Nano-Emulsion Cosmetic Composition In Which High Content Oils Are Stabilized

Abstract

The present invention relates to a translucent or semi-translucent nano-emulsion cosmetic composition, having excellent stability, comprising high content oils (5 to 30%) and, more specifically, to a nano-emulsion cosmetic composition having a physical property of low viscosity (5000 cps or less) with a translucent or semi-translucent appearance by preparing pre-emulsion by applying an emulsifier and then secondly passing the pre-emulsion through a high pressure homogenizer, and a method for preparing the same.

Claims

1. A method of preparing a translucent or semi-translucent nano-emulsion cosmetic composition, comprising: 1) mixing water with a polyol or a derivative thereof; 2) mixing an oil that is one or more selected from the group consisting of a silicone oil, an ester-based oil and a hydrocarbon-based oil with an emulsifier; and 3) mixing the mixture of 1) with the mixture of 2), and then high-pressure emulsifying the resulting mixture; wherein the oil is contained at 5 to 30 wt % based on a total weight of the nano-emulsion cosmetic composition; wherein the emulsifier contains polyglyceryl 10-stearate; and wherein the high-pressure emulsification is performed two times or more, resulting in a nano-emulsion having a particle size distribution of 10 to 250 nm.

2. The method according to claim 1, wherein the nano-emulsion cosmetic composition does not include a thickening agent.

3. The method according to claim 1, wherein the emulsifier is contained at 1 to 10 wt % with respect to the total weight of the nano-emulsion cosmetic composition.

4. The method according to claim 1, wherein the silicone oil is one or more selected from the group consisting of dimethicone, cyclomethicone, polydimethylsiloxane, methylphenylpolysiloxane, methylcyclopolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, tetradecamethylhexasiloxane and octamethyltrisiloxane.

5. The method according to claim 1, wherein the ester-based oil is any one selected from the group consisting of triethylhexanoin, cetyl ethylhexanoate, cetyl octanoate, cetyl isooctanoate, octyldodecyl myristate, pentaerythrityl tetraethyl hexanoate, isopropyl palmitate, isopropyl myristate, caprylic/capric triglyceride, butylene glycol dicaprylate/dicaprate, tocopherol acetate and dicaprylyl carbonate.

6. The method according to claim 1, wherein the hydrocarbon-based oil is one or more selected from the group consisting of paraffin, ceresin and microcrystalline wax.

7. The method according to claim 1, wherein the polyol or the derivative thereof is one or more selected from the group consisting of glycerin, a monohydric alcohol, and a dihydric alcohol.

8. The method according to claim 1, wherein the polyol or the derivative thereof is contained at 1 to 30 wt % based on the total weight of the nano-emulsion cosmetic composition.

9. The method according to claim 1, wherein the nano-emulsion has a viscosity of 0 to 5000 cps.

10. The method according to claim 1, wherein the nano-emulsion has an average particle size of 10 to 250 nm.

11. The method according to claim 1, wherein the high-pressure emulsification is performed under a pressure of 500 to 2500 bar.

Description

DESCRIPTION OF DRAWINGS

[0020] FIG. 1 illustrates the sizes of nano-emulsion particles according to Example 1.

[0021] FIG. 2 illustrates the result of assessing stability with transparency before passing through a high pressure homogenizer, after passing through a high pressure homogenizer one time, and after passing through a high pressure homogenizer second times in preparation of a nano-emulsion according to Example 1.

[0022] FIG. 3 illustrates the result of assessing transparency in Comparative Examples 1 to 3.

MODES OF THE INVENTION

[0023] The present invention provides a translucent or semi-translucent nano-emulsion cosmetic composition, which includes: water; a polyglyceryl-based emulsifier; one or more high content oils selected from the group consisting of silicone oil, ester-based oil and hydrocarbon-based oil; and a polyol or polyol derivative.

[0024] The polyglyceryl-based emulsifier may be, for example, polyglyceryl 10-stearate, polyglyceryl-3-caprate, polyglyceryl-3-diisostearate, or polyglyceryl-3 methylglucose distearate, but the present invention is not limited thereto.

[0025] The polyglyceryl-based emulsifier may be included at 1 to 10 wt % with respect to the total weight of the cosmetic composition. Outside the above-mentioned range, the cosmetic composition may have neither a sufficient hardness nor an opaque appearance.

[0026] A type of oil used herein is not particularly limited as long as it is conventionally used in preparation of an O/W emulsion composition, and for example, any one or more selected from the group consisting of silicone oil, ester-based oil and hydrocarbon-based oil may be used.

[0027] The silicone oil may be one or more selected from the group consisting of dimethicone, cyclomethicone, polydimethylsiloxane, methylphenylpolysiloxane, methylcyclopolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, tetradecamethylhexasiloxane and octamethyltrisiloxane, but the present invention is not limited thereto.

[0028] The ester-based oil may be any one selected from the group consisting of triethylhexanoin, cetyl ethylhexanoate, cetyl octanoate, cetyl isooctanoate, octyldodecyl myristate, pentaerythrityl tetraethyl hexanoate, isopropyl palmitate, isopropyl myristate, caprylic/capric triglyceride, butylene glycol dicaprylate/dicaprate, tocopherol acetate and dicaprylyl carbonate, but the present invention is not limited thereto.

[0029] The hydrocarbon-based oil may be one or more selected from the group consisting of paraffin, ceresin and microcrystalline wax, but the present invention is not limited thereto.

[0030] The oil may be contained at 5 to 30 wt % based on the total weight of the composition. Here, the term “content of oil” refers to the total weight of an oil phase component which does not contain an emulsion stabilizer. When the oil content is less than 5 wt %, the cosmetic composition can be easily obtained without significant differences in appearance and texture from a conventional skin lotion-type cosmetic composition, and when the oil content is more than 30 wt %, due to larger emulsion particles, emulsion stability may be degraded.

[0031] In the present invention, as high content oil is used, even when 5 wt % or more of the oil is used, a stabilized translucent or semi-translucent emulsion preparation is prepared. According to a conventional technique, stability/translucence was not ensured, and the conventional technique relates to a composition generally containing a low content of oil, such as less than 5%, which is used in nano-emulsification.

[0032] The polyol or a derivative thereof may be glycerin, a monohydric or dihydric alcohol or a mixture thereof. More specifically, the polyol or a derivative thereof may be one or more selected from the group consisting of butylene glycol, glycerin, propylene glycol, dipropylene glycol, propanediol, hexanediol, and a mixture thereof. Specifically, the polyol or polyol derivative included in the composition according to the present invention may be, for example, a mixture of glycerin and 1,2-hexanediol, but the present invention is not limited thereto.

[0033] The polyol or polyol derivative may be contained at 1 to 30 wt % based on the total weight of the composition. When the content of the polyol or derivative thereof is less than 1 wt %, skin moisturizing efficiency may be lacking, and when the content of the polyol or derivative thereof is more than 30 wt %, degradation in texture and skin irritation may occur.

[0034] In some cases, the composition according to the present invention may further include a pigment, a fragrance, a preservative or a thickening agent as an auxiliary component used in preparation of an O/W nano-emulsion composition. Here, a content of the auxiliary component may be 0 to 20 wt % based on the total weight of the composition.

[0035] The water used herein may be contained as the remainder in the composition, based on the total weight of the composition.

[0036] In addition, the nano-emulsion according to the present invention may be any one that has low enough viscosity to achieve desired dispersibility to increase the content of an internal phase and effectively deliver an active ingredient, without particular limitation, and for example, the nano-emulsion according to the present invention may have a viscosity of 5000 cps or less, specifically, 3000 cps or less, and more specifically, 2000 cps or less. The emulsion having “low viscosity” includes emulsions which have very low viscosity which cannot be experimentally measured and emulsions which have the above-mentioned range of viscosity. When the viscosity is not experimentally measured, since the viscosity may be 0, the viscosity may be in a range of, for example, 0 to 5000 cps, specifically, 1 to 3000 cps, and more specifically 5 to 2000 cps.

[0037] The emulsion is not particularly limited as long as it has a nano size, is enhanced in stability thereof and has low viscosity, and the average size may be, for example, 250 nm or less, and specifically, 200 nm or less. The emulsion may have any size included in the above-mentioned range of the average size, and the average size may be in a range of, for example, 10 to 250 nm, and specifically, 20 to 200 nm. At this time, the particle size distribution may be broadly 10 to 250 nm, and specifically 50 to 150 nm, which is very narrow. Therefore, a nano-emulsion composition which has excellent stability and a light texture may be provided.

[0038] The emulsion composition may exhibit a translucent or semi-translucent appearance. When conventional emulsification or simply high-pressure emulsification is only applied, it is easy to achieve a milky or cloudy appearance, but it is difficult to exhibit a translucent or semi-translucent appearance. However, the emulsion composition according to the present invention may have a translucent or semi-translucent appearance like a low viscosity skin lotion and also obtain a nutritive texture, which is opposite to that of a skin lotion, using high content oil.

[0039] The cosmetic composition according to the present invention has no limitation in its formulation, may be used on skin, a mucous membrane, the scalp or hair, and may be formulated as, for example, a basic cosmetic such as a softening toner, a nourishing toner, a lotion, a cream, a pack, a gel, a patch or a spray (mist); a color cosmetic such as a lipstick, a makeup base or a foundation; a cleansing cosmetic such as a shampoo, a rinse, a body cleanser, a toothpaste or a mouthwash; a hair fixative such as a hair tonic, a hair gel or a hair mousse; or a cosmetic composition for hair such as a hair restorer or a hair colorant. In addition, the cosmetic composition according to the present invention may be widely applied to medicines and quasi-drugs, including a lotion, an ointment, a gel, a cream, a patch or a spray.

[0040] In addition, the present invention provides a method of preparing a translucent or semi-translucent nano-emulsion cosmetic composition by applying emulsification and high-pressure emulsification to the composition.

[0041] Specifically, the present invention may provide a method of preparing a translucent or semi-translucent nano-emulsion cosmetic composition, which includes: mixing water with a polyol or polyol derivative; mixing one or more oils selected from the group consisting of silicone oil, ester-based oil and hydrocarbon-based oil with a polyglyceryl-based emulsifier; and mixing the mixture of 1) with the mixture of 2), and then high-pressure emulsifying the resulting mixture.

[0042] In addition, the same contents as those for the above cosmetic composition may be applied to the components described in the preparation method.

[0043] The high-pressure emulsification may be performed under a pressure of 500 to 2500 bar. When the pressure is less than 500 bar, the transparency and stability of the appearance cannot be expected, thereby having a problem in formation of a proper nano-emulsion, and when the pressure is more than 2500 bar, it may pose a risk on a high pressure homogenizer, which can be a problem for continuous production.

[0044] In addition, when the high-pressure emulsification is performed two or more times, stabilized particles having an average particle size of 20 to 250 nm may be obtained.

EXAMPLES

[0045] Hereinafter, the present invention will be described in detail with reference to examples to help in understanding the present invention. However, examples according to the present invention may be modified in a variety of different forms, and it should not be construed that the scope of the present invention is not limited to the following examples. The examples of the present invention are provided to more completely explain the present invention to those of ordinary skill in the art.

Example 1 and Comparative Examples 1 to 3: Preparation of O/W Nano-Emulsion Cosmetic Composition

[0046] In Example 1 and Comparative Examples 1 to 3, cosmetic compositions were prepared by the following method according to components and contents listed in Table 1 below.

[0047] As shown in Table 1 below, first, raw material of the first part were measured, stirred with a disper, and then heated (75° C.). Afterward, raw materials of the second part were measured/stirred, heated (75° C.), mixed with the raw materials of the first part previously prepared, and then stirred using a Homo-mixer at 3000 rpm for 5 minutes. Raw materials of the third part were input at 50° C., stirred under the same conditions (3000 rpm/5 minutes), and then cooled to 30° C. The resultant products passed through an M-110P Microfluidizer™ high pressure homogenizer two times under 1000 bar, and cooled to 30° C.

[0048] At this time, instead of a Homo-mixer used in a conventional emulsification system, a high pressure homogenizer was used.

[0049] According to the change in the process, physical or physicochemical properties of emulsion particles may be changed.

TABLE-US-00001 TABLE 1 Classification Name of Comparative Comparative Comparative (wt %) raw materials Example 1 Example 1 Example 2 Example 3 First part Water to 100 to 100 to 100 to 100 Glycerin 8 8 8 8 1,2-hexanediol 2 2 2 2 Second part Polyglyceryl-10 5 0 0 0 stearate Polysorbate 60 0 5 0 0 Sorbitan stearate/ 0 0 5 0 PEG-40 stearate Lecithin 0 0 0 5 Cetyl ethylhexanoate 5 5 5 5 Dimethicone 5 5 5 5 Third part Ethanol 5 5 5 5 Fragrance 0.1 0.1 0.1 0.1

Experimental Example 1: Evaluation of Stability

[0050] FIG. 1 illustrates the sizes of the nano-emulsion particles of Example 1, which passed through the Homo-mixer and then the high pressure homogenizer two times. This result shows that an average particle size is approximately 100 nm. Conventionally, when the particle size is 200 nm or less, the particles appear translucent and bluish, and thus it can be easily determined by visual observation that a nano emulsion was well prepared. In addition, in the evaluation of formulation stability, it can be determined that, when the translucent appearance was maintained as it was immediately after the preparation, stability is maintained. Here, a particle size was measured using a particle size analyzer (Submicron Particle Sizer NICOMP 380).

[0051] At this time, a particle size may vary according to experimental conditions (the contents of components in a composition, the number of times passing through a high pressure homogenizer, etc.). Such measurement of a particle size may be used as another reliable method for judging the stability of a formulation as well as easy judgment by visual observation.

Experimental Example 2: Confirmation of Transparency

[0052] An emulsion was prepared according to Example 1, transparency after storage at 40° C. for 30 days was visually observed, and the result is shown in FIG. 2.

[0053] In addition, Comparative Examples 1 to 3 passing through the high pressure homogenizer two times showed an opaque appearance unlike the example, and the result is shown in FIG. 3.

Experimental Example 3: Confirmation of Viscosity

[0054] The viscosity of a product was measured using a Brookfield DV-E viscometer, and expressed in units of centipoise (cps). The viscosity of a sample measured in this experiment is shown in Table 2 below.

Experimental Example 4: Confirmation of Texture

[0055] A portion (approximately 0.5 ml) of each of the emulsion compositions of Example 1 and Comparative Examples 1 to 3 was applied to the back of a hand, and then various aspects of sensory quality, including appearance, spreadability, moistness, oiliness, stickiness, wearability, absorptivity, feel after use, persistency, etc. were assessed, thereby evaluating overall product satisfaction. The texture/characteristics of the example and the comparative examples are shown in Table 2 below.

TABLE-US-00002 TABLE 2 Comparative Comparative Comparative Classification Example 1 Examples 1 Examples 2 Examples 3 Appearance translucent opaque opaque opaque Viscosity (cps) 800 cps 7500 cps 5500 cps 6500 cps Texture/ Changed in Sticky Sticky Considerably characteristics texture: emulsion emulsion sticky starting with greater with emulsion with rich oiliness than smooth moistness and moistness spreadability finishing with concentrated oiliness Stability Stable Unstable Unstable Unstable Refer to Refer to Refer to Refer to FIG. 2 FIG. 3 FIG. 3 FIG. 3