Spinal interbody implants

Abstract

Spinal interbody fusion implants for use in posterior lumbar interbody fusions (PLIF), anterior lumbar interbody fusions (ALIF), transforaminal lumbar interbody fusions (TLIF) and transpsoas interbody fusions (DLIF), each of the implants including a 3-D printed titanium frame having meshed sidewalls, open top and bottom faces and a selectively closeable back plate for enclosing a posterior end of the frame. A machined, acid treated allograft bone graft is contained within the frame, the bone graft having a window for containing a biomaterial, anti-migration teeth and a ridge configured to mate with a slot within the frame for locking the graft in the frame.

Claims

1. A spinal implant comprising: a 3-D printed titanium enclosure including, a first sidewall, a first mesh window extending through the first sidewall, a second sidewall opposing the first sidewall, a second mesh window extending through the second sidewall, a substantially convex third sidewall extending to and between the first sidewall and the second sidewall, the third sidewall forming a first end of the enclosure, a second end opposite the first end, a fourth sidewall opposing the third sidewall and hingedly coupled to the first sidewall and detachably coupled to the second sidewall, a longitudinal axis extending through a center of the third sidewall and a center of the fourth sidewall, a substantially U-shaped top wall with a substantially U-shaped top opening there through, and a substantially U-shaped bottom wall with a substantially U-shaped bottom opening there through, wherein the first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot having an upper seat portion and a lower seat portion, and a CNC machined, acid treated allograft bone graft including, a first face, a second face opposing the first face, a substantially convex third face extending to and between the first face and the second face, wherein the longitudinal axis extends through a center of the third face, a fourth face opposing the third face having a substantially cross-shaped cross-section, wherein the longitudinal axis extends through a center of the fourth face, a top face including anti-migration ridges, a bottom face including anti-migration ridges, and a hole extending to and between the top face and the bottom face, wherein the first face, the second face and the third face form a substantially U-shaped face including a substantially U-shaped protrusion extending along a length of the U-shaped face and defining a graft upper ledge and a graft lower ledge, wherein the allograft bone graft is contained within the enclosure with the a graft upper ledge engaged with the upper seat portion and the graft lower ledge engaged with the lower seat portion.

2. The implant of claim 1 wherein the top face and the bottom face taper inwardly toward the longitudinal axis at the first end of the enclosure.

3. The implant of claim 1 wherein the first sidewall and the second sidewall are parallel.

4. The implant of claim 1 wherein the top face and the bottom face are convex.

5. The implant of claim 1 wherein the top face extends out of the enclosure through the top opening and the bottom face extends out of the enclosure through the bottom opening.

6. The implant of claim 1 wherein the fourth sidewall is fabricated from nickel titanium alloy or cobalt.

7. The implant of claim 1 including a biomaterial contained within the hole extending to and between the top face and the bottom face.

8. The implant of claim 1 wherein the first sidewall is convex and the second sidewall is concave.

9. The implant of claim 1 wherein the first face is convex and the second face is concave.

10. The implant of claim 1 wherein the allograft bone graft is pre-hydrated.

11. The implant of claim 1 wherein the first sidewall, the second sidewall, the third sidewall, the top wall and the bottom wall are porous.

12. The implant of claim 1 wherein the first sidewall and the second sidewall taper inwardly towards the longitudinal axis at the second end of the enclosure.

13. The implant of claim 1 wherein the first face and the second face taper inwardly towards the longitudinal axis at the second end of the enclosure.

14. The implant of claim 1 wherein the top face and the bottom face are parallel.

15. The implant of claim 1 including a third mesh window extending through the first sidewall and a fourth mesh window extending through the second sidewall.

16. The implant of claim 1 including a second hole extending to and between the top face and the bottom face.

17. A surgical method for vertebral interbody fusion comprising: inserting the implant of claim 1 between a first vertebra and a second vertebra, wherein the surgical method is a surgical procedure selected from the group consisting of a posterior lumbar interbody fusion (PLIF) procedure, an anterior lumbar interbody fusion (ALIF) procedure, a transforaminal lumbar interbody fusion (TLIF) procedure and a transpsoas interbody fusions (DLIF) procedure.

18. A spinal implant comprising: an enclosure including, a first sidewall, a first mesh window extending through the first sidewall, a second sidewall opposing the first sidewall, a second mesh window extending through the second sidewall, a substantially convex third sidewall extending to and between the first sidewall and the second sidewall, the third sidewall forming a first end of the enclosure, a second end opposite the first end, a fourth sidewall opposing the third sidewall and hingedly coupled to the first sidewall and detachably coupled to the second sidewall, a longitudinal axis extending through a center of the third sidewall and a center of the fourth sidewall, a substantially U-shaped top wall with a substantially U-shaped top opening there through, and a substantially U-shaped bottom wall with a substantially U-shaped bottom opening there through, wherein the first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot having an upper seat portion and a lower seat portion.

19. The implant of claim 18 including, an allograft bone graft including, a first face, a second face opposing the first face, a substantially convex third face extending to and between the first face and the second face, wherein the longitudinal axis extends through a center of the third face, a fourth face opposing the third face having a substantially cross-shaped cross-section, wherein the longitudinal axis extends through a center of the fourth face, a top face including anti-migration ridges, a bottom face including anti-migration ridges, and a hole extending to and between the top face and the bottom face, wherein the first face, the second face and the third face form a substantially U-shaped face including a substantially U-shaped protrusion extending along a length of the U-shaped face and defining a graft upper ledge and a graft lower ledge, wherein the allograft bone graft is contained within the enclosure with the a graft upper ledge engaged with the upper seat portion and the graft lower ledge engaged with the lower seat portion.

20. A spinal implant comprising: a first mesh window extending through a first sidewall, a second mesh window extending through a second sidewall, a substantially convex third sidewall extending to and between the first sidewall and the second sidewall, the third sidewall forming a first end of the spinal implant, a second end opposite the first end, a fourth sidewall opposing the third sidewall and hingedly coupled to the first sidewall and detachably coupled to the second sidewall, a substantially U-shaped top wall with a substantially U-shaped top opening there through, and a substantially U-shaped bottom wall with a substantially U-shaped bottom opening there through, wherein the first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot, and an allograft bone graft enclosed within the spinal implant.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

(1) FIGS. 1 through 7 depict a PLIF procedure in accordance with the prior art.

(2) FIGS. 8 through 15 depict a TLIF procedure in accordance with the prior art.

(3) FIGS. 16 through 24 depict an ALIF procedure in accordance with the prior art.

(4) FIGS. 25 through 30 depict a DLIF procedure in accordance with the prior art.

(5) FIG. 31 is a perspective view of an anterior end of a PLIF implant illustrating an allograft bone graft contained with a cage.

(6) FIG. 32 is a perspective view of a posterior end of the PLIF implant of FIG. 31.

(7) FIG. 33 is a elevational view of an anterior end of the cage of the PLIF implant of FIG. 31.

(8) FIG. 34 is a elevational view of a lateral side of the cage of FIG. 33.

(9) FIG. 35 is a elevational view of a posterior end of cage of FIG. 33.

(10) FIG. 36 is a top plan view of the cage of FIG. 33.

(11) FIG. 37 is a perspective view of the cage of FIG. 33.

(12) FIG. 38 is a elevational view of an anterior end of the graft of the PLIF implant of FIG. 31.

(13) FIG. 39 is a elevational view of a lateral side of the graft of FIG. 38.

(14) FIG. 40 is a elevational view of a posterior end of graft of FIG. 38.

(15) FIG. 41 is a top plan view of the graft of FIG. 38.

(16) FIG. 42 is a perspective view of the graft of FIG. 38.

(17) FIG. 43 is an exploded perspective view of the posterior end of the PLIF implant of FIG. 31.

(18) FIG. 44 is a elevational view of an anterior end of the PLIF implant of FIG. 31.

(19) FIG. 45 is a elevational view of a lateral side of the PLIF implant of FIG. 31.

(20) FIG. 46 is a elevational view of a posterior end of PLIF implant of FIG. 31.

(21) FIG. 47 is a top plan view of the PLIF implant of FIG. 31.

(22) FIG. 48 is a perspective view of an anterior end of a TLIF implant illustrating an allograft bone graft contained with a cage.

(23) FIG. 49 is a perspective view of a posterior end of the TLIF implant of FIG. 48.

(24) FIG. 50 is a elevational view of an anterior end of the cage of the TLIF implant of FIG. 48.

(25) FIG. 51 is a elevational view of a lateral side of the cage of FIG. 50.

(26) FIG. 52 is a elevational view of a posterior end of cage of FIG. 50.

(27) FIG. 53 is a top plan view of the cage of FIG. 50.

(28) FIG. 54 is a perspective view of the cage of FIG. 50.

(29) FIG. 55 is a elevational view of an anterior end of the graft of the TLIF implant of FIG. 48.

(30) FIG. 56 is a elevational view of a lateral side of the graft of FIG. 55.

(31) FIG. 57 is a elevational view of a posterior end of graft of FIG. 55.

(32) FIG. 58 is a top plan view of the graft of FIG. 55.

(33) FIG. 59 is a perspective view of the graft of FIG. 55.

(34) FIG. 60 is an exploded perspective view the posterior end of the TLIF implant of FIG. 48.

(35) FIG. 61 is a elevational view of THE anterior end of the TLIF implant of FIG. 48.

(36) FIG. 62 is a elevational view of a lateral side of the TLIF implant of FIG. 48.

(37) FIG. 63 is a elevational view of a posterior end of TLIF implant of FIG. 48.

(38) FIG. 64 is a top plan view of the TLIF implant of FIG. 48.

(39) FIG. 65 is a perspective view of an anterior end of a ALIF implant illustrating an allograft bone graft contained with a cage.

(40) FIG. 66 is a perspective view of a posterior end of the ALIF implant of FIG. 65.

(41) FIG. 67 is a elevational view of an anterior end of the cage of the ALIF implant of FIG. 65.

(42) FIG. 68 is a elevational view of a lateral side of the cage of FIG. 67.

(43) FIG. 69 is a elevational view of a posterior end of cage of FIG. 67.

(44) FIG. 70 is a top plan view of the cage of FIG. 67.

(45) FIG. 71 is a perspective view of the cage of FIG. 67.

(46) FIG. 72 is a elevational view of an anterior end of the graft of the ALIF implant of FIG. 65.

(47) FIG. 73 is a elevational view of a lateral side of the graft of FIG. 72.

(48) FIG. 74 is a elevational view of a posterior end of graft of FIG. 72.

(49) FIG. 75 is a top plan view of the graft of FIG. 72.

(50) FIG. 76 is a perspective view of the graft of FIG. 72.

(51) FIG. 77 is an exploded perspective view the posterior end of the ALIF implant of FIG. 65.

(52) FIG. 78 is a elevational view of THE anterior end of the ALIF implant of FIG. 65.

(53) FIG. 79 is a elevational view of a lateral side of the ALIF implant of FIG. 65.

(54) FIG. 80 is a elevational view of a posterior end of ALIF implant of FIG. 65.

(55) FIG. 81 is a top plan view of the ALIF implant of FIG. 65.

(56) FIG. 82 is a perspective view of an anterior end of a DLIF implant illustrating an allograft bone graft contained with a cage.

(57) FIG. 83 is a perspective view of a posterior end of the DLIF implant of FIG. 82.

(58) FIG. 84 is a elevational view of an anterior end of the cage of the DLIF implant of FIG. 82.

(59) FIG. 85 is a elevational view of a lateral side of the cage of FIG. 84.

(60) FIG. 86 is a elevational view of a posterior end of cage of FIG. 84.

(61) FIG. 87 is a top plan view of the cage of FIG. 84.

(62) FIG. 88 is a perspective view of the cage of FIG. 84.

(63) FIG. 89 is a elevational view of an anterior end of the graft of the DLIF implant of FIG. 82.

(64) FIG. 90 is a elevational view of a lateral side of the graft of FIG. 89.

(65) FIG. 91 is a elevational view of a posterior end of graft of FIG. 89.

(66) FIG. 92 is a top plan view of the graft of FIG. 89.

(67) FIG. 93 is a perspective view of the graft of FIG. 89.

(68) FIG. 94 is an exploded perspective view the posterior end of the DLIF implant of FIG. 82.

(69) FIG. 95 is a elevational view of the anterior end of the DLIF implant of FIG. 82.

(70) FIG. 96 is a elevational view of a lateral side of the DLIF implant of FIG. 82.

(71) FIG. 97 is a elevational view of a posterior end of DLIF implant of FIG. 82.

(72) FIG. 98 is a top plan view of the DLIF implant of FIG. 82.

DETAILED DESCRIPTION

(73) The present invention is directed to spinal interbody fusion implants for use in posterior lumbar interbody fusions (PLIF), anterior lumbar interbody fusions (ALIF), transforaminal lumbar interbody fusions (TLIF) and transpsoas interbody fusions (DLIF). FIGS. 31 through 47 depict a PLIF implant 100 in accordance with a first embodiment of the present invention. FIGS. 48 through 64 depict a TLIF implant 200 in accordance with a second embodiment of the present invention. FIGS. 65 through 81 depict an ALIF implant 300 in accordance with a third embodiment of the present invention, and FIGS. 82 through 98 depict a DLIF implant 400 in accordance with a fourth embodiment of the present invention. FIGS. 1 through 7 depict a PLIF procedure in accordance with the prior art with which PLIF implant 100 may be implemented. FIGS. 8 through 15 depict a TLIF procedure in accordance with the prior art with which TLIF implant 200 may be implemented. FIGS. 16 through 24 depict an ALIF procedure in accordance with the prior art with which ALIF implant 300 may be implemented, and FIGS. 25 through 30 depict a DLIF procedure in accordance with the prior art with which DLIF implant 400 may be implemented. Generally, the spinal interbody fusion implants of the present invention include a 3-D printed titanium frame having meshed sidewalls, open top and bottom faces and a selectively closeable back plate for enclosing a posterior end of the frame. A machined, acid treated allograft bone graft is contained within the frame, the bone graft having a window for containing a biomaterial, anti-migration teeth and a ridge configured to mate with a slot within the frame for locking the graft in the frame.

(74) PLIF

(75) More particularly, referring to FIGS. 31 through 47, PLIF implant 100 includes a 3-D printed titanium enclosure 110 having a first sidewall 112, a first mesh window 114 extending through the first sidewall, a second sidewall 116 opposing the first sidewall, a second mesh window 118 extending through the second sidewall, a substantially convex third sidewall 120 extending to and between the first sidewall and the second sidewall, the third sidewall 120 forming a first end 124 of the enclosure, a second end 126 opposite the first end, a fourth sidewall 128 opposing the third sidewall and hingedly coupled to the second sidewall and detachably coupled to the first sidewall, a longitudinal axis extending through a center of the third sidewall and a center of the fourth sidewall, a substantially U-shaped top wall 130 with a substantially U-shaped top opening 132 there through, and a substantially U-shaped bottom wall 134 with a substantially U-shaped bottom opening 136 there through. The first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot 138 having an upper seat portion 140 and a lower seat portion 142. As depicted in FIGS. 33 and 34, top wall 130 and bottom wall 134 taper inwardly toward first end 124.

(76) PLIF allograft bone graft 150 includes a substantially convex first face 152, a substantially convex second face 154 opposing the first face, a substantially convex third face 156 extending to and between the first face and the second face, wherein the longitudinal axis extends through a center of the third face, a fourth face 158 opposing the third face having a substantially cross-shaped cross-section, wherein the longitudinal axis extends through a center of the fourth face, a top face 160 including anti-migration ridges 162, a bottom face 164 including anti-migration ridges 162, and a hole 166 extending to and between the top face and the bottom face. The first face, the second face and the third face form a substantially U-shaped face including a substantially U-shaped protrusion 168 extending along a length of the U-shaped face and defining a graft upper ledge 170 and a graft lower ledge 172.

(77) In use, fourth sidewall 128 is pivoted open, and PLIF allograft bone graft 150 is inserted into enclosure 110 through the open doorway with the a graft upper ledge 170 engaged with the upper seat portion 140 and the graft lower ledge 172 engaged with the lower seat portion 142. Fourth sidewall 128 is then closed and fixed shut. Once assembled, PLIF implant 100 may be used to fuse adjacent vertebra according to the method illustrated in FIGS. 1 through 7 and described above, with top and bottom faces 160, 164 protruding out through U-shaped slot 138 so that anti-migration ridges 162 may directly contact adjacent the vertebrae.

(78) TLIF

(79) Referring to FIGS. 48 through 64, TLIF implant 200 includes a 3-D printed titanium enclosure 210 having a substantially convex first sidewall 212, a first mesh window 214 extending through the first sidewall, a substantially concave second sidewall 216 opposing the first sidewall, a second mesh window 218 extending through the second sidewall, a substantially convex third sidewall 220 extending to and between the first sidewall and the second sidewall, the third sidewall 220 forming a first end 224 of the enclosure, a second end 226 opposite the first end, a fourth sidewall 228 opposing the third sidewall and hingedly coupled to the second sidewall and detachably coupled to the first sidewall, a substantially U-shaped top wall 230 with a substantially U-shaped top opening 232 there through, and a substantially U-shaped bottom wall 234 with a substantially U-shaped bottom opening 236 there through. The first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot 238 having an upper seat portion 240 and a lower seat portion 242.

(80) TLIF allograft bone graft 250 includes a substantially convex first face 252, a substantially concave second face 254 opposing the first face, a substantially convex third face 256 extending to and between the first face and the second face, a fourth face 258 opposing the third face having a substantially cross-shaped cross-section, a substantially convex top face 260 including anti-migration ridges 262, a substantially convex bottom face 264 including anti-migration ridges 262, and a hole 266 extending to and between the top face and the bottom face. The first face, the second face and the third face form a substantially U-shaped face including a substantially U-shaped protrusion 268 extending along a length of the U-shaped face and defining a graft upper ledge 270 and a graft lower ledge 272.

(81) In use, fourth sidewall 228 is pivoted open, and TLIF allograft bone graft 250 is inserted into enclosure 210 through the open doorway with the a graft upper ledge 270 engaged with the upper seat portion 1240 and the graft lower ledge 272 engaged with the lower seat portion 242. Fourth sidewall 228 is then closed and fixed shut. Once assembled, TLIF implant 200 may be used to fuse adjacent vertebra according to the method illustrated in FIGS. 8 through 15 and described above, with top and bottom faces 260, 264 protruding out through U-shaped slot 238 so that anti-migration ridges 262 may directly contact adjacent the vertebrae.

(82) ALIF

(83) Referring to FIGS. 65 through 81, ALIF implant 300 includes a 3-D printed titanium enclosure 310 having a first sidewall 312, a first mesh window 314 extending through the first sidewall, a second sidewall 316 opposing the first sidewall, a second mesh window 318 extending through the second sidewall, a substantially convex third sidewall 320 extending to and between the first sidewall and the second sidewall, the third sidewall 320 forming a first end 324 of the enclosure, a second end 326 opposite the first end, a fourth sidewall 328 opposing the third sidewall and hingedly coupled to the second sidewall and detachably coupled to the first sidewall, a longitudinal axis extending through a center of the third sidewall and a center of the fourth sidewall, a substantially U-shaped top wall 330 with a substantially U-shaped top opening 332 there through, and a substantially U-shaped bottom wall 334 with a substantially U-shaped bottom opening 336 there through. The first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot 338 having an upper seat portion 340 and a lower seat portion 342. U-shaped slot 338 has a width defined between sidewall 312, 316 that tapers inwardly from first end to 324 to second end 326.

(84) ALIF allograft bone graft 350 includes a first face 352, a second face 354 opposing the first face, a substantially convex third face 356 extending to and between the first face and the second face, wherein the longitudinal axis extends through a center of the third face, a fourth face 358 opposing the third face having a substantially cross-shaped cross-section, wherein the longitudinal axis extends through a center of the fourth face, a top face 360 including anti-migration ridges 362, a bottom face 364 including anti-migration ridges 362, and a hole 366 extending to and between the top face and the bottom face. The first face, the second face and the third face form a substantially U-shaped face including a substantially U-shaped protrusion 368 extending along a length of the U-shaped face and defining a graft upper ledge 370 and a graft lower ledge 372.

(85) In use, fourth sidewall 1328 is pivoted open, and ALIF allograft bone graft 350 is inserted into enclosure 310 through the open doorway with the a graft upper ledge 370 engaged with the upper seat portion 340 and the graft lower ledge 372 engaged with the lower seat portion 342. Fourth sidewall 328 is then closed and fixed shut. Once assembled, ALIF implant 300 may be used to fuse adjacent vertebra according to the method illustrated in FIGS. 16 through 24 and described above, with top and bottom faces 360, 364 protruding out through U-shaped slot 338 so that anti-migration ridges 362 may directly contact adjacent the vertebrae.

(86) DLIF

(87) Referring to FIGS. 82 through 98, DLIF implant 400 includes a 3-D printed titanium enclosure 410 having a first sidewall 412, a pair of first mesh windows 414 extending through the first sidewall, a second sidewall 416 opposing the first sidewall, a pair of second mesh windows 418 extending through the second sidewall, a substantially convex third sidewall 420 extending to and between the first sidewall and the second sidewall, the third sidewall 420 forming a first end 424 of the enclosure, a second end 426 opposite the first end, a fourth sidewall 428 opposing the third sidewall and hingedly coupled to the second sidewall and detachably coupled to the first sidewall, a longitudinal axis extending through a center of the third sidewall and a center of the fourth sidewall, a substantially U-shaped top wall 430 with a substantially U-shaped top opening 432 there through, and a substantially U-shaped bottom wall 434 with a substantially U-shaped bottom opening 436 there through. The first sidewall, the second sidewall and the third sidewall form a substantially U-shaped sidewall defining a substantially U-shaped slot 438 having an upper seat portion 440 and a lower seat portion 442.

(88) DLIF allograft bone graft 450 includes a first face 452, a second face 454 opposing the first face, a substantially convex third face 456 extending to and between the first face and the second face, wherein the longitudinal axis extends through a center of the third face, a fourth face 458 opposing the third face having a substantially cross-shaped cross-section, wherein the longitudinal axis extends through a center of the fourth face, a top face 460 including anti-migration ridges 462, a bottom face 464 including anti-migration ridges 462, and a pair of holes 466 extending to and between the top face and the bottom face. The first face, the second face and the third face form a substantially U-shaped face including a substantially U-shaped protrusion 468 extending along a length of the U-shaped face and defining a graft upper ledge 470 and a graft lower ledge 472.

(89) In use, fourth sidewall 428 is pivoted open, and DLIF allograft bone graft 450 is inserted into enclosure 410 through the open doorway with the a graft upper ledge 470 engaged with the upper seat portion 440 and the graft lower ledge 472 engaged with the lower seat portion 442. Fourth sidewall 428 is then closed and fixed shut. Once assembled, DLIF implant 400 may be used to fuse adjacent vertebra according to the method illustrated in FIGS. 25 through 30 and described above, with top and bottom faces 460, 464 protruding out through U-shaped slot 438 so that anti-migration ridges 462 may directly contact adjacent the vertebrae.