Protective cap for a dispenser and dispenser for discharging pharmaceutical and/or cosmetic liquids

Abstract

A protective cap for a dispenser for discharging pharmaceutical and/or cosmetic liquids. The dispenser has a liquid reservoir and a discharge opening through which the liquid can be dispensed into a surrounding atmosphere. The protective cap has at least one ventilation opening for establishing communication between an interior and an outer surrounding area, and a sterile filter which covers the at least one ventilation opening is arranged on the protective cap in order to reduce or prevent an introduction of microbes into the interior of the protective cap via the at least one ventilation opening.

Claims

1. A discharging device comprising: a dispenser for discharging pharmaceutical and/or cosmetic liquids, the dispenser having a liquid reservoir and an exit opening through which the liquid can be discharged into a surrounding atmosphere; and a protective cap having at least one ventilation opening in order for an interior to communicate with exterior surroundings, wherein the protective cap has arranged thereon a sterile filter which covers the at least one ventilation opening so as to reduce, or to prevent, introduction of germs into the interior of the protective cap via the at least one ventilation opening; wherein the sterile filter is designed in the form of a microporous polymer membrane, made of a membrane polymer from the group comprising polysulfone, polyethersulfone, cellulose, cellulose derivatives, polyvinylidene fluoride, polyamide, polyester and polyacrylonitrile and/or combinations thereof; and wherein the sterile filter is applied to a carrier layer functioning as absorber surface, the carrier layer being arranged such that, during use, the carrier layer is in contact with the exit opening of the dispenser.

2. The discharging device as claimed in claim 1, wherein the sterile filter has an average pore diameter or a cutoff of at most approximately 0.1 μm to approximately 0.3 μm.

3. The discharging device as claimed in claim 1, wherein the sterile filter has an average pore diameter or a cutoff of at most approximately 0.2 μm.

4. The discharging device as claimed in claim 1, wherein the sterile filter is latched to a wall of the protective cap.

5. The discharging device as claimed in claim 1, wherein the protective cap comprises a cylindrical portion and a cover portion connected thereto, wherein the at least one ventilation opening is provided on the cover portion.

6. The discharging device as claimed in claim 5, wherein latching arms, which project from an inner side of the cover portion, are provided for fastening the sterile filter.

7. The discharging device as claimed in claim 1, wherein the carrier layer is provided as a gas-permeable, hydrophilic carrier layer.

8. The discharging device as claimed in claim 1, wherein the dispenser has an outlet channel which connects the liquid reservoir to the exit opening and an outlet valve which opens in a pressure-dependent manner or is manually actuable, is arranged in the outlet channel and, in a closed state, closes the outlet channel.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

(1) Further advantages and aspects of the invention can be gathered not just from the claims, but also from the following description of preferred exemplary embodiments of the invention, which will be explained hereinbelow with reference to the figures. The drawings use like reference signs to denote the same or similar components. Features illustrated or described as part of an exemplary embodiment can likewise be used in a different exemplary embodiment in order to achieve a further embodiment of the invention. In the drawings:

(2) FIG. 1 shows a sectional illustration of a dispenser for discharging pharmaceutical and/or cosmetic liquids.

(3) FIG. 2 shows the outlet subassembly according to FIG. 1 with a protective cap according to a first exemplary embodiment.

(4) FIG. 3 shows an overall perspective illustration of a discharging device comprising a dispenser and a protective cap.

(5) FIG. 4 shows a sectional illustration of the discharging device according to FIG. 3.

(6) FIG. 5 shows an overall perspective illustration of an alternative configuration of a discharging device comprising a dispenser and a protective cap.

(7) FIG. 6 shows a sectional illustration of the discharging device according to FIG. 5.

DETAILED DESCRIPTION OF THE EXEMPLARY EMBODIMENTS

(8) FIG. 1 shows, in the first instance, a dispenser 2 which is intended for discharging pharmaceutical and/or cosmetic liquids and is suitable, in particular, for unpreserved ophthalmic preparations.

(9) Said dispenser 2 has a liquid reservoir 21, which is delimited by a container body 20. The liquid 4 is stored in the liquid reservoir 21. An outlet subassembly 22 has been placed in position, and fastened by means of a latching connection, on the container body 20. Said outlet subassembly 22 serves for directing liquid from the liquid reservoir 21 to an exit opening 24 through an outlet channel 23. The exit opening 24 illustrated is configured in the form of a droplet-forming surface and widens conically in the discharging direction.

(10) On account of the section plane in FIG. 1, the latter illustrates merely a final part of the outlet channel 23. The outlet channel 23 has arranged in it an outlet valve 25 which, in a closed state, closes the outlet channel 23, and therefore liquid located downstream of the outlet valve 25, as seen in the discharging direction, cannot pass back into the liquid reservoir 21. The outlet valve 25 illustrated comprises a valve body 27, which can be adjusted counter to the force of a restoring spring 26 and interacts with a valve seat 28 formed on a housing wall. Air flows into the liquid reservoir 21, for pressure-equalization purposes, via a filter element 29. In advantageous configurations, the filter element 29 comprises a liquid filter, which is oriented in the direction of the liquid reservoir 21, and a bacteria filter, which is oriented away from the liquid reservoir 21 and has a cutoff of approximately 0.2 μm, so that bacteria of a size of approximately 0.2 to approximately 5 μm are reliably held back by the bacteria filter.

(11) The dispenser 2 illustrated is configured in the form of a so-called squeeze bottle. Said dispenser 2 is used by being placed upside down with the exit opening 24 oriented downward. Thereafter, walls of the container body 20 are pressed together in order for the liquid 4 in the liquid reservoir 21 to be subjected to pressure. This pressure causes the outlet valve 25 to open. More specifically, as soon as the liquid pressure in a part of the outlet channel 23 upstream of the outlet valve 25 is sufficiently high, the valve body 27 shifts counter to the force of the restoring spring 26 as a result of said pressure and frees the path for the liquid in the direction of the exit opening 24.

(12) Following a discharging operation, the outlet valve 25 is closed again. It is usual here for a residue of the liquid, the so-called residual droplet, to remain at the exit opening 24, configured in the form of the droplet-forming surface, and in a part of the outlet channel 23 assigned to the exit opening 24 and located downstream of the outlet valve 25 as seen in the discharging direction. The outlet valve 25, which opens in a pressure-dependent manner, precludes any possibility of the liquid flowing back into the liquid reservoir 12.

(13) Without a protective cap being placed in position, the residual droplet can dry up rapidly. In order to make it possible for rapid drying also to take place when the protective cap has been placed in position, protective caps of the type in question have at least one ventilation opening.

(14) FIG. 2 shows the outlet subassembly 22 with a protective cap 3 placed in position thereon. The protective cap 3 illustrated has a plurality of ventilation openings 30 in order for an interior 31 to communicate with exterior surroundings. The protective cap 3 comprises an essentially cylindrical portion 32 and a cover portion 33 connected thereto. In the case of the protective cap 3 according to FIG. 2, the ventilation openings 30 are provided on the cover portion 33. The number of ventilation openings 30 can be selected appropriately by a person skilled in the art. In the embodiment according to FIG. 2, the protective cap 3 has three uniformly distributed ventilation openings 30, of which only one can be seen in FIG. 1. The protective cap 3 is produced in the form of an injection molding and has a tamperproof seal 34, which has to be removed when the dispenser is used for the first time. Latching elements 35 for latching to the dispenser 2 according to FIG. 1 are provided on an inner wall. The latching elements 35 here are configured such that they prevent the protective cap 3 from being removed, and/or the outlet subassembly 22 from being pulled off, from the container body 20 without the tamperproof seal 34 being removed. The protective cap 3, in addition, is configured such that it is possible for the protective cap 3 to be repeatedly removed from the dispenser 2 and be placed in position with clamping action thereon. For this purpose, the protective cap 3 is deformed to a slight extent when being placed in position, and therefore the elastic restoring forces of a protective cap 3 produced from plastics material generate a clamping action. In other configurations, latching elements are provided for this purpose.

(15) According to the application, the protective cap 3 has a sterile filter 5, which covers the ventilation openings 30 and prevents, or at least reduces, the introduction of germs into an interior 31 of the protective cap 3 via the ventilation openings 30. The sterile filter 5 has a cutoff of at most 0.2 μm, and therefore bacteria of a size of approximately 0.2 to approximately 5 μm are reliably held back.

(16) In the exemplary embodiment illustrated, the sterile filter 5 is arranged parallel to the cover portion 33 of the protective cap 3, on an inner side of the cover portion 33, and covering the ventilation openings 30. For fastening the sterile filter 5, in the exemplary embodiment illustrated, latching arms 37 are provided on the protective cap 3, on the inner side of the cover portion 33. The latching arms 37 project from the cover portion 33 in the longitudinal direction of the protective cap 3. For the purpose of fitting the sterile filter 5, the latching arms 37 are deformed elastically.

(17) As can be seen in FIG. 2, when the protective cap 3 has been placed in position, the sterile filter 5 is in contact with a point at the top of the dispenser 2, assigned to the exit opening 24. A material of the sterile filter 5 is selected here such that the sterile filter 5 can also be utilized as an absorber surface for rapid distribution of the residual droplet remaining in the region of the exit opening 24, and thus for rapid drying. In one configuration, the sterile filter 5, for this purpose, is designed in the form of a hydrophilic polymer membrane made of a membrane polymer from the group comprising polysulfone, polyethersulfone, cellulose, cellulose derivatives, polyvinylidene fluoride, polyamide, polyester and polyacrylonitrile and/or combinations thereof. The sterile filter 5 illustrated is made of a material which has a sufficient level of strength for it to be possible for the sterile filter 5 to be latched into the latching arms 37.

(18) FIGS. 3 and 4 show a discharging device 1 comprising a dispenser 2 according to FIG. 1 and a protective cap 3 similar to FIG. 2 in an overall perspective illustration and a sectional illustration, respectively. For a description of the dispenser 2, you are referred to the text above. The protective cap 3 according to FIGS. 3 and 4 likewise corresponds essentially to the protective cap 3 according to FIG. 2, and like reference signs are used for the same or similar components.

(19) In contrast to the embodiment according to FIG. 2, the sterile filter 5 according to FIGS. 3 and 4 is fitted on a carrier layer 50. A material of the carrier layer 50 is selected such that the carrier layer 50 imparts a higher level of mechanical strength to the sterile filter 5 connected to it. In advantageous configurations, the carrier layer 50 is likewise produced from a hydrophilic material, so as to ensure sufficient discharge of moisture to the surroundings via the carrier layer 50. In the exemplary embodiment illustrated, the carrier layer 50 is arranged on an outer side of the sterile filter 5, said outer side being directed toward the surroundings. In other configurations, the carrier layer 50 is arranged on an inner side of the sterile filter 5, said inner side being directed toward the interior 31 of the protective cap 3.

(20) FIGS. 5 and 6 show a discharging device 1 comprising a dispenser 2 according to FIG. 1 and a further configuration of a protective cap 3 similar to FIG. 2 in an overall perspective illustration and a sectional illustration, respectively. For a description of the dispenser 2, you are referred to the text above. The protective cap 3 according to FIGS. 5 and 6 likewise corresponds essentially to the protective cap 3 according to FIG. 2, and like reference signs are used for the same or similar components.

(21) In contrast to the embodiment according to FIG. 2, the protective cap 3 has four ventilation openings 30.

(22) As described above, advantageous configurations make provision, when the protective cap 3 has been placed in position, for the sterile filter 5 to be in contact with a point at the top of the dispenser 2, assigned to the exit opening 24. In order to force the sterile filter 5 into contact with the point at the top of the dispenser, the protective cap 3 according to FIGS. 5 and 6 has a stop 38, which projects from the inner side of the cover portion 33. Fastening the sterile filter 5 by means of the latching arms 37 and the stop 38 maximizes a free surface area of the sterile filter 5. This optimizes an absorber effect and drying of the dispenser by means of the sterile filter 5.

(23) In order to reduce the introduction of germs, and thus the loading to which the membrane is subjected, during relatively long-term storage, during storage in surroundings containing lots of germs and/or prior to the dispenser being used for the first time, provision is made, in one configuration, for an additional cover cap (not illustrated), to be fitted over the protective cap 3. For fastening of said cover cap (not illustrated), the protective cap 3 according to FIGS. 5 and 6 has accommodating openings 39.