GENERAL-PURPOSE FLUORESCENT FLUID PHOTOCHEMICAL MICROREACTOR AND MANUFACTURING METHOD THEREFOR BY 3D PRINTING

Abstract

Disclosed are a general-purpose fluorescent fluid photochemical microreactor and a manufacturing method therefor by means of 3D printing, belonging to the technical field of photochemical reactor research. By using a transparent photosensitive resin and the strong space building capacity of 3D printing, a photochemical microreactor having both a light-collecting channel and a reaction channel is prepared. By means of introducing a light-collecting substance in a fluid form into a light channel, not only can play the role of light collection and wavelength conversion, which solves the difficulty of traditional photochemical reactors of light source matching, but also the light-collecting substance can be flexibly changed so as to meet the requirements of different photochemical reactions in the reaction channel, which greatly expands the application range of the reactor.

Claims

1. A 3D printing manufacturing method for general-purpose fluorescent fluid photochemical microreactor, wherein the microreactor comprises light channel, reaction channel, output of light channel, input of light channel, output of reaction channel and input of reaction channel; the light channel is filled with the fluorescent fluid, and two ports of the light channel are sealed; the reaction channel is filled with reactant solution, and the light channel is located around the reaction channel to ensure the occurrence of the photochemical reaction; the 3D printing manufacturing method comprises the steps as follows: (1) designing the model of the microreactor by using Solidworks software and printing it with a 3D printer, the tube diameter or cross-sectional side length of light channel and reaction channel are 0.5-1 mm, and the material is transparent photosensitive resin; (2) printing the microreactor by a UV curing 3D printer; (3) cleaning the microreactor with a mixture of ethanol and isopropanol, and ensuring that there is no resin residue in the channel, and then placing it under a UV lamp to cure for 2-10 hours; (4) dissolving the fluorescent material in a solvent with a concentration of 0.1-1000 ppm, and then using a syringe to inject it into the light channel and sealing the two ends tightly; then, a general-purpose fluorescent fluid photochemical microreactor is prepared.

2. The 3D printing manufacturing method for general-purpose fluorescent fluid photochemical microreactor according to claim 1, wherein the reaction channel and light channel are both serpentine square tubes, and the light channel are two sets, respectively arranged in parallel on the upper and lower sides of the reaction channel.

3. The 3D printing manufacturing method for general-purpose fluorescent fluid photochemical microreactor according to claim 1, wherein the reaction channel is a line square tube, and the light channel is a spiral round tube, which wraps around the outer circumference of the reaction channel.

4. The 3D printing manufacturing method for general-purpose fluorescent fluid photochemical microreactor according to claim 1, wherein the material of the general-purpose fluorescent fluid photochemical microreactor is transparent photosensitive resin.

5. The 3D printing manufacturing method for general-purpose fluorescent fluid photochemical microreactor according to claim 1, the fluorescent material in the fluorescent fluid is fluorescent dye, fluorescent quantum dot or nanocrystal, and the solvent is water, ethanol, isopropanol, acetonitrile, ethyl acetate, N, N-dimethylformamide, toluene or dichloromethane.

6. The 3D printing manufacturing method for general-purpose fluorescent fluid photochemical microreactor according to claim 4, the fluorescent material in the fluorescent fluid is fluorescent dye, fluorescent quantum dot or nanocrystal, and the solvent is water, ethanol, isopropanol, acetonitrile, ethyl acetate, N, N-dimethylformamide, toluene or dichloromethane.

7. (canceled)

8. The 3D printing manufacturing method for the general-purpose fluorescent fluid photochemical microreactor according to claim 1, wherein the layer printing accuracy selected by the 3D printer is 0.025-0.1 mm.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0018] FIG. 1 is a schematic diagram of a serpentine fluorescent fluid photochemical microreactor.

[0019] FIG. 2 is a schematic diagram of a spiral fluorescent fluid photochemical microreactor.

[0020] In Figures: 1 reaction channel; 2 light channel; 3 transparent photosensitive resin.

DETAILED DESCRIPTION

[0021] The present invention will be further described in detail below combined with the figures and technical solutions.

[0022] A method for preparing a general-purpose fluorescent fluid photochemical microreactor by using 3D printing technology, the specific steps are as follows:

Example 1 (Serpentine Microreactor)

[0023] (1) Design the model of the microreactor by using Solidworks software. Both the light microchannel and the reaction microchannel are serpentine square tubes with a side length of 1 mm and a channel length of 105 mm. The overall size of the reactor is 8.2 cm in length, 3 cm in width and 1.5 cm in height.

[0024] (2) Printed the microreactor by a UV curing 3D printer, its material is transparent photosensitive resin.

[0025] (3) After printing, remove the microreactor from the working platform and put it in a mixed solution of ethanol and isopropanol for cleaning. Pay special attention to cleaning the inside of the microchannel to ensure that there is no resin residue. Then placed the microreactor under a UV lamp and cured for 4 hours.

[0026] (4) The fluorescent dye Lumogen F Red 305 was dissolved in an ethanol solution at a concentration of 200 ppm, and it was injected into the light channel using a syringe.

[0027] (5) The fluorescent fluid photochemical microreactor is placed in a light-shielding cylinder wrapped with a blue LED light strip inside to form the final photochemical microreactor. For the catalytic oxidation of the diphenylanthracene, the reactants diphenylanthracene and the photocatalyst methylene blue can be injected into the reaction channel separately, and the oxidation conversion rate of the diphenylanthracene under the action of the fluorescent fluid is three times that of pure blue light.

Example 2 (Spiral Microreactor)

[0028] (1) Design the microreactor model by using SolidWorks software. The light microchannel is a spiral round tube with a tube diameter of 1 mm and a channel length of 105 mm. The reaction channel is a straight square tube with a side length of 1 mm and a channel length of 56 mm. The overall dimensions of the microreactor are 7 cm in length, 3.5 cm in width and 1.5 cm in height.

[0029] (2) Printed the microreactor by a UV curing 3D printer, its material is transparent photosensitive resin.

[0030] (3) After printing, remove the microreactor from the working platform and put it in a mixed solution of ethanol and isopropanol for cleaning. Pay special attention to cleaning the inside of the microchannel to ensure that there is no resin residue. Then placed the microreactor under a UV lamp and cured for 4 hours.

[0031] (4) The fluorescent dye fluorescein isothiocyanate (FITC) was dissolved in an ethanol solution at a concentration of 400 ppm, and injected into the light channel using a syringe.

[0032] (5) The fluorescent fluid photochemical microreactor is placed in a light-shielding cylinder wrapped with a blue LED light strip inside to form the final photochemical microreactor. For the oxidation reaction of p-methylthiophenol, the reactants p-methylthiophenol and the photocatalyst Eosin Y can be injected into the reaction channel separately, and the reaction conversion rate under the action of the fluorescent fluid is 1.8 times that of pure blue light.