Solid Cleansing Compositions and Methods for the Same
20210267878 · 2021-09-02
Assignee
Inventors
- Qiang WU (Hillsborough, NJ, US)
- Shujiang CHENG (Warren, NJ, US)
- Juliana Nwosisi (Scotch Plains, NJ, US)
- Laurence Du-Thumm (Princeton, NJ)
Cpc classification
A61K8/64
HUMAN NECESSITIES
A61K8/361
HUMAN NECESSITIES
International classification
A61K8/92
HUMAN NECESSITIES
A61K8/64
HUMAN NECESSITIES
Abstract
Solid cleansing compositions and methods for the same are disclosed herein. The solid cleansing compositions may include a soap, a plant oil, and a hydrolyzed protein. The plant oil and the hydrolyzed protein may be present in an effective amount to maintain or increase hydration of skin. The plant oil may be or include a flaxseed oil, and the hydrolyzed protein may be or include a hydrolyzed milk protein.
Claims
1. A solid cleansing composition, comprising a soap, a plant oil, and hydrolyzed protein, wherein the plant oil and the hydrolyzed protein are present in an effective amount to maintain or increase hydration of skin.
2. The solid cleansing composition of claim 1, wherein the plant oil comprises flaxseed oil.
3. The solid cleansing composition of claim 1, wherein the hydrolyzed protein comprises hydrolyzed milk protein, optionally, the hydrolyzed milk protein is present in an amount of from greater than 0 weight % to about 1 weight %, optionally, from about 0.15 weight % to about 0.3 weight %, further optionally, from about 0.2 weight % to about 0.25 weight %, based on a total weight of the solid cleansing composition.
4. The solid cleansing composition of claim 2, wherein the plant oil is present in an amount of from greater than 0 weight % to less than or equal to 5 weight %, optionally, in an amount of from greater than 0 weight % to less than or equal to 1 weight %, further optionally, in an amount of about 0.5 weight %.
5. The solid cleansing composition of claim 1, wherein a weight ratio of the plant oil to the hydrolyzed protein is about 2.0:1 to about 2.5:1, optionally, about 2.1:1 to about 2.4:1, about 2.2:1 to about 2.3:1, or about 2.27:1.
6. The solid cleansing composition of claim 1, wherein the soap comprises sodium soap, optionally the soap further comprises one or more of an ammonium soap, a potassium soap, a magnesium soap, and a calcium soap.
7. The solid cleansing composition of claim 1, wherein the hydrolyzed protein is provided by an aqueous hydrolyzed protein solution comprising hydrolyzed milk protein and water, optionally, the hydrolyzed milk protein is present in an amount of about 18 weight % to about 25 weight %, based on a total weight of the aqueous hydrolyzed protein solution.
8. The solid cleansing composition of claim 1, wherein the soap comprises alkali metal salts of aliphatic acids having 8 to 22 carbon atoms.
9. The solid cleansing composition of claim 1, further comprising one or more humectants, optionally, the one or more humectants are selected from ascorbic acid, ascorbyl dipalmitate, acetamide MEA, glucose glutamate, glucuronic acid, TEA-lactate, TEA-PCA, corn syrup, fructose, glucose, glycerin, glycol, 1,2,6-hexanetriol, sodium lactate, sodium PCA, hydrogenated starch hydrolysate, inositol, lactic acid, lactose, mannitol, PCA, PEG-10 propylene glycol, polyamino sugar condensate, propylene glycol, pyridoxine dilaurate, saccharide hydrolysate, hydroxystearyl methylglucamine, glucamine, maltitol, mannitol, methyl gluceth-10, methyl gluceth-20, riboflavin, PEG-4, PEG-6, PEG-8, PEG-9, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18, PEG-20, PEG-32, PEG-40, glutamic acid, glycereth-7, glycereth-12, glycereth-26, saccharide isomerate, sorbeth-20, sorbitol, sucrose, thioglycerin, tris-(hydroxymethyl)nitromethane, tromethamine, histidine, PEG-75, PEG-135, PEG-150, PEG-200, PEG-5 pentaerythritol ether, polyglyceryl sorbitol, sorbitol, urea, xylitol, and combinations thereof.
10. The solid cleansing composition of claim 9, further comprising one or more free fatty acids, optionally, wherein the one or more free fatty acids are selected from palm kernel oil, palm oil, coconut oil, olive oil, laurel oil, and combinations thereof.
11. The solid cleansing composition of claim 1, wherein the solid cleansing composition is a bar soap.
12. A method for maintaining or increasing hydration of skin of a user, comprising contacting the solid cleansing composition of claim 1 with the skin of the user in need thereof.
13. Use of the solid cleansing composition of claim 11 for maintaining or increasing hydration of skin.
14. A method for preparing a solid cleansing composition, comprising: contacting an effective amount of a plant oil and an effective amount of hydrolyzed protein with one another to prepare a mixture; and contacting a soap with the mixture, wherein the effective amounts of the plant oil and the hydrolyzed protein is an amount effective to maintain or increase hydration of skin, optionally, wherein the plant oil comprises flaxseed oil, further optionally, wherein the hydrolyzed protein comprises hydrolyzed milk protein.
15. The method of claim 14, wherein the plant oil is present in an amount of from greater than 0 weight % to less than or equal to 1 weight %, and wherein the hydrolyzed protein is present in an amount of from greater than 0 weight % to less than or equal to 2 weight %, based on a total weight of the solid cleansing composition.
Description
EXAMPLES
[0057] The examples and other implementations described herein are exemplary and not intended to be limiting in describing the full scope of compositions and methods of this disclosure. Equivalent changes, modifications and variations of specific implementations, materials, compositions and methods may be made within the scope of the present disclosure, with substantially similar results.
Example 1
[0058] A base bar soap composition or control (1) in the form of a plurality of soap chips was prepared by combining the ingredients/components according to Table 1. Three test bar soap compositions (2)-(4) were then prepared by adding varying amounts of flaxseed oil and hydrolyzed milk protein solution (MILK TEIN NPNF®, about 18 weight % to about 25 weight % hydrolyzed milk protein in water) to the control, according to Table 2. The hydrolyzed milk protein solution (MILK TEIN NPNF®) was obtained from Tri-K Industries, Inc. of Denville, N.J.
TABLE-US-00001 TABLE 1 Composition of Base Bar Soap Composition Ingredient/Component Amount (wt %) Soap chips containing sodium palmitate, 76.3 sodium oleate and sodium laurate Glycerin 7.3 Demineralized water 15 Perfume 1.4
TABLE-US-00002 TABLE 2 Compositions of Control and Test Bar Soap Compositions (1)-(4) Base Bar Soap Flaxseed Hydrolyzed Milk Composition Oil Protein Solution # (wt %) (wt %) (wt %) (1) 100.0 0.0 0.0 Control (2) 99.5 0.5 0.0 (3) 99.0 0.0 1.0 (4) 98.5 0.5 1.0
Example 2
[0059] Each of the control (1) and test (2)-(4) bar soap compositions was studied in vitro with skin tissue models to evaluate the hydration properties thereof. Pigskins were used as the skin models for each of the bar soap compositions (1)-(4). Particularly, 1.5 square inch samples of pig skin were cut from the same piece of pig skin and separated into four test group to test each of the four bar soap composition (1)-(4). Each of the bar soap compositions (1)-(4) was used to treat twelve pig skin models. To evaluate the hydration properties, a pig skin was placed in a petri dish and wetted under running water maintained at about 95° F. (about 35° C.) for several seconds. One of the bar soap compositions (1)-(4) was then rotated by hand under the running water maintained at about 95° F. (about 35° C.) for about 5 seconds. The wetted bar soap composition (1)-(4) and the wetted pig skin were then contacted with one another for about 10 seconds, and subsequently lathered with a gloved finger for about 15 seconds. The resulting lather was left on the skin for about 30 seconds prior to rinsing under the water (about 95° F. or about 35° C.) for about 15 seconds. The rinsed pig skin was then dried in air for about 30 minutes. The process was repeated two more times to provide a total of three washing treatments. After the pig skin was exposed to three washing treatments, the pig skin was stored overnight at about 40% relative humidity (RH) at about 70° F. (about 21° C.).
[0060] After storing overnight, water content measurements or hydration properties of each of the bar soap compositions (1)-(4) on the skin models were quantified via confocal Raman spectroscopy or microscopy (Model 3510 from River Diagnostics, Rotterdam, the Netherlands). The water concentration (weight %) of skin was measured to a depth of 50 μm in 2 μm increments. The acquisition time was 1 second/step in the spectral region of from about 2500 cm .sup.−1 to about 4000 cm.sup.−1. The concentration of water (weight %) was determined automatically through the built-in software provided by the instrumentation and a water profile curve that was obtained.
[0061] The results of the water content measurements or hydration properties of each of the bar soap compositions (1)44) on the skin models were obtained via integration of a water profile curve (area under the curve) and are summarized in Table 3.
TABLE-US-00003 TABLE 3 Water Content Measurements of Bar Soap Compositions (1)-(4) Average Δ Water Water Content vs. Content Std Control # (weight %) Dev. (%) (1) 2615 275.4 — Control (2) 2589 302.5 −26 0.5 wt % Flaxseed Oil (3) 2601 235.2 −14 1% of Hydrolyzed Milk Protein Solution (providing about 0.18% to about 0.25% Hydrolyzed Milk Protein, based on a total weight of the bar soap composition) (4) 2755 214.8 +140 0.5 wt % Flaxseed Oil and 1 wt % Hydrolyzed Milk Protein Solution (providing about 0.18% to about 0.25% Hydrolyzed Milk Protein, based on a total weight of the bar soap composition)
[0062] As illustrated in Table 3, the bar soap composition including 0.5 wt % flaxseed oil (2) decreased water content or hydration of skin relative to the control (1). Similarly, the bar soap composition including 1 weight % of hydrolyzed milk protein (3) decreased water content or hydration of skin relative to the control (1). As such, it was surprisingly and unexpectedly discovered that the bar soap composition including a combination of flaxseed oil and hydrolyzed milk protein (4), both of which individually decreased the relative water content or hydration of skin, significantly increased the hydration of skin relative to the control (1). Further, the ability.sup., to increase the hydration of skin in a bar soap was surprising and unexpected, as bar soaps generally dry skin, as opposed to liquid cleansing compositions (e.g., shower gels), which are generally capable of increasing hydration of skin.
[0063] The present disclosure has been described with reference to exemplary implementations. Although a limited number of implementations have been shown and described, it will be appreciated by those skilled in the art that changes may be made in these implementations without departing from the principles and spirit of the preceding detailed description. It is intended that the present disclosure be construed as including all such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.