COSMETIC COMPOSITION FOR SKIN BARRIER STRENGTHENING OR MOISTURIZING COMPRISING FERMENTED RICE EXTRACTS, PINEAPPLE EXTRACTS, AND GLYCERYL GLUCOSIDE MIXTURE

Abstract

The present invention relates to a cosmetic composition and/or a skin external application agent for skin barrier strengthening or moisturizing comprising fermented rice extracts, pineapple extracts and glyceryl glucoside mixture.

Claims

1. A cosmetic composition for improving skin barrier strengthening or moisturizing, comprising a composition comprising fermented rice extracts, pineapple extracts and glyceryl glucoside mixture.

2. The cosmetic composition as claimed in claim 1, wherein the weight ratio of the fermented rice extracts, pineapple extracts and glyceryl glucoside mixture is 1:1:1.

3. The cosmetic composition as claimed in claim 1, wherein the fermented rice extracts contain antioxidants (Thioredoxin) having a concentration of 400 ug/L or more.

4. The cosmetic composition as claimed in claim 1, wherein the pineapple extracts contain a ceramide content of 40 g/L or more.

5. The cosmetic composition as claimed in claim 1, wherein the glyceryl glucoside mixture contains a content of a compound of glycerin and glucose of 60% or more having a purity of 90% or more after chemical bonding between glycerin and glucose.

6. The cosmetic composition as claimed in claim 1, wherein the cosmetic composition is applied to at least one type selected from the group consisting of a patch, mask pack, mask sheet, cream, tonic, ointment, suspension, turbid fluid, paste, lotion, gel, oil, pack, spray, aerosol, mist, foundation, powder, and oil paper.

7. The cosmetic composition as claimed in claim 6, wherein the cosmetic composition is applied or deposited on at least one surface of patch, mask pack or mask sheet.

8. A cosmetic method for controlling condition of a skin of a mammal by improving skin barrier strengthening or moisturizing of stratum corneum except for treatment, comprising: (a) directly applying the cosmetic composition according to claim 1 to the skin of the mammal, or (b) contacting or attaching the applied or deposited patch, mask pack, or mask sheet to the skin of the mammal, or sequentially proceeding the steps (a) and (b).

9. The cosmetic method as claimed in claim 8, further comprising: (c) removing the patch, mask pack or mask sheet from the skin of the mammal after step (b), and applying the composition for improving skin barrier strengthening or moisturizing to the skin of the mammal.

10. The cosmetic method as claimed in claim 8, wherein the cosmetic composition is used in lotion or cream.

Description

DETAILED DESCRIPTION

[0012] Hereinafter, according to a specific embodiment of the present invention, a cosmetic composition and/or skin external application agent for improving skin barrier strengthening or moisturizing will be described in detail. However, it is apparent to those skilled in the art that this embodiment is provided as an example of the invention, whereby the scope of the invention is not limited, and various modifications to the embodiments are possible within the scope of the invention.

[0013] As used herein, the term “skin barrier strengthening” means protecting, strengthening, or improving skin barrier function of the skin stratum corneum, and does not mean regeneration or function improvement of dermis or subcutaneous fat tissue. For example, the “skin barrier strengthening” prevents moisture loss in the stratum corneum, improves indicators of moisture reduction in the stratum corneum, such as transepidermal water loss (TEWL), and improves skin barrier indicators such as increasing skin moisture content (skin hydration). Accordingly, it is meant to bring about the protection, strengthening and/or improvement of the skin barrier function of the skin stratum corneum in the true sense.

[0014] As used herein, the term “skin moisturizing” means maintaining the homeostasis of a living body by appropriately controlling the moisture loss (moisture evaporation) of the skin.

[0015] In a first embodiment,

[0016] the present invention is intended to provide a cosmetic composition and/or skin external application agent for improving skin barrier strengthening or moisturizing, comprising a composition comprising fermented rice extracts, pineapple extracts and glyceryl glucoside mixture.

[0017] According to the cosmetic composition and/or skin external application agent of the present invention, the weight ratio of the fermented rice extracts, pineapple extracts and glyceryl glucoside mixture may be 1:1:1.

[0018] According to the cosmetic composition and/or skin external application agent of the present invention, the fermented rice extracts may contain antioxidants (Thioredoxin) having a concentration of 400 ug/L or more. The rice may be selected from the group consisting of brown rice and white rice. The fermentation may be carried out using natural yeast.

[0019] According to the cosmetic composition and/or skin external application agent of the present invention, the pineapple extracts may contain a ceramide content of 40 g/L or more.

[0020] According to the cosmetic composition and/or skin external application agent of the present invention, the glyceryl glucoside mixture may contain a content of a compound of glycerin and glucose of 60% or more having a purity of 90% or more after chemical bonding between glycerin and glucose.

[0021] According to the cosmetic composition and/or skin external application agent of the present invention, the cosmetic composition and/or skin external application agent may be appropriately blended with antioxidants, oily ingredients, ultraviolet absorbers, emulsifiers, surfactants, thickeners, alcohols, powder components, coloring materials, aqueous components, water and various skin nutrients, as components commonly used in cosmetics or skin external application agents as needed, within the range not impairing the effects of the present invention.

[0022] According to the present invention, the cosmetic composition and/or skin external application agent may be applied to at least one type selected from the group consisting of patch, mask pack, mask sheet, cream, tonic, ointment, suspension, turbid fluid, paste, lotion, gel, oil, pack, spray, aerosol, mist, foundation, powder, and oil paper. For example, the cosmetic composition and/or skin external application agent may be formulated with by a patch, mask pack, mask sheet, softening lotion, nourishing lotion, astringent lotion, nourishing cream, massage cream, eye cream, cleansing cream, essence, eye essence, cleansing lotion, cleansing foam, cleansing water, sunscreen, lipstick, soap, shampoo, surfactant-containing cleansing, bathing agent, body lotion, body cream, body oil, body essence, body cleanser, hair dye, hair tonic, etc., but is not limited thereto. The cosmetic composition and/or skin external application agent may be applied or deposited on at least one surface of the patch, mask pack, or mask sheet.

[0023] In a second embodiment,

[0024] the present invention is intended to provide a cosmetic method for controlling a condition of a skin of a mammal by improving skin barrier strengthening or moisturizing of the stratum corneum except for treatment, using a composition comprising fermented rice extracts, pineapple extracts and glyceryl glucoside mixture.

[0025] According to the cosmetic method for controlling a condition of a skin of a mammal of the present invention, the cosmetic method may include (a) directly applying the cosmetic composition for improving skin barrier strengthening or moisturizing to the skin of the mammal, or (b) contacting or attaching the applied or deposited patch, mask pack, or mask sheet with the cosmetic composition for improving skin barrier strengthening or moisturizing to the skin of the mammal, or sequentially proceeding the steps (a) and (b). In the step (a), the composition for improving skin barrier strengthening or moisturizing may be used in the lotion or cream.

[0026] According to the cosmetic method for controlling a condition of a skin of a mammal of the present invention, the cosmetic method may further comprise (c) removing the patch, mask pack or mask sheet from the skin of the mammal after step (b), and applying the composition for improving skin barrier strengthening or moisturizing to the skin of the mammal. In the step (c), the composition for improving skin barrier strengthening or moisturizing may be used in the lotion or cream.

[0027] Hereinafter, the present invention will be described in more detail through examples. However, these are only for describing the present invention in more detail, and the scope of the present invention is not limited thereto.

EXAMPLE

Example 1: Preparation Fermented Rice Extracts, Pineapple Extracts and Glyceryl Glucoside Mixture

[0028] The rice fermented extracts, eco-friendly pineapple extracts, and glyceryl glucoside compound were mixed in purified water containing 2% 1, 2-hexanediol, respectively, in a weight ratio according to Table 1 below. Here, the fermented rice extracts were induced to contain an antioxidant (Thioredoxin) concentration of 400 ug/L or more during the fermentation process of rice using natural yeast. The eco-friendly pineapple extracts were extracted so that the content of natural sugar ceramide could be 40 g/L or more by using an outer skin discarded after removing flesh. In the glyceryl glucoside compound, the content of glycerin & glucose compounds of a purity of 90% or more was found to be 60% or more after chemical bonding between the glycerin and the glucose. Each mixture was put into a water jacket reactor capable of maintaining a temperature, heated to 55 to 65° C., and stirred at 700 rpm for 4 hours. After the stirring was completed, the mixture was firstly filtered through a 100 um Cellulose Acetate filter, and secondly filtered through a 0.22 μm PVDF filter.

TABLE-US-00001 TABLE 1 Fermented rice Pineapple Glyceryl extracts extracts Glucoside Example 1 0 1 1 Example 2 1 0 1 Example 3 1 1 0 Example 4 1 1 1

Experimental Example

Experimental Example 1: Confirmation of Transepidermal Water Loss (TEWL) Alleviation Effect of the Composition According to the Present Invention

[0029] To induce an increase in TEWL, ethanol was applied to the inner arm of 10 men and women aged 26 to 44 years old, and then TEWL index of the corresponding site was measured using a skin condition-measuring device (GPSKIN) at five points. The purified water used as Examples 1 to 4 and control group was applied to the five points, and after 30 minutes, the TEWL indices were measured at the five points using the GPSKIN.

TABLE-US-00002 TABLE 2 ID Gender Age Sort TEWL  1 M 41 Purified water 13 Example 1 11 Example 2 12 Example 3 12 Example 4  9 F 44 Purified water 14 Example 1 13 Example 2 12 Example 3 14 Example 4  8 F 26 Purified water 10 Example 1  9 Example 2  9 Example 3  7 Example 4  6 F 27 Purified water 11 Example 1 10 Example 2 10 Example 3 11 Example 4  6 F 26 Purified water 14 Example 1 12 Example 2 12 Example 3 13 Example 4  9  6 F 28 Purified water 13 Example 1 11 Example 2 11 Example 3 12 Example 4  9  7 F 32 Purified water 24 Example 1 20 Example 2 19 Example 3 22 Example 4 15  8 M 30 Purified water 11 Example 1  9 Example 2 10 Example 3 10 Example 4  7  9 M 38 Purified water 12 Example 1 11 Example 2 11 Example 3 12 Example 4  9 10 F 45 Purified water 13 Example 1 10 Example 2 11 Example 3 11 Example 4  8

[0030] As a result, as may be seen from Table 2, Examples 1 to 4 exhibited reduced TEWL compared to the control group (purified water), and among them, an effect of the TEWL relaxation according to Example 4 was remarkably excellent.

Experimental Example 2: Confirmation of an Effect of Skin Moisture Index of the Composition According to the Present Invention

[0031] In order to know the change in the moisture index of 10 testers, the moisture index was measured before applying the five points on the inside of the arm. The purified water used as Examples 1 to 4 and the control group was applied to the five points, and after 30 minutes, the moisture index was measured at the five points using the GPSKIN.

TABLE-US-00003 TABLE 3 Moisture ID Gender Age Sort index  1 M 41 Purified water 52 Example 1 84 Example 2 85 Example 3 83 Example 4 96  2 F 44 Purified water 71 Example 1 88 Example 2 86 Example 3 85 Example 4 94  3 F 26 Purified water 54 Example 1 85 Example 2 83 Example 3 84 Example 4 91  4 F 27 Purified water 51 Example 1 82 Example 2 80 Example 3 81 Example 4 93  5 F 26 Purified water 53 Example 1 91 Example 2 89 Example 3 86 Example 4 96  6 F 28 Purified water 54 Example 1 90 Example 2 89 Example 3 89 Example 4 95  7 F 32 Purified water 63 Example 1 91 Example 2 90 Example 3 88 Example 4 97  8 M 30 Purified water 66 Example 1 95 Example 2 96 Example 3 94 Example 4 98  9 M 38 Purified water 51 Example 1 81 Example 2 82 Example 3 80 Example 4 90 10 F 45 Purified water 59 Example 1 92 Example 2 93 Example 3 91 Example 4 96

[0032] As a result, as can be seen from Table 3, Examples 1 to 4 showed increased moisture index compared to the control group (purified water), and particularly, the effect of increasing the level index according to Example 4 was remarkably excellent.

Experimental Example 3: Confirmation of an Effect of Skin Barrier Index of the Composition According to the Present Invention

[0033] In order to reduce the skin barrier index, the five points were set on the inner part of the arm of 10 testers, and 5 tapes were stripped on the part and then the skin barrier of the part where 5 tapes were stripped using the skin condition measuring device (GPSKIN) The index was measured. Examples 1 to 4 were applied to four of the five points where tape stripping was performed, and after 30 minutes, the skin barrier index was measured using the GPSKIN at the five points and compared with the unapplied points.

TABLE-US-00004 TABLE 4 Skin barrier ID Gender Age Sort index  1 M 41 Stripping point 76 Example 1 84 Example 2 82 Example 3 82 Example 4 86  2 F 44 Stripping point 71 Example 1 83 Example 2 82 Example 3 83 Example 4 89  3 F 26 Stripping point 87 Example 1 82 Example 2 88 Example 3 87 Example 4 92  4 F 27 Stripping point 76 Example 1 90 Example 2 88 Example 3 86 Example 4 92  5 F 26 Stripping point 71 Example 1 85 Example 2 81 Example 3 82 Example 4 89  6 F 28 Stripping point 72 Example 1 82 Example 2 80 Example 3 81 Example 4 84  7 F 32 Stripping point 51 Example 1 76 Example 2 78 Example 3 75 Example 4 85  8 M 30 Stripping point 76 Example 1 76 Example 2 77 Example 3 78 Example 4 89  9 M 38 Stripping point 74 Example 1 81 Example 2 80 Example 3 82 Example 4 86 10 F 45 Stripping point 72 Example 1 78 Example 2 79 Example 3 76 Example 4 82

[0034] As a result, as may be seen from Table 4, Examples 1 to 4 showed an increased skin barrier index compared to the control group (striping point), and particularly, the skin barrier index according to Example 4 was remarkably high.

Experimental Example 4: Confirmation of an Effect of Improving Skin Condition of a Cream Formulation Containing the Composition According to the Present Invention

[0035] In order to know the effect of improving skin condition of the cream formulation containing the composition according to the present invention, three points were designated on the inside of the arms of 10 testers. In addition, it was classified into a cream added with mixture (test group), and a cream without mixture (control group) and an untreated group, and the TEWL, skin moisture index, and skin barrier index were confirmed.

TABLE-US-00005 TABLE 5 Skin Skin barrier moisture ID Gender Age index index TEWL  1 M 41 Before Test 84  50  6 Control 76  84 11 (control group) Test (EQ) 86 100  7  2 F 44 Before Test 83  68  5 Control 71  87 14 (control group) Test (EQ) 89  99  8  3 F 26 Before Test 87  59  5 Control 88  88  6 (control group) Test (EQ) 88  99  5  4 F 27 Before Test 89  50  3 Control 76  85 11 (control group) Test (EQ) 92  99  5  5 F 26 Before Test 81  50  7 Control 71  94 14 (control group) Test (EQ) 85 100  9  6 F 28 Before Test 82  54  8 Control 72  92 13 (control group) Test (EQ) 84 100  7  7 F 32 Before Test 76  63  7 Control 51  93 24 (control group) Test (EQ) 85 100 11  8 M 30 Before Test 76  66  6 Control 76  98 11 (control group) Test (EQ) 89  99 11  9 M 38 Before Test 81  50  8 Control 74  75 12 (control group) Test (EQ) 86 100  9 10 F 45 Before Test 82  52  6 Control 66  78 12 (control group) Test (EQ) 90 100  7

[0036] As a result, it was confirmed that the cream of the preparation example containing fermented rice extracts, pineapple natural sugar ceramide extracts, and the glyceryl glucoside mixture (Example 4) according to the present invention has remarkably superior effects in TEWL relief, the increase of the skin moisture index, and the skin barrier index strengthening, compared to the control group.

[0037] As described above, the specific parts of the present invention have been described in detail. Accordingly, it will be apparent to those of ordinary skill in the art that these specific techniques are only preferred embodiments, and the scope of the present invention is not limited thereby. Therefore, it may be seen that the substantial scope of the present invention is defined by the appended claims and their equivalents.