ICE CATHETER WITH MULTIPLE TRANSDUCER ARRAYS
20210177379 · 2021-06-17
Inventors
- Alexander Franciscus Kolen (Eindhoven, NL)
- Cornelis Pieter Janse (Eindhoven, NL)
- Harm Jan Willem Belt (Weert, NL)
- Harold Agnes Wilhelmus Schmeitz (Eindhoven, NL)
- Bart Leonardus Martinus SMEETS (MEIJEL, NL)
- Franciscus Hendrikus Van Heesch (Valkenswaard, NL)
Cpc classification
A61B8/12
HUMAN NECESSITIES
A61B8/483
HUMAN NECESSITIES
A61B8/4477
HUMAN NECESSITIES
G01S15/8995
PHYSICS
A61B8/4494
HUMAN NECESSITIES
A61B8/5207
HUMAN NECESSITIES
International classification
A61B8/00
HUMAN NECESSITIES
A61B8/12
HUMAN NECESSITIES
Abstract
An ultrasound image compounding method that is suitable for use with an ICE catheter that includes a first ultrasound transceiver array and a second ultrasound transceiver array, the first ultrasound transceiver array and the second ultrasound transceiver array being axially separated along a length of the ICE catheter, is described. In the method, first array data corresponding to ultrasound signals detected by the first ultrasound transducer array in response to an insonification of a region of interest by the first ultrasound transducer array at a first insonification angle; and second array data corresponding to ultrasound signals detected by the second ultra- sound transducer array in response to an insonification of the region of interest by the second ultrasound transducer array at a second insonification angle; are received. A compound image corresponding to the region of interest is generating based on the first array data and the second array data.
Claims
1. An ultrasound image compounding method for use with an ICE catheter including a first ultrasound transceiver array and a second ultrasound transceiver array in which the first ultrasound transceiver array and the second ultrasound transceiver array are axially separated along a length axis of the ICE catheter; the method comprising the steps of: receiving, from the first ultrasound transceiver array, first array data corresponding to ultrasound signals detected by the first ultrasound transducer array in response to an insonification of a region of interest by the first ultrasound transducer array at a first insonification angle; receiving, from the second ultrasound transceiver array, second array data corresponding to ultrasound signals detected by the second ultrasound transducer array in response to an insonification of the region of interest by the second ultrasound transducer array at a second insonification angle; generating, based on the first array data and the second array data, a compound image corresponding to the region of interest.
2. The ultrasound image compounding method according to claim 1 wherein the first array data and the second array data both correspond to an imaging plane passing through and parallel to the length axis of the ICE catheter, and/or the first insonification angle and the second insonification angle are in the imaging plane, and/ or wherein the region of interest includes a plurality of points, each point being insonified by the first ultrasound transducer array and by the second ultrasound transducer array from two different insonification angles.
3. The ultrasound image compounding method according to claim 1 wherein the generating includes: weighting the first array data and the second array data at corresponding positions in the region of interest; and summing the weighted first array data and the weighted second array data at the corresponding positions to provide the compound image.
4. The ultrasound image compounding method according to claim 1 wherein the generating includes: reconstructing a first ultrasound image based on the first array data, the first ultrasound image including first ultrasound image intensity data; reconstructing a second ultrasound image based on the second array data, the second ultrasound image including second ultrasound image intensity data; weighting the first ultrasound image intensity data and the second ultrasound image intensity data at corresponding positions in the region of interest; and summing the weighted first ultrasound image intensity data and the weighted second ultrasound image intensity data at the corresponding positions to provide the compound image.
5. The ultrasound image compounding method according to claim 1 wherein the generating includes: comparing the first array data and the second array data at corresponding positions in the region of interest and selecting the largest value of said data at each corresponding position to provide the compound image.
6. The ultrasound image compounding method according to claim 1 wherein: the first array data includes temporal ultrasound signals corresponding to each of a plurality of image scan lines at the first insonification angle; the second array data includes temporal ultrasound signals corresponding to each of a plurality of image scan lines at the second insonification angle; wherein the generating includes: band pass filtering, at each of a plurality of central frequencies, the temporal ultrasound signals corresponding to each of a plurality of image scan lines at the first insonification angle and computing for each image scan line, a weighted average of the band pass filtered ultrasound signals; band pass filtering, at each of a plurality of central frequencies, the temporal ultrasound signals corresponding to each of a plurality of image scan lines at the second insonification angle and computing for each image scan line, a weighted average of the band pass filtered ultrasound signals; and summing the weighted average of the band pass filtered ultrasound signals at the first insonification angle and the weighted average of the band pass filtered ultrasound signals at the second insonification angle at corresponding positions in the region of interest to provide the compound image.
7. The ultrasound image compounding method according to claim 1 wherein the first ultrasound transceiver array and the second ultrasound transceiver array have a mutual spatial arrangement; and wherein the step of generating is based further on the mutual spatial arrangement.
8. The ultrasound image compounding method according to claim 7 further comprising the steps of: receiving, from the first ultrasound transceiver array, first array tracking data corresponding to ultrasound signals detected by the first ultrasound transducer array in response to ultrasound signals emitted by the second ultrasound transducer array; or receiving, from the second ultrasound transceiver array, second array tracking data corresponding to ultrasound signals detected by the second ultrasound transducer array in response to ultrasound signals emitted by the first ultrasound transducer array; and determining the mutual spatial arrangement based on the first array tracking data or the second array tracking data correspondingly.
9. The ultrasound image compounding method according to claim 7 wherein the ultrasound signals emitted by the second ultrasound transducer array correspond to at least one sidelobe of the insonification of the region of interest by the second ultrasound transducer array at the second insonification angle; or wherein the ultrasound signals emitted by the first ultrasound transducer array correspond to at least one sidelobe of the insonification of the region of interest by the first ultrasound transducer array at the first insonification angle; correspondingly.
10. The ultrasound image compounding method according to claim 8 wherein the step of determining the mutual spatial arrangement based on the corresponding first array tracking data or the corresponding second array tracking data, comprises: for the first array tracking data, computing at least one distance between the first ultrasound transceiver array and the second ultrasound transceiver array based on a time of flight of the ultrasound signals detected by the first ultrasound transducer array in response to ultrasound signals emitted by the second ultrasound transducer array, and comprises for the second array tracking data, computing at least one distance between the first ultrasound transceiver array and the second ultrasound transceiver array based on a time of flight of the ultrasound signals detected by the second ultrasound transducer array in response to ultrasound signals emitted by the first ultrasound transducer array.
11. The ultrasound image compounding method according to claim 8 wherein: the ultrasound signals emitted by the second ultrasound transducer array form a hemispherical wave front radiating outwardly with respect to the second ultrasound transducer array, wherein the first array tracking data corresponds to time of flight data indicative of a distance between the second ultrasound transducer array and each of a plurality of array elements of the first ultrasound transceiver array, and wherein the mutual spatial arrangement is determined based on the first array tracking data by triangulating the position of each of the plurality of array elements of the first ultrasound transceiver array respective the second ultrasound transducer array; or wherein the ultrasound signals emitted by the first ultrasound transducer array form a hemispherical wave front radiating outwardly with respect to the first ultrasound transducer array, wherein the second array tracking data corresponds to time of flight data indicative of a distance between the first ultrasound transducer array and each of a plurality of array elements of the second ultrasound transceiver array, and wherein the mutual spatial arrangement is determined based on the second array tracking data by triangulating the position of each of the plurality of array elements of the second ultrasound transceiver array respective the first ultrasound transducer array; correspondingly.
12. The ultrasound image compounding method according to claim 7 wherein the ICE catheter further includes either i) a bend sensor such as a strain gauge such as a fiber Bragg grating, or a capacitive position sensor, the bend sensor being configured to provide bend data indicative of a bend of the ICE catheter between the first ultrasound transceiver array and the second ultrasound transceiver array, or ii) a bend actuator configured to provide a desired bend and corresponding bend data indicative of a bend of the ICE catheter between the first ultrasound transceiver array and the second ultrasound transceiver array; and wherein the method further comprises the step of receiving the bend data and determining the mutual spatial arrangement based on a model configured to predict the mutual spatial arrangement based on the bend data.
13. The ultrasound image compounding method according to claim 7 wherein the first ultrasound transceiver array is a two-dimensional array for generating a volumetric ultrasound image, and wherein the mutual spatial arrangement is determined by: reconstructing a volumetric ultrasound image based on the first array data, the volumetric ultrasound image comprising a plurality of two-dimensional image slices; reconstructing a planar ultrasound image based on the second array data; and matching one of the plurality of two-dimensional image slices to the planar ultrasound image based on at least one image feature in the region of interest.
14. Computer program product comprising instructions which when executed on a processor are configured to cause the processor to carry out the method steps according to claim 1.
15. An ICE catheter for use with the method according to claim 1, the ICE catheter including a first ultrasound transceiver array and a second ultrasound transceiver array in which the first ultrasound transceiver array and the second ultrasound transceiver array are axially separated along a length axis of the ICE catheter.
16. The ICE catheter according to claim 15 wherein the the first ultrasound transceiver array is configured to generate first array data corresponding to ultrasound signals detected by the first ultrasound transducer array in response to an insonification of a region of interest by the first ultrasound transducer array at a first insonification angle; and wherein the second ultrasound transceiver array is configured to generate second array data corresponding to ultrasound signals detected by the second ultrasound transducer array in response to an insonification of the region of interest by the second ultrasound transducer array at a second insonification angle; and wherein the first array data and the second array data both correspond to an imaging plane passing through and parallel to the length axis of the ICE catheter, and/ or the first insonification angle and the second insonification angle are in the imaging plane, and/ or wherein the region of interest includes a plurality of points, each point being insonified by the first ultrasound transducer array and by the second ultrasound transducer array from two different insonification angles.
17. Ultrasound imaging arrangement comprising: the ICE catheter comprising a first ultrasound transceiver array and a second ultrasound transceiver array in which the first ultrasound transceiver array and the second ultrasound transceiver array are axially separated along a length axis of the ICE catheter; and a processor configured to execute the method according to claim 1.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0022]
[0023]
[0024]
[0025]
[0026]
[0027]
DETAILED DESCRIPTION OF EMBODIMENTS
[0028] In order to illustrate the principles of the present invention an ultrasound image compounding method is described with particular reference to an ICE catheter that is used to image cardiac structures. It is however to be appreciated that the ultrasound image compounding method also finds application with an ICE catheter that is used to image interventional devices such as an ablation catheter, a lasso catheter used for electrophysiological mapping of cardiac structures, and so forth. Moreover an ICE catheter is described that includes a first and a second ultrasound transducer array. The relative positions of the arrays, with the first ultrasound transducer array illustrated as being at the distal end of the catheter should not be interpreted as limiting. For example the relative positions of these arrays may be reversed such that the second ultrasound transducer array is at the distal end, or indeed the arrays may be positioned at other positions along the length of the ICE catheter than the distal end.
[0029] ICE is widely used during interventional cardiac procedures to visualize anatomical features such as the atrial septum, the aortic valve, pulmonary veins and so forth. As with other conventional ultrasound imaging systems, ICE suffers from two common image artifacts: speckle and shadow. One technique that is used in the ultrasound field to mitigate these artifacts is image compounding. Spatial compounding is a particular form of image compounding that involves the insonification of a region of interest at several incidence angles and combining the information into a single image. See for instance document “Multi-Angle Compound Imaging” by Jespersen, S. K. et al., Ultrasonic Imaging, Vol. 20, pages 81-102, 1998. In this regard,
[0030] Frequency compounding is another particular form of image compounding. Frequency compounding involves the insonification of the object at several frequencies and combining the information into a single image. See for instance the document “Phasing out speckle” by Gatenby, J. C., et al, Phys. Med. Biol., 1989, Vol. 34, No. 11, 1683-1689.
[0031] With reference to
[0032]
[0033] By so combining the data generated by axially-separated transducer arrays 210.sub.1, 210.sub.2, the resulting spatially-compounded image has reduced speckle. The speckle patterns from each array are averaged in the compound image, thereby reducing the variance of the speckle. Moreover the different insonification angles of the region of interest result in less shadowing behind acoustically-dense image features as compared to an ICE catheter that uses a single viewing angle or a single array. By reducing these image artifacts an improved ultrasound image is provided. The use of axially-separated transducer arrays 210.sub.1, 210.sub.2 advantageously increases the range of insonification angles θ.sub.1, θ.sub.2 that region of interest 221 can be subjected to, thereby further reducing shadowing. Moreover, the separate arrays 210.sub.1, 210.sub.2 may be operated simultaneously. This reduces the time to scan region of interest 221 across the desired angular range and thereby reduces image blurring caused by intra-scan motion of ICE catheter 220. When a flexible catheter is used for ICE catheter 220 a bend in ICE catheter 220 between the two arrays 210.sub.1, 210.sub.2 can be used to further reduce shadowing since this bend further increases the range of insonification angles that the region of interest can be subjected to. Such a flexible catheter is also termed a steerable catheter and may include a control unit configured to provide a desired bend. This facilitates e.g. the steering of the catheter around chambers in the heart.
[0034] Whilst an idealized array of parallel image scan lines 112.sub.1,n and 112.sub.2,n are illustrated in
[0035] ICE catheter 220 in
[0036] Ultrasound transducer arrays 210.sub.1, 210.sub.2 may be one-dimensional or two-dimensional arrays, each including a plurality of array elements. Thereto the arrays may, correspondingly be used to generate and detect ultrasound signals corresponding to either a planar or a volumetric, i.e. 3D ultrasound images. Moreover, more than two ultrasound transducer arrays may be included on catheter 220 in the same manner. In one embodiment described later, one of the arrays is a two-dimensional array and another of the arrays is either a one- or a two-dimensional array. The array elements may include for example piezoelectric material or may be membrane-based i.e. Capacitive Micro machined Ultrasonic Transducers, a technology referred-to as CMUT.
[0037] In accordance with one implementation the method step of generating 332 includes: weighting the first array data and the second array data at corresponding positions in the region of interest 221; and summing the weighted first array data and the weighted second array data at the corresponding positions to provide the compound image. In some instances equal weighting of the first and second array data may be used. Differing weighting values may alternatively be used.
[0038] In accordance with one implementation the method step of generating 332 includes: reconstructing a first ultrasound image based on the first array data, the first ultrasound image including first ultrasound image intensity data; reconstructing a second ultrasound image based on the second array data, the second ultrasound image including second ultrasound image intensity data; weighting the first ultrasound image intensity data and the second ultrasound image intensity data at corresponding positions in the region of interest 221; and summing the weighted first ultrasound image intensity data and the weighted second ultrasound image intensity data at the corresponding positions to provide the compound image. One of many known ultrasound image reconstruction techniques may be used, for example to reconstruct brightness, or B-mode ultrasound images that include the ultrasound image intensity data. Although other weighting factors may be used, preferably a weighting is used in which each of the two ultrasound images contribute equally to corresponding positions in the compound image.
[0039] In accordance with another implementation the method step of generating 332 includes: comparing the first array data and the second array data at corresponding positions in region of interest 221 and selecting the largest value of said data at each corresponding position to provide the compound image. This form of image compounding offers improved boundary definition at the expense of somewhat lowered speckle reduction.
[0040] In accordance with another implementation, frequency compounding may be used in combination with the above-described techniques of spatial compounding. Thereto, in this implementation the first array data includes temporal ultrasound signals corresponding to each of a plurality of image scan lines at the first insonification angle 112.sub.1,n; and the second array data includes temporal ultrasound signals corresponding to each of a plurality of image scan lines at the second insonification angle 112.sub.2,n. Moreover, the step of generating a compound image corresponding to the region of interest 221 includes: band pass filtering, at each of a plurality of central frequencies, the temporal ultrasound signals corresponding to each of a plurality of image scan lines at the first insonification angle 112.sub.1,n and computing for each image scan line, a weighted average of the band pass filtered ultrasound signals; band pass filtering, at each of a plurality of central frequencies, the temporal ultrasound signals corresponding to each of a plurality of image scan lines at the second insonification angle 112.sub.2,n and computing for each image scan line, a weighted average of the band pass filtered ultrasound signals; and summing the weighted average of the band pass filtered ultrasound signals at the first insonification angle 112.sub.1,n and the weighted average of the band pass filtered ultrasound signals at the second insonification angle 112.sub.2,n at corresponding positions in the region of interest 221 to provide the compound image. In so doing, additional speckle reduction may be achieved.
[0041] In accordance with another implementation, first ultrasound transceiver array 210.sub.1 and second ultrasound transceiver array 210.sub.2 have a mutual spatial arrangement. In this implementation the step of generating 332 is based further on the mutual spatial arrangement. In so doing, any changes in the mutual spatial arrangement can be accounted-for in the generated compound image.
[0042] In one embodiment of this mutual spatial arrangement implementation, array tracking data is generated by one or both of the ultrasound transceiver arrays 210.sub.1, 210.sub.2. In this embodiment an ultrasound transceiver array's tracking data is provided by ultrasound signals that are emitted by the other of the two ultrasound transceiver arrays. Thereto, the method may include the steps of: receiving, from first ultrasound transceiver array 210.sub.1, first array tracking data corresponding to ultrasound signals detected by the first ultrasound transducer array 210.sub.1 in response to ultrasound signals emitted by the second ultrasound transducer array 210.sub.2; or receiving, from the second ultrasound transceiver array 210.sub.2, second array tracking data corresponding to ultrasound signals detected by the second ultrasound transducer array 210.sub.2 in response to ultrasound signals emitted by the first ultrasound transducer array 210.sub.1; and determining the mutual spatial arrangement based on the first array tracking data or the second array tracking data correspondingly. An ultrasound transducer array's emitted signals may be dedicated tracking pulses, or indeed stray ultrasound signals such as a sidelobe of those that are used by that ultrasound transducer array to insonify the region of interest. The latter has the benefit of simplifying the control of the ultrasound signals emitted by an array because it involves detecting the other ultrasound transducer array's stray imaging signals. Such sidelobes are typically present as a result of the beamforming techniques that are used to insonify region of interest 221 at the respective insonification angle θ.sub.1, θ.sub.2. The benefit of using dedicated tracking pulses is that these may advantageously be directed towards the expected positon of the other, receiving, array, thereby minimizing the emitted ultrasound power. One example implementation of this mutual spatial arrangement is illustrated in
[0043] In
[0044] As illustrated in
[0045]
[0046] In another embodiment that is described with reference to
[0047] Any of the method steps presented herein, may be recorded in the form of instructions which when executed on a processor cause the processor to carry out such method steps. Thereto,
[0048] In summary, an ultrasound image compounding method has been described that is suitable for use with an ICE catheter that includes a first ultrasound transceiver array and a second ultrasound transceiver array, the first ultrasound transceiver array and the second ultrasound transceiver array being axially separated along a length of the ICE catheter. In the method, first array data corresponding to ultrasound signals detected by the first ultrasound transducer array in response to an insonification of a region of interest by the first ultrasound transducer array at a first insonification angle; and second array data corresponding to ultrasound signals detected by the second ultrasound transducer array in response to an insonification of the region of interest by the second ultrasound transducer array at a second insonification angle; are received. A compound image corresponding to the region of interest is generated based on the first array data and the second array data.
[0049] Various embodiments and implementations have been described in the above and it is noted that these may be combined to achieve further advantageous effects.