METHOD OF EVALUATING CORE MUSCLES BY BIOIMPEDANCE TECHNOLOGY

Abstract

A method of evaluating core muscles by bioimpedance technology, includes the steps of: (a) measuring the resistance and reactance of a subject by a bioimpedance measuring instrument, and obtaining the subject's age, gender, and impedance factor (h2/Z), and (b) calculating the subject's core muscles by the following formula: BIA=a−b×age+c×h2/Z+d×Sex. Thereby, the present invention measures the cross-sectional area of the core muscles by means of bioimpedance analysis. The core muscles can be evaluated by the cross-sectional area of the core muscles, which can effectively reduce the measurement cost, reduce the measurement time and improve the convenience of measurement.

Claims

1. A method of evaluating core muscles by bioimpedance technology, comprising the steps of: (a) measuring the resistance and reactance of a subject by a bioimpedance measuring instrument, and obtaining the subject's age, gender, and impedance factor (h2/Z); and (b) calculating the subject's core muscles by the following formula: BIA=a−b×age+c×h2/Z+d×Sex.

2. The method of evaluating core muscles by bioimpedance technology as claimed in claim 1, wherein said core muscles are one or all of the psoas major, quadratus lumborum, erector spinae, and abdominal muscles.

3. The method of evaluating core muscles by bioimpedance technology as claimed in claim 1, wherein when said core muscles are the abdominal muscles, the formula of said core muscles is AM.sub.BIA=CM.sub.BIA−PM.sub.BIA−QM.sub.BIA−ES.sub.BIA.

4. The method of evaluating core muscles by bioimpedance technology as claimed in claim 1, wherein the a-d in the calculation formula are the regression coefficients in the regression analysis.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0010] FIG. 1 is a block diagram of a preferred embodiment of the present invention.

[0011] FIGS. 2A-2F are schematic diagrams of measurement modes of a preferred embodiment of the present invention.

[0012] FIG. 3A is a schematic diagram of the abdomen and lean muscle cross-sectional area at the L3-L4 lumbar vertebra height of a preferred embodiment of the present invention.

[0013] FIG. 3B is a computed tomography image of the abdomen and lean muscle cross-sectional area at the L3-L4 lumbar vertebra height of a preferred embodiment of the present invention.

DETAILED DESCRIPTION OF THE INVENTION

[0014] In order to explain the technical features of the present invention in detail, the following is a preferred embodiment, and the descriptions are as follows in conjunction with FIGS. 1-3. The method of evaluating core muscles by bioimpedance technology 10, mainly comprises the following steps:

[0015] Step (a): Measure the resistance and reactance of a subject by a bioimpedance measuring instrument, and obtain the subject's age, gender, and impedance factor (h2/Z). The bioimpedance measuring instrument is a commonly used instrument in the field of bioimpedance technology, so it is not shown in the drawings. In this preferred embodiment, the bioimpedance measuring instrument is an example of a standing eight-pole plate bioimpedance measuring technology.

[0016] Step (b): Calculate the subject's core muscles by the following formula: CM BIA=a−b×age+c×h2/Z+d×Sex (r.sup.2=0.910, SEE=13.42 cm.sup.2, n=286, p<0.001). In this preferred embodiment, the core muscles comprise psoas major, quadratus muscle (QM), erector spinae (ES), abdominal muscles (AM). The a-d in the calculation formula are the regression coefficients in the regression analysis.

[0017] The measurement methods of the present invention can be divided into multiple types, as shown in FIGS. 2A-2F. The left side of the diagram represents the subject's right side, and the right side represents the subject's left side. In the drawings, the current electrodes E1, E3, E5 and E7 of the bioimpedance measuring instrument are represented by hollow circles, and the sensing electrodes E2, E4, E6 and E8 of the bioimpedance measuring instrument are indicated by solid circles.

[0018] As shown in FIG. 2A, when the measurement circuit is switched to the current electrodes E1, E5 and the sensing electrodes E2, E6, the impedance value of the right body can be measured.

[0019] As shown in FIG. 2B, when the measurement circuit is switched to the current electrodes E1, E3 and the sensing electrodes E2, E6, the impedance value of the right upper limb can be measured.

[0020] As shown in FIG. 2C, when the measurement circuit is switched to the current electrodes E1, E5, and the sensing electrodes E6, E8, the impedance value of the right lower limb can be measured.

[0021] As shown in FIG. 2D, when the measurement circuit switches to the current electrodes E1, E6, and the sensing electrodes E4, E8, the torso impedance value can be measured.

[0022] As shown in FIG. 2E, when the measurement circuit switches to the current electrodes E1 and E3, and the sensing electrodes E4 and E8, the impedance value of the left upper limb can be measured.

[0023] As shown in FIG. 2F, when the measurement circuit is switched to the current electrodes E3, E7, and the sensing electrodes E6, E8, the impedance value of the left lower limb can be measured.

[0024] In other preferred embodiments, this core muscles can also be one of psoas major, quadratus lumborum, erector spinae or abdominal muscles, and its calculation formula is:

PM.sub.BIA=a−b×age+c×h2/Z+d×Sex(r.sup.2=0.919,SEE=3.31 cm.sup.2,n=286,p<0.001).

QM.sub.BIA=a−b×age+c×h2/Z+d×Sex(r.sup.2=0.920,SEE=5.07 cm.sup.2,n=286,p<0.001).

ES.sub.BIA=a−b×age+c×h2/Z+d×Sex(r.sup.2=0.934,SEE=13.07 cm.sup.2,n=286,p<0.001).

AM.sub.BIA=CM.sub.BIA−PM.sub.BIA−QM.sub.BIA−ES.sub.BIA.

[0025] CT Scanning

[0026] In this preferred embodiment, the cross-sectional area of the core muscles measured by a computed tomography scanner is used as the estimation target of the present invention. The method of the present invention utilizes variables such as body parameter measurement and bioimpedance measurement of the subject measured by the bioimpedance measuring instrument as predictive variables to establish and verify the estimation model of the cross-sectional area of the core muscles. In other preferred embodiments, the cross-sectional area of the core muscles measured by magnetic resonance imaging can also be used as the estimation target of the present invention.

[0027] In this preferred embodiment, a 64-slice computed tomography scan (Somatom Sensation 64 CT system, Siemens Corp., Germany) is performed on the abdomen of each subject, and the data is analyzed using Syngo CT2005A software. Each subject measured the abdominal segment of 2-5 lumbar vertebrae with a computed tomography scanner, but not limited to this.

[0028] Image Analysis

[0029] As shown in FIGS. 3A and 3B, in this preferred embodiment, a fixed image analysis program is used to calculate the abdominal and lean muscle cross section area (CSA) of each subject's L3-L4 lumbar vertebrae heights (in this preferred embodiment, only one computed tomography image is taken for illustration). Image analysts applied Slice-O-Matic version 4.3 software (Tomovision) to circle lean tissue and calculate the circled area. The cross-sectional area of the psoas major and the abdomen is manually divided at the waist L3-L4. In this preferred embodiment, the representative value of the cross-sectional area of the core muscles is the sum of the cross-sectional areas of the psoas major, quadratus lumborum, erector spinae or abdominal muscles. Since the psoas major has a high correlation with height, the values of the psoas major and height are expressed as CSA (cm.sup.2) and CSA/height.sup.2 (mm.sup.2/m.sup.2), respectively.

[0030] Statistical Analysis

[0031] In this preferred embodiment, as shown in Table 1, the descriptive data are represented by the mean and standard deviation, and their ranges are displayed.

[0032] The Student's t-test was used to compare the distribution types, and the Kolmogorov-Smirnov test was used to test the normal distribution of the data. All statistical analyses were performed using SPSS Ver.20 (Statistical Package for the Social Sciences, IBM SPSS statistics for Windows, Armonk, NY: IBM Corp), and the significance level was set at p<0.05 (two-tailed). Spearman correlation coefficient analysis was used to describe the correlation between variables, and stepwise regression analysis was used to analyze the relationship between gender, age, impedance factor and the core muscles, psoas, abdominal muscles, quadratus lumborum, erector spinae and area.

TABLE-US-00001 TABLE 1 Female (n = 146) Male ( n = 140) Items mean ± SD Range mean ± SD Range P Age (years) 32.1 ± 16.5 18.5-74.8 33.8 ± 14.4 18.5-77.0 >0.05 Height (cm) 160.3 ± 6.4  145.0-178.0 170.8 ± 5.9  151.5-186.0 <0.01 Weight (kg) 59.7 ± 10.9  42.0-105.0 73.9 ± 12.9  47.0-120.0 <0.001 BMI (kg/m.sup.2) 23.2 ± 4.1  16.2-38.0 25.3 ± 4.0  18.2-39.9 <0.01 Waist (cm) 81.6 ± 11.2  63.0-122.0 83.3 ± 10.7  64.0-122.0 <0.05 Hip (cm) 98.8 ± 9.8   81.0-129.0 98.9 ± 7.4   80.0-122.0 >0.05 WHR 0.83 ± 0.06 0.71-1.08 0.84 ± 0.07 0.72-1.03 <0.05 Bioimpedance Z (Ω) 658.5 ± 89.4  421.7-892.3 515.3 ± 62.8  372.0-668.0 <0.01 CT CM.sub.CT (cm.sup.2) 121.6 ± 28.8   53.6-209.6 217.6 ± 44.8  112.0-350.4 <0.01 ACSA.sub.CT (cm.sup.2) 450.7 ± 120.2 293.2 -988.9  499.0 ± 131.8  309.7-1026.4 <0.01

[0033] where, mean±SD (Standard Deviation) is the mean value, and the standard deviation; WHR is waist-hip ratio; BMI is the body mass index; CM is the core muscles; ACSA is the abdominal cross-sectional area.

[0034] Thereby, a method of evaluating core muscles by bioimpedance technology 10 provided by the present invention can use the bioimpedance value measured by the bioimpedance measuring instrument without the need for computed tomography or magnetic resonance imaging, and estimate the cross-sectional area of the subject's core muscles by the calculation formula, which is used as the basis for evaluating the subject's core muscles. Compared with computed tomography or magnetic resonance imaging, it can effectively reduce the measurement cost, reduce the measurement time, and improve the convenience of measurement.

[0035] The above-mentioned preferred embodiments are intended to help understand the principles and methods of the present invention, and the present invention is not limited to the above-mentioned preferred embodiments. Any combination and modification within the spirit and principle of the present invention shall fall within the protection scope of the present invention.