PLUNGER AND FINGER GRIP FOR A SYRINGE ASSEMBLY, METHOD FOR MAKING THEM, SYRINGE ASSEMBLY, KIT AND USE OF THE SAME
20230302225 · 2023-09-28
Inventors
- Simon SCHMITT (Frankfurt am Main, DE)
- Uwe WORTMANN (Frankfurt am Main, DE)
- Dany Borowek (Frankfurt am Main, DE)
- Dirk NIPPRASCH (Frankfurt am Main, DE)
- Kai TIESBERGER (Bensheim, DE)
Cpc classification
A61M5/3137
HUMAN NECESSITIES
International classification
Abstract
The present invention relates to a plunger (20) and a finger grip (30) for a syringe assembly (100), methods for manufacturing them, to a syringe assembly (100), to a kit comprising parts of a syringe assembly (100), and to the use of a syringe assembly (100) or of a kit, wherein the syringe assembly (100) comprises a syringe barrel (10), a finger grip (30) having flanges (31, 32), and a plunger (20) having a plunger rod (21) and a plunger head (22). The plunger (20) comprises a grip pad (23) made by injection molding and attached to a proximal facing surface (24) of the plunger head. The finger grip (20) comprises a grip pad (35) also made by injection molding and attached to a distal facing surface of at least one flange (31, 32) of the finger grip (30).
Claims
1. A plunger for a syringe assembly for administering a liquid composition, wherein the plunger comprises a plunger rod and a plunger head, wherein the plunger rod comprises a proximal end and a distal end, and wherein the plunger head is attached to the proximal end of the plunger rod and comprises a proximal facing surface configured to serve as a thumb plate during administering, wherein the plunger comprises a grip pad attached to the proximal facing surface of the plunger head and extending at least partly over said proximal facing surface, wherein the grip pad is made by injection molding.
2. The plunger according to claim 1, wherein the grip pad on the plunger head is made of a thermoplastic elastomere (TPE), optionally a coloured thermoplastic elastomere (cTPE).
3. The plunger according to claim 1, wherein the proximal facing surface of the plunger head comprises at least one deepening, optionally at least one groove, which is filled by grip pad injection molding material.
4. The plunger according to claim 1, wherein the grip pad on the plunger head represents a symbol (“+”), optionally a letter or another character selected from the ASCII-Code.
5. The plunger according to claim 1, wherein the grip pad on the plunger head is made in one piece comprising one injection point only.
6. The plunger according to claim 1, wherein the plunger rod comprises at least one section in a longitudinal direction with an at least substantially double-T-profile shape, a double-T-profile-like shape, a I-profile shape or a I-profile-like shape.
7. A method for manufacturing a plunger according to claim 1, comprising at least: manufacturing the plunger head, forming the grip pad by injection molding.
8. A finger grip for a syringe assembly for administering a liquid composition, comprising a finger grip body with two flanges extending radially in opposite directions from a center bore in the finger grip body through which a plunger of a syringe assembly can be inserted, each flange serving as a grip portion and having a finger contact area onto which at least one finger of a user can be put partly during administering to support the finger whilst administering, wherein each flange comprises a distal facing surface and a proximal facing surface, wherein the finger grip comprises a grip pad attached to the distal facing surface of at least one of the flanges extending at least partly over said distal facing surface, wherein the grip pad is made by injection molding.
9. The finger grip according to claim 8, wherein at least one grip pad on the finger grip is made of a thermoplastic elastomere (TPE), optionally a coloured thermoplastic elastomere (cTPE).
10. The finger grip according to claim 8, wherein at least one grip pad on one of the finger grip flanges is made in one piece comprising one injection point only.
11. A method for manufacturing a finger grip according to claim 8, comprising at least: manufacturing a finger grip body including two flanges extending radially in opposite directions from a center bore (37) in the finger grip body (30) through which a plunger of a syringe assembly can be inserted, each flange serving as a grip portion and having a finger contact area onto which at least one finger of a user can be put partly during administering to support the finger whilst administering, wherein each flange comprises a distal facing surface and a proximal facing surface, and forming the grip pad by injection molding.
12. A syringe assembly for administering a liquid composition to a human or animal body, comprising at least: a longitudinal syringe barrel having an inner lumen for receiving and storing a liquid composition to be administered, a finger grip coupled to a proximal end of said barrel, and a plunger having a plunger rod and a plunger head, the plunger rod being disposed at least partly within the inner lumen of the barrel with a distal end thereof, wherein the plunger is a plunger according to claim 1 and/or the finger grip is a finger grip comprising a finger grip body through which the plunger of a syringe assembly can be inserted.
13. The syringe assembly according to claim 12, wherein the syringe barrel comprises a Luer lock connector at a distal end thereof integrally formed with the syringe barrel, wherein the syringe assembly further comprises a tip cap, the tip cap covering and sealing the distal end of the syringe barrel, wherein the tip cap is a two-part tip cap comprising a rigid part and an elastomeric part, wherein the maximum outer diameter (Dmax) of the rigid part is less or equal to the outer diameter of the Luer lock connector of the syringe barrel.
14. A kit comprising parts of a syringe assembly according to claim 12, configured to be assembled to a syringe assembly according to claim 12, wherein the kit comprises at least: a longitudinal syringe barrel having an inner lumen for receiving and storing a liquid composition to be administered, a finger grip configured to be coupled to a proximal end of said barrel, and a plunger having a plunger rod and a plunger head, wherein the plunger rod is configured to be disposed at least partly within the inner lumen of said barrel with thereof a distal end thereof, wherein the plunger is a plunger according to claim 1 and/or the finger grip is a finger grip comprising a finger grip body through which the plunger of a syringe assembly can be inserted.
15. A product comprising a syringe assembly according to claim 12 or a kit thereof for cosmetic or therapeutic application, optionally for replacing or filling a biological tissue or increasing volume of a biological tissue, wherein said product comprises an effective amount of a liquid composition, optionally an effective amount of a dermal filler composition, which is adapted to be administered to a subject.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0144] The accompanying drawings, which are incorporated herein and form a part of the specification, illustrate schematically preferred embodiments of the inventions described above, in particular of the present invention, and together with the description, serve to explain the principles and at least partly the features of the described inventions, wherein for same parts same reference signs are used. It is illustrated in:
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DETAILED DESCRIPTION OF SEVERAL EMBODIMENTS OF THE INVENTION
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[0167] The syringe assembly 100 further comprises a syringe barrel 10 having an inner lumen 13 (see e.g.
[0168] The plunger 20 can be moved into the syringe barrel 10 along a longitudinal axis A of said syringe barrel 10 for dispensing the composition stored in the inner lumen 13 (see e.g.
[0169] The plunger 20 comprises a plunger head 22 and a plunger rod 21 each made by injection molding of polypropylene PP, wherein the plunger head 22 and the plunger rod 21 are made in one piece. That means, they are integrally molded. The plunger head 22 comprises a proximal facing surface 24 onto which also by injection molding a grip pad 23 has been applied for facilitating gripping respectively for improving a contact of a user's thumb. The grip pad 23 is made of thermoplastic elastomere (TPE) which allows a safe and precise support of the thumb of a user during use of said syringe assembly 100 and therewith a precise administering of the composition stored in the syringe barrel 10.
[0170] In this example of a plunger 20 according to the present invention the grip pad 23 attached to the plunger head 22 is made in one piece via one injection point 26 only (see
[0171] Due to the fact that compositions as the hyaluronic acid dermal filler being stored in the syringe barrel 10 of syringe assembly 100 require high extrusion forces respectively high ejection forces because of their high viscosity, plunger rod 21 has to be resistive against kinking. To avoid mechanical failure of the plunger rod 21 during use, the plunger rod 21 has a double-mushroom shaped profile almost over its whole length, see also
[0172] The finger grip 30 comprises a finger grip body, also made by injection molding of polypropylene PP in one piece, having two flanges or wings 31 and 32 extending radially in opposite directions from a center bore 37 in the finger grip body. Through the center bore 37 the plunger 20 is inserted. The wings 31, 32 are extending to the right respectively to the left of the center bore 37. Each wing 31, 32 serves as a grip portion and has a finger contact area 35 onto which at least one finger of a user can be put partly during administering of the composition stored in the syringe barrel 10 to support the finger whilst administering, wherein each wing 31, 32 comprises a distal facing surface 33 and proximal facing surface 34.
[0173] According to the present invention, the finger grip 30 comprises at least one grip pad 35, in this example two grip pads 35, wherein each grip pad is attached to the distal facing surface 33 of one of the wings 31, 32 and extends almost over the whole distal facing surface 33. Both grip pads 35 are made by injection molding, wherein the grip pads 35 in this example of a finger grip 30 according to the present invention have been applied directly onto the distal facing surfaces 33 when injection molded.
[0174] The grip pads 35 attached to the flanges 31 and 32 also made of a thermoplastic elastomer (TPE) in one piece each having one injection point 26 (see
[0175] The grip pads 35 of the finger grip 30 also comprise areas 36 not being filled with grip pad injection molding material 35, wherein these areas are forming parallel and transversally extending stripes 36 completely being surrounded by grip pad material 35.
[0176] The finger grip 30 is coupled to the proximal end of the syringe barrel 10 by a flange 12 (see e.g.
[0177] For easy distinguishing and avoiding mis-administering of the composition stored in the syringe barrel 10 of the syringe assembly 100, the grip pad 23 attached to the plunger head 22 and the grip pads 35 attached to the finger grip body 30 respectively to its wings 31 and 32 are made of colored grip pad material, in particular of colored TPE, wherein the color is associated to that particular composition of a hyaluronic acid dermal filler stored in the syringe barrel 10. This allows a medical practitioner to recognize at the first glance which composition the respective syringe assembly 100 intended to be used contains.
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[0181] In particular from the illustration in
[0182] To achieve good adhesion between the grip pad 23 and the proximal facing surface 24 of the plunger head 22 and between the grip pads 35 and the distal facing surfaces 33 of the finger grip body 30, the surfaces to which the grip pads 23 respectively 35 are applied comprises several grooves 27, 39 each (see
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[0193] Like the plunger head grip pads 23 of the plunger 20 of the syringe assemblies 100 and 200 illustrated in
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[0197] The distal end of the syringe barrel 10 is closed and sealed by the tip cap 40, which comprises an outer rigid part 41, engaged with the inner threads of the Luer lock connector 11, and an inner elastomeric part 42, which is inserted into the outer rigid part 41 thereby closing and sealing the outlet channel 15 of the syringe barrel 10.
[0198] In this example, the maximum outer diameter Dmax of the rigid part 41 is less or equal to the outer diameter of the Luer connector 11 of the syringe barrel 11. Thereby a risk of unintended snagging or damage of the tip cap 40 and therewith of the closing and sealing of the prefilled syringe barrel 10 can be reduced. In particular, the outer wall of the rigid part is at least partly in flush with the outer wall of the Luer lock connector.
[0199] All of the features described herein with respect to one aspect of the present invention may also be realized alone or in combination in any other of the subjects according to any other aspect of the present invention, so far this is technically possible.
LIST OF REFERENCE SIGNS
[0200] 100 first example of an embodiment of a syringe assembly according to the present invention [0201] 200 second example of an embodiment of a syringe assembly according to the present invention [0202] 10 syringe barrel [0203] 11 Luer lock connector [0204] 12 flange of the syringe barrel at the proximal end of the syringe barrel [0205] 13 Luer cone of the Luer lock connector [0206] 15 outlet channel [0207] 20 example of an embodiment of a plunger according to the present invention [0208] 21 plunger rod [0209] 22 plunger head [0210] 23 grip pad of the plunger head [0211] 24 proximal facing surface of the plunger head [0212] 25 plunger tip at the distal end of the plunger rod [0213] 25A mushroom-shaped tip of the plunger rod [0214] 25B piston receiving portion [0215] 25C axial piston stop [0216] 26 injection point [0217] 27 groove in the proximal facing surface of the plunger head [0218] 30 example of an embodiment of the finger grip according to the present invention [0219] 31 right flange or wing of the finger grip body [0220] 32 left flange or wing of the finger grip body [0221] 33 distal facing surface of the finger grip body [0222] 34 proximal facing surface of the finger grip body [0223] 35 grip pad of the finger grip [0224] 36 area not being filled or covered by grip pad injection molding material of the [0225] finger grip designed as a stripe [0226] 37 center bore in the finger grip body [0227] 38 slot for finally insertion of a proximal flange of a syringe barrel [0228] 39 groove in the distal facing surface of the finger grip body [0229] 40 tip cap [0230] 41 rigid part of the tip cap (outer part) [0231] 42 elastomeric part of the tip cap (inner part) [0232] 50 piston [0233] 51 bottom side of the piston [0234] A longitudinal axis of the syringe barrel [0235] Dmax maximum outer diameter of the rigid part of the tip cap