EDIBLE COMPOSITION FOR PROMOTING HAIR GROWTH AND DELAYING HAIR GRAYING

Abstract

The present invention provides an edible composition for promoting hair growth and delaying hair graying. The composition comprises in parts by weight: 2 to 30 parts of nucleoprotein peptides, 1 to 25 parts of whole coffee fruit extract, 5 to 60 parts of yeast composite powder and 10 to 55 parts of collagen. The edible composition for promoting hair growth and delaying hair graying provided by the present invention can promote hair growth, with a significant change in fine hair after 1 week of consumption and a 2 to 3 times increase in fine hair after 8 weeks of consumption, a significant reduction in the percentage of grey hair after 2 weeks of consumption, and a 10% to 40% reduction in the percentage of grey hair after 8 weeks of consumption. It also has an effect in skin improvement.

Claims

1. An edible composition comprising in parts by weight: TABLE-US-00004 nucleoprotein peptides 2 to 30 parts; whole coffee fruit extract 1 to 25 parts; yeast composite powder 5 to 60 parts; collagen 10 to 55 parts.

2. The edible composition according to claim 1, wherein the content of the nucleoprotein peptides is from 2% to 30%, based on a total mass of the composition of 100%.

3. The edible composition according to claim 1, wherein the content of the whole coffee fruit extract is from 1% to 25%, based on a total mass of the composition of 100%.

4. The edible composition according to claim 1, wherein the content of the yeast composite powder is from 5% to 60%, based on a total mass of the composition of 100%.

5. The edible composition according to claim 1, wherein the content of collagen is from 10% to 55%, based on a total mass of the composition of 100%.

6. The edible composition according to claim 1, wherein the composition consists of nucleoprotein peptides, whole coffee fruit extract, yeast composite powder, and collagen.

7. The edible composition according to claim 1, wherein the nucleoprotein peptides are nucleoprotein peptide compositions with sodium deoxyribonucleic acid content of 86% or more.

8. The edible composition according to claim 1, wherein the whole coffee fruit extract comprises 30% or more of chlorogenic acid.

9. The edible composition according to claim 1, the whole coffee fruit extract comprises 20% to 50% total chlorogenic acids and 0.5% to 5% of proanthocyanidin.

10. The edible composition according to claim 9, wherein the total chlorogenic acids include neochlorogenic acid, and the neochlorogenic acid is present in the whole coffee fruit extract in a percentage of 1% to 20%.

11. Use of the edible composition according to claim 1 for promoting hair growth.

12. Use of the edible composition according to claim 1 for delaying hair graying.

13. Use of the edible composition according to claim 1 for skin improvement.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0023] FIG. 1 shows a comparison in the activation of tyrosine kinase by various components in the Examples.

[0024] FIG. 2 shows a comparison of the changes in hair counts before and after the consumption of the composition of the present invention in the Examples.

[0025] FIG. 3 shows a comparison of the changes in the percentage of grey hair and the percentage of fine hair after the consumption of the composition of the present invention in the Examples.

[0026] FIG. 4 shows a comparison of the changes in hair follicles before and after the consumption of the composition of the present invention in the Examples.

[0027] FIG. 5 shows a comparison of the conditions of grey hair before and after the consumption of the composition of the present invention in the Examples.

[0028] FIG. 6 shows a comparison of the changes in skin firmness before and after the consumption of the composition of the present invention in the Examples.

[0029] FIG. 7 shows a comparison of the changes in skin age after consumption of the composition of the present invention in the Examples.

[0030] FIG. 8 shows a comparison of the conditions of grey hair, the percentages of fine hair and the conditions of dark hair before and after the consumption of another composition of the present invention in the Examples.

[0031] FIG. 9 shows a comparison of the changes in skin firmness before and after the consumption of another composition of the present invention in the Examples.

DETAILED DESCRIPTION

[0032] In order to provide a better understanding of the technical features, objects and advantageous effects of the present invention, detailed description of the technical solutions of the present invention is provided herein below, which is not to be construed as limiting the implementable scope of the present invention.

EXAMPLE 1

[0033] This example provides a composition for promoting hair growth and delaying hair graying, wherein the composition comprises in parts by weight:

TABLE-US-00002 nucleoprotein peptides (DNA-Na content >86%) 5 parts; whole coffee fruit extract (chlorogenic acid content >30%) 3 parts; yeast composite powder (pantothenic acid >1.1%) 14 parts; collagen 20 parts; sorbitol 57.8 parts; magnesium stearate 0.2 parts.

[0034] The composition was prepared as follows: nucleoprotein peptides (purchased from Maruha Nichiro Corp.), whole coffee fruit extract (obtained by extracting coffee fruits in an aqueous ethanol solution, concentrating and drying), yeast composite powder, collagen, sorbitol and magnesium stearate were proportionally weighed and uniformly mixed, and then pressed into tablets to obtain the composition for promoting hair growth and delaying hair graying.

[0035] In this example, comparative experiments were carried out for the activation rate of tyrosinase by the raw material whole coffee fruit extract, with polygonum multiflorum extract, black sesame extract, yeast composite powder, and nucleoprotein peptides used in the comparative examples, respectively. The results of the experiments are shown in FIG. 1. As can be seen from FIG. 1, the activation rate of tyrosinase by the whole coffee fruit extract reaches 37.39%, and the activation rate of tyrosinase by the whole coffee fruit extract in combination with nucleoprotein peptides reaches 44.91%, which are higher than the other comparative examples.

EXAMPLE 2

[0036] This example provides a composition for promoting hair growth and delaying hair graying, wherein the composition comprised, in parts by weight:

TABLE-US-00003 nucleoprotein peptides (DNA-Na content >86%) 8 parts; whole coffee fruit extract (chlorogenic acid content >30%) 9 parts; yeast composite powder (>1.1% pantothenic acid) 22 parts; collagen 23 parts; maltodextrin 38 parts.

[0037] The composition was prepared as follows: nucleoprotein peptides (purchased from Maruha Nichiro Corp.), whole coffee fruit extract (obtained by extracting coffee fruits in an aqueous ethanol solution, concentrating and drying), yeast composite powder, collagen and maltodextrin were proportionally weighed and uniformly mixed, and formulated into capsules of the composition for promoting hair growth and delay hair graying.

Application Example 1

[0038] The composition of Example 1 was used in the treatment of hair loss and premature hair graying. The results of the experiment are shown in FIGS. 2 and 3. As can be seen from panel A in FIG. 3, the percentage of grey hair was significantly reduced after 2 weeks of consumption and decreased by 10% to 40% after 8 weeks of consumption. As can be seen from panel B in FIG. 3, the fine hair were significantly changed after 1 week of consumption and increased by 2 to 3 times after 8 weeks of consumption. With the period of consumption time extended, the percentage of grey hair was remarkably reduced, as shown in FIGS. 4 and 5. As such, the composition of the present invention can promote hair growth and delay hair graying at the same time. In addition, the skin firmness of the subjects was improved after 3 weeks of consumption (see FIG. 6), and the skin age also decreased after 5 weeks of consumption, as shown in FIG. 7.

Application Example 2

[0039] 1.6 g of the capsules of the composition prepared according to Example 2 was taken daily by subjects, and the condition of the hair follicles at fixed locations on the subjects' head was monitored weekly with a hair follicle instrument, photographed and the number of hairs were counted; at the same time, the condition of the skin at fixed locations on the subjects' face was also monitored with a skin detector. The results of the experiments are shown in FIGS. 8 and 9. As can be seen in FIG. 8, there was a significant decrease in the percentage of grey hair (FIG. 8, panel A, P<0.01) and a significant increase in the percentage of dark hair (FIG. 8, panel B, P<0.01) after 8 weeks of consumption, as well as a significant increase in the percentage of fine hair after 1 week of consumption (FIG. 8, panel C, P<0.05). As such, the composition of the present invention can promote hair growth, and delay hair graying at the same time. In addition, after 3 weeks of consumption, the skin firmness of the subjects was improved, as shown in FIG. 9.