SUNSCREEN COMPOSITION WITH LOW STICKINESS

Abstract

The present invention relates to a topical preparation comprising a UV filter combination of certain microfine zinc oxide, 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and 4,4′-((6((4 (((1,1-dimethylethyl)amino)carbonyl)phenyl)-amino)-1,3,5-triazine-2,4-diyl)diimino)bis(2-ethylhexyl)benzoate (INCI: Diethylhexyl butamido triazone).

Claims

1. A topical composition, wherein the composition comprises a UV filter combination of a.) a microfine zinc oxide, wherein the microfine zinc oxide has a mean particle size D.sub.n50 as determined by Laser diffraction selected in the range from 30 to 200 nm and a surface coating selected from the group consisting of aluminum stearate, stearic acid, methicone, simethicone, triethoxycaprylylsilane and octyltrimethoxysilane, b.) 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), c.) 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and d.) 4,4′-((6((4 (((1,1-dimethylethyl)amino)carbonyl)phenyl)-amino)-1,3,5-triazine-2,4-diyl)diimino)bis(2-ethylhexyl)benzoate (INCI: Diethylhexyl butamido triazone).

2. The topical composition according to claim 1, wherein the mean particle size D.sub.n50 is selected in the range from 50 to 200 nm, preferably in the range from 75 to 150 nm, most preferably in the range from 90 to 130 nm as determined by Laser diffraction.

3. The topical composition according to claim 1, wherein the microfine zinc oxide is surface coated with triethoxycaprylylsilane.

4. The topical composition according to claim 1, wherein the amount of the microfine zinc oxide is selected in the range from 0.1 wt.-% to 20 wt.-%, preferably in the range from 0.5 wt.-% to 10 wt.-%, most preferably in the range of 5 wt.-% to 10 wt.-%, based on the total weight of the composition.

5. The topical composition according to claim 1, wherein the composition contains no 3-(4-methylbenzylidene)camphor, 2-hydroxy-4-methoxybenzophenone (INCI: Oxybenzone), and ethylhexyl 2-cyano-3,3-diphenylacrylate (INCI: Octocrylene).

6. The topical composition according to claim 1, wherein the composition is an O/W emulsion.

7. The topical composition according to claim 1, wherein the composition comprises one or more of Ceteareth-6 and Ceteareth-25 as emulsifier.

8. The topical composition according to claim 1, wherein the composition comprises one or more of dibutyl adipate, dicaprylyl carbonate and C12-C15 alkylbenzoate.

9. The topical composition according to claim 1, wherein the composition comprises one or more of ethanol, p-hydroxyacetophenone, phenoxyethanol and ethylhexylglycerin.

10. The topical composition according to claim 1, wherein the composition comprises one or more of xanthan gum, crosslinked acrylate/C10-C30 alkyl acrylate polymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer & Squalane & Polysorbate 60 and vinylpyrrolidone/hexadecene copolymer.

11. The topical composition according to claim 1, wherein the composition comprises one or more of cetyl alcohol, cetearyl alcohol, stearyl alcohol and glyceryl stearate.

12. The composition according to claim 1, wherein the composition has an SPF of at least 20.

13. Use of microfine zinc oxide to reduce the stickiness of a topical composition comprising a 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and 4,4′-((6((4 (((1,1-dimethylethyl)amino)carbonyl)phenyl)-amino)-1,3,5-triazine-2,4-diyl)diimino)bis(2-ethylhexyl)benzoate (INCI: Diethylhexyl butamido triazone).

14. Method for reducing the stickiness and/or the sand adherence on skin of a topical composition comprising 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and 4,4′-((6((4 (((1,1-dimethylethyl)amino)carbonyl)phenyl)-amino)-1,3,5-triazine-2,4-diyl)diimino)bis(2-ethylhexyl)benzoate (INCI: Diethylhexyl butamido triazone) said method encompassing the step of incorporating microfine zinc oxide into said topical composition before applying said composition to skin.

Description

EXAMPLE 1

[0108] The formulations (O/W emulsions) as outlined in table 1 have been prepared according to standard methods in the art. Then the sand repellence has been tested according to the method as outlined below: [0109] Apply 30 mg of cream on PMMA plate (2 mg/cm.sup.2) and distribute homogenously [0110] Let it dry for 15 minutes [0111] Weigh the PMMA plate [0112] Put 30 g of sand (Spielsand (Hornbach) Körnung von 0.06 bis 1 mm) on top of the PMMA plate such as that the surface is completely covered [0113] Let it dry for 15 minutes [0114] Turn the PMMA plate 180° without shaking [0115] Weigh the PMMA plate [0116] Calculate the amount of sand sticking on the plate [0117] Repeat test with 4 plates per sample

[0118] The results are outlined in Table 1

TABLE-US-00001 TABLE 1 Ref 1 Inv 1 Tradename INCI Wt.-% Cetiol ® CC Dicaprylyl carbonate 10.00 10.00 Uvasorb ® HEB Diethylhexylbutamido triazone 2.00 2.00 Finsolv ® TN C12-15 Alkyl Benzoate 8.00 8.00 PARSOL ® Shield Bis-ethylhexylphenol methoxyphenyl triazine 2.00 2.00 Dispersun DSP-OL300 Polyhydroxystearic acid 0.50 0.50 Myritol ® 318 Caprylic/Capric triglyceride 10.00 — Parsol ® ZX Zinc Oxide and triethoxycaprilylsilane — 10.00 Keltrol ® CG-T Xanthan Gum 0.20 0.20 Lanette ® O Cetearyl alcohol 1.50 1.50 Lanette ® 22 Behenyl alcohol 1.50 1.50 Euxyl ® PE 9010 Phenoxyethanol, Ethylhexylglycerin 1.00 1.00 Emulgade ® A 6 Ceteareth-6; stearyl alcohol 2.00 2.00 Eumulgin ® B 25 Ceteareth-25 2.00 2.00 Edeta BD Disodium EDTA; Aqua 0.20 0.20 PARSOL ® HS Phenylbenzimidazol sulfonic acid 2.00 2.00 Natriumhydroxid 30% Aqua; sodium hydroxide 1.00 1.00 soln. WATER DEM. Aqua Ad 100 Ad 100 Glycerin 1,23 Glycerin 3.00 3.00 (86.5%) Ph. Eur. Simulgel NS Hydroxyethyl acrylate/sodium 0.5 0.5 acryloyldimethyl Taurate copolymer; Squalane, Polysorbate 60 Remaining amount of sand on the plate [mg] 945 777 Standard deviation [mg] 70 79 % reduction (less sand) vs. Ref 1 −18% SPF 20 31

[0119] As can be retrieved from table 1, the combination according to the present invention results in a synergistic reduction of sand sticking to the plates, i.e. a synergistically improved sand repellence.

EXAMPLE 2

[0120] The formulations (O/W emulsions) as outlined in table 2 have been prepared according to standard methods in the art. Then the sand repellence has been tested according to the method as outlined below: [0121] Apply 2 mg/cm.sup.2 of cream on PMMA plate and distribute homogenously [0122] Let it dry for 15 minutes @ 40° C. [0123] Weigh the PMMA plate [0124] Put sand (Kultpfötchen 5 kg—Terrarium Sand Natur beige|Körnung 0.4-0.8 mm) into a petri dish, place the plate with cream film side on sand put a weight (500 g) on plate, wait 5 minutes [0125] Take the plate out and turn the PMMA plate 180° without shaking [0126] Weigh the PMMA plate [0127] Calculate the amount of sand sticking on the plate [0128] Repeat test with 4 plates per sample

[0129] The results are outlined in Table 2

TABLE-US-00002 #8215 #8213 #821 Tradename INCI Wt.-% Cetiol ® CC Dicaprylyl carbonate 10.00 10.00 10.00 Uvasorb ® HEB Diethylhexylbutamido triazone 2.00 2.00 2.00 Finsolv ® TN C12-15 Alkyl Benzoate 8.00 8.00 8.00 PARSOL ® Bis-ethylhexylphenol 2.00 2.00 2.00 Shield methoxyphenyl triazine Dispersun DSP- Polyhydroxystearic acid 0.50 0.50 0.50 OL300 ZnO-C-DS4 Zinc oxide and dimethicone — 10.00 — Parsol ® ZX Zinc Oxide and — — 10.00 triethoxycaprylylsilane Keltrol ® CG-T Xanthan Gum 0.20 0.20 0.20 Lanette ® O Cetearyl alcohol 1.50 1.50 1.50 Lanette ® 22 Behenyl alcohol 1.50 1.50 1.50 Euxyl ® PE 9010 Phenoxyethanol, Ethylhexylglycerin 1.00 1.00 1.00 Emulgade ® A 6 Ceteareth-6; stearyl alcohol 2.00 2.00 2.00 Eumulgin ® B 25 Ceteareth-25 2.00 2.00 2.00 Edeta BD Disodium EDTA; Aqua 0.20 0.20 0.20 PARSOL ® HS Phenylbenzimidazol sulfonic acid 2.00 2.00 2.00 Natriumhydroxid Aqua; sodium hydroxide 1.00 1.00 1.00 30% soln WATER DEM. Aqua Ad 100 Ad 100 Ad 100 Glycerin 1,23 Glycerin 3.00 3.00 3.00 (86.5%) Ph. Eur. Simulgel NS Hydroxyethyl acrylate/sodium 0.5 0.5 0.5 acryloyldimethyl Taurate copolymer; Squalane, Polysorbate 60 Remaining amount of sand on the plate [mg] 768 682 524 Standard deviation [mg] 71 53 75 % reduction (less sand) vs. 8215 −11% −32% % reduction (less sand) vs. 8213 −23%

[0130] As can be retrieved from table 2, the combination according to the present invention results in a reduction of sand sticking to the plates, while the use triethoxycaprylylsilane coated zinc oxide is advantageous over the use of dimethicone coated zinc oxide.