J30028USw 190058-0591

Abstract

A hair treatment composition comprising a mixture of amino acids, wherein the mixture of amino acids comprises glutamic acid, alanine and proline.

Claims

1. A hair rinse-off treatment composition comprising a mixture of amino acids, wherein: the mixture of amino acids comprises glutamic acid, alanine, and proline; the mixture has a weight ratio of glutamic acid:alanine:proline of 2:1:1 to 1:2:1 to 1:1:2; and the mixture of amino acids is 0.1 to 10% by weight of the total composition.

2. The composition as claimed in claim 1, wherein the composition comprises a surfactant.

3. The composition as claimed in claim 1, wherein the composition is a shampoo or a conditioner.

4. The composition as claimed in claim 1, wherein the composition has a pH in the range of from 3 to 7.

5. A method of treating chemically damaged hair comprising the step of applying to the hair a treatment composition comprising: a mixture of amino acids, wherein: the mixture of amino acids comprises glutamic acid, alanine, and proline; the mixture has a weight ratio of glutamic acid:alanine:proline of 2:1:1 to 1:2:1 to 1:1:2; and the mixture of amino acids is 0.1 to 10% by weight of the total composition.

6. The method as claimed in claim 5, wherein the chemically damaged hair is damaged by bleaching treatments, colouring treatments, straightening treatments, relaxing treatments, surfactant treatments, hot water from 20 to 45° C. and mixtures thereof.

7. The method as claimed in claim 6, further comprising the step of leaving the composition on the hair for 2 seconds to 20 minutes.

8. The method as claimed in claim 5, wherein the method further comprises the step of repeating the application of the composition to the hair.

9. The method as claimed in claim 8, wherein the step of repeating the application of the composition to the hair is made during a later treatment and is repeated 1 to 10 times.

10-11. (canceled)

12. The composition as claimed in claim 1, wherein the weight ratio of glutamic acid:alanine:proline is 1:1:1.

13. The composition as claimed in claim 1, wherein the mixture of amino acids is from 0.2 wt % to 5 wt %, by total weight of the composition.

14. The composition as claimed in claim 1, wherein the mixture of amino acids is from 0.25 wt % to 2 wt %, by total weight of the composition.

Description

EXAMPLES

Example 1—Preparation of Shampoo Compositions, Shampoo 1 & Shampoo 2, in Accordance with the Invention and of Comparative Shampoos, Shampoo a & Shampoo B

[0131] Shampoos 1 and 2, in accordance with the invention contained a 1:1:1 wt mixture of the amino acids glutamic acid, alanine and proline. Shampoos A and B were the same as Shampoos 1 and 2, only without the amino acids.

[0132] All the shampoos were prepared using the following method:

[0133] 1. In the compositions in accordance with the invention, the amino acids (glutamic acid, alanine and proline) were added to water in a suitable vessel, with stirring.

[0134] 2. Any Carbopol was then added.

[0135] 3. SLES and CAPB were then added.

[0136] 4. The mixture was heated to 30° C. and mixed until completely homogenous.

[0137] 5. Any guar polymer was then added and mixed well.

[0138] 6. Fragrance was then added.

[0139] 7. Silicone conditioning agent was added, if using, and mixed.

[0140] 8. Hydrolysed protein was added, if using.

[0141] 9. The pearliser was then added.

[0142] 10. The preservatives were added.

[0143] 11. The pH was adjusted to pH 4 to 5 using a mixture of 50% sodium hydroxide/50% citric acid.

[0144] 12. Salt and polypropylene glycol were then added to adjust the viscosity as desired.

[0145] Shampoo 1 and Shampoo A were prepared with a viscosity in the range of from 9,000 to 15,000 cps (as measured by a Brookfield viscosmeter, rv 5 spindle at 20 rpm for 1 minute at 30° C.).

[0146] Shampoo 2 and Shampoo B were prepared with a viscosity in the range of from 5,000 to 9,000 cps (as measured by a Brookfield viscosmeter, rv 5 spindle at 20 rpm for 1 minute at 30° C.).

[0147] The compositions of Shampoo 1, Shampoo 2, Shampoo A and Shampoo B are shown in Table 1 below:

TABLE-US-00001 TABLE 1 Compositions of Shampoos 1 & 2 and Shampoos A & B Amount (wt % of 100% active) Shampoo Shampoo Shampoo Shampoo Ingredient 1 A 2 B Carbopol 980 — — 10.0 10.0 Sodium Lauryl 13.5 13.5 22.0 22.0 Ether Sulphate (SLES) + cocamidopropyl betaine (CAPB) Guar polymer — — 0.2 0.2 Pearliser 1.2 1.2 2.0 2.0 Silicone — — 1.7 1.7 conditioning agent* Fragrance 0.8 0.8 0.8 0.8 Hydrolysed Protein 2.3 2.3 — — Glutamic Acid 0.67 — 0.67 — Alanine 0.67 — 0.67 — Proline 0.67 — 0.67 — Preservative 0.55 0.55 0.55 0.55 Sodium hydroxide To pH to pH pH to pH Citric acid soln To pH to pH pH to pH Polypropylene To To To To glycol (PPG) viscosity viscosity viscosity viscosity and salt Water To 100 To 100 To 100 To 100 *Dimethicone, ex Dow Corning

Example 2—Preparation of Conditioner Compositions, Conditioner 1, Conditioner 2 and Conditioner 3 in Accordance with the Invention and of Comparative Conditioners, Conditioner a, Conditioner B and Conditioner C

[0148] Conditioners 1, 2 and 3 in accordance with the invention contained a 1:1:1 wt mixture of the amino acids glutamic acid, alanine and proline. Conditioners A, B and C were the same as Conditioners 1, 2 and 3 respectively, only without the amino acids.

[0149] The conditioners were prepared using the following method: [0150] 1. Water was added to a suitable vessel and heated to 80° C. [0151] 2. Cetearyl alcohol was then added to the formulation along with tertiary amine salt (TAS) (if present in the formulation). [0152] 3. The formulation was allowed to cool to 80° C. the Behenyl Trimethyl Ammonium Chloride (BTAC) was added and the resultant mixture mixed until opaque and thick. [0153] 4. If TAS was present in the formulation, lactic acid was added and the formulation was stirred for a further 10 minutes. [0154] 5. The heat was then turned off and the quench water was added. [0155] 6. The amino acids were added.

[0156] 7. The mixture was then cooled to below 55° C. and the EDTA and NaCl were added, as a predissolved pre mix. [0157] 8. Once the formulation had cooled to below 40° C. the rest of the materials, including fragrance, were added. [0158] 9. Finally the formulation was mixed at high shear on a Silverson mixer at 5000 rpm for 5 minutes.

[0159] The compositions of Conditioners 1, 2 and 3, and Comparative Conditioners A, B and C are shown in Table 2 below:

TABLE-US-00002 TABLE 2 Compositions of Conditioners 1, 2 and 3, and Comparative Conditioners A, B and C Amount (wt % of 100% active) Conditioner Conditioner Conditioner Conditioner Conditioner Conditioner Ingredient 1 A 2 B 3 C Quaternary 1.25 1.25 1.0 1.0 2.3 2.3 surfactant* TAS** 1.25 1.25 1.0 1.0 — — FATTY ALC 5.0 5.0 4.0 4.0 3.2 3.2 Conditioning 1.4 1.4 2.14 2.14 1.4 1.4 silicone*** Lactic acid 1.1 1.1 0.85 0.85 — — Preservative 0.5 0.5 0.5 0.5 0.5 0.5 Glutamic 0.33 — 0.66 — 0.33 — acid Alanine 0.33 — 0.66 — 0.33 — Proline 0.33 — 0.66 — 0.33 — Fragrance 1.0 1.0 1.0 1.0 1.0 1.0 Water To 100 To 100 To 100 To 100 To 100 To 100 *Genamin BTLF, ex Clariant **Lexamine s13, ex Inolex ***Dimethicone, ex Dow Coming

Example 3—Preparation of a Gel Composition, Gel 1, in Accordance with the Invention and of a Comparative Gel, Gel A

[0160] Gel 1, in accordance with the invention contained a 1:1:1 wt mixture of the amino acids glutamic acid, alanine and proline. Comparative Gel A was the same as Gel 1, only without the amino acids.

[0161] The gels were prepared using the following method:

[0162] The ingredients were added to a suitable vessel, from highest percentage inclusion to the lowest.

[0163] The final addition was the thickening polymer. The resultant mixture was stirred at 30° C.

[0164] The compositions of Gel 1 and Gel A are shown in Table 3 below.

TABLE-US-00003 !TABLE 3 Compositions of Gel 1 and Gel A Amount (wt % of 100 % active) Ingredient Gel 1 Gel A Propylene Glycol 5.0 5.0 Hydrolysed Collagen 11.0 11.0 Hydrolyzed Elastin 3.0 3.0 Polyacrylamide polymer Thickener 40.0 40.0 Preservative 0.2 0.2 Hydrolysed Keratin 20 1.2 1.2 L-Glutamic acid 0.34 — Alanine 0.33 — Proline 0.33 — Water To 100 To 100

Example 4: Measurement of the Denaturation Temperatures and Change in Denaturation Temperature of Hair, Using Differential Scanning Calorimetry (DSC), to Give an Indication of the Level of Damage in Hair Treated with Shampoo 1 & Shampoo 2, in Accordance with the Invention and of Comparative Shampoos, Shampoo a & Shampoo B Conditioner 1, Conditioner 2 and Conditioner 3 in Accordance with the Invention and of Comparative Conditioners, Conditioner a, Conditioner B and Conditioner C

[0165] The internal protein of damaged hair typically has a reduced denaturation temperature compared to that of virgin hair. Damage repair is evidenced by an increase in the denaturation temperature of the internal protein of hair.

[0166] The Hair

[0167] Virgin:

[0168] The hair used in the following examples was dark brown European hair tresses 5 grams and 10 inches long.

[0169] Double-Bleached:

[0170] Virgin hair tresses were bleached according to the following protocol. Hair was bleached twice for 30 minutes with Platine Precision White Compact Lightening Powder (L'Oreal Professional Paris, Paris, France) mixed with 9% cream peroxide, 30 ‘vol’ (Excel GS Ltd, UK) (60 g of powder mixed with 120 g cream peroxide). Hair was then washed with 14% SLES solution after the second treatment before drying.”

[0171] Treatment of the Hair

[0172] Hair was given a preliminary wash as follows:

[0173] Hair was immersed in water for 30 s before being immersed in 14% aq sles solution. The hair was rubbed for 30 s, rinsed for 30 s and then treated with a non-conditioning shampoo, using 0.1 ml/1 g hair, with rubbing for 30 s and rinsing for 30 s.

[0174] The hair (virgin and double bleached) was then treated with the compositions as detailed in Examples 1 and 2 above, using the following method:

[0175] The shampoo composition was applied to hair in an amount of 0.1 ml/1 g hair and rubbed for 30 seconds to lather, followed by 30 seconds rinse in tap water.

[0176] The conditioner composition was applied to hair in an amount of 0.2 ml/1 g hair and rubbed for 60 seconds, followed by a 60 seconds rinse in tap water.

[0177] The hair tresses were then left to dry overnight at 20° C. at 50% relative humidity.

[0178] The effect of the treatments was measured using Differential Scanning calorimetry (DSC). The bottom 2 cm of the treated hair switches was removed using scissors. The hair was then chopped small using hair clippers. 7-10 mg of the clippings were added to the aluminium pans of the calorimeter, along with 50 μL of water. In all cases 5 hair switches were used per treatment and 1 pan was prepared per hair switch. The prepared pans were allowed to sit overnight before being run on the DSC from 100-180° C., at a rate of 5° C./min.

TABLE-US-00004 TABLE 5 Mean denaturation temperatures for double bleached hair treated with Compositions Shampoo 1 & Shampoo 2, in accordance with the invention and of comparative shampoos, Shampoo A & Shampoo B Conditioner 1, Conditioner 2 and Conditioner 3 in accordance with the invention and of comparative conditioners, Conditioner A. Conditioner B and Conditioner C Statistical Grouping Denaturation Standard Tukey Kramer Treatment Temperature Deviation (p < 0.05) Conditioner A 144.417 0.249065 D,E 1 wash Conditioner A 145.018 0.632844 C,D 5 washes Conditioner 1 143.51 0.683959 E 1 wash Conditioner 1 146.498 0.27127 B,C 5 washes Conditioner B 143.68 1.125033 D,E 1 wash Conditioner B 146.1467 0.748151 B,C 5 washes Conditioner 2 150.42 0.572974 1 wash Conditioner 2 148.786 0.748151 A 5 washes Conditioner C 143.68 1.125033 D,E 1 wash Conditioner C 146.1467 0.748151 B,C 5 washes Conditioner 3 147.9 0.127279 A,B 1 wash Conditioner 3 147.0767 0.291433 B 5 washes Double bleached 144.41 0.27074 D,E (control) Virgin (control) 146.423 0.28219 B,C

[0179] It will be seen that damage repair, shown by an increase in the denaturation temperature, occurs with treatment by the shampoo compositions in accordance with the invention.

[0180] Shampoos

TABLE-US-00005 Statistical Grouping Tukey Denaturation Standard Kramer Treatment Temperature Deviation (p < 0.05) Shampoo A 146.567 0.506195 C 1 Wash Shampoo A 148.17 0.5781 B 5 washes Shampoo 1 147.864 0.872829 B 1 wash Shampoo 1 149.615 0.279583 A 5 washes Shampoo B 145.9325 0.179141 C 1 wash Shampoo B 146.0925 0.236132 C 5 washes Shampoo 2 146.74 0.422137 C 1 wash Shampoo 2 150.01 0.141421 A 5 washes Double bleached 144.41 0.27074 D (control) Virgin (control) 146.423 0.28219 C

[0181] It will be seen that damage repair, shown by an increase in the denaturation temperature, occurs with treatment by the conditioner compositions in accordance with the invention.