Bandage with UV disinfectant and microneedles for antimicrobial delivery and fluid absorption from a wound

Abstract

A bandage is formed of a film layer, an adhesive applied to the film layer, and an absorbent layer connected to the film layer. The absorbent layer comprises a compressed fabric soaked in a fluid. A permeable membrane is disposed over the absorbent layer and creates an electrical charge when fluid from the absorbent layer passes through the membrane. The electricity generated by the osmosis flows to a plurality of light emitting diodes that are connected to the membrane through a battery. The LEDs emit UV light to disinfect a wound when a bandage is applied to the wound.

Claims

1. A bandage comprising: a film layer having a top surface and a bottom surface; an adhesive applied to the bottom surface; and an absorbent layer connected to the bottom surface, the absorbent layer being impregnated with a fluid, a permeable membrane connected to the absorbent layer; a power storage device connected to the permeable membrane; and a plurality of light-emitting diodes connected to the power storage device and configured to emit light in the ultraviolet spectrum; wherein the power storage device is configured to store electricity generated by osmosis of the fluid from the absorbent layer into a wound when the bandage is applied to the wound, and wherein the power storage device is configured to supply the electrical power to the light-emitting diodes such that the light-emitting diodes emit ultraviolet light onto the wound when the bandage is applied to the wound.

2. The bandage according to claim 1, further comprising a photovoltaic cell arranged on the top surface of the film layer and being electrically connected to the power storage device, wherein the photovoltaic cell is configured to convert solar energy to electric power and supply the electrical power to the power storage device to supplement the electrical power generated by the osmosis of the fluid from the absorbent layer into the wound.

3. The bandage according to claim 1, further comprising a plurality of microneedles disposed within the absorbent layer, each one of the plurality of microneedles having an end that extends through the absorbent layer and the permeable membrane and is configured to penetrate the wound when the bandage is applied over the wound; an antimicrobial agent disposed within the bandage and in communication with said plurality of microneedles, so that upon application of the bandage to the wound, the antimicrobial agent is transported though said plurality of microneedles to the wound.

4. The bandage according to claim 3, further comprising a cover layer over the absorbent layer and ends of the microneedles, said cover layer preventing the antimicrobial agent from exiting the microneedles, and wherein removal of the cover layer allows the antimicrobial agent to flow through the fraction of microneedles and into the wound.

5. The bandage according to claim 4, wherein the antimicrobial agent is disposed inside the microneedles prior to removal of the cover layer.

6. The bandage according to claim 4, wherein the antimicrobial agent is microencapsulated.

7. The bandage according to claim 6, wherein the microencapsulation is configured so that the antimicrobial agent is released in a time-delayed manner.

8. The bandage according to claim 1, wherein the film layer extends in at least two directions beyond edges of the absorbent layer.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

(1) Other objects and features of the present invention will become apparent from the following detailed description considered in connection with the accompanying drawings. It is to be understood, however, that the drawings are designed as an illustration only and not as a definition of the limits of the invention.

(2) In the drawings, wherein similar reference characters denote similar elements throughout the several views:

(3) FIG. 1 shows a cross-sectional view of the bandage according to the invention prior to use;

(4) FIG. 2 shows another embodiment of the bandage;

(5) FIG. 3 shows a top view of the bandage;

(6) FIG. 4 shows the bandage prior to use;

(7) FIG. 5 shows an alternative embodiment of the bandage according to the invention;

(8) FIG. 6 shows a modification of the bandage of FIG. 5; and

(9) FIG. 7 shows another alternative embodiment having a combination of the features of the embodiments of FIGS. 1 and 5.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

(10) Referring now in detail to the drawings, FIG. 1 shows a cross-sectional view of the bandage 10 according to the invention after application to a patient's skin 20 for covering a wound 21. Bandage 10 comprises a film layer 11, an adhesive layer 12 extending the length of film layer 11, and an absorbent layer 13 disposed centrally along film layer 11, so that end sections 17 of film layer 11 extend beyond absorbent layer 13. A non-stick layer 14 is applied to the bottom of absorbent layer 13 to prevent absorbent layer 13 from sticking to the wound 21. Non-stick layer 14 is water permeable and can be configured as a screen or with perforations to allow fluid to pass through to absorbent layer 13. Non-stick layer 14 can be configured of any suitable material, such as silicone or polypropylene. Film layer 11 can be manufactured from any suitable film material that is commonly used in disposable bandages. Common film materials are extruded polymers, but woven materials could also be used instead of a film.

(11) Embedded within absorbent layer 13 is a microencapsulated antimicrobial agent 17. The antimicrobial agent 17 is configured to be released from microencapsulation upon contact with fluid, so that the agent can mix with the fluid and kill any microoganisms in the fluid. Absorbent layer 13 can be formed of any suitable material, such as foam or gauze.

(12) Antimicrobial agent 17 can be any suitable agent, such as a topical antibiotic (erythromycin, sulfacetamide sodium, bacitracin, neomycin) or antiseptic (sodium hypochlorite, ethanol, iodine, chlorhexidine). By pulling the fluid out of the wound, bandage 10 prevents infection in the wound and speeds healing.

(13) A plurality of microneedles 15, 16, are disposed in the bandage 10, extending between the absorbent layer 13 and the wound 21. Needles 15 act to absorb fluid 18 from wound 21 and store it in absorbent layer 13. Needles 16 are filled with microencapsulated antimicrobial agent 17, which is released through needles 16 and travels into wound 21 to speed healing. The combined action of needles 15, 16 acts to decrease inflammation and infection, while keeping the wound dry. The needles 15, 16, act as conduits both into and out of the wound 21, so that over time, fluid collecting in the wound area is continually suctioned away and treated, thus decreasing healing time and risk of infection. The needles 15 that absorb the fluid from the wound 21 are attached directly to the absorbent material, and capillary action forces the fluid 18 from the wound 21 up the needles 15, where it is absorbed by the absorbent layer 13. At the same time, the same capillary action that pulls the fluid out of the wound forces the antimicrobial agent 17, which is in liquid form, down the needles 16 and into the wound.

(14) In addition, due to the principle of chemotaxis, any organisms affected by the antimicrobial agent 17 will be driven up the microneedles 15 to the absorbent layer 21, in order to avoid contact with the antimicrobial agent 17.

(15) As shown in FIG. 1, the needles 15, 16 are disposed uniformly throughout the bandage, so that the suction of wound fluid and the dispensing of the antimicrobial agent takes place evenly throughout the area. However, other arrangements could also be used, such as the one in FIG. 2, where all needles 15 are on one side of the bandage 10, and all needles 16 are on the other side, so that suction of the fluid 18 occurs on one side and dispensing of the antimicrobial agent 17 occurs on the other side.

(16) As shown in FIG. 3, there can be a layer of electronic ink 23 disposed on the film layer 11, a battery 22 connected to the electronic film layer, and a moisture sensor 24 connected to the electronic film layer and the absorbent layer, wherein the electronic film layer 23 displays a message when the moisture sensor 24 senses a predetermined level of moisture in the absorbent layer 13, thus indicating time to change the bandage.

(17) As shown in FIG. 4, a release layer 25 can be placed on the bottom of the bandage to protect adhesive layer 12 as well as prevent antimicrobial agent 17 from leaking out of needles 16 prior to use.

(18) An alternative embodiment of the invention is shown in FIGS. 5-6. Here, bandage 100, similar to bandage 10, has a film layer 11, an adhesive layer 12 extending the length of film layer 11, and an absorbent layer 13 disposed centrally along film layer 11, so that end sections 17 of film layer 11 extend beyond absorbent layer 13. Absorbent layer 13 is impregnated with a fluid such as water. Absorbent layer 13 can be a foam, a fabric, a gel or any other layer that can hold a fluid.

(19) A permeable membrane 41 is disposed along the bottom surface of absorbent layer 13, facing wound 21. A plurality of light emitting diodes (LEDs) 40 are arranged along membrane 41, in any suitable pattern: The LEDs 40 could cover the entire wound-facing surface, or only a portion of the surface, and can be arranged with any desired density. One example is shown in FIG. 7, where the LEDs are arranged evenly spaced over the entire membrane 41.

(20) LEDs 40 are connected to each other and to a power storage unit 43, which is also connected to membrane 41. Power storage unit 43 is charged by the electric current generated by osmosis when fluid 18 from wound 21 travels through membrane 41, as shown in FIG. 5. As the less saline fluid 18 from absorbent layer 13 flows through membrane 41 toward the more saline environment of wound 21, an electrical charge is created across the membrane. This charge is stored in power storage unit 43 and used to power LEDs 40. LEDs 40 emit light 48 in the ultraviolet spectrum, which can be effective in disinfecting wound 21 while bandage 100 is covering it. The fluid flowing from absorbent layer 13 into wound 21 could also have disinfecting properties and can be any suitable disinfectant, as long as it passes through membrane 41 to create the current required for power storage unit 43.

(21) To supplement power storage unit 43, a photovoltaic cell 43 can be placed on bandage 100 and connected to power storage unit 43 by a wire 45, as shown in FIG. 6. Solar energy 49 can be absorbed by photovoltaic cell 43, which converts it into electrical energy for storage by power storage unit 43. Power storage unit 43 can also be charged by any other suitable method, or can come pre-charged.

(22) The device shown in FIGS. 5-7 can be combined with the microneedle configurations of FIGS. 1-4, so that a combination of microneedles and LEDs are present in each bandage. The microneedles 15, 16 can be interspersed with the LEDs to provide the antimicrobial agent in addition to the UV light to disinfect the wound, as shown in FIG. 7.

(23) Accordingly, while only a few embodiments of the present invention have been shown and described, it is obvious that many changes and modifications may be made thereunto without departing from the spirit and scope of the invention.