HEAT TRANSFER LIQUID FOR A TEMPERATURE CONTROL DEVICE FOR EXTRACORPOREAL CIRCULATION

Abstract

The present application refers to a heat transfer liquid for a temperature control device for human body temperature control during extracorporeal circulation, a temperature control device, the use of heat transfer liquid for extracorporeal circulation and a method of human body temperature control using a heat transfer liquid. The head transfer liquid consists of ethylene glycol or propylene glycol at about 25 volume-percent to about 35 volume-percent, hydrogen peroxide at 0.05 volume-percent or less and sterile, filtered and de-mineralized water as rest.

Claims

1. A temperature control system for human body temperature control during extracorporeal circulation, comprising: a temperature control liquid including sterile, filtered and demineralized water, and a disinfectant to inhibit microbial growth; a temperature control device adapted to heat or cool the temperature control liquid; at least one disinfectant sensor for measuring a concentration of the disinfectant in the temperature control liquid; a heat exchanger having a blood flow portion and a temperature control liquid flow portion, the heat exchanger configured to alter the temperature of blood flowing through the blood flow portion; and a computer coupled to the disinfectant sensor, the computer configured to indicate a measured concentration of disinfectant in the temperature control liquid, and to indicate a disinfection status of the temperature control liquid; wherein the temperature control system is adapted to heat or cool the heat transfer liquid based on an input provided by a user to the computer.

2. The temperature control system of claim 1, further comprising first and second displays, the computer configured to control the first display to display the measured concentration of disinfectant and to control the second display to indicate the disinfection status.

3. The temperature control system of claim 1, wherein the disinfection status includes a recommendation to add more disinfectant.

4. The temperature control system of claim 1, wherein the disinfection status includes a recommendation to exchange the temperature control liquid.

5. The temperature control system of claim 1, wherein the heat exchanger includes an open reservoir where the temperature control liquid is exposed to environmental air.

6. The temperature control system of claim 5, further comprising exchangeable conduits configured to be coupled to the open reservoir.

7. The temperature control system of claim 1, wherein the disinfectant includes at least 25 volume percent of ethylene glycol or propylene glycol.

8. The temperature control system of claim 7, wherein the disinfectant includes no more than 35 volume percent of ethylene glycol or propylene glycol.

9. The temperature control system of claim 7, wherein the disinfectant includes hydrogen peroxide.

10. The temperature control system of claim 9, wherein the disinfectant includes to 0.03 volume percent hydrogen peroxide.

11. The temperature control system of claim 9, wherein the disinfectant includes 30 volume percent of ethylene glycol or propylene glycol, and 0.02 volume percent hydrogen peroxide.

12. The temperature control system of claim 1 wherein the heat exchanger has a first inlet to receive the heat transfer liquid and a first outlet to remove heat transfer liquid and further wherein the heat exchanger has a second inlet to receive blood from the human body and a second outlet to remove the blood from the heat exchanger.

13. A temperature control system for human body temperature control during extracorporeal circulation, comprising: a temperature control liquid including sterile, filtered and demineralized water, and a disinfectant to inhibit microbial growth, wherein the disinfectant includes both hydrogen peroxide and ethylene glycol or propylene glycol; a temperature control device adapted to heat or cool the temperature control liquid; at least one disinfectant sensor for measuring a concentration of the disinfectant in the temperature control liquid; a heat exchanger having a blood flow portion and a temperature control liquid flow portion, the heat exchanger configured to alter the temperature of blood flowing through the blood flow portion; and a computer coupled to the disinfectant sensor, the computer configured to indicate a measured concentration of disinfectant in the temperature control liquid, and to indicate a disinfection status of the temperature control liquid, wherein the disinfection status includes a recommendation to add more disinfectant or to exchange the temperature control liquid; wherein the temperature control system is adapted to heat or cool the heat transfer liquid based on an input provided by a user to the computer.

14. The temperature control system of claim 13, further comprising first and second displays, the computer configured to control the first display to display the measured concentration of disinfectant and to control the second display to indicate the disinfection status.

15. The temperature control system of claim 13, wherein the heat exchanger includes an open reservoir where the temperature control liquid is exposed to environmental air.

16. The temperature control system of claim 15, further comprising exchangeable conduits configured to be coupled to the open reservoir.

17. The temperature control system of claim 13, wherein the ethylene glycol or propylene glycol is present in a concentration of at least 25 volume percent.

18. The temperature control system of claim 17, wherein the ethylene glycol or propylene glycol is present in a concentration of no more than 35 volume percent.

19. The temperature control system of claim 17, wherein the hydrogen peroxide is present in a concentration of 0.01 to 0.03 volume percent.

20. The temperature control system of claim 19, wherein the ethylene glycol or propylene glycol is present in a concentration of 30 volume percent, and the hydrogen peroxide is present in a concentration of 0.02 volume percent.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0019] FIG. 1 shows a schematic diagram illustrating a temperature control device in a heat exchanging system.

DETAILED DESCRIPTION OF PREFERRED EMBODIMENT

[0020] FIG. 1 shows a schematic diagram of a heat exchanger 10 for human body temperature control during extracorporeal circulation. The heat exchanger 10 comprises a blood side 12 and a heat transfer liquid side 14 in which blood and a heat transfer liquid are respectively circulated.

[0021] The temperature of the heat transfer liquid used in the heat exchanger 10 is controlled by a heater and/or cooler 24, i.e. a temperature control device. The heater and/or cooler 24 is a device which is capable of heating or cooling or heating and cooling the heat transfer liquid. Preferably, the heater or cooler is capable of both heating and cooling the heat transfer liquid so that a defined temperature of the heat transfer liquid can be maintained. The heater and/or cooler 24 is part of a heat transfer liquid side circuit 26 in which the heat transfer liquid is circulated for operating the heat exchanger 10 in controlling the temperature of the human body of a patient.

[0022] The heater and/or cooler 24 may be provided with a disinfectant sensor 16 configured for measuring a concentration of a disinfectant in the heat transfer liquid in the heater and/or cooler 2. The result of the measurement of the sensor 16 may be transmitted to a computer 18 which may control a first display 20 which may indicate the measured concentration of disinfectant in the heat transfer liquid and a second display 22 which may indicate the consequence of the measured concentration. In particular, the second display 22 may indicate whether the disinfection status of the heat transfer liquid is ok, whether disinfectant is to be added or whether the heat transfer liquid is to be exchanged.

[0023] The heat transfer liquid circulated in the heat transfer liquid side circuit 26 of the present embodiment consists of ethylene glycol or propylene glycol at 30 volume-percent, hydrogen peroxide at 0.02 volume-percent and sterile, filtered and de-mineralized water as rest. In particular the hydrogen peroxide may be considered by the sensor 16 as disinfectant and a concentration of hydrogen peroxide may be measured by the sensor 16. But also a concentration of ethylene glycol or propylene glycol can be determined by the sensor 16 or a different sensor.

[0024] Measuring the concentration of disinfectant, be it hydrogen peroxide, ethylene glycol or propylene glycol is, however, optional and not essential for the present disclosure.