.sub.t0) (H.sub.t30) (ΔH) F.sub.20 7 s 180 min 138 mm 126 mm 12 mm F.sub.21 4 s 120 min 144 mm 129 mm 15 mm F.sub.22 5 s 105 min 144 mm 128 mm 16 mm F.sub.23 6 s 140 min 135 mm 125 mm 10 mm F.sub.24 4 s 20 min 168 mm 160 mm 25 mm

4.5) Analyses of the Results

[0256] These results show that the compositions E.sub.1 to E.sub.6 according to the invention make it possible to prepare foams having all the qualities required to be used in a process for decontaminating hard surfaces, because they are generated rapidly, in a sufficient volume (>100 mm), and stable (with a half-life of over four hours).