NEW FAST DISSOLVABLE TABLETS
20230292795 · 2023-09-21
Inventors
- Zhenbo MA (Kaiseraugst, CH)
- Conroy Clive SALMON (Kaiseraugst, CH)
- Paulo Henrique SANTOS (Kaiseraugst, CH)
Cpc classification
A23L33/125
HUMAN NECESSITIES
A61K9/2018
HUMAN NECESSITIES
A61K9/2059
HUMAN NECESSITIES
A61K31/455
HUMAN NECESSITIES
A61K9/2054
HUMAN NECESSITIES
A61K9/2027
HUMAN NECESSITIES
International classification
A23L33/125
HUMAN NECESSITIES
Abstract
The present invention relates to a new fast dissolvable tablet comprising physiologically active ingredients, which dissolves or can be dispersed in water (or water based liquids) fast.
Claims
1. A fast dissolvable-effervescent beverage tablet, which comprises (a) 1-40 weight-% (wt-%), based on the total weight of the fast dissolvable tablet, of at least one active ingredient, and (b) 20-95 wt-%, based on the total weight of the fast dissolvable tablet, of at least one diluent, and (c) 2-50 wt-%, based on the total weight of the fast dissolvable tablet, of at least one disintegrant, and wherein the content of any carbonate is below 1 wt-%, based on the total weight of the fast dissolvable tablet.
2. Tablet according to claim 1, wherein the tablet has a disc-like shape.
3. Tablet according to claim 1 comprising 5-30 wt-%, based on the total weight of the fast dissolvable tablet, of at least one active ingredient.
4. Tablet according to claim 1, wherein the at least active ingredient is chosen from the group consisting of vitamins, prebiotics, probiotics, carotenoids, minerals and any other dietary ingredient.
5. Tablet according to claim 1 comprising 25-90 wt-%, based on the total weight of the fast dissolvable tablet, of at least one diluent.
6. Tablet according to claim 1, wherein the least one diluent is chosen from the group consisting of sugar alcohols (such as mannitol, sorbitol and xylitol) and disaccharides (such as sucrose and lactose).
7. Tablet according to claim 1 comprising 10-45 wt-%, based on the total weight of the fast dissolvable tablet, of at least one disintegrant.
8. Tablet according to claim 1, wherein the at least one disintegrant is chosen from the group consisting of starches, crospovidone (cross linked polyvinyl N-pyrrolidone), co-processed sugar alcohol with starch and sodium starch glycolate.
9. Tablet according to claim 1, wherein the tablet comprises at least one auxiliary agent chosen from the group consisting of, flavours, colours, fillers, lubricants and sweetener.
10. Tablet according to claim 1, wherein the carbonate content is below 0.5 wt-%, based on the total weight of the tablet.
11. Tablet according to claim 1, wherein the tablet which is essentially free of any carbonate.
12. Tablet according to claim 1, wherein the tablet has a hardness of about 5 to 20 kp.
Description
EXAMPLES
Example 1
[0098] A tablet of the following composition (table 1) has been produced:
TABLE-US-00001 TABLE 1 Ingredient mg/tablet % w/w Niacinamide FCC 23.84 0.68 Calcium Pantothenate 25.93 0.74 Pyridoxine Hydrochloride 2.87 0.08 Maltodextrin 7.36 0.21 VC Ascorbic Acid regular 99.00 2.83 Potassium Citrate 204.25 5.84 Dry Vitamin E 50% CWS/S 79.02 2.26 Beta-Carotene 20% S 10.00 0.29 Citric Acid 93.00 2.66 Malic Acid 28.00 0.80 Orange flavor 80.00 2.29 Reb M 80.00 2.29 Pearlitol Flash (co-processed Mannitol with starch) 1164.52 33.27 Pearitol 200 SD (Mannitol) 1542.21 44.06 PEG 6000 60.00 1.71
[0099] The tablet with the composition of table 1 has been produced by the following procedure: [0100] 1. Sieve all ingredients through a 20 mesh screen. [0101] 2. Mix all ingredients except the lubricant in a V shaped blender for 10 mins. [0102] 3. Add sieved lubricant into step 2 and mix for 5 mins. [0103] 4. Produce tablets on a “D” type rotary press equipped with 0.875″ flat faced and bevel edged toolings.
[0104] Compression force 6000 Lbs, Press speed: 55 rpm, Tablet hardness ˜7 kp
[0105] This tablet has been dropped in about 236 ml (8 oz) of water and was shaken gently. The tablet was dissolved rapidly and completely within 2 mins.