ANTIMICROBIAL COSMETIC PREPARATION
20220023168 · 2022-01-27
Inventors
Cpc classification
A61K8/342
HUMAN NECESSITIES
A61K8/39
HUMAN NECESSITIES
A61P17/16
HUMAN NECESSITIES
International classification
Abstract
A water-based anti-microbial cosmetic preparation comprising 0.025% to 3.2% of silver-chitosan dispersion by weight and not more than 10% of a non-ionic surfactant by weight. The preparation has a ratio of non-ionic surfactant to silver chitosan by weight of at least 0.2:1 to allow the silver chitosan to form a film on the surface of the skin. The preparation has a pH of between 3 and 6.5 to ensure that the silver chitosan to ensure that the preparation is tolerable on the skin and to ensure that the silver does not precipitate. The preparation does not contain an ionic surfactant in order to avoid precipitating the silver chitosan out of the preparation.
Claims
1. A water-based anti-microbial cosmetic preparation comprising: 0.025% to 3.2% of silver-chitosan dispersion by weight; not more than 10% of a non-ionic surfactant by weight; and wherein: a ratio of non-ionic surfactant to silver chitosan by weight is at least 0.2:1; the preparation has a pH of between 3 and 6.5; and the preparation does not contain an ionic surfactant.
2. A cosmetic preparation according to claim 1, wherein the composition additionally comprises a pH modifier.
3. A cosmetic preparation according to claim 2, wherein the composition comprises one or more of sodium hydroxide, sodium bicarbonate, potassium hydroxide, triethanolamine, sodium phosphate, L-arginine, a high pH oil, and a high pH fragrance.
4. A cosmetic preparation according to claim 1, wherein the composition does not comprise any of a pH modifier or sodium hydroxide, sodium bicarbonate, potassium hydroxide, triethanolamine, sodium phosphate, L-arginine, a high pH oil, or a high pH fragrance.
5. A cosmetic preparation according to claim 1, wherein the non-ionic surfactant comprises one or more fatty alcohol ethoxylate, alkyl phenol ethoxylate, fatty acid alkoxylate or any non-ionic glyceryl stearate.
6. A cosmetic preparation according to claim 5, wherein the non-ionic surfactant comprises alcohol ethoxylate.
7. A cosmetic preparation according to claim 1 wherein the ratio of non-ionic surfactant to silver chitosan by weight is at least 0.5:1
8. A cosmetic preparation according to claim 7 wherein the ratio of non-ionic surfactant to silver chitosan by weight is at least 1.5:1.
9. A cosmetic preparation according to claim 1 further comprising one or more of a perfume, an oil, a viscosity modifier, a non-ionic emulsifier, glycerine, a thickener, and an emulsion stabiliser.
Description
EXAMPLE 1
[0036] The preparation of an antimicrobial hand cream according to the present invention is set out below.
[0037] Step 1
[0038] A first mixture consisting of: [0039] 100 g of 1% silver chitosan dispersion; [0040] 1 g phenoxyethanol ethylhexylglycerin (preservative); and [0041] 3 g alcohol ethoxylate (non-ionic surfactant)
[0042] is prepared and mixed thoroughly in a first container.
[0043] Step 2
[0044] A second mixture consisting of: [0045] 0.5 g xanthan gum (thickener); [0046] 30 g Sunflower oil (base); and [0047] 3 g glyceryl stearate (non-ionic surfactant)
[0048] is prepared and mixed thoroughly in a second container.
[0049] Step 3
[0050] The first mixture and the second mixture are combined, mixed thoroughly, and heated to a temperature of 70° C. to produce a third mixture.
[0051] Step 4
[0052] A fourth mixture consisting of [0053] 20 g cetearyl alcohol (emulsion stabiliser); and [0054] 2 g essential oil fragrance (perfume)
[0055] is prepared and mixed thoroughly in a third container.
[0056] Step 5
[0057] The fourth mixture is added to the third mixture and the combination is mixed until it cools and thickens to produce the anti-microbial hand cream.
[0058] This produces rich antimicrobial hand cream for use in treatment of cold weather dermatitis. The resulting hand cream has a pH of 4, which prevents the precipitation of the silver chitosan but is also well tolerated by the skin.
[0059] The ratio of non-ionic surfactant to silver chitosan by weight is 3:1. In particular, the composition contains 1 g of silver chitosan and 3 g of alcohol ethoxylate.
EXAMPLE 2
[0060] The following ingredients are mixed together to form a serum according to the present invention
[0061] Water −63% by weight of the total finished product
[0062] 1% silver chitosan dispersion to form 22% by weight
[0063] Glycerine 3.4%
[0064] Cetyl and Cetearyl Alcohol [non-ionic emulsifiers] 1.5%
[0065] Glyceryl Stearate [non-ionic surfactant] 1.7%
[0066] Cyclopentasiloxane [Oil for skin texture] 3.4%
[0067] Polyethylene Glycol Stearate also known as PEG 100 [non-ionic emulsifier] 1%
[0068] Dimethicone and Caprylic Triglyceride [Viscosity modifiers] 3.4%
[0069] Fragrances and Shea Butter for texture 0.6%.
EXAMPLE 3
[0070] The components of an antimicrobial serum according to the present invention are shown in the tables below. The silver chloride and chitosan provide the silver chitosan of the present invention whilst the Ceteareth-20 and the cetearyl alcohol are non-ionic surfactants.
TABLE-US-00001 No. substance w/w CAS No. 1 Aqua (water) 75.800 7732-18- 5 2 Cyclopentasiloxane 4.000 541-02-6 3 Caprylic Triglyceride 4.000 65381- 09-1 4 Glycerin 4.000 56-81-5 5 Dimethicone 2.000 9006-65- 9 6 Glyceryl Stearate 2.000 123-94-4 7 Ceteareth-20 1.750 68439- 49-6 8 Cetearyl Alcohol 1.750 8005-44- 5 9 PEG-100 Stearate 1.500 9004-99- 3 10 Triethanolamine 0.900 102-71-6 11 Phenoxyethanol 0.550 122-99-6 12 Ethylhexylglycerin 0.550 70445- 33-9 13 utyrospermum Parkii (Shea) Butter 0.500 91080- 23-8 14 Lactic Acid 0.200 50-21-5 15 Chitosan 0.180 9012-76- 4 16 Limonene 0.172 5989-27- 5 17 Allantoin 0.100 97-59-6 18 Citrus Tangerina (Tangerine) Peel Oil 0.050 223748- 44-5 19 Citrus Aurantium Bergamia (Bergamot) 0.050 8007-75- Fruit Oil 8 20 Citrus Grandis (Grapefruit) Peel Oil 0.050 8016-20- 4 21 Citrus Aurantium Dulcis (Orange) Peel 0.050 8008-57- Oil 9 22 Citral 0.009 5392-40- 5 23 Linalool 0.009 78-70-6 24 Silver Chloride 0.003 7783-90- 6 25 Citronellol 0.000 106-22-9 26 Geraniol 0.000 106-24-1
TABLE-US-00002 substance Purpose 1 Aqua Water as the main cosmetic base 2 Cyclopentasiloxane Silicon lubricant and solvent for other components 3 Caprylic Triglyceride Emollient and non ionic dispersing agent 4 Glycerin Skin smoothing agent 5 Dimethicone Viscoelastic agent and viscosity modifier 6 Glyceryl Stearate Non ionic Emulsifier and emollient skin softening agent 7 Ceteareth-20 Non ionic surfactant used as thickening agent 8 Cetearly Alcohol Non ionic surfactant for oil/water binding 9 PEG-100 Stearate Non ionic emulsifier for oil in water complexes 10 Triethanolamine Non ionic surfactant used as a pH buffer to raise pH 11 Phenoxyethanol Preservative and Biocide 12 Ethylhexylglycerin Non ionic preservative usually blended with phenoxyethanol 13 utyrospermum Parkii (Shea) primarily acts as an emollient and Butter smooths/softens the skin 14 Lactic Acid Solvent for the Chitosan 15 Chitosan carrier and complexing agent for the Silver additive 16 Limonene oil found in citrus fruit peel. Used as a fragrance 17 Allantoin a moisturiser with a Keratolytic effect. Used to soften Keratin in the skin 18 Citrus Tangerina (Tangerine) a fragrant oil of Tangerine Peel Oil 19 Citrus Aurantium Bergamia A fragrant oil of Bergamot (Bergamot) Fruit Oil 20 Citrus Grandis (Grapefruit) a fragrant oil of Grapefruit Peel Oil 21 Citrus Aurantium Dulcis a fragrant oil of Orange peel (Orange) Peel Oil 22 Citral a fragrance used again for its citrus effect 23 Linalool another fragrance with a sweet odour used with citrus fragrances 24 Silver Chloride Photochemically bound to the Chitosan to render it Antimicrobial 25 Citronellol Mosquito repellent at short distances 26 Geraniol Rose oil fragrance