NOVEL HYALURONIC ACID FACIAL MASK, PREPARATION METHOD THEREFOR AND USE METHOD THEREFOR

Abstract

A hyaluronic acid facial mask, a preparation method therefor and a use method therefor is provided. The facial mask includes a substrate layer, a hyaluronic acid layer and a protective paper layer sequentially arranged. The hyaluronic acid layer is made of hyaluronic acid nanofibers. The hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method. The hyaluronic acid composite includes a dispersed phase and a solvent phase. The dispersed phase includes, in terms of mass percentage content, 70-95% of hyaluronic acid. The solvent phase includes water. The preparation method includes: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form a hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer.

Claims

1. A hyaluronic acid facial mask, wherein the hyaluronic acid facial mask comprises: a substrate layer, a hyaluronic acid layer, and a protective paper layer sequentially stacked, the hyaluronic acid layer is made of hyaluronic acid nanofibers, the hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method; wherein the hyaluronic acid composite comprises a dispersed phase and a solvent phase, the dispersed phase comprises, in terms of mass percentage content, 70-95% of sodium hyaluronate and 5-30% of poly(ethylene oxide), the sodium hyaluronate has an average molecular weight of 1,000-100,000, and the poly(ethylene oxide) has an average molecular weight of 500,000-5,000,000, and the solvent phase comprises water.

2. The hyaluronic acid facial mask according to claim 1, wherein the sodium hyaluronate has an average molecular weight of 8,000-100,000.

3. The hyaluronic acid facial mask according to claim 1, wherein the poly(ethylene oxide) has an average molecular weight of 600,000-5,000,000.

4. The hyaluronic acid facial mask according to claim 1, wherein the operating parameters of the electrospinning method are: electric field voltage 20 to 200 KV, spinning distance 5 to 30 cm, spinning current 0.01 to 1 mA.

5. The hyaluronic acid facial mask according to claim 4, wherein operating parameters of the electrospinning method are: electric field voltage 36 to 70 KV, spinning distance 15 to 25 cm, and spinning current 0.23 to 0.42 mA.

6. The hyaluronic acid facial mask according to claim 1, wherein in the hyaluronic acid composite, in terms of mass percentage content, the dispersed phase accounts for 5-25%, and the solvent phase accounts for 75-95%.

7. The hyaluronic acid facial mask according to claim 1, wherein the hyaluronic acid composite is consisted of a dispersed phase and a solvent phase, the dispersed phase is consisted of sodium hyaluronate and poly(ethylene oxide), and the solvent phase is water.

8. The hyaluronic acid facial mask according to claim 1, wherein the substrate layer is a nylon-based substrate layer.

9. The hyaluronic acid facial mask according to claim 8, wherein the nylon-based substrate layer is a nylon-based mesh substrate layer with a hollow structure.

10. The hyaluronic acid facial mask according to claim 1, wherein the hyaluronic acid nanofibers have an average diameter of 50 to 500 nm.

11. The hyaluronic acid facial mask according to claim 1, wherein the hyaluronic acid layer has a thickness of 0.005-0.1 mm.

12. The hyaluronic acid facial mask according to claim 1, wherein the hyaluronic acid layer has a thickness of 0.003-0.009 mm.

13. The hyaluronic acid facial mask according to claim 1, wherein a thickness of the hyaluronic acid layer, a thickness of the substrate layer, and a thickness of the protective paper layer is 0.8-16:1:1.5-3.

14. The hyaluronic acid facial mask according to claim 1, wherein a thickness of the hyaluronic acid layer, a thickness of the substrate layer, and a thickness of the protective paper layer is 1.2-8.5:1:1.5-1.8.

15. A preparation method for a hyaluronic acid facial mask according to claim 1, wherein the preparation method comprises: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form the hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer.

16. A use method for a hyaluronic acid facial mask according to claim 1, wherein the method further comprising: during use, applying water to a part to be applied, and then directly attaching the hyaluronic acid layer of the hyaluronic acid facial mask from which the protective paper layer has been removed to the part to be applied, wherein the part to be applied comprises the face.

17. A use method for a hyaluronic acid facial mask according to claim 16, wherein the method further comprising: after attaching the hyaluronic acid layer of the hyaluronic acid facial mask to the part to be applied, applying water at least once to the part to be applied with the hyaluronic acid layer.

18. A hyaluronic acid facial mask according to claim 11, wherein the hyaluronic acid layer has a thickness of 0.03-0.09 mm.

Description

BRIEF DESCRIPTION

[0029] Some of the embodiments will be described in detail, with references to the following Figures, wherein like designations denote like members, wherein:

[0030] FIG. 1 is a scanning electron microscope image of Embodiment 1;

[0031] FIG. 2 is a scanning electron microscope image of Embodiment 2;

[0032] FIG. 3 is a scanning electron microscope image of Embodiment 3; and

[0033] FIG. 4 is a scanning electron microscope image of Embodiment 4.

DETAILED DESCRIPTION

[0034] The specific embodiments below are combined to further explain the present disclosure in detail. It should be understood that, those embodiments are to explain the basic principle, major features and advantages of the present disclosure, and the present disclosure is not limited by the scope of the following embodiments. The implementation conditions employed by the embodiments may be further adjusted according to particular requirements, and undefined implementation conditions usually are conditions in conventional experiments.

[0035] In the following embodiments, unless otherwise specified, all raw materials are basically commercially available or prepared by conventional methods in the field.

Embodiment 1

[0036] A hyaluronic acid facial mask provided by this embodiment comprises a substrate layer made of nylon-based mesh substrate layer with a hollow structure, a hyaluronic acid layer and a protective paper layer sequentially arranged, the hyaluronic acid layer is made of hyaluronic acid nanofibers, the hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method;

[0037] Wherein, the formulation of the hyaluronic acid composite and the amount of the ingredients are shown in Table 1, and the hyaluronic acid composite was prepared by mixing the dispersed phase and the solvent phase evenly.

TABLE-US-00001 TABLE 1 Embodiment 1 (Parts) Dispersed Sodium hyaluronate (with an average 4.0% phase molecular weight of 100,000, purchased from Qingdao Amochem) Poly(ethylene oxide) (with an average 1.0% molecular weight of 5,000,000, purchased from Qingdao Amochem) Solvent Water  95% phase

[0038] The preparation method was: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form the hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer; wherein, the operating parameters of the electrospinning method were: electric field voltage 36 KV, spinning distance 15 cm, and spinning current 0.23 mA; the thickness of the hyaluronic acid layer was about 0.03 mm, and the ratio of the thickness of the hyaluronic acid layer, the thickness of the substrate layer and the thickness of the protective paper layer was about 1.2:1:1.8.

Embodiment 2

[0039] A hyaluronic acid facial mask provided by this embodiment comprises a substrate layer made of nylon-based mesh substrate layer with a hollow structure, a hyaluronic acid layer and a protective paper layer sequentially arranged, the hyaluronic acid layer is made of hyaluronic acid nanofibers, the hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method;

[0040] Wherein, the formulation of the hyaluronic acid composite and the amount of the ingredients are shown in Table 2, and the hyaluronic acid composite was prepared by mixing the dispersed phase and the solvent phase evenly.

TABLE-US-00002 TABLE 2 Embodiment 2 (Parts) Dispersed Sodium hyaluronate (with an average  9% phase molecular weight of 60,000, purchased from Qingdao Amochem) Poly(ethylene oxide) (with an average 1.0%  molecular weight of 2,000,000, purchased from Qingdao Amochem) Solvent Water 90% phase

[0041] The preparation method was: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form the hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer; wherein, the operating parameters of the electrospinning method were: electric field voltage 55 KV, spinning distance 17 cm, and spinning current 0.31 mA; the thickness of the hyaluronic acid layer was about 0.05 mm, and the ratio of the thickness of the hyaluronic acid layer, the thickness of the substrate layer and the thickness of the protective paper layer was about 2.5:1:1.8.

Embodiment 3

[0042] A hyaluronic acid facial mask provided by this embodiment comprises a substrate layer made of nylon-based mesh substrate layer with a hollow structure, a hyaluronic acid layer and a protective paper layer sequentially arranged, the hyaluronic acid layer is made of hyaluronic acid nanofibers, the hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method;

[0043] Wherein, the formulation of the hyaluronic acid composite and the amount of the ingredients are shown in Table 3, and the hyaluronic acid composite was prepared by mixing the dispersed phase and the solvent phase evenly.

TABLE-US-00003 TABLE 3 Embodiment 3 (Parts) Dispersed Sodium hyaluronate (with an average 10.5% phase molecular weight of 25,000, purchased from Qingdao Amochem) Poly(ethylene oxide) (with an average  1.5% molecular weight of 1,000,000, purchased from Qingdao Amochem) Solvent Water .sup. 88% phase

[0044] The preparation method was: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form the hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer; wherein, the operating parameters of the electrospinning method were: electric field voltage 68 KV, spinning distance 25 cm, and spinning current 0.36 mA; the thickness of the hyaluronic acid layer was about 0.07 mm, and the ratio of the thickness of the hyaluronic acid layer, the thickness of the substrate layer and the thickness of the protective paper layer was about 3.1:1:1.8.

Embodiment 4

[0045] A hyaluronic acid facial mask provided by this embodiment comprises a substrate layer made of nylon-based mesh substrate layer with a hollow structure, a hyaluronic acid layer and a protective paper layer sequentially arranged, the hyaluronic acid layer is made of hyaluronic acid nanofibers, the hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method;

[0046] Wherein, the formulation of the hyaluronic acid composite and the amount of the ingredients are shown in Table 4, and the hyaluronic acid composite was prepared by mixing the dispersed phase and the solvent phase evenly.

TABLE-US-00004 TABLE 4 Embodiment 4 (Parts) Dispersed Sodium hyaluronate (with an average 21% phase molecular weight of 8,000, purchased from Qingdao Amochem) Poly(ethylene oxide) (with an average  3% molecular weight of 600,000, purchased from Qingdao Amochem) Solvent Water 76% phase

[0047] The preparation method was: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form the hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer; wherein, the operating parameters of the electrospinning method were: electric field voltage 70 KV, spinning distance 20 cm, and spinning current 0.42 mA; the thickness of the hyaluronic acid layer was about 0.09 mm, and the ratio of the thickness of the hyaluronic acid layer, the thickness of the substrate layer and the thickness of the protective paper layer was about 8.5:1:1.5.

[0048] Comparison 1

[0049] This example was basically the same as in Embodiment 1, by differing in that, only sodium hyaluronate was used as the dispersed phase, without the addition of poly(ethylene oxide).

[0050] Effectiveness Evaluation

[0051] 1. Scanning Electron Microscope

[0052] As shown in FIG. 1, the spun yarn in Embodiment 1 is uniform and dense;

[0053] As shown in FIG. 2, the spun yarn in Embodiment 2 is also uniform and dense (at a different magnification than in Embodiment 1);

[0054] As shown in FIG. 3, the spun yarn in Embodiment 3 is uniform, with no interlacing of the fiber layers;

[0055] As shown in FIG. 4, the spun yarn in Embodiment 4 is uniform and dense, with smaller diameter;

[0056] Comparison 1 cannot be spun, the liquid was squirted straight out.

[0057] 2. Yarn Surface Condition

TABLE-US-00005 Embodiment 1 The surface of the yarn layer was uniformly colored with a few micropores Embodiment 2 The surface of the yarn layer was uniform with very few micropores Embodiment 3 The surface of the yarn layer was smooth and uniformly colored Embodiment 4 The surface of the yarn layer was uniformly colored, smooth and delicate Comparison 1 Unable to spin

[0058] 3. Curling of Mask and Mesh Substrate Layer Under High Humidity Conditions

[0059] With the rainy weather in the southern part of the country, the air was very humid, on the day of the test the humidity was around 90%, while several samples were opened and laid flat on a table to observe the dissolution and curling of the mask and mesh substrate layers.

TABLE-US-00006 Embodiment 1 The white mask had no change in color and slightly curled at both chins after 30 min Embodiment 2 The white mask was translucent in color and slightly curled at both chins after 30 min Embodiment 3 The white mask had no change in color and no curling at several incisions after 30 min Embodiment 4 The white mask had no change in color and no curling at several incisions after 30 min Comparison 1 No finished product to be tested Note: Under high humidity, moisture in the air will be absorbed into the hyaluronic acid layer, showing a slightly soluble state, resulting in the color of the mask layer becoming transparent;

[0060] 4. Use of Mask

TABLE-US-00007 Effects of water Cases supplement Feelings Embodiment 1 8 The hyaluronic acid layer was well distributed, the rapid penetration and disappearance of hyaluronic acid was observed when applied to the face, and after application, the face was slightly tight, and the face tightness was improved after patting with water twice; a noticeable effect of water supplement on the face was observed after waking up in the morning. Embodiment 2 9 The hyaluronic acid layer was well distributed, the rapid penetration and disappearance of hyaluronic acid was observed when applied to the face, and after application, the face was tight, and felt sticky after patting with water, and the tight and sticky feeling disappeared after 4 patting with water. Embodiment 3 9 The hyaluronic acid layer was soft, and can be seen through the gauze, the rapid disappearance of hyaluronic acid was observed when applied to the face, the experience was good, the face was tight after application, and felt fresh and non-greasy after 4 patting with water, and the skin was not oily when wake up the next morning. Embodiment 4 10 The skin was tight after application, after removing the mesh cloth, a stickiness on the surface of the skin can be felt after patting with the hand to replenish moisture, and the skin had an obvious improvement in skin glossiness! Comparison 1 / No product experience Note: Rating: 1-10, with 1 being the worst and 10 being the best.

[0061] The embodiments described above are only for illustrating the technical concepts and features of the present disclosure, and are intended to make those skilled in the art being able to understand the present disclosure and thereby implement it, and should not be concluded to limit the protective scope of this disclosure. Any equivalent variations or modifications according to the spirit of the present disclosure should be covered by the protective scope of the present disclosure.

[0062] The endpoints and any values of the ranges disclosed herein are not limited to the precise ranges or values, and these ranges or values should be understood to include values close to these ranges or values. For ranges of value, between the end values of each range, between the end values of each range and individual point values, and between individual point values can be combined with each other to obtain one or more new ranges of value, and these ranges of value should be considered as specifically disclosed herein.

[0063] Although the present invention has been disclosed in the form of embodiments and variations thereon, it will be understood that numerous additional modifications and variations could be made thereto without departing from the scope of the invention.

[0064] For the sake of clarity, it is to be understood that the use of ‘a’ or ‘an’ throughout this application does not exclude a plurality, and ‘comprising’ does not exclude other steps or elements.