Conduction-cooled radiofrequency coil subsystem and magnetic resonance imaging magnet system having the same
11543476 · 2023-01-03
Assignee
Inventors
Cpc classification
G01R33/3403
PHYSICS
G01R33/34046
PHYSICS
G01R33/3621
PHYSICS
International classification
Abstract
A conduction-cooled radiofrequency coil subsystem of MRI system with high signal-to-noise ratio imaging capability at low field and/or ultra-low field. The conduction-cooled RF coil subsystem includes a radiofrequency (RF) coil module having at least one RF instrumentation; a cryocooler; and a thermal conduction line thermally connected between the cryocooler and the RF instrumentation. The RF coil module further includes a housing defining a thermally insulated vessel for accommodating the RF instrumentation. The thermal conduction line is thermally coupled to the cryocooler which is located outside the housing of the RF coil module and the RF instrumentation in the thermally insulated vessel to conduction cool the RF instrumentation. The at least one RF instrumentation includes one or more of an RF transceiver coil, an RF receiver coil, an RF preamplifier and an RF electronics module.
Claims
1. A conduction-cooled radiofrequency coil subsystem of MRI system with high signal-to-noise ratio imaging capability at low field and/or ultra-low field, the conduction-cooled radiofrequency coil subsystem comprising: a radiofrequency (RF) coil module, comprising: a housing defining a thermally insulated vessel, and at least one RF instrumentation accommodated in the thermally insulated vessel of the housing, wherein the at least one RF instrumentation comprises one or more of an RF transceiver coil, an RF receiver coil, an RF preamplifier and an RF electronics module; a cryocooler located outside the housing of the RF coil module and configured for conduction cooling the RF instrumentation; and a thermal conduction element thermally connected between the cryocooler and the RF instrumentation in the thermally insulated vessel to conduction cool the RF instrumentation; wherein the conduction-cooled radiofrequency coil subsystem further comprises a casing for accommodating the cryocooler, and the casing is arranged outside and separated apart from the RF coil module, and wherein the thermal conduction element includes a tubular outer insulating layer defining a lumen therein, and the at least one RF instrumentation comprises a wire extending into the thermal conduction element and running in the lumen.
2. The conduction-cooled radiofrequency coil subsystem according to claim 1, wherein the cryocooler is a one-stage cryocooler and is configured to cool the RF instrumentation to a first temperature T1.
3. The conduction-cooled radiofrequency coil subsystem according to claim 2, wherein the first temperature T1 is ranged from 40 to 70 K.
4. The conduction-cooled radiofrequency coil subsystem according to claim 1, wherein the cryocooler comprises at least a first stage part and a second stage part, wherein the first stage part is configured to cool the RF instrumentation to a first temperature T1, the second stage part is configured to cool the RF instrumentation to a second temperature T2 which is lower than the first temperature T1.
5. The conduction-cooled radiofrequency coil subsystem according to claim 4, wherein the first temperature T1 is ranged from 40 to 70 K, and the second temperature T2 is ranged from 2 to 40 K.
6. The conduction-cooled radiofrequency coil subsystem according to claim 1, further comprising a heat transfer member arranged within the thermal conduction element between the cryocooler and the RF instrumentation, wherein the heat transfer member is heat-conducting.
7. The conduction-cooled radiofrequency coil subsystem according to claim 6, wherein the material of the heat transfer member comprises one or more of the following: copper, aluminum, pyrolytic graphite, beryllium oxide, sapphire, diamond, and respective composites thereof.
8. The conduction-cooled radiofrequency coil subsystem according to claim 6, further comprising a cooling substrate arranged between the heat transfer member and the RF instrumentation within the thermally insulated vessel for conductive cooling the RF instrumentation, wherein the cooling substrate is heat-conducting but is substantially electrically non-conducting.
9. The conduction-cooled radiofrequency coil subsystem according to claim 8, wherein the material of the cooling substrate comprises one or more of the following: thermal paste, pyrolytic graphite, beryllium oxide, sapphire, diamond, composites thereof, and any combination thereof.
10. The conduction-cooled radiofrequency coil subsystem according to claim 6, further comprising a heat sink located within the thermally insulated vessel and being in contact with electronic elements of the RF preamplifier or the RF electronics module, and wherein the heat transfer member is arranged between the cryocooler and the heat sink, and wherein the heat sink is made of material with high thermal conductivity and low or none electricity conductivity.
11. The conduction-cooled radiofrequency coil subsystem according to claim 10, wherein a material of the heat sink comprises one or more of the following: copper, aluminum, pyrolytic graphite, beryllium oxide, sapphire, diamond, and respective composites thereof.
12. The conduction-cooled radiofrequency coil subsystem according to claim 1, further comprising at least one connector coupled to the thermal conduction element, and the connector is flexible or rigid, wherein the thermal conduction element is detachably connected to the RF coil module and/or the cryocooler by the at least one connector.
13. The conduction-cooled radiofrequency coil subsystem according to claim 12, wherein one of the at least one connector is connected between the cryocooler and the thermal conduction element, and/or one of the at least one connector is connected between the thermal conduction element and the thermally insulated vessel.
14. The conduction-cooled radiofrequency coil subsystem according to claim 1, wherein the MRI system has a field strength for imaging ranged from 0.01 to 0.1T′.
15. The conduction-cooled radiofrequency coil subsystem according to claim 1, the at least one RF instrumentation comprises an RF electronics module located outside of the RF coil module.
16. The conduction-cooled radiofrequency coil subsystem according to claim 15, wherein the RF electronics module is arranged outside the casing.
17. The conduction-cooled radiofrequency coil subsystem according to claim 15, wherein the RF electronics module is arranged within the casing, and wherein the RF electronic module is thermally connected to the cryocooler.
18. The conduction-cooled radiofrequency coil subsystem according to claim 1, wherein the RF coil module is a head-only RF coil module, or a body RF coil module.
19. An MRI magnet system with high signal-to-noise ratio imaging capability at low field and/or ultra-low field, comprising: a main magnet for generating main magnetic field, the main magnet being a permanent magnet, a resistive magnet, a superconducting magnet, or any combination thereof; and a conduction-cooled radiofrequency coil subsystem; comprising: a radiofrequency (RF) coil module comprising a housing defining a thermally insulated vessel; and at least one RF instrumentation accommodated in the thermally insulated vessel of the housing, wherein the at least one RF instrumentation comprises one or more of an RF transceiver coil, an RF receiver coil, an RF preamplifier and an RF electronics module; a cryocooler located outside the housing of the RF coil module and configured for conduction cooling the RF instrumentation; and a thermal conduction element thermally connected between the cryocooler and the RF instrumentation in the thermally insulated vessel to conduction cool the RF instrumentation; wherein the conduction-cooled radiofrequency coil subsystem further comprises a casing for accommodating the cryocooler, and the casing is arranged outside and separated apart from the RF coil module, and wherein the thermal conduction element includes a tubular outer insulating layer defining a lumen therein, and the at least one RF instrumentation comprises a wire extending into the thermal conduction element and running in the lumen.
20. The URI magnet system according to claim 19, further comprising another different cryocooler configured for cooling the superconducting magnet when presence.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
DESCRIPTION OF THE EMBODIMENTS
(15) To make the technical solutions and advantages of the present disclosure more apparent, the present disclosure will be described in detail below with reference to accompanying drawings and specific embodiments. It is to be understood that the drawings are merely provided for reference and illustration and are not intended to limit the present invention. The dimensions shown in the drawings are only for the sake of clearly describing and do not limit the proportional relationship there among. In addition, the relative terms such as “first” and “second” are only used to distinguish elements, components or stages with the same name, and do not indicate or imply any such actual relationship or order between these elements, components or stages.
(16) It should be noted that, in the present application, the term “low field” refers to a field strength for imaging ranged from 0.1 to 0.5T, the term “ultra-low field” refers to a field strength for imaging ranged from 0.01 to 0.1T, whilst the term “high field” refers to a field strength for imaging ranged from 1.5 to 3.0T.
(17) The issue of signal-to-noise ratio (SNR) performance is particularly critical for low field and ultra-low field magnetic resonance imaging (MRI) systems, whereby SNR is extremely low compared to conventional high-field MRI systems given the approximately linear relationship between SNR and field strength. A typical strategy utilized to improve SNR performance in high-field MRI systems by increasing magnetic field strength is therefore not possible in low and ultra-low field systems.
(18) In addition to the main magnetic field of the MRI system generated by main magnets such as permanent magnets, resistive magnets or superconducting magnets, MRI radiofrequency (RF) instrumentations, such as RF transceiver coils or RF receiver coils, are essential components for every MRI examination, as they are responsible for the excitation and the reception of the MR signal to generate an image. Therefore, improvements made to the RF instrumentations servers as an important avenue to alleviate low SNR performance of low and ultra-low field MRI systems.
(19) SNR for RF instrumentations are primarily affected by the performance of RF receiver coil and RF electronics such as the preamplifiers. A number of considerations are needed in the design of RF instrumentations at low and ultra-low field MRI systems to improve the SNR performance, which are summarized with equations (1) to (4) below. In this disclosure, the low SNR issue of low field and ultra-low field MRI systems has been resolved by improving the performance of RF receiver coil and RF electronics such as the preamplifiers.
(20)
(21) where:
(22) B.sub.0 denotes magnitude of main magnetic field strength
(23) B.sub.1 denotes magnitude of magnetic field generated by RF transmitter perpendicular to B.sub.0
(24) K denotes Boltzmann constant
(25) T.sub.coil denotes RF coil temperature
(26) Δf denotes receiver bandwidth of the imaging scan
(27) R.sub.eff denotes effective resistive loss
(28) R.sub.coil denotes resistive losses of the RF coil
(29) R.sub.electronics denotes resistive losses of the electronic elements of the RF preamplifiers
(30) R.sub.sample denotes resistive losses of the sample
(31) α denotes temperature coefficient of resistance for RF coil material
(32) ω denotes resonant frequency of protons at a particular main magnetic field strength
(33) In Equation (1), the SNR of RF instrumentations is dependent upon B.sub.1, which is related to RF transmitter coil, and noise, which is related to RF receiver coil and RF electronics such as the preamplifiers. The noise term is primarily dominated by the effective temperature (T.sub.eff) and the effective resistive loss (R.sub.eff) of the RF receiver coil (R.sub.coil), electronic elements of the RF preamplifiers (R.sub.electronics) and the sample that is being imaged by the MRI system (R.sub.sample), as in Equation (2). Each of these three resistive losses are affected by a combination of numerous factors such as temperature (T.sub.1), resonant frequency of protons (ω), and/or field strength (B.sub.0) of the MRI system. R.sub.coil is dominated by temperature of the RF coil (T.sub.1), whereby a lower temperature is favored to reduce the resistance and subsequently the resistive losses (Equation 3). Similarly, R.sub.electronics follows the characteristics of R.sub.coil, whereby a lower temperature is favored for better RF preamplifier performance to enable higher SNR performance when amplifying signals received by the RF receiver coils. In addition to temperature, R.sub.coil is also affected by w which scales approximately linearly with B.sub.0. At low field and ultra-low field, ω is two orders of magnitude smaller when compared to conventional high field clinical scanners. R.sub.sample is dominated by ω and is negligible at low field and ultra-low field MRI systems.
(34) Hence, it can be observed from the Equations above that decreasing the effective temperature of the RF instrumentations will significantly improve the SNR performance of low field and ultra-low field MRI systems by directly reducing the noise factor of the RF transceiver or receiver coils and RF preamplifiers. In the present disclosure, a new RF coil subsystem is provided for increasing SNR performance of low field and ultra-low field MRI systems.
(35) Referring to
(36) The RF coil module 10 includes a housing 12, and RF instrumentations received in the housing 12. The RF instrumentations may include, for example, RF transceiver coils or RF receiver coils 14, and preamplifiers 16. The housing 12 is of a double-wall structure which includes an outer wall 122 and an inner wall 124 with a thermally insulated vessel 126 defined between the outer wall 122 and the inner wall 124. The thermally insulated vessel 126 is thermally insulated from the outside environment, and preferably the thermally insulated vessel is vacuum. The RF instrumentations including the RF transceiver coils or RF receiver coils 14, and the preamplifiers 16 are received in the thermally insulated vessel 126 enclosed and sealed by the outer wall 122 and the inner wall 124. The RF coil module 10 may comprise single-channel or multi-channel array RF transceiver coils or receiver coils.
(37) Referring also to
(38) The cryocooler 20 is at least a one-stage cryocooler, and is configured to thermally coupled to the thermally insulated vessel 126 and in turn to the RF instrumentations to conduction cool the RF instrumentations, i.e., the RF transceiver coils or receiver coils 14 and the RF preamplifiers 16 in this embodiment. In some embodiments, the cryocooler 20 is a one-stage cryocooler, and is configured to conduction cool the RF instrumentations to 40 to 70 Kelvin (K). In other embodiments, for example as shown in
(39) In this embodiment, the cryocooler 20 is received or enclosed in a casing 50. The casing 50 may be arranged separated apart from the RF coil module 10. The RF electronics module 40 is located outside both the housing 12 of the RF coil module 10 and the casing 50 of the cryocooler 20.
(40) The thermal conduction line 30 thermally connects the RF instrumentations to the cryocooler 20. Specifically, the thermal conduction line 30 includes a tubular outer insulating layer 31 defining a lumen therein. Preferably, the thermal conduction line 30 is vacuum and thus is thermally insulated from outside environment. It should be noted that vacuum condition is preferred to prevent thermal convection and conduction. For this purpose, it is also possible to use silver layer or the like to avoid the thermal radiation issue. In some embodiments, the thermal conduction line 30 may be flexible. Alternatively, the thermal conduction line 30 may be rigid in other embodiments. Wires 142 of the RF transceiver or receiver coils 14 may extend into the thermal conduction line 30 and run in the lumen.
(41) The wires 142 of the coils 142 extend into the casing 50 and further extend to and are connected with the RF electronics module 40.
(42) Preferably, the subsystem 100 includes a heat transfer member 32 thermally connected between the cryocooler 20 and the RF instrumentations for transferring heat from the RF instrumentations to the cryocooler 20, i.e., from the RF transceiver coils or receiver coils 14 and the RF preamplifiers to the cryocooler 20, to transfer heat from the RF instrumentations to the cryocooler 20. Specifically, one end of the heat transfer member 32 is in thermal contact with the RF instrumentations and the other end of the heat transfer member 32 is thermally connected to the cryocooler 20. In this embodiment, at least a portion of the heat transfer member 32 is housed in and runs along the thermal conduction line 30.
(43) The heat transfer member 32 is heat-conducting. For example, the heat transfer member 32 may be made of copper, aluminum, pyrolytic graphite, beryllium oxide, sapphire, diamond, their respective composites or any combination of the above materials, which have excellent heat conductive properties. Preferably, the heat transfer member is substantially electrically non-conducting or low conductive at areas or positions that are located adjacent to the electronics to avoid interference due to electrical coupling. Therefore, pyrolytic graphite, beryllium oxide, sapphire, diamond, their respective composites or any combination of the above materials would be preferred at least for such areas or portions of the heat transfer member. In case that the heat transfer member 32 includes sapphire or diamond, sapphire or diamond in the form of sheets of bars are preferred.
(44) In particular, the thermal conduction line 30 may be detachably connected to the RF coil module 10 and/or the cryocooler 20 by connectors 60.
(45) In some embodiments, a cooling substrate may be provided between the RF instrumentation and the heat transfer member for conductive cooling of the RF instrumentation within the thermally insulated vessel.
(46) For example, as shown in
(47) In some embodiments, a heatsink 80 may further be provided between the RF instrumentation and the heat transfer member 32, and is in thermal contact with the RF instrumentation for conducting heat therefrom. For example, as shown in
(48)
(49) As shown in
(50)
(51) As shown in
(52)
(53) Referring to
(54) It should be noted that although the present disclosure has been illustrated and described in detail by way of examples in the drawings and in the above descriptions, these illustrations and descriptions are merely exemplary and not intended to make any limitation. That is, the embodiments shown and described are provided by way of example only and do not intended to limit the scope of protection of the present invention in any way. It is to be understood that any features described in any embodiment can be used in combination with any other embodiment. Those of ordinary skill in the art should understand that modifications or equivalent substitutions can be made by those skilled in the art to the above embodiments, and all technical solutions and improvements that do not depart from the spirit and scope of the present invention fall within the scope of protection of the present invention.