THERAPEUTIC COMPOSITION FOR ARRESTING, PREVENTING AND REVERSING DENTAL DISEASE

Abstract

The present invention discloses a non-acidic-candy based composition for arresting or reversing dental caries by transforming the oral cavity from an acidic, bacteria-filled environment to an environment more conducive to remineralization by quickly neutralizing the acids recreated by ingestion of acidic compounds or by cariogenic bacteria while supplying necessary ions for tooth remineralization. This improves oral health, prevents pain and suffering, and serves as a conduit to deliver additional therapeutic agents. The composition comprises any combination of a calcium-based compound, a bicarbonate compound, a fluoride compound, an active ingredient, a therapeutic agent based on need, a non-cariogenic sweetener, a hydrating agent, at least one additive, and water. The composition is a candy that has a non-acidic-based composition which neutralizes acids while delivering necessary ions in a pH optimized environment to create the best possible conditions needed to arrest and/or reverse disease processes in the oral cavity and beyond.

Claims

1. A therapeutic composition for improving oral health and delivering nutrients, other agents, or combinations thereof, comprising: at least one fluoride-based compound; at least one calcium-based compound; at least one acid neutralizing agent; at least one active ingredient; at least one tooth whitening agent; at least one probiotic; at least one energy supplement; at least one sweetener; at least one hydrating agent; at least one additive, and at least one agent to assist with halitosis, wherein said composition is configured to neutralize pH in an oral cavity and delivers ions to create an environment that arrests or reverses disease processes.

2. The composition of claim 1, wherein said additive is selected from a group comprising an antimicrobial agent, an antibacterial agent, an antiviral agent, a colorant, and a flavorant.

3. The composition of claim 1, further comprises at least one vitamin or mineral.

4. The composition of claim 1, further comprises at least one electrolyte.

5. The composition of claim 1, wherein said at least one agent to assist with halitosis, is a bacteria.

6. The composition of claim 1, wherein said neutralizing agent is a bicarbonate.

7. The composition of claim 1, further comprises a stimulant, wherein said stimulant is caffeine.

8. The composition of claim 1, provides the best environment for remineralization, wherein the candy composition comprises of a high-intensity sweetener in a range of about 0.001 g to about 0.006 g, fiber in the range of about 2-6 g, β-tricalcium phosphate (β-TCP) in a range of about 0.5 g-5 g, alcohol-based sweetener in the range of about 1-6 g, fluoride-based compound ranging from 0 g to about 0.2 g, bicarbonate in the range of about 0.02 mg to about 20 mg and water.

9. The composition of claim 8, wherein said high-intensity sweetener is stevia, said fiber is nutriose and said alcohol-based sweetener is erythritol.

10. The composition of claim 1, is in a form of soft candy.

11. The composition of claim 10, wherein said form of soft candy is in a form selected from a group comprising, a chewy candy, a gummy candy, or a jelly candy.

12. The composition of claim 1, is in a form of hard candy.

13. The composition of claim 12, wherein said form of hard candy is in a form of lollypop type candy.

14. The composition of claim 1, is in a form of a powder.

15. The composition of claim 14, wherein said form of powder can be added to water to achieve same therapeutic results.

16. A non-acidic-based composition for improving oral health and delivering nutrients, therapeutic agents, or combinations thereof, comprising: at least one fluoride-based compound; at least one calcium-based compound; at least one acid neutralizing agent; at least one active ingredient; at least one tooth whitening agent; at least one probiotic; at least one energy supplement; at least one sweetener; at least one hydrating agent; at least one additive, and at least one agent to assist with halitosis, wherein said composition is configured to neutralize pH in an oral cavity and delivers ions to create an environment that arrests or reverses disease processes.

17. The composition of claim 16, wherein said additive is selected from a group comprising an antimicrobial agent, an antibacterial agent, an antiviral agent, a colorant, and a flavorant.

18. The composition of claim 16, further comprises at least one vitamin or mineral.

19. The composition of claim 16, further comprises at least one electrolyte.

20. The composition of claim 16, wherein said at least one agent to assist with halitosis, is lactobacillus.

21. The composition of claim 16, wherein said acid neutralizing agent is calcium bicarbonate.

22. The composition of claim 16, further comprises a stimulant, wherein said stimulant is caffeine.

23. The composition of claim 16, provides the best environment for remineralization, wherein the candy composition comprises of a high-intensity sweetener in a range of about 0.001 g to about 0.006 g, fiber in the range of about 2-6 g, β-tricalcium phosphate (β-TCP) in a range of about 0.5 g-5 g, alcohol-based sweetener in the range of about 1-6 g, fluoride-based compound ranging from 0 g to about 0.2 g, bicarbonate in the range of about 0.02 mg to about 20 mg and water.

24. The composition of claim 23, wherein said high-intensity sweetener is stevia, said fiber is nutriose and said alcohol-based sweetener is erythritol.

25. The composition of claim 16, is in a form of soft candy.

26. The composition of claim 25, wherein said form of soft candy is in a form selected from a group comprising, a chewy candy, a gummy candy, or a jelly candy.

27. The composition of claim 16, is in a form of hard candy.

28. The composition of claim 27, wherein said form of hard candy is in a form of lollypop type candy.

29. The composition of claim 16, is in a form of a powder.

30. The composition of claim 29, wherein said form of powder can be added to water to achieve same therapeutic results.

31. A non-acidic-based composition for improving oral health and delivering nutrients, therapeutic agents, or combinations thereof, wherein said composition is configured to neutralize pH in the oral cavity and delivers therapeutic agents to create an oral environment that reverses disease processes in the oral cavity and improves general health.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0026] The present subject matter will now be described in detail with reference to the drawings, provided as illustrative examples of the candy to enable those skilled in the art to practice the subject matter. It will be noted that throughout the appended drawings or tables the FIGURES and examples are not meant to limit the scope of the candy to a specific present subject matter or to a single composition but it is designed to be composed of the same ingredients with different concentrations. By using the candy delivery system and varying the composition of various brands of candy are possible by way of interchange of some or all of the described or illustrated elements and, further, wherein:

[0027] FIG. 1 exemplarily illustrates a non-acidic-based composition and the composition is in the form of hard or soft candy or lollypop (100), according to an embodiment of the present invention;

[0028] FIG. 2 exemplarily illustrates an end-user (102) having improved oral health on using the non-acidic-based composition, according to an embodiment of the present invention; and

[0029] TABLE 1 exemplarily illustrates a non-acidic-based composition is in the form of hard or soft candy or lollypop (100).

DETAILED DESCRIPTION OF THE EMBODIMENTS

[0030] The detailed description seen in FIG. 1 is intended as a description of exemplary embodiments in which the presently disclosed subject matter may be practiced. The term “exemplary” used throughout this description means “serving as an example, instance, or illustration,” and should not necessarily be construed as preferred or advantageous over other embodiments. The detailed description includes specific details for providing a thorough understanding of the presently disclosed composition. However, it will be apparent to those skilled in the art that the presently disclosed subject matter may be practiced without these specific details.

[0031] In the present specification, an embodiment showing a singular component should not be considered limiting. Rather, the subject matter preferably encompasses other embodiments including a plurality of the same component, and vice-versa, unless explicitly stated otherwise herein. Moreover, the applicant does not intend for any term in the specification or claims to be ascribed an uncommon or special meaning unless explicitly set forth as such. Further, the present subject matter encompasses present and future known equivalents to the known components referred to herein by way of illustration. The composition will vary according to the desired therapeutic outcome.

[0032] Although the present disclosure describes a non-acidic-based composition for improving oral health and delivering nutrients, therapeutic agents, or combinations thereof, it is to be further understood that numerous changes may arise in the details of the embodiments of the composition. It is contemplated that all such changes and additional embodiments are within the spirit and true scope of this disclosure.

[0033] The following detailed description is merely exemplary in nature and is not intended to limit the described embodiments or the application and uses of the described embodiments. As used herein, the word “exemplary” or “illustrative” means “serving as an example, instance, or illustration.” Any implementation described herein as “exemplary” or “illustrative” is not necessarily to be construed as preferred or advantageous over other implementations. All of the implementations described below are exemplary implementations provided to enable persons skilled in the art to make or use the embodiments of the disclosure and are not intended to limit the scope of the disclosure.

[0034] The present invention discloses a non-acidic-based composition for improving oral health and delivering nutrients, therapeutic agents, or combinations thereof. The composition, immediately upon use, lowers the acidity in the oral cavity to create an environment that arrests or reverses disease processes (i.e., dental caries and periodontal disease) while bringing other benefits to the consumer including, but not limited to, stronger bones and whiter, healthier teeth. The composition is in the form of a non-sugar (sucrose, fructose, or glucose) containing candy with the capacity to deliver various ingredients in a pH-controlled manner, to quickly decrease the acidity of the mouth and deliver the ingredients needed to prevent and/or repair teeth and also provide other therapeutic benefits in a beneficial and/or less destructive manner.

[0035] In one embodiment, the composition comprises at least one calcium-based compound, at least one bicarbonate compound, at least one active ingredient, at least one sweetener, at least one hydrating agent, and at least one additive. The composition further comprises water. In one embodiment, the additive is selected from the group consisting of an antimicrobial agent, an antibacterial agent, an antiviral agent, a tooth whitening agent, a probiotic, an energy supplement, a colorant, caffeine, and a flavorant. In another mixture of encapsulated components, the composition includes at least one of vitamin, mineral, or electrolyte. In one embodiment, the additive is an agent that helps with halitosis/mal-odor (a lactobacillus or other).

[0036] Referring to TABLE 1, the composition includes at least one high-intensity sweetener component in a range of about 0.001 g to about 0.006 g. In yet another embodiment, the composition comprises fiber of about 2-6 g, and β-tricalcium phosphate (β-TCP) in a range of about 0.5 g to about 5 g, and approximately 1-6 g of a sweetener like an erythritol. In yet another composition, the mixture may include a fluoride-based compound ranging from 0 g to about 0.2 g, about 0-5 water, bicarbonate ranging from about 0.02 to about 20 mg, and the amount of probiotic and other therapeu-therapeutic compounds will vary. In one embodiment, the composition is in a form of lollypop (100). In other embodiments, the candy composition can be made in a form of a hard candy, a chewy candy, a gummy candy, or a jelly candy.

[0037] In one embodiment, the candy is a lollypop, and its composition comprises fiber like nutriose of about 4.46 g, sugar alcohol of about 2.52 g, water of about 1.05 g, a fluoride-based compound of about 0.725 g, β-tri-Calcium phosphate of about 0.75 g, high-intensity sweetener compound like Stevia of about 0.038 g, sodium bicarbonate ranging from about 1 mg, a flavorant of about 0.45 g and a colorant.

[0038] Active ingredients in each embodiment will vary based on therapeutic needs. For example, the fluoride-based compound forms harder enamel and inhibits decay; the tooth whitening agents contain an ingredient which will whiten teeth; the probiotics inhibit bacteria causing gum disease; the antiviral and/or antibacterial agents reduce the pathogenicity of the oral cavity, and the vitamins and minerals (the building blocks of the tooth) strengthen teeth and improve oral and general health.

[0039] Today, electrolytes are generally consumed from sports drinks, which are very acidic. This is a great way to intake electrolytes without destructive sugar and/or acid. Similarly, caffeine and other energy-boosting ingredients can be provided without the sugars and acids that increase tooth decay. The addition of bicarbonate can further help buffer against the acids created by consuming acids and/or plaque containing bacteria. In addition, the candy composic-omposition aids therapeutic agent delivery.

[0040] FIG. 2 exemplarily illustrates an end-user (102) with improved oral health using the non-acidic-based composition, according to an embodiment of the present invention. The candy dissolves in the oral cavity quickly decreases oral acidity and releases beneficial ingredients. Thereby, the composition creates a favorable oral environment for oral health including remineralization of the tooth, leading to the reversal of cavities and other diseases while also being able to deliver other beneficial ingredients.

[0041] In one formulation, the dosage of the therapeutic agents/ingredients of the composition may vary based on desired outcomes, timed release of therapeutic agents, and tailored for subjects of different ages. In different formulations, the candy may be supplied in different flavors and consistencies to appeal to different tastes and unique needs. In addition, the composition is safe for children and diabetics without gastric distress created by alcohol sugars and/or side effects of other sweeteners. Furthermore, it is safe for pets (unlike xylitol containing sweeteners).

[0042] In one embodiment, the composition of the present invention may vary depending on the condition being addressed. In another embodiment, the ingredients of the composition are microencapsulated and/or directly mixed into the candy. As the candy is consumed, the therapeutic agent is delivered in a controlled fashion without the harmful effects of sug-sugar and acid commonly associated with candy.

[0043] The composition is configured to alter the oral environment by adding elements including, but not limited to, calcium, phosphate, and buffering ions. The composition is configured to deliver ions required for oral health simultaneously while being separated during delivery utilizing microencapsulation. The composition is configured to decrease acidity, increase salivary flow, and offer a tasty and effective means to significantly change the oral environment to quickly stop the demineralization and enhance remineralization.

[0044] The composition is configured to quickly reduce the acidity of the oral environment while delivering agents that promote oral and general health. The non-acidic-based composition acts as a vehicle to deliver different therapeutic agent using a candy delivery system that would quickly decrease the acidity of the oral environment, increase saliva flow and improve oral and general health without the adverse effects associated with sugar containing candy in the oral environment.

[0045] The non-acidic-based composition is configured to reduce the acidity of the oral environment quickly. In addition, the composition is configured to provide a sustained release of therapeutic calcium, phosphate, and fluoride ions into the oral cavity for the highest therapeutic impact to reduce or eradicate cariogenic challenge in plaque following sucrose intake. In addition, the composition comprises erythritol and other similar sweeteners that have proven to reduce bacteria and plaque in the oral cavity. The released calcium, phosphate, and fluoride ions can diffuse into partially demineralized tooth enamel or dentin, leading to remineralization and repair of the caries lesion. These ions can also precipitate in dentinal tubules and relieve sensitive teeth. The non-acidic-based composition as a delivery system aids compliance and pleasure while improving health and reducing costs to the user, the payor, and the government by reducing the cost of treatment, thus creating significant savings for all in terms of health and wealth while improving wellbeing. This composition is ideal for use after a meal when one cannot brush their teeth, for snacking, and the perfect solution to reduce decay in elderly populations, particularly in a nursing home environment. The life expectancy of dental restoration is about ten years, but a tooth that has been remineralized can last a lifetime without the need for continued treatment.

[0046] In the above description, numerous specific details are set forth such as examples of some embodiments, specific components, devices, methods, in order to provide a thorough understanding of embodiments of the present disclosure. It will be apparent to a person of ordinary skill in the art that these specific details need not be employed and should not be construed to limit the scope of the disclosure.

[0047] In the development of any actual implementation, numerous implementation-specific decisions must be made to achieve the developer's specific goals, such as compliance with system-related and business-related constraints. Such a de-development effort might be complex and time-consuming, but is nevertheless a routine undertaking of design, fabrication, and manufacture for those of ordinary skill. Hence as various changes could be made in the above constructions without departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the explanation, table, and accompanying drawings shall be interpreted as illustrative and not in a limiting sense.

[0048] The foregoing description of embodiments is provided to enable any person skilled in the art to make and use the subject matter. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the novel principles and subject matter disclosed herein may be applied to other embodiments without the use of the innovative faculty. The claimed subject matter set forth in the claims is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein. It is contemplated that additional embodiments are within the spirit and true scope of the disclosed subject matter.