PULLULAN EMPTY HARD CAPSULE AND PREPARATION METHOD THEREFOR

Abstract

A pullulan empty hard capsule and a preparation method therefor. The empty hard capsule includes the following components: 82-89 wt % of pullulan having a pH of 6-7, 1-1.4 wt % of gelling agent, 0.8-1.4 wt % of coagulant aid, 0.01-0.04 wt % of humectant, 0.01-0.04 wt % of surfactant, and 10-14 wt % of purified water. The preparation method for the pullulan empty hard capsule includes: weighing the components; dissolving the gelling agent, the coagulant aid, the humectant, the surfactant, a light-screening agent, a food coloring with 80-90° C. purified water, putting the dissolved substances into a gel dissolving barrel, stirring till the gelling agent is dissolved, adding the pullulan having a pH of 6-7 while stirring, after the pullulan is completely dissolved, cooling, preparing a capsule by means of a glue dipping method, and drying.

Claims

1. A pullulan empty hard capsule, comprising the following components: 82-89 wt % of pullulan having a pH of 6-7; 1-1.4 wt % of a gelling agent; 0.8-1.4 wt % of a coagulant aid; 0.01-0.04 wt % of a humectant; 0.01-0.04 wt % of a surfactant; and 10-14 wt % of purified water.

2. The pullulan empty hard capsule according to claim 1, wherein further comprising a light-screening agent and a food coloring, wherein a content of the light-screening agent is less than 2.6 wt %, and a content of the food coloring is less than 1.7 wt %.

3. The pullulan empty hard capsule according to claim 1, wherein the gelling agent is carrageenan, the humectant is glycerin, the surfactant is sodium lauryl sulfate, the light-screening agent is titanium dioxide, and the coagulant aid is a cationic coagulant aid.

4. A method for preparing the pullulan empty hard capsule according to claim 1, comprising the following steps: step 1. weighing the pullulan, the gelling agent, the coagulant aid, the humectant, the surfactant, the light-screening agent, the food coloring, and the purified water; step 2. dissolving the gelling agent, the coagulant aid, the humectant, the surfactant, the light-screening agent, and the food coloring with the purified water, transferring dissolved substances into a gel dissolving barrel containing 80-90° C. purified water, and stirring until the gelling agent is dissolved; adding the pullulan having a pH of 6-7 while stirring, and incubating for 2-12 hour with stirring once every hour, and after the pullulan is completely dissolved, decreasing temperature to 52-58° C.; preparing a capsule by means of a glue dipping method and drying at 25-40° C., and obtaining the pullulan empty hard capsule when a moisture content of the hard capsule reaches 10-14% by drying.

5. The method for preparing the pullulan empty hard capsule according to claim 4, wherein in the step 2, a stirring speed is 1-5 rpm.

6. The method for preparing the pullulan empty hard capsule according to claim 4, wherein in the step 2, the moisture content of the pullulan empty hard capsule dried is 12.0-12.1%.

7. The method for preparing the pullulan empty hard capsule according to claim 4, wherein in the step 2, the temperature is decreased to 55° C.

Description

DESCRIPTION OF THE EMBODIMENTS

[0018] The present invention is further described in detail below by way of specific examples.

EXAMPLE 1

[0019] 40 kg of 85° C. purified water was added into a gel dissolving barrel. Another 8 kg of purified water was used to dissolve 192 g of carrageenan, 144 g of potassium chloride, 3.2 g of sodium lauryl sulfate, and 5.25 g of glycerin, and then they were poured into the gel dissolving barrel, and stirred until the carrageenan was dissolved, and 12 kg of pullulan having a pH value of 6.72 was slowly added while stirring. Then the glue solution was incubated at 85° C. for about 4 h with stirring once every hour, and then cooled to 55° C. for incubation and defoaming for later use.

[0020] In the production line, a capsule was prepared by means of a traditional dipping method and dried at 25-40° C., to obtain a transparent-appearance empty capsule with a moisture content of 12.1%, and the disintegration time was 7 min.

EXAMPLE 2

[0021] 40 kg of 80° C. purified water was added into a gel dissolving barrel. Another 8 kg of purified water was used to dissolve 192 g of carrageenan, 144 g of potassium chloride, 3 g of sodium lauryl sulfate, and 4.25 g of glycerin, and then they were poured into the gel dissolving barrel, and stirred until the carrageenan was dissolved, and 12 kg of pullulan having a pH value of 6.63 was slowly added while stirring. Then the glue solution was incubated at 85° C. for about 4 h with stirring once every hour, and then cooled to 55° C. for incubation and defoaming for later use.

[0022] In the production line, a capsule was prepared by means of a traditional dipping method and dried at 25-40° C., to obtain a transparent-appearance empty capsule with a moisture content of 12.0%, and the disintegration time was 7 min.

EXAMPLE 3

[0023] 40 kg of 88° C. purified water was added into a gel dissolving barrel. Another 8 kg of purified water was used to dissolve auxiliary materials: 192 g of carrageenan, 144 g of potassium chloride, 2.3 g of sodium lauryl sulfate, and 4.25 g of glycerin, and then they were poured into the gel dissolving barrel, and stirred until the carrageenan was dissolved, and 12 kg of pullulan having a pH value of 6.35 was slowly added while stirring. Then the glue solution was incubated at 85° C. for about 4 h with stirring once every hour, and then cooled to 55° C. for incubation and defoaming for later use.

[0024] In the production line, a capsule was prepared by means of a traditional dipping method and dried at 25-40° C., to obtain a transparent-appearance empty capsule with a moisture content of 12.0%, and the disintegration time was 7 min.

EXAMPLE 4

[0025] 40 kg of 90° C. purified water was added into a gel dissolving barrel. Another 8 kg of purified water was used to dissolve auxiliary materials: 192 g of carrageenan, 144 g of potassium chloride, 2.3 g of sodium lauryl sulfate, and 3.25 g of glycerin, and then they were poured into the gel dissolving barrel, and stirred until the carrageenan was dissolved, and 12 kg of pullulan having a pH value of 6.83 was slowly added while stirring. Then the glue solution was incubated at 85° C. for about 4 h with stirring once every hour, and then cooled to 55° C. for incubation and defoaming for later use.

[0026] In the production line, a capsule was prepared by means of a traditional dipping method and dried at 25-40° C., to obtain a transparent-appearance empty capsule with a moisture content of 12.1%, and the disintegration time was 7 min.

EXAMPLE 5

[0027] 40 kg of 83° C. purified water was added into a gel dissolving barrel. Another 8 kg of purified water was used to dissolve 192 g of carrageenan, 144 g of potassium chloride, 3.2 g of sodium lauryl sulfate, and 3.25 g of glycerin, and then they were poured into the gel dissolving barrel, and stirred until the carrageenan was dissolved, and 12 kg of pullulan having a pH value of 6.17 was slowly added while stirring. Then the glue solution was incubated at 85° C. for about 4 h with stirring once every hour, and then cooled to 55° C. for incubation and defoaming for later use.

[0028] In the production line, a capsule was prepared by means of a traditional dipping method and dried at 25-40° C., to obtain a transparent-appearance empty capsule with a moisture content of 12.1%, and the disintegration time was 7 min.

[0029] The above descriptions are merely preferred embodiments of the present invention, and are not intended to limit the protection scope of the present invention. Simple changes or equivalent replacements to the technical solutions readily apparent to any one skilled in the art within the technical scope disclosed in the present invention shall fall within the protection scope of the present invention.