DISPOSABLE DELIVERY ASSEMBLY FOR A DRUG DELIVERY DEVICE

Abstract

The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising: a disposable injector comprising an injection needle, a flexible tube and an injector fluid coupling, wherein the injection needle is in fluid communication with the fluid coupling via the flexible tube, a disposable cartridge comprising a reservoir at least partially filled with the liquid medicament and comprising a cartridge fluid coupling in fluid communication with the reservoir, wherein the injector and the cartridge are mechanically interconnected in an undeployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are disconnected, and wherein the cartridge is displaceable relative to the injector into a deployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are in fluid communication.

Claims

1. A disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the disposable delivery assembly comprising: a disposable injector comprising an injection needle, a flexible tube, and an injector fluid coupling, wherein the injection needle is in fluid communication with the injector fluid coupling via the flexible tube; and a disposable cartridge comprising a reservoir at least partially filled with the liquid medicament and comprising a cartridge fluid coupling in fluid communication with the reservoir, wherein the disposable injector and the disposable cartridge are mechanically interconnected in an undeployed configuration, in which the injector fluid coupling and the disposable cartridge fluid coupling are disconnected, and wherein the disposable cartridge is configured to be displaced relative to the disposable injector into a deployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are in fluid communication.

2. The disposable delivery assembly according to claim 1, wherein the disposable cartridge and the disposable injector are pre-assembled by mechanically attaching the disposable cartridge to the disposable injector, and wherein a pre-assembly of the disposable cartridge and the disposable injector is insertable into a receptacle of a housing of the drug delivery device only when the disposable injector and the disposable cartridge are in the undeployed configuration.

3. The disposable delivery assembly according to claim 1 consisting of the disposable cartridge and the disposable injector, and wherein the disposable injector and the disposable cartridge are directly mechanically connected when in the undeployed configuration.

4. The disposable delivery assembly according to claim 1, wherein one of the disposable cartridge and the disposable injector comprises at least one stop member engaging with a correspondingly shaped stop face of the other one of the disposable cartridge and the disposable injector to impede self-acting displacement of the disposable cartridge and the disposable injector from the undeployed configuration into the deployed configuration.

5. The disposable delivery assembly according to claim 4, wherein the stop member and the stop face provide an interlock operable to prevent transferring of the disposable cartridge and the disposable injector into the deployed configuration.

6. The disposable delivery assembly of claim 4, wherein a mutual abutment and engagement of the stop member and the stop face is, at least temporally, suspendable by a decoupler of a fastener of the drug delivery device.

7. The disposable delivery assembly of claim 6, wherein the fastener is configured to releasably fix the disposable delivery assembly in or at a receptacle of the drug delivery device.

8. The disposable delivery assembly of claim 6, wherein the fastener is transferable from a release configuration into a locking configuration thereby inducing a displacement of the disposable cartridge relative to the disposable injector into the deployed configuration.

9. The disposable delivery assembly according to claim 1, wherein one of the disposable cartridge and the disposable injector comprises a linear guiding configured to engage with a guide section of the other one of the disposable cartridge and the disposable injector.

10. The disposable delivery assembly according to claim 9, wherein the injector fluid coupling comprises a cannula extending parallel to the linear guiding and configured to penetrate a pierceable seal of the cartridge fluid coupling.

11. A drug delivery device for dispensing a liquid medicament, comprising: a housing having at least one feeder member; a receptacle to receive a disposable delivery assembly, the disposable delivery assembly comprising: a disposable injector comprising an injection needle, a flexible tube, and an injector fluid coupling, wherein the injection needle is in fluid communication with the fluid coupling via the flexible tube, and a disposable cartridge comprising a reservoir at least partially filled with the liquid medicament and comprising a cartridge fluid coupling in fluid communication with the reservoir, wherein the disposable injector and the disposable cartridge are mechanically interconnected in an undeployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are disconnected, and wherein the disposable cartridge is configured to be displaced relative to the disposable injector into a deployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are in fluid communication; and a fastener configured to releasably fix the disposable delivery assembly in or relative to the receptacle.

12. The drug delivery device according to claim 11, wherein the receptacle is configured to receive the disposable delivery assembly only when the disposable injector and the disposable cartridge are in the undeployed configuration.

13. The drug delivery device according to claim 11, wherein the fastener is operably engageable with at least one of the disposable cartridge and the disposable injector and wherein the fastener is configurable from a release configuration into a locking configuration to mutually displace the disposable cartridge and the disposable injector into the deployed configuration.

14. The drug delivery device according to claim 11, wherein the fastener is pivotably connected to the housing between an opened configuration and a closed configuration, wherein the receptacle is accessible in the opened configuration and wherein the receptacle is at least partially covered by the fastener in the closed configuration.

15. The drug delivery device according to claim 14, wherein the fastener comprises a base portion pivot mounted to the housing and wherein the base portion comprises a rear panel that extends radially from a pivot axis into the receptacle upon the fastener pivoting from the closed configuration towards the opened configuration.

16. The drug delivery device according to claim 14, wherein the fastener comprises a decoupler configured to engage with at least one of a stop member and a stop face of the disposable injector and the disposable cartridge when the fastener reaches the closed configuration.

17. The drug delivery device according to claim 13, wherein the fastener comprises a slider and wherein the fastener is configured to be transferred from the release configuration into the locking configuration by slidably displacing the slider from an extended position into a retracted position.

18. The drug delivery device according to claim 17, wherein the fastener comprises a pivotable lid with a free end formed by the slider, wherein in closed configuration of the fastener, the slider at least partially enclosing the cartridge is configured to be retracted from the extended position into the retracted position along the deploy direction, thereby displacing the cartridge relative to the injector into the deployed configuration.

19. A method of deploying or undeploying a disposable delivery assembly of a drug delivery device, the method comprising: positioning the disposable delivery assembly against the drug delivery device, the disposable delivery assembly comprising: a disposable injector comprising an injection needle, a flexible tube, and an injector fluid coupling, wherein the injection needle is in fluid communication with the injector fluid coupling via the flexible tube, and a disposable cartridge comprising a reservoir at least partially filled with the liquid medicament and comprising a cartridge fluid coupling in fluid communication with the reservoir, wherein the disposable injector and the disposable cartridge are mechanically interconnected in an undeployed configuration, in which the injector fluid coupling and the disposable cartridge fluid coupling are disconnected, and wherein the disposable cartridge is configured to be displaced relative to the disposable injector into a deployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are in fluid communication; inserting a pre-assembly of the disposable cartridge and the disposable injector, in which the disposable cartridge and the disposable injector are in the undeployed configuration, in a receptacle of a housing of the drug delivery device; and transferring a fastener of the drug delivery device from a released configuration into a locking configuration thereby inducing a displacement of the disposable cartridge relative to the disposable injector into the deployed configuration.

20. The method of claim 19, further comprising transferring the fastener from the locking configuration into the release configuration thereby inducing a displacement of the disposable cartridge relative to the disposable injector into the undeployed configuration.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0064] In the following an embodiment of the disposable delivery assembly in connection with a drug delivery device is described in more detail by making reference to the drawings, in which:

[0065] FIG. 1 schematically shows the drug delivery device in a perspective view with the fastener in closed and retracted position,

[0066] FIG. 2 shows the drug delivery device with the fastener in opened and extended configuration,

[0067] FIG. 3 shows the disposable delivery assembly during insertion into the receptacle of the drug delivery device,

[0068] FIG. 4 shows a perspective view of the drug delivery device with the disposable delivery assembly assembled thereto,

[0069] FIG. 5 shows the drug delivery device with the fastener in closed but extended configuration,

[0070] FIG. 6 is an isolated perspective and exploded view of the disposable delivery assembly with disassembled disposable injector and disposable cartridge,

[0071] FIG. 7 shows the disposable injector in a perspective view,

[0072] FIG. 8 shows a cross-section through the disposable injector in an initial configuration and

[0073] FIG. 9 shows the injector according to FIG. 8 with an extended injection needle,

[0074] FIG. 10 shows the cartridge in an isolated perspective view,

[0075] FIG. 11 shows the cartridge according to FIG. 10 in an exploded view,

[0076] FIG. 12 shows the cartridge in longitudinal cross-section,

[0077] FIG. 13 shows a side view of disassembled disposable injector and disposable cartridge,

[0078] FIG. 14a shows the disposable delivery assembly in undeployed configuration,

[0079] FIG. 14b shows the delivery assembly during a release of the interlock of stop member and stop face,

[0080] FIG. 14c shows the disposable delivery assembly in a deployed configuration,

[0081] FIG. 15a shows a cross-section through the delivery assembly according to FIG. 14a and

[0082] FIG. 15b shows the disposable delivery assembly in cross-section in the deployed configuration according to FIG. 14c,

[0083] FIG. 16 shows a partial cross-section of the drug delivery device with the fastener in closed but extended configuration,

[0084] FIG. 17 is a cross-section through the drug delivery device,

[0085] FIG. 18 shows an isolated side view of the interaction between the fastener's rear panel and the cartridge during an opening movement,

[0086] FIG. 19 shows an exploded view of the various components of the fastener,

[0087] FIG. 20 shows a cross-section through the fastener in retracted configuration and

[0088] FIG. 21 shows the fastener in the extended, hence in the release configuration.

DETAILED DESCRIPTION

[0089] The drug delivery device 10 as it is illustrated in FIGS. 1-5 comprises a housing 12 featuring a receptacle 20 which is closeable by a fastener 14 that serves as a lid 15 for the receptacle 20. The fastener 14 is pivot mounted to the housing 12 by means of a hinge 16. Consequently, the fastener 14 is pivotable between a closed configuration 14d as shown in FIGS. 1 and 5 and an opened configuration 14c as illustrated in FIGS. 2-4. In the opened configuration 14c, the receptacle 20 is accessible from outside to insert a disposable delivery assembly 50 as for instance illustrated in FIG. 3. The delivery assembly 50 is insertable into the receptacle 20 along an insert direction 2 as illustrated in FIG. 3.

[0090] The disposable delivery assembly 50 comprises a disposable injector 60 as illustrated in FIGS. 7-9 and further comprises a disposable cartridge 70 as shown in FIGS. 10-12. Disposable injector 60 and disposable cartridge 70 are mechanically interconnected in an undeployed configuration 4 as for instance shown in FIGS. 14a and 15a. In this configuration disposable injector 60 and disposable cartridge 70 are mechanically engaged and connected but are not yet in fluid communication. A fluid communication is yet to be established upon transferring the fastener 14 from a release configuration 14a as shown in FIG. 5 into a locking configuration 14b as shown in FIG. 1.

[0091] The disposable injector as shown in FIG. 7 comprises a base 61. The base features a track 63 through which a flexible tube 64 is guided. In the region of the track 63 the feeder member 100 or the pump head of the drug delivery device 10 engages with the flexible tube 64. Here, the flexible tube 64 is squeezed by the feeder member 100 in order to transport the liquid medicament from the reservoir 80 of the cartridge 70 towards an injection needle 65 of the injector 60. The injection needle 65 is also a component of the injector 60. As can be seen from a comparison of FIGS. 8 and 9, the injection needle 65 is attached to a piston 66, which is slideably received in a conduct 67. An outlet of the conduct 67 is covered by a protector 67a as shown in FIG. 8. Upon activation of the injector 60 the protector 67a typically in form of an adhesive foil is to be removed, hence allowing the piston 66 to slide along the conduct 67 thereby advancing the injection needle 65 into an extended position as illustrated in FIG. 9.

[0092] Typically, when arranged in the receptacle 20 of the drug delivery device 10 that side face of the injector 60 featuring the outlet for the injection needle 65 forms an integral component of the outer surface or housing 12 of the drug delivery device 10. In typical application scenarios, the drug delivery device 10 is e.g. adhesively attached to the skin of a patient. Upon activation of the injector 60, hence upon activation of the drug delivery device 10 the injection needle 65 is automatically positioned into the extended position thereby piercing or penetrating dermal tissue for transdermal or subcutaneous injection of the liquid medicament.

[0093] Opposite the injection needle 65 the injector 60 comprises an injector fluid coupling 68, presently in form of a hollow but tipped cannula 68a. As becomes apparent from FIGS. 8 and 9, the injector fluid coupling 68 extends from a sidewall of the injector's base 61. The tipped injector fluid coupling 68 serves to penetrate and to pierce a cartridge fluid coupling 90 as for instance illustrated in FIG. 12. The cartridge fluid coupling 90 comprises a pierceable seal 82, typically in form of a sealing disc. The pierceable seal 82 closes a fluid channel 86 which is in fluid communication with the interior of a reservoir 80 containing the liquid medicament. The reservoir 80 comprises a flexible bag 81 which allows and supports a suction-based withdrawal of a medicament therefrom. The outlet of the fluid channel 86 is closed by the pierceable seal 82, which is secured within an opening of a base of the cartridge 70 by means of an insert 84. The insert 84 comprises a central through opening 85 which allows to receive the tipped injector fluid coupling 68, hence the cannula 68a. The pierceable seal 82 typically serves as a septum of elastic material, which may even be pierced multiple times without exhibiting substantial leakage.

[0094] The cartridge 70 features a base 74 having and forming a fluid channel 86 and further has a housing 71 providing a protective sheath for the flexible bag 81 forming the reservoir 80 for the liquid medicament.

[0095] The base 74 further comprises a socket 76 extending from a planar surface of the base 74. The socket 76 extends into the flexible bag 81 so as to close an opening of the flexible bag. In addition and in order to seal the interconnection of flexible bag 81 and the socket 76, the socket comprises an annular or surrounding groove 78 at its outer circumference. In addition and as becomes apparent from FIG. 12, the housing 71 features a receptacle to engage with the socket 76 in a press fit. Here, the housing 71 extends over and all around the socket 76 and an O-ring 77 located in the socket's groove 78, thereby squeezing and fixing the flexible bag 81 therebetween.

[0096] In this way, a sealed interconnection of socket 76 and flexible bag 81 can be provided without any adhesives and without application of thermal energy. By having a press fit arrangement of the flexible bag 81 with the socket 76 a rather medicament friendly seal can be provided.

[0097] The fluid channel 86 extends from a middle portion of the socket's 76 front face 75 into the base 74. As shown in FIG. 12, the fluid channel 86 extends substantially horizontal and then vertically upwardly before it merges and extends into an outlet section that is sealed by the pierceable seal 82. The outlet section forming the cartridge fluid coupling 90 is arranged and oriented substantially parallel to the lower portion of the fluid channel 86 which is in extension of the reservoir 80 and parallel to a linear guiding 72 as will be explained below. In this way, the pierceable seal 82 can be pierced and penetrated by the injector fluid coupling 68, hence by its cannula 68a. At an upper portion of the vertical segment of the fluid channel 86 there is located a closure 88 that may serve as a ventilation. The closure 88 may be removable to eventually refill the reservoir 80 by a refill- or retail service. The insert 84 that keeps the pierceable seal 82 in position may comprise an outer thread to engage with an inner thread of a corresponding opening of the base 74. Alternatively, the insert 84 is press fitted or squeezed in the base 74.

[0098] As it is further illustrated in Fig. lithe front face 75 of the socket 76 comprises several grooves 79 that extend across the front face 75 towards the outer circumference or to the outer edge thereof. All these grooves 79 merge with the central fluid channel 86. Since the flexible bag 81 is of flexible material it is conceivable that a portion thereof may get in abutment with a portion of the front face 75 when extracting the liquid medicament from the reservoir 80. Here, the grooves 79 provide a respectable fluid flow even in case that the portion of the front face 75 coinciding with the fluid channel 86 should be obstructed or should get in abutment with an inside-facing portion of the flexible bag 81.

[0099] The housing 71 of the cartridge 70 further comprises a linear guiding 72, e.g. in form of a longitudinal groove as illustrated for instance in FIG. 10. The linear guiding 72 cooperates and engages with a guide section 59 of the injector as illustrated in FIG. 6. In this way, cartridge 70 and injector 60 can be mechanically connected in a well-defined way but undeployed configuration, in which the cannula 68a of the injector 60 does not yet penetrate or pierce the pierceable seal 82 of the cartridge 70. The linear guiding 72 further supports and defines a mutual linear and straight displacement of the disposable injector 60 relative to the cartridge 70. Hence, the cartridge 70 may be displaced along the linear guiding 72 with regard to the injector 60 being fixed in the housing 20.

[0100] In an initial and undeployed configuration 4 as illustrated in FIG. 14a, the injector 60 and the cartridge 70 are mutually assembled in such a way, that the stop member 69 protruding from a sidewall portion of the injector 60 is in abutment with a corresponding stop face 73a of the cartridge 70. The linear guiding 72 provided as a linearly and rather straight extending groove at a sidewall portion of the housing 71 features a recess 73 formed by a beveled portion of the linear guiding. As shown for instance in FIG. 14a, the stop member 69 of the injector 60 comprises a shape that corresponds to the beveled recess 73.

[0101] Consequently, when reaching the undeployed configuration 4 as shown in FIG. 14a, the flexible deformable stop member 69 enters the beveled recess 73 of the linear guiding 72 and abuts with the vertically-extending stop face 73a of the cartridge 70. In this way, any further displacement of the disposable cartridge 70 towards the left hand side, hence towards the disposable injector 60 is impeded and prevented. It is only upon interaction with a decoupler 37 of the drug delivery device's 10 fastener 14 that the interlock between injector 60 and cartridge 70 can be abrogated or suspended.

[0102] The decoupler 37 may be simply provided by or integrated into a sidewall portion 38 of the lid-shaped fastener 14. As illustrated in FIG. 16 and when reaching a closed configuration 14d the pivotable or flexible deformable stop member 69 is pressed downwards so to leave the recess 73 of the cartridge 70, thereby allowing that the cartridge 70 can be further displaced towards the deploy direction 1 until it reaches the deployed configuration 6 as illustrated in FIG. 14c.

[0103] Comparing of FIGS. 15a and 15b, each of which illustrating the disposable delivery assembly 50 in undeployed configuration 4 and in deployed configuration 6, respectively, reveals that only in the deployed configuration 6 the cannula 68a penetrates the pierceable seal 82 of the cartridge thereby providing and establishing a fluid communication between the reservoir 80 and the injection needle 65.

[0104] Due to the interaction of the stop member 69 with the correspondingly-shaped stop face 73a a premature fluid transferring coupling of injector 60 and cartridge 70 can be effectively prevented. When commercially distributed by a manufacturer, disposable injector 60 and disposable cartridge 70 may be provided as a preassembled disposable delivery assembly 50 as shown in FIGS. 3 and 14a. Deployment of injector and cartridge, hence establishing of a fluid transferring interconnection of injector 60 and cartridge 70 may only take place through interaction with the fastener 14 of the drug delivery device 10.

[0105] In the same way also a disconnecting and decoupling of disposable cartridge 70 and disposable injector 60 after consumption of the medicament the interaction with the fastener 14 upon opening the receptacle 20 may provide a self-acting and automated disconnection of cartridge 70 and injector 60. Contamination of the environment by droplets of the medicament rinsing out of the injection needle 65 can therefore be effectively avoided. Also here it is conceivable that cartridge 70 and injector 60 comprises mutually corresponding tamper proof members, which serve to avoid reconnection or redeployment of cartridge 70 and injector 60 once they have been transferred from the deployed configuration 6 back into the undeployed configuration 4.

[0106] The drug delivery device 10 as for instance illustrated in FIG. 17 is designed and implemented as a peristaltic pump. It comprises a feeder member 100, presently in form of a rotatable pump head that engages with the flexible tube 64 in order to squeeze the same for drug delivery. In addition, the drug delivery device 10 comprises an energy source, typically in form of an electric battery 102. Moreover, it comprises an injection drive 104 by way of which the injection needle 65 can be displaced along the conduct 67. By means of the injection drive 104 the injection needle 65 can be displaced from an initial position into an extended position as shown in FIG. 9. In the same way the injection drive 104 may serve to retract the extended injection needle 65. Additionally, the peristaltic pump 10 comprises a delivery drive 106 in order to set the pump head, hence the feeder member 100 in rotation during and for drug delivery.

[0107] In the present embodiment the complete disposable delivery assembly 50 is insertable along an insert direction 2 into the opened receptacle 20 as indicated in FIG. 3. The sidewall 21 of the receptacle 20, which belongs to the housing 12 of the drug delivery device 10 comprises a recessed structure 22, e.g. in form of a groove extending parallel to the insert direction 2. It is the injector 60 that comprises a correspondingly-shaped mating structure 62 as for instance shown in FIGS. 7 and 8. By inserting the injector 60 with the outwardly-extending protrusion 62 into the grooves 22 of the receptacle 20, only the disposable injector 60 of the delivery assembly 50 can be secured and fixed to the housing 12 of the drug delivery device 10 in regard to the deploy direction 1, which in the present embodiment extends substantially perpendicular to the insert direction 2.

[0108] In the undeployed configuration 4 as for instance shown in FIGS. 3 and 4 the base 74 of the cartridge 70 at least partially extends beyond the outer circumference of the adjacently-located housing portion of the drug delivery device 10. In the undeployed configuration 4 as shown in FIG. 4, the fastener 14 is pivotable from the opened configuration 14c as shown in FIG. 4 into the closed configuration 14d as shown in FIG. 5. The pivotable fastener 14 comprises two portions, namely a base portion 30 by way of which the fastener 14 is pivotably attached to the housing 12 via a hinge 16. Attached to the base portion 30 the fastener 14 comprises a slider 32 forming a free end of the fastener 14 effectively providing a lid 15.

[0109] The slider 32 and the base portion are interconnected by means of a planar spring 34 as shown in FIG. 19. The spring 34 comprises a latch portion 35 to engage with two recesses 35a, 35b at an inside-facing portion of the slider 32. By way of the latch portion 35 engaging with either a distal recess 35b or with a proximal recess 35a, as indicated in FIGS. 20 and 21 the radial position of the slider 32 with regard to the base portion 30 and in regard to the hinge 16 and the pivot axis 18 can be modified. By means of the spring 34 and its latch portion 35 the slider 32 can be transferred from an extended configuration as shown in FIG. 21 into a retracted position 32b as shown in FIG. 20.

[0110] By way of the mutual interaction of the latch portion 35 with one of the recesses 35a, 35b, the slider 32 can be interlocked either in the extended position 32a or in the retracted position 32b. In addition the spring 34 also comprises two wings 36 extending at an angle from the plane surface of the spring 34 and extending into the receptacle 20 when the fastener 14 is in its closed configuration 14d. The wings 36 provide a particular pressure onto the cartridge 70 to keep the cartridge well seated and fixed in the receptacle 20. The slider 32 forms a kind of a U-shaped receptacle for the cartridge 70, in particular for the cartridge's base 74. When in closed configuration 14d, an inside-facing sidewall portion 32 of the retracted slider 32 may directly abut with an outside-facing sidewall portion of the cartridge 70, in particular of its base 74. By closing the fastener, hence by transferring and pivoting the fastener 14 in the closed configuration 14d, in which the slider is in its extended position 32a, the fastener 14 is also in a release configuration 14a as shown in FIG. 5.

[0111] Now, by displacing the slider 32 into the retracted position 32b as shown in FIG. 1 the cartridge 70 is displaced relative to the injector 60 along the deploy direction 1 to establish a fluid communication between the cartridge fluid coupling 90 and the injector fluid coupling 68. Simultaneously and in the same way the slider 32, hence the free end portion of the fastener 14 directly engages with the housing 12 of the drug delivery device. As becomes apparent from FIG. 2, inside a sidewall portion of the slider's 32 free end there are located two horizontally extending latch members 26 that are adapted to engage with horizontally and correspondingly-shaped grooves 24 of a latch member 32 extending from the housing 12 of the drug delivery device.

[0112] The grooves 24 of the latch members 23 are open in a direction opposite the deploy direction 1. They are therefore suitable to receive the corresponding latch members 26 of the slider 32 when the slider 32 is displaced from the extended position 32a into the retracted position 32b along the deploy direction 1. The retracted position 32b of the fastener 14 effectively coincides with the locking configuration 14b, supposed that the slider 32 is displaced when the fastener 14 is in closed configuration 14d. Similarly, the extended position 32a of the slider 32 coincides with the release configuration 14a of the fastener 14 supposed that the fastener is in closed configuration 14d when the slider 32 is displaced relative to the base portion 30.

[0113] Once the medicament contained in the reservoir 80 has been withdrawn thus requiring a replacement of the cartridge 70 the slider 32 may be displaced in a direction opposite to the deploy direction 1, typically by means of the ripples 33 provided at the outer surface of the free end of the slider 32. As soon as the latch members 26, 24 of slider 32 and housing 12 disengage, the fastener 14 will be automatically lifted by a predefined portion due to the wings 36 of the spring 34 applying pressure to the upper surface of the cartridge 70. This is a clear indication to the user, that the drug delivery device 10 is in a maintenance mode. Now, by pivoting the fastener 14 from the closed configuration 14d into the opened configuration 14c, a rear panel 31 extending radially from the pivot axis 18 engages with a sidewall portion 71a of the housing 71 of the cartridge 70, thereby displacing the cartridge 70 along the linear guiding 72 relative to the injector 60 toward the undeployed configuration.

[0114] As a consequence, and when reaching e.g. a 90° opening configuration of the fastener 14, the injector 60 and the cartridge 70 are again in their undeployed configuration 4. Hence, the injector fluid coupling 68 is disconnected form the cartridge 70 and its reservoir 80 so that any eventual residual portions of the medicament left in the reservoir 80 may not leave the cartridge 70. Contamination of the environment through and by the medicament can therefore be reduced and prevented.

[0115] In addition, the rear panel 31 extending at least partially into the receptacle 20 is of particular benefit to provide an effective safeguard mechanism. When closing the fastener 14, hence when pivoting the fastener 14 from the opened configuration 14c into the closed configuration 14d it is required, that the rear panel 31 may freely enter a recessed portion between the cartridge 70 and the injector 60. In circumstances, wherein the disposable injector 60 and the disposable cartridge 70 should be arranged or inserted into the receptacle 20 already in a deployed configuration 6 closing of the fastener 14 is effectively prevented since the rear panel 31 would evidently collide with the cartridge 70, in particular with a housing 71 thereof that faces away from the base 74.

LIST OF REFERENCE NUMBERS

[0116] 1 deploy direction
2 insert direction
4 undeployed configuration
6 deployed configuration
10 drug delivery device
12 housing
14 fastener
14a release configuration
14b locking configuration
14c opened configuration
14d closed configuration
15 lid
16 hinge
18 pivot axis
20 receptacle
21 sidewall
22 recessed structure
23 latch member
24 groove
26 latch member
30 base portion
31 rear panel
32 slider
32a extended position
32b retracted position
33 ripples
34 spring
35 latch portion
35a recess
35b recess
36 wing
37 decoupler
38 sidewall
50 delivery assembly
59 guide section
60 injector
61 base
62 mating structure
63 track
64 flexible tube
65 injection needle
66 piston
67 conduct
67a protector
68 injector fluid coupling
68a cannula
69 stop member
69a stop face
70 cartridge
71 housing
71a sidewall portion
72 linear guiding
73 recess
73a stop face
74 base
75 front face
76 socket

77 O-ring

[0117] 78 groove
79 groove
80 reservoir
81 flexible bag
82 pierceable seal
84 insert
85 through opening
86 fluid channel
88 closure
90 cartridge fluid coupling
100 feeder member
102 battery
104 injection drive
106 delivery drive