ULTRA-THIN ACOUSTIC LENS FOR SUBWAVELENGTH FOCUSING IN MEGASONIC RANGE, AND DESIGN METHOD THEREFOR
20210366458 · 2021-11-25
Assignee
Inventors
- Jae-yub Hyun (Jeollabuk-do, KR)
- Yong-tae Kim (Daejeon, KR)
- Il Doh (Daejeon, KR)
- Bong-young Ahn (Daejeon, KR)
- Kyung-min Baik (Daejeon, KR)
- Se-hwa Kim (Daejeon, KR)
Cpc classification
A61B8/4483
HUMAN NECESSITIES
International classification
Abstract
The present invention relates to an ultra-thin acoustic lens for subwavelength focusing in a megasonic range and a design method thereof. More particularly, the present invention relates to a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in the megasonic range, which includes a plurality of concentric regions arranged in a concentric shape with reference to the center point, wherein the concentric regions include a plurality acoustic insulation region for insulating incident acoustic waves, and a plurality of transmission regions for transmitting acoustic waves, the acoustic insulation regions and the transmission regions being formed alternatively in a radial direction from the center point so as to focus incident acoustic wave energy onto a subwavelength region. The acoustic lens has flat surfaces on both sides thereof respectively and has a plate shape having a constant thickness, and a layout, which is a radius of each of the plurality of acoustic insulation regions and transmission regions in the concentric region, is determined by a topology optimization reverse design method.
Claims
1. A super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range, the super-oscillatory planar acoustic lens comprising: a plurality of concentric regions arranged in a concentric shape with reference to a center point, wherein the concentric regions are formed by crossing acoustic insulation regions for insulating incident acoustic waves and transmission regions for transmitting acoustic waves, in a radial direction from the center point, and focus the incident acoustic wave energy onto a subwavelength region, the acoustic lens is composed of opposite surfaces having a flat surface, and has a plate shape having a constant thickness, and a layout which is a radius of each of the plurality of acoustic insulation regions and transmission regions in the concentric region, is determined by a topology optimization reverse design method and provided being spaced apart from a transducer.
2. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 1, wherein the acoustic lens is composed of a binary ring mask-type super-oscillatory acoustic lens.
3. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 2, wherein during topology optimizing process, acoustic energy in a main focusing region is gradually increased, allowing optimization.
4. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 3, wherein the acoustic lens is provided being not attached to a transducer but spaced apart therefrom, allowing being replaced with other acoustic lenses having different, various layouts.
5. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 4, wherein an FWHM (Full Width at Half Maximum) in the main focusing region is a Rayleigh diffraction limit or under.
6. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 5, wherein the FWHM (Full Width at Half Maximum) in the main focusing region is 0.5λ/NA or under.
7. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 5, wherein a thickness of the acoustic lens is 0.5λ or under.
8. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 7, wherein a layout design of the acoustic insulation region and the transmission region is determined by following formula 2:
9. The super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 8, wherein according to updated design variables (γ.sub.e), material distribution in the design domain is determined on the basis of following formula 3a and formula 3b:
10. A design method of a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range, the design method of the super-oscillatory planar acoustic lens comprising steps of: determining a design domain for an optimal layout; setting up a desired main focusing region and determining a transmission material and an acoustic insulation material; setting up a desired FWHM and adopting a constraint; optimizing a layout of the transmission regions and the acoustic insulation region by a topology optimization reverse design method; and fabricating an acoustic lens through a photo etching method on the basis of the optimized layout.
11. The design method of a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 10, wherein during topology optimizing process, acoustic energy is gradually increased in a main focusing region, allowing optimization.
12. The design method of a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 11, wherein a layout design of the acoustic insulation region and the transmission region is determined by following formula 2:
13. The design method of a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 12, wherein according to updated design variables (γ.sub.e), material distribution in the design domain is determined on the basis of following formula 3a and formula 3b:
14. The design method of a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 13, wherein during optimizing process, the design variables are updated on the basis of slope information calculated by AVM (Adjoint Variable Method).
15. The design method of a super-oscillatory planar ultra-thin acoustic lens for subwavelength focusing in a megasonic range according to claim 14, wherein during the optimizing process, a heaviside projection filtering method having beta-continuation is repeated.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0046] The accompanying drawings of this specification exemplify a preferred embodiment of the present disclosure, the spirit of the present disclosure will be more clearly understood from the following detailed description taken in conjunction with the accompanying drawings, and thus it will be understood that the present disclosure is not limited to only contents illustrated in the accompanying drawings.
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DETAILED DESCRIPTION
Best Mode
[0058] Hereinafter, described are the proof of a super-oscillatory phenomenon and the application thereof to a subwavelength focusing acoustic lens. The super-oscillatory mechanism of a megasonic super-oscillatory acoustic lens provided in the present invention can be proved simply in a one dimensional (1D) wave composed of six domains of Fourier components according to an approaching method. A 1D waveform can be defined as f(r) in Formula 1.
[0059] in the formula 1, r is a radius of a source transducer, meaning a normalized position along with the lateral direction. Herein, An uses a Fourier coefficient (wherein, A.sub.0=19.0123, A1=−2.7348, A.sub.2=−15.7629, A.sub.3=−17.9047, A.sub.4=−1.0000, A.sub.5=18,4910).
[0060]
[0061] That is, in
[0062] Herein, the wording “the fastest” means an oscillatory component being the fastest spatially by the highest frequency component of the original waveform. As shown in the lower panel in
[0063] In this 1D, super-oscillation means a waveform which oscillates faster than the highest harmonic frequency component of the original wave in a limited interval (i.e., desired main focusing region). Therefore, a subwavelength focusing feature is guaranteed only in this finite region. As shown in this D1, super-oscillatory phenomenon-based subwavelength focusing can be accomplished as controlling an amplitude (Fourier coefficient) and a phase (2 πnr) of the waveform diffracted from a micro-slit of the lens.
[0064] Meanwhile, the subwavelength feature of the super-oscillatory wave should involve a high amplitude region outside the desired main focusing region. An undesired region is referred to as a side lobe. In order to improve the focusing performance (i.e., narrower FWHM) of the lens, the undesirable side lobe is an unavoidable result, since the relationship between the desired region and the undesired region has a trade-off performance. Therefore, it is needed to select an appropriate scale of the desired main focusing region in order to practically design the SOAL.
[0065] As shown in
[0066] Moving on to the next, in order to design an optimal layout of the binary ring mask-type SOAL, described is an optimization formula capable of quantification physically.
[0067] Since a design optimizing process according to the present invention allows phase changes such as increases or decreases in the number of holes, applied was topology optimization as one of the most flexible type of reverse design methods.
[0068] In order to obtain the optimal layout of the binary ring mask-type SOAL, a numerical model should be taken into account for both analysis and design.
[0069] In
[0070] The radius and height of the design domain (i.e., thickness of SOAL) are 30 mm and 0.2 mm, respectively. Then, the desired main focusing region (i.e., red-semicircular target bright zone in
[0071] Meanwhile, in order to topologically design the binary ring mask-type SOAL for subwavelength focusing, it is needed to take the side lobe into account besides the main focusing region, with maintaining a band-limited feature of the main focusing region (i.e., red-semicircular target bright zone in
[0072] wherein, p is an acoustic pressure, and γ.sub.e is a design variable which is varied in an interval of 0 to 1 during phase optimization. VFF is an essential volume ratio which defines a ratio of an opaque region to an entire design domain. V.sub.design is a volume of the entire design domain. e is a threshold for relaxation of a constraint (g.sub.2). In the embodiment of the present invention, 10.sup.−3 is selected as this value. NE is the sum of design variables. Herein, according to updated design variables (γ.sub.e), material distribution in the design domain can be determined on the basis of following formula 3a and formula 3b. When γ.sub.e=0, an acoustic material corresponds to water (i.e., acoustically transparent region), while corresponding to SUS303 (i.e., acoustic insulation region) when γ.sub.e=1.
[0073] wherein, q.sup.1 AND q.sup.2 are penalty coefficients for a mass density (ρ) and an acoustic speed (c), respectively. These penalty coefficients are used for increasing a convergence speed of the optimizing process. 1.5 is selected as these values in the embodiment of the present invention. MMA (Moving Asysmptotes) method is used as the following optimizing algorithm.
[0074] This type of optimizing algorithm requires the first-order differentiation (i.e., gradient) information of a target function called a design sensitivity threshold in order to update the design variables. Therefore, in the present invention, in order to calculate this gradient information, effective design sensitivity analysis is carried out on the basis of Adjoint Variable Method (AVM).
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[0076] Accordingly, the target function (i.e., acoustic energy J.sub.AE.sup.bright) slightly jumps at every fiftieth time as shown in the topology optimization history (
DESCRIPTION OF EMBODIMENTS
[0077] Hereinafter, described is an experimental result for subwavelength focusing of an optimized super-oscillatory acoustic lens (SOAL) according to an embodiment of the present invention. In order to examine a subwavelength focusing performance of the optimized SOAL, a circular form was fabricated through photo etching, then performing an experiment to measure an acoustic field radiated from the optimized SOAL using an acoustic intensity measurement system. The subwavelength focusing performance of the optimized SOAL was examined as compared to a conventional FZP lens having the same primary focal length (i.e., position of a desired main focusing region) as that of the optimized SOAL. A layout of the conventional FZP lens having the primary focal length (F) can be obtained by using the following formula 4.
[0078] wherein, b.sub.n is a radius of the n.sub.th circular region. N=1, 2, . . . N, wherein N is the total number of regions. F is a main focal length, λ is a used acoustic wavelength. The conventional FZP acoustic lens and the optimized SOAL according to the present invention were fabricated by using photo etching as shown in
[0079] As shown in
[0080] An apparatus for the experiment according to the example of the present invention as shown in
[0081] A needle-type hydrophone (Precision Acoustics) in which an underwater pre-amplifier was equipped and a radius of the needle is 500 μm is used in accurately measuring the acoustic filed through an acoustic lens. Further, in order to generate a fifteen cycle tone-burst signal of 1 MHz to 200 mV.sub.rms, an arbitrary waveform generator (33250A, Agilent Technologies) was used. In order to amplify the generated tone-burst signal, an RF amplifier (2100 L RF amplifier, Electronics & Innovation, Ltd.) was used. The whole equipment was installed to a deionized and degasified tank, then measuring the acoustic field passing through the acoustic lens with an acoustic intensity measurement system (AIMS III with Soniq Software, ONDA).
[0082] Prior to indicating an experimentally measured result, a numerically calculated result should be provided first.
[0083] In the embodiment of the present invention, a Finite Element Method (FEM) based on commercial software, COMSOL Multiphysics and MATLAB was used in then numerical analysis and design optimization of the SOAL. Materials used in the simulation were water and SUS 303. Time-harmonic analysis is used in calculating the acoustic field through the optimized SOAL. The secondary Sommerfeld absorbing boundary conditions are set up in the external boundary of a simulation region in order to remove boundary reflected acoustic waves. The source transducer approximates a plane wave boundary condition. The largest scale of a mesh element is set up being smaller than 1/10 of wavelength.
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[0085] Measurement values are made on an XZ-scanning plane (i.e., 40 mm×40 mm) of
[0086] A cross-sectional line for plotting is indicated as a broken line. As mentioned above, in order to accurately evaluate the subwavelength focusing performance of the optimized SOAL, NA should be taken into account. NA is determined by a radius of an input source transducer (r.sub.source) and a designated basic focal length (F) and represented as NA=sin (tan.sup.−1(r.sub.source/F)). NA for the optimized SOAL having a monolayer according to the embodiment of the present invention is approximately 0.707. Therefore, the focusing limit of the conventional acoustic lens (i.e., Rayleigh diffraction limit) is 0.61λ/NA≈0.86λ≈1.28 mm.
[0087] The numerical and experimental results in
TABLE-US-00001 TABLE 1 Rayleigh diffraction Numerically Experimentally limit calculated measured (The focusing FWHM FWHM limit) Conventional 1.24 1.37 1.28 FZP lens Optimized SOAL 0.78 0.84
[0088] (1) FWHM (0.40λ/NA≈0.57λ≈0.84 mm) is narrow as compared to the conventional FZP lens (0.64λ/NA≈0.91λ≈1.37 mm), (2) the Rayleigh diffraction limit (0.61λ/NA≈0.86λ≈1.28 mm) can be overcome, then obtaining subwavelength focusing (0.40λ/NA≈0.57λ≈0.84 mm). Meanwhile, the optimized SOAL has an extremely narrow acoustic passing region (i.e., micro-slit). In practice, this causes a thermal-viscous loss, resulting in a damping effect. Herein, the narrowest acoustic passing region (˜0.29 mm) of the optimized region is larger than a thickness of a thermal (δ.sub.thermal˜0.21 μm) and viscous (δ.sub.viscous˜0.56 μm) layer estimated from a simple analysis equation. Thus, the thermal-viscous loss effect can be ignored at 20° C. and 1 atm.
[0089] However, in order to achieve a SOAL having side FWHM which is much narrower than the optimized SOAL according to the embodiment of the present invention, a narrower micro slit should be fabricated under proper uncertainty. Since the loss maximized by this narrow micro slit may affect the performance of the SOAL significantly, the optimizing process should take a complete combination model of the thermal and acoustic field into account.
[0090] In conclusion, in the embodiment of the present invention, optimized was a subminiature SOAL having the subwavelength focusing function which was capable of focusing incident acoustic energy on the subwavelength region. In order to design the optimal SOAL layout topologically, applied was the reverse design method referred to as topology optimization. As utilizing the reverse design methodology proposed in the embodiment of the present invention, the SOAL was designed, allowing maximizing the focusing performance of acoustic energy in the viewpoint of FWHM.
[0091] Further, the embodiment of the present invention proved that the SOAL optimized by experimentally embodying the SOAL overcome the diffraction limit, achieving subwavelength focusing. Meanwhile, for practical diagnosis and treatment processes rather than clinical situation, acoustic energy should be focused on a position far from the acoustic lens (i.e., z>>λ). That is, the acoustic lens should have a long focal length. The optimized SOAL allows focusing acoustic energy on a position being approximately 16λ, thus supplementing the drawback of a short-field imaging approach method including several AMM based Lenses. There is still a problem to be solved in connection with the thermal-viscous loss effect resulted from an extremely narrow micro-slit, however, the optimized SOAL has a great advantage in pragmatic aspect.
[0092] Further, the optimized SOAL according to the present invention provides diverse advantages such as low-power therapy, the far-field focus of a long focal length and focal length control through replacement with the optimized SOAL, thus improving therapeutic performance of High Intensity Focused Ultrasound (HIFU)/High Intensity Therapeutic Ultrasound (HITU). Further, in order to achieve an acoustic imaging of super-resolution in practice, the optimized SOAL can be applied to an acoustic microscope. Further, the concept of the optimized SOAL may be extended to a variety of wave (elasticity, sound, light wave) based systems through a similar design program to that proposed in the embodiment of the present invention.
[0093] Further, the configuration and method of the embodiments as described above are not restrictively applied to the aforementioned apparatus and method. The whole or part of the respective embodiments may be selectively combined so as to make various modifications of the embodiments.