OPENING AND CLOSING LID DEVICE AND AUTOMATIC ANALYZER INCLUDING SAME
20230258675 · 2023-08-17
Assignee
Inventors
Cpc classification
G01N35/00
PHYSICS
International classification
Abstract
An opening and closing lid device includes: an opening and closing lid that covers and freely opens or closes an opening portion that covers a first region including a pretreatment device; a support arm that connects the opening and closing lid and a support shaft in the first region, and is rotatably supported by the support shaft; and an opening holding mechanism that holds the support arm so as to hold the opening and closing lid in a fully opened position when a tip end of the opening and closing lid is at a position higher than a predetermined reference height, and releases holding of the support arm so that the opening and closing lid moves to the fully closed position due to own weight when the tip end of the opening and closing lid is at a position lower than the reference height.
Claims
1. An opening and closing lid device that is provided to cover a region cover and a first region provided on a work surface of a housing accommodating at least a part of functional portions of an analyzer, the opening and closing lid device comprising: an opening and closing lid that covers and freely opens or closes an opening portion provided on the region cover to access an inside of the first region from an outside; a support arm that connects, through the opening portion, a surface close to the first region of the opening and closing lid and a support shaft provided inside the first region and rotatably supports the opening and closing lid with respect to the support shaft; and an opening holding mechanism that holds the support arm so as to hold the opening and closing lid in a fully opened position when an end of the opening and closing lid at a side away from the support shaft is moved to a position higher than a predetermined reference height, and releases holding of the support arm so that the opening and closing lid moves to a fully closed position due to own weight when the end of the opening and closing lid is pressed down below the reference height, wherein the opening and closing lid is held such that the end at the side away from the support shaft is higher than the other end at a side close to the support shaft in the fully opened position and the other end is higher than the end in the fully closed position.
2. The opening and closing lid device according to claim 1, wherein the other end of the opening and closing lid is positioned above the support shaft in both the fully opened position and the fully closed position.
3. The opening and closing lid device according to claim 1, wherein the opening holding mechanism includes a receiving portion provided at the support arm, and a biasing portion that applies to the receiving portion a holding force for preventing the opening and closing lid from moving to the fully closed position due to own weight when the opening and closing lid is in the fully opened position.
4. The opening and closing lid device according to claim 3, wherein the opening holding mechanism releases biasing to the receiving portion applied by the biasing portion so that the opening and closing lid moves to the fully closed position due to own weight when the end of the opening and closing lid in the fully opened position is pressed down with a force equal to or larger than a predetermined force.
5. The opening and closing lid device according to claim 3, further comprising: a lower cover that is separated from and covers the support shaft and the opening holding mechanism from below.
6. The opening and closing lid device according to claim 1, further comprising: an airtight member that is provided at a boundary between the opening and closing lid in the fully closed position and the region cover, prevents inflow and outflow of air from occurring between the inside and the outside of the first region, and prevents light from entering the inside of the first region.
7. An automatic analyzer comprising: a sample container conveying mechanism on which a sample container accommodating a sample to be analyzed is placed and conveyed; a reagent container holding mechanism on which a reagent container accommodating a reagent for reacting with the sample is placed and held; a reaction mechanism on which a reaction vessel is placed, the sample and the reagent being reacted in the reaction vessel; a sample dispensing mechanism that dispenses the sample in the sample container into the reaction vessel; a reagent dispensing mechanism that dispenses the reagent in the reagent container into the reaction vessel; a pretreatment device that pre-treats a reaction solution of the sample and the reagent dispensed into the reaction vessel; a measurement device that measures the reaction solution subjected to a pretreatment by the pretreatment device; a region cover that is provided to cover a first region including the pretreatment device; and the opening and closing lid device according to claim 1.
Description
BRIEF DESCRIPTION OF DRAWINGS
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DESCRIPTION OF EMBODIMENTS
[0026] An embodiment of the invention will be described with reference to
[0027]
[0028] In
[0029] The housing 21 has, for example, a substantially rectangular parallelepiped shape in which the periphery of a highly rigid housing frame 55 formed by joining steel plates by welding, rivet fastening, or the like is covered with a front plate 56, left and right side plates 57, a rear plate 58, and an upper plate (that is, a work surface 22), and accommodates therein the sample conveying mechanism 5, the cleaning mechanism 17, the reagent cold storage 24, and constituent members of the analyzer such as substrates and flow paths (not shown). The front plate 56, the left and right side plates 57, and the rear plate 58 are detachable at the time of maintenance work.
[0030] The safety cover 4 is pivotally supported to be rotatable (openable and closable) around a cover support shaft 26 provided along a left-right direction on an upper portion of a rear surface of the housing 21. In
[0031] The sample conveying mechanism 5 includes, for example, a belt conveyor and a rack handler, and moves a sample 5a in the automatic analyzer 1 and conveys the sample 5a to a movable range of the sample dispensing mechanism 6.
[0032] The tip rack 7 is attachable to and detachable from the automatic analyzer 1, and is provided on an upper surface of the automatic analyzer 1 by the operator in a state in which a plurality of unused sample dispensing tips 10 and a plurality of unused reaction vessels 14 are placed.
[0033] The conveying mechanism 8 is movable in a planar direction (front-rear and left-right directions) and a Z-axis direction (an up-down direction), and is movable above the tip rack 7, a part of the incubator 9, the sample dispensing tip buffer 11, and the disposal hole 12. As the conveying mechanism 8, for example, a three-axis robot can be used. The conveying mechanism 8 grips the reaction vessels 14 one by one from the tip rack 7 and moves the reaction vessels 14 to the incubator 9. The conveying mechanism 8 grips the sample dispensing tips 10 one by one from the tip rack 7 and moves the sample dispensing tips 10 to the sample dispensing tip buffer 11.
[0034] The sample dispensing tip buffer 11 is a buffer on which the unused sample dispensing tips 10 conveyed from the tip rack 7 by the conveying mechanism 8 are temporarily placed. The sample dispensing tip buffer 11 is implemented such that the plurality of sample dispensing tips 10 can be placed thereon.
[0035] The incubator 9 has a substantially disc shape and is rotatable. The incubator 9 can hold the plurality of reaction vessels 14 along a circumferential direction, and each reaction vessel 14 can be moved to a predetermined position by the rotation of the incubator 9.
[0036] The sample dispensing mechanism 6 moves to a position above the sample dispensing tip buffer 11 to mount any one of the sample dispensing tips 10, and moves to a position above the sample 5a to aspirate the sample 5a into the sample dispensing tip 10. Thereafter, the sample dispensing mechanism 6 moves to a position above the reaction vessel 14 held on the incubator 9, and discharges the sample 5a from the inside of the sample dispensing tip 10 into the reaction vessel 14. Thereafter, the sample dispensing mechanism 6 moves to a position above the disposal hole 12, separates the sample dispensing tip 10, and drops the sample dispensing tip 10 into the disposal hole 12.
[0037] The reagent cold storage 24 has a substantially cylindrical shape and accommodates the reagent disk 2 therein. An upper surface of the reagent cold storage 24 is provided with a reagent container loading port 20 for attaching and detaching reagent containers 3 to and from the reagent disk 2. The reagent container loading port 20 is provided with an opening and closing reagent container loading port lid (not shown). The reagent cold storage 24 has a heat insulating function for controlling the temperature of a reagent accommodated in the reagent container 3 inside the reagent cold storage 24 to be constant.
[0038] The reagent disk 2 is rotatable around a central axis extending in an up-down axis direction, and has a plurality of slots for holding the reagent container 3 along a circumferential direction. The slot holds the reagent container 3 such that a longitudinal direction of the reagent container 3 is a radial direction of the reagent disk 2. Therefore, a plurality of reagent containers 3 are radially held on the reagent disk 2. By rotating the reagent disk 2, the reagent container 3 is moved to a predetermined position. For example, by rotating the reagent disk 2, the reagent container 3 accommodating a target reagent can be moved to a reagent dispensing position 15a.
[0039] The reagent dispensing probe 15 is movable in the front-rear and left-right directions (a horizontal direction) and the up-down direction by, for example, an actuator. The reagent dispensing probe 15 aspirates, by a reagent dispensing pipette (not shown), a predetermined amount of reagent from the reagent container 3 positioned at the reagent dispensing position 15a, and dispenses the reagent into the reaction vessel 14 held on the incubator 9.
[0040] The reaction vessel 14 into which the predetermined reagent and the sample 5a are dispensed is managed at a predetermined temperature by the incubator 9, and is stirred by the stirring mechanism 9a as necessary to promote a reaction for a predetermined time.
[0041] A reaction solution subjected to the reaction promotion by the incubator 9 is sent to the pretreatment device 13 by a transfer device (not shown) together with the reaction vessel 14, and a series of operations such as stirring of the reaction solution, supply of the reaction solution to the detection device 19, and disposal of the reaction solution and the reaction vessel 14 for which a measurement is completed are performed. Depending on a type of measurement, one reaction vessel 14 may be used for a plurality of measurements. In this case, after the reaction solution in the reaction vessel 14 for which analyses are completed is disposed, the reaction vessel 14 is washed.
[0042] Examples of physical characteristics of the reaction solution to be detected by the detection device 19 include, but are not limited to, a light emission amount, a scattered light amount, a transmitted light amount, a current value, and a voltage value. The detection device 19 is not limited to measuring the reaction solution supplied from the reaction vessel 14, and may perform the measurement while the reaction solution is held in the reaction vessel 14.
[0043] A host computer 200 is connected to the automatic analyzer 1, and a series of operations of the above configuration of the automatic analyzer 1 are controlled by the host computer 200.
[0044] The automatic analyzer 1 can efficiently analyze a plurality of analysis items for a plurality of samples by combining or repeating the operations described above under the control executed by the host computer 200.
[0045] Here, an opening and closing lid device provided to cover a region cover 23 (an outer cover) and a region (a first region) constituting the pretreatment device 13 provided on the work surface 22 on the housing 21, and the safety cover 4 that covers a work region (a second region) on the work surface 22 will be described in more detail.
[0046] A front side of the safety cover 4 is provided with a handhold portion 27 which is a concave portion into which fingers are inserted when opening the safety cover 4 from a closed position. The safety cover 4 is pivotally supported around the cover support shaft 26 provided along the left-right direction on the upper portion of the rear surface of the housing 21, and is rotatable (openable and closable) between a fully opened position and a closed position. When the safety cover 4 is opened, brought into contact with a stopper (not shown), and supported by a support mechanism (not shown) so as not to be closed due to own weight, the safety cover 4 is held in the fully opened position, and thus the operator can insert an arm or an upper body from a gap between the work surface 22 and the front side of the safety cover 4 to perform work on the work surface 22 which includes internal cleaning and replacement of consumables of the pretreatment device 13. During the work for the pretreatment device 13, the operator opens an opening and closing lid 16 (described later) provided in an opening portion of the region cover 23 to access the inside.
[0047]
[0048] The pretreatment device 13 is implemented in an internal region (the first region) of the box-shaped region cover 23 placed on the work surface 22 (that is, formed in a convex shape upward from the work surface). The pretreatment device 13 performs, as a series of analysis treatments on the sample, pretreatments for accurately measuring physical characteristics in the detection device 19 positioned in a subsequent stage, and includes therein a specimen container conveying mechanism, a specimen container stirring mechanism, a disposal unit that disposes of a specimen or a reaction vessel for which a measurement is completed, and the like.
[0049] The pretreatment device 13 includes a temperature adjustment device (not shown) such as a heater or a cooling element, and can maintain the inside of the region cover 23 at a predetermined temperature. The region cover 23 constituting an outer surface of the pretreatment device 13 is provided with the opening portion from a part of an upper surface to a front surface of the region cover 23, and the opening portion is provided with the opening and closing lid 16 that can be opened upward. By opening the opening and closing lid 16 (setting the opening and closing lid 16 to a fully opened position), the operator can access the inside of the pretreatment device 13, and can perform internal cleaning, component replacement, and the like of the pretreatment device 13, periodically or as necessary.
[0050] As shown in
[0051] A shape of an upper surface of the opening and closing lid 16 is, for example, a flat shape along a horizontal plane in a portion covering an upper surface of the pretreatment device 13 on a left side (a side far from the support shaft 37), a stepped shape rising upward toward a right side (a support shaft 37 side), and a shape connected to a hinge portion upper surface 33 positioned at an uppermost position via an inclined surface 32 inclined upward to the right along the hinge portion 25. An opening and closing lid rear end portion 34, which is a right end of the opening and closing lid 16, is provided at a position close to the hinge portion upper surface 33 in the inclined surface 32.
[0052] The opening and closing lid 16 is fixed to a mounting portion 36 provided at one end of the arm portion 35 from the inside of the pretreatment device 13. The other end of the arm portion 35 forms the support shaft 37, and is rotatably and pivotally supported by a support shaft bearing 38 provided in the vicinity of an upper right end of the hinge portion 25 placed on an upper portion of the pretreatment device 13. That is, the arm portion 35 and the opening and closing lid 16 integrally rotate around the support shaft 37 (the support shaft bearing 38).
[0053] Assuming that an end portion (a left end portion) of the opening and closing lid 16 farthest from the support shaft 37 is a tip end portion (an opening and closing lid tip end portion 40) of the opening and closing lid 16, when the opening and closing lid 16 is in the fully closed position (fully closed), the support shaft 37 in the vicinity of the right end of the opening and closing lid 16 is higher than the opening and closing lid tip end portion 40 at the left end. That is, a straight line connecting the support shaft 37 and the opening and closing lid tip end portion 40 of the opening and closing lid 16 is a straight line oriented downward to the left, and an angle α0 formed by the straight line and a horizontal plane including the support shaft 37 is a depression angle when the opening and closing lid tip end portion 40 is viewed from the support shaft 37 (see
[0054] As shown in
[0055] As shown in
[0056] As shown in
[0057] By performing a series of treatments in the pretreatment device 13 in a state in which the temperature inside the pretreatment device 13 is maintained at a predetermined temperature and the entry of external light is prevented, the measurement accuracy of physical characteristics in the detection device 19 is improved. Therefore, after the inside of the pretreatment device 13 is cleaned, it is required to reliably close the opening and closing lid 16 and then close the safety cover 4. More preferably, even if the operator forgets to close the opening and closing lid 16 and leaves the opening and closing lid 16 opened, the opening and closing lid 16 is closed in conjunction with closing of the safety cover 4.
[0058]
[0059] As shown in
[0060] From the fully closed state to the fully opened state of the opening and closing lid 16, the second arm portion 35b is provided within a range opened by the opening and closing lid 16 in the region cover 23, and is implemented as a so-called take-out hinge. When the opening and closing lid 16 is closed (when the opening and closing lid 16 is moved to the fully closed position), the second arm portion 35b enters the inside of the opening portion together with the mounting portion 36, and thus the opening and closing lid boundary portion 28 between the opening and closing lid 16 and the region cover 23 can form a closed curve continuous over the entire periphery of the opening and closing lid. Therefore, due to the airtight member 29 provided along the boundary portion, it is possible to prevent entry of external light while maintaining airtightness when the opening and closing lid 16 is closed.
[0061]
[0062] As shown in
[0063] As shown in
[0064] In the present embodiment, the lower cover 45, the biasing member 46, the arm portion 35, and the opening and closing lid 16 may be made of resin, and for example, if the opening and closing lid 16 is made of acrylonitrile butadiene (ABS) resin, and the lower cover 45, the biasing member 46, and the arm portion 35 are made of polyacetal (POM) resin, there is an effect of reducing the number of components and realizing simplification and cost reduction.
[0065] When the opening and closing lid 16 is moved from the fully closed position shown in
[0066] As shown in
[0067] At this time, a straight line connecting the support shaft 37 and the opening and closing lid tip end portion 40 of the opening and closing lid 16 is a straight line oriented upward to the left, and an angle α1 formed by the straight line and the horizontal plane including the support shaft 37 is an elevation angle when the opening and closing lid tip end portion 40 is viewed from the support shaft 37. The height from the floor surface to the opening and closing lid tip end portion 40 is H1.
[0068] That is, when the height of the opening and closing lid tip end portion 40 is H3 or less, a positional relation is established in which the support moment implemented by the lock surface 49 of the biasing member 46 does not act on the corner portion 42 of the arm portion 35, and thus the opening and closing lid 16 is not locked and is closed due to the own weight. When the height of the opening and closing lid tip end portion 40 is higher than H4, the corner portion 42 is held by the lock surface 49, and the opening and closing lid 16 is locked in the fully opened state (in the fully opened position).
[0069] In the fully opened state, for example, when the opening and closing lid tip end portion 40 of the opening and closing lid 16 is lowered by being pressed from above until the height becomes H3 or less, a fully opening lock by the lock mechanism 30 is released, and the opening and closing lid 16 is closed due to the own weight and rotates to the fully closed position. Hereinafter, the height H3 is referred to as an opening lock release height.
[0070] When a force F2 is applied downward to the opening and closing lid tip end portion 40 in the fully opened state, a closing moment applied to the opening and closing lid 16 is a sum of an own weight moment and a product of the force F2 and a horizontal distance R3 from the support shaft 37 to the opening and closing lid tip end portion 40, and is expressed as (mg×R1)+(F2×R3).
[0071] Although the corner portion 42 receives the reaction force F1 from the lock surface 49 and maintains the opening and closing lid 16 in the fully opened state, the reaction force F1 generated by the biasing member 46 is limited. When an allowable maximum value F1max or more is applied, the biasing member 46 is deflected in a direction away from the support shaft 37, and the corner portion 42 is disengaged from the lock surface 49, whereby the opening and closing lid 16 is closed from the fully opened state due to the own weight.
[0072] That is, when the downward closing force F2 is applied to the opening and closing lid tip end portion 40 in the fully opened state and a relation of [(mg×R1)+(F2×R3)]>(F1max×R2) is established, the fully opening lock is released and the opening and closing lid 16 is closed due to the own weight and return to the fully closed position (see
[0073] That is, rigidity of the biasing member 46 and dimensions of the claw portion 48 and the lock surface 49 are determined such that the fully opened state can be maintained by supporting the closing moment due to the own weight when the opening and closing lid 16 is fully opened, and the lock is released and the opening and closing lid 16 is closed due to the own weight when a downward closing force is applied to the opening and closing lid tip end portion 40.
[0074] As shown in
[0075] As shown in
[0076] Actions and effects of the present embodiment having the above configuration will be described with reference to a comparative example.
[0077]
[0078] As shown in
[0079] As shown in
[0080] Meanwhile, as shown in
[0081] However, as described above, when the opening angle α2 is increased and the horizontal distance R3′ from the opening and closing lid tip end portion 40 to the support shaft 37A is decreased, a closing moment when the closing force F2 from above is applied to the opening and closing lid tip end portion 40 is decreased, and a height R4′ from the opening and closing lid tip end portion 40 to the support shaft is increased, and a frictional moment R4′×μ×F2 due to a frictional force is increased. Therefore, the frictional moment becomes larger than the closing moment, and the opening and closing lid 16A becomes a so-called strut rod, which is likely to be a condition under which the opening and closing lid 16A is not closed even when pressed from above, and closing reliability of the opening and closing lid 16A is significantly reduced.
[0082] Regarding an opening region 51A (indicated by hatching in
[0083] On the other hand, in the present embodiment, the hinge portion 25 is placed on the upper portion of the pretreatment device 13, and the position of the support shaft 37 is provided above the pretreatment device 13, so that the opening and closing lid 16 is directed downward to the left in the fully closed position and is directed upward to the left in the fully opened position. Therefore, the opening region 51 sufficient for the operator can be obtained in the fully opened position, and the opening and closing lid 16 can be reliably closed (that is, rotated to the fully closed position) when the opening and closing lid tip end portion 40 is pressed from above in the fully opened position, and thus the opening and closing lid 16 having high reliability and easy to use can be obtained.
<Supplementary Notes>
[0084] The invention is not limited to the above embodiment, and includes various modifications and combinations without departing from the gist of the invention. The invention is not limited to a configuration including all the configurations described in the above embodiment, and includes a configuration in which a part of the configuration is deleted.
[0085] For example, in the present embodiment, since the opening and closing lid tip end portion 40 is provided on the left side of the support shaft 37, the opening and closing lid 16 is directed downward to the left in the fully closed position and upward to the left in the fully opened position, whereas for example, in an embodiment in which the opening and closing lid tip end portion 40 is provided on the right side of the support shaft 37, the opening and closing lid 16 is directed downward to the right in the fully closed position and upward to the right in the fully opened position.
REFERENCE SIGNS LIST
[0086] 1: automatic analyzer [0087] 2: reagent disk [0088] 3: reagent container [0089] 4: safety cover [0090] 5: sample conveying mechanism [0091] 5a: sample [0092] 6: sample dispensing mechanism [0093] 7: tip rack [0094] 8: conveying mechanism [0095] 9: incubator [0096] 9a: stirring mechanism [0097] 10: sample dispensing tip [0098] 11: sample dispensing tip buffer [0099] 12: disposal hole [0100] 13, 13A: pretreatment device [0101] 14: reaction vessel [0102] 15: reagent dispensing probe [0103] 15a: reagent dispensing position [0104] 16, 16A: opening and closing lid [0105] 17: cleaning mechanism [0106] 19: detection device [0107] 20: reagent container loading port [0108] 21: housing [0109] 22: work surface [0110] 23: region cover [0111] 24: reagent cold storage [0112] 25: hinge portion [0113] 26: cover support shaft [0114] 27: handhold portion [0115] 28: opening and closing lid boundary portion [0116] 29: airtight member [0117] 30: lock mechanism [0118] 31: pretreatment unit upper surface [0119] 32: inclined surface [0120] 33: hinge portion upper surface [0121] 34: opening and closing lid rear end portion [0122] 35: arm portion [0123] 35a: first arm portion [0124] 35b: second arm portion [0125] 36: mounting portion [0126] 37, 37A: support shaft [0127] 39: knob portion [0128] 40: opening and closing lid tip end portion [0129] 42: corner portion [0130] 44a, 44b: rib [0131] 45: lower cover [0132] 46: biasing member [0133] 47: lower cover bottom surface [0134] 48: claw portion [0135] 49: lock surface [0136] 50: slanting surface [0137] 51, 51A: opening region [0138] 55: housing frame [0139] 56: front plate [0140] 57: left and right side plates [0141] 58: rear plate [0142] 200: host computer