Sunscreen Compositions

Abstract

A sunscreen composition comprising one or more sunscreen actives, and at least two film formers is provided. The at least two film formers include an acrylates copolymer and a xanthan gum. The ratio of the acrylates copolymer to the xanthan gum is in a range of about 15:1 to about 1:1. The sunscreen composition provides water-resistant properties and very water-resistant properties after water immersion. The sunscreen composition can be present as a spray, cream, serum, lotion or continuous lotion spray.

Claims

1. A sunscreen composition, comprising: one or more sunscreen actives; and at least two film formers comprising an acrylates copolymer and a xanthan gum in a ratio from about 15:1 to about 1:1, wherein the sunscreen composition provides very water-resistant properties upon application on a substrate and subsequent to water immersion of the substrate.

2. The sunscreen composition of claim 1, wherein the sunscreen composition is free of oxybenzone and octocrylene.

3. The sunscreen composition of claim 1, wherein the xanthan gum comprises dehydroxanthan gum.

4. The sunscreen composition of claim 1, wherein the sunscreen composition further comprises a polyvinylpyrrolidone (PVP) polymer, wherein the polyvinylpyrrolidone (PVP) polymer is VP/eicosene copolymer or tricontanyl PVP.

5. The sunscreen composition of claim 4, wherein the tricontanyl PVP is present in an amount from about 0.075% to about 2.0% (w/w) by the total weight of the sunscreen composition.

6. The sunscreen composition of claim 4, wherein the sunscreen composition further comprises a rosinate resin, wherein the rosinate resin is methyl dihydroabietate.

7. The sunscreen composition of claim 6, wherein the polyvinylpyrrolidone (PVP) polymer and the rosinate resin is present in a ratio of about 15:1 to about 1:15.

8. The sunscreen composition of claim 1, wherein the one or more sunscreen actives comprise at least one organic sunscreen active.

9. The sunscreen composition of claim 8, wherein the at least one organic sunscreen active is selected from the group consisting of avobenzone, homosalate, salicylate derivatives, and combinations thereof

10. The sunscreen composition of claim 1, wherein one or more sunscreen actives are present in an amount of about 3% to about 30% (w/w) by the total weight of the sunscreen composition.

11. The sunscreen composition of claim 1, wherein an SPF rating from about 75% to about 100% is retained for at least eighty minutes upon application of the sunscreen composition and after immersion in water.

12. A method of protecting skin from ultraviolet radiation, comprising: applying a sunscreen composition to the skin, the sunscreen composition comprising: one or more sunscreen actives; and at least two film formers comprising an acrylates copolymer and a xanthan gum in a ratio of about 15:1 to about 1:1.

13. The method of claim 12, wherein the sunscreen composition further comprises a film former selected from the group consisting of a polyvinylpyrrolidone (PVP) polymer, a rosinate resin, and combinations thereof

14. The method of claim 13, wherein the ratio of the polyvinylpyrrolidone (PVP) polymer to the rosinate resin is from about 15:1 to about 1:15.

15. The method of claim 13, wherein the polyvinylpyrrolidone (PVP) polymer is VP/eicosene copolymer or tricontanyl PVP.

16. The method of claim 15, wherein the tricontanyl PVP is present in the sunscreen composition in an amount of about 0.075% to about 2.0% (w/w) by the total weight of the sunscreen composition.

17. The method of claim 12, wherein the sunscreen composition is free of oxybenzone and octocrylene.

18. The sunscreen composition of claim 1, wherein the sunscreen composition is a spray, lotion, light cream or continuous lotion spray.

19. The method of claim 12, wherein the sunscreen composition is a spray, lotion, light cream or continuous lotion spray.

20. The method of claim 12, wherein an SPF rating from about 75% to about 100% is retained for at least eighty minutes upon application of the sunscreen composition on the skin and after immersion in water.

Description

EXAMPLES

[0035] The following compositions provide examples of several embodiments of continuous spray oil-in-water emulsions described herein that provide very water-resistant results.

[0036] All compositions below are made according to the following procedure:

[0037] 1. Phase A and Phase C are separately heated to 75° C.

[0038] 2. Phase B is premixed and added to Phase A.

[0039] 3. Phase D is added to Phase C and then combined Phases C and D are then added to combined Phases A and B, and emulsified under homogenization (hereinafter, referred to as Main Phase).

[0040] 4. Begin cooling the Main Phase to 30° C.

[0041] 5. As the Main Phase cools, E-I are added to the Main Phase one at a time at suitable temperatures during the cool-down. Suitable temperatures are temperatures known to one skilled in the art, at which the integrity of the ingredients would be maintained.

[0042] The process can be modified to adjust the homogenizer speed having high shear rate to reduce the particle size of the emulsion, resulting in different forms of the composition including, milky lotion, watery lotion, lotion, serum, or light cream.

TABLE-US-00001 TABLE 1 Exemplary Sunscreen Compositions FOR- FOR- FOR- MULA MULA MULA 1 2 3 CTFA NAME (wt. %) (wt. %) (wt. %) Phase A Water 49.43 49.925 50.50 Trehalose 1.0 1.0 1.0 Sodium Dehydroacetate 0.1 0.1 0.1 Tetrasodium EDTA/Disodium EDTA 0.1 0.1 0.1 Caffeine 0.2 0.2 0.2 Aciylates Copolymer 0.375 0.375 0.18 Niacinamide 1.0 1.0 1.0 Glycerin 1.0 1.0 1.0 Phase B Butylene Glycol 2.0 2.0 2.0 Dehydroxanthan Gum 0.075 0.075 0.2 Phase C Butyloctyl Salicylate 4.0 4.0 4.0 Avobenzone 3.0 3.0 3.0 Neopentyl Glycol Diheptanoate 2.0 2.0 2.0 VP/Eicosene Copolymer 0.5 0.5 Tricontanyl PVP 0.5 BHT 0.09 0.09 0.09 Dipentaelythrityl Tri-Polyhydroxystearate 1.25 1.25 1.25 Homosalate 7.0 7.0 7.0 Ethylhexyl Salicylate 4.5 4.5 4.5 Tocopheryl Acetate 0.2 0.2 0.2 C12-15 Alkyl Benzoate/ Dipropylene Glycol Dibenzoate/ PPG-15 Stearyl Ether Benzoate 5.0 5.0 5.0 Polyester-8 3.0 3.0 3.0 Ethylhexyl Methoxycrylene 2.0 2.0 2.0 7-Dehydrocholesterol 0.01 0.01 0.01 Methyl Dihydroabietate 0.5 Phase D Potassium Cetyl Phosphate 2.0 2.0 2.0 Phase E Phenoxyethanol/Capry1y1 Glycol/ 1.3 1.3 1.3 Chlorphenesin Ethylhexylglycerin 0.3 0.3 0.3 Phase F Methyl Trimethicone 4.0 4.0 4.0 Lamyl PEG-9 Polydimethylsiloxyethyl 2.5 2.5 2.5 Dimethicone Cetyl PEG/PPG-10/1 Dimethicone 0.5 0.5 0.5 Phase G Algae Extract 0.05 0.05 0.05 Phase H Sorbitol 0.5 0.5 0.5 Phase I Water 0.5 0.5 0.5 Sodium Hyaluronate 0.02 0.02 0.02

Test Methods

In-Vivo SPF Testing Method

[0043] All in-vivo SPF measurements were made using the International SPF Test Method (May 2006) COLIPA test methods. SPF static and 80-minute very water-resistant assays were performed on the test subjects. The COLIPA test method is standardized as follows: the irradiation spectrum and the starting output of the sun simulator provided for the test are defined exactly. Additionally, the application amount and the nature of product application are precisely prescribed in the guidelines. The test method is independent of the skin type and the age of the test subjects and can be carried out in a statistical manner at n value greater than or equal to 10 subjects.

[0044] The test procedure includes determination of the minimum erythema dose (MED), i.e., the amount of UVB radiation which induces a just perceptible reddening (erythema) for each subject. Then skin on the back of each subject, which include test sites corresponding to untreated, unprotected skin, and test sites corresponding to areas having sunscreen test material, were exposed to radiation. Radiation sources include solar simulators, such as the Modified Solar Ultraviolet Simulator, Model 10S. The pre-immersion and post immersion SPF values were determined according to the COLIPA guidelines.

[0045] According to the COLIPA guidelines, a product will be considered very water resistant if the value for the 90% lower unilateral confidence limit is greater than or equal to 50% and the 95% confidence interval on the mean static SPF was within ±17% of the mean static SPF.

In-Vitro SPF Testing Method

[0046] In-vitro testing were performed by preparing the sunscreen test product on polymethylmethacrylate (PMMA) plates (e.g., the Helioplate HD6 available from Lapsphere) and measuring the SPF value using a spectrophotometer (e.g., the SPF-290 Analyzer from Optometrics Corporation). Product application per PMMA plate was approximately 1.3 mg/cm.sup.2. Pre-immersion SPF value was determined using the spectrophotometer. The sunscreen composition-treated plates were then transferred to a circulating temperature-controlled water bath at 37° C. for 80 minutes. The plates were allowed to dry, and the post-immersion SPF value was then determined.

TABLE-US-00002 TABLE 2 Water Resistant Test Results of Formulations in Table 1 (In-Vivo) POST-IMMER- WATER FOR- PRE-IMMER- SION RESISTANT MULA SION SPF SPF (W/R) 1 51 45 88.23% 2 52 45 86.53% 3 62 50 80.64%

TABLE-US-00003 TABLE 3 Water Resistant Test Results of Formulations in Table 1 (In-Vitro) AVERAGE AVERAGE WATER FOR- ESTIMATED UVA/UVB RESISTANT MULA SPF RATIO (W/R) 1 51 0.8 88.23% 2 52 0.81 86.53% 3 62 0.85   81%

[0047] As shown in Tables 2 and 3 above, the sunscreen compositions of Formulas 1, 2, and 3 all satisfy the COLIPA very water-resistant criteria of having a post-immersion SPF value greater than or equal to 50% of the pre-immersion SPF value. Furthermore, each of the in-vivo tests shown above meets the confidence level criteria of ±17%.

[0048] Compositions that are shown and tested below in Tables 4 and 5 are similar to Formula 1 shown in Table 1 above, with variations in the film formers used.

TABLE-US-00004 TABLE 4 Water Resistant Test Results for Compositions with Varying Ratios of Acrylates Copolymer to Xanthan Gum (In-Vitro) ACRYLATES COPOLYMER: AVERAGE AVERAGE WATER XANTHAN ESTIMATED UVA/UVB RESISTANT GUM SPF RATIO (W/R) 15:1 45 0.82 100% 7:1 50 0.79 100% 5:1 51 0.80  88% (formula 1 above, as control) 3:1 51 0.79  93% 2:1 55 0.81  79% 1:1.1 62 0.85  81% (formula 3 above)

TABLE-US-00005 TABLE 5 Water Resistant Test Results for Compositions with Varying Ratios of PVP Polymer to Rosinate Resin (In-Vitro) PVP POLYMER: AVERAGE AVERAGE WATER RONSINATE ESTIMATED UVA/UVB RESISTANT RESIN SPF RATIO (W/R) 15:1 56 0.83 74%  5:1 57 0.83 78%  1:l 51 0.84 88% (formula 1 above, as control)  1:5 51 0.80 84%  1:15 51 0.83 77%

[0049] As shown above in Table 4 above, compositions having a ratio of the acrylates copolymer to the dehydroyxanthan gum in the range of 15:1 to 1:1.1 provide varying levels of water resistance that meet the COLIPA very water resistant criteria. Furthermore, as shown in Table 5 above, compositions having a ratio of PVP polymer to the rosinate resin in the range of 15:1 to 1:15 also provide varying levels of water resistance that meet the COLIPA very water-resistant criteria. Compositions shown and tested below are similar to formula 3 in Table 1 above, with variations in the amount of tricontanyl PVP used.

TABLE-US-00006 TABLE 6 Water Resistant Test Results for Compositions with Varying Amount of Tricontanyl PVP (in-vitro) by the total weight of the composition AVERAGE AVERAGE WATER TRICONTANYL ESTIMATED UVA/UVB RESISTANT ARIATIONS SPF RATIO (W/R) 0.075% 51 0.79 97%  0.20% 47 0.81 99%  0.5% 52 0.81 87% (formula 2 above, as control)  1.0% 52 0.80 92%  2.0% 58 0.81 79%

[0050] As seen from Table 6 above, compositions having a range of about 0.075% to about 2.0% (w/w) of tricontanyl PVP by the total weight of the composition provide varying levels of water resistance that meet the COLIPA very water-resistant criteria.

[0051] Every document cited herein, including any cross referenced or related patent or application, is hereby incorporated herein by reference in its entirety unless expressly excluded or otherwise limited. The citation of any document is not an admission that it is prior art with respect to any invention disclosed or claimed herein or that it alone, or in any combination with any other reference or references, teaches, suggests or discloses any such invention. Further, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern.

[0052] While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.